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2015

Journal Article

Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury

Irvine, Katharine M., Clouston, Andrew D., Gadd, Victoria L., Miller, Gregory C., Wong, Weng-Yew, Melino, Michelle, Maradana, Muralidhara Rao, MacDonald, Kelli, Lang, Richard A., Sweet, Matthew J., Blumenthal, Antje and Powell, Elizabeth E. (2015). Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury. Fibrogenesis and Tissue Repair, 8 (19) 19, 19. doi: 10.1186/s13069-015-0036-7

Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury

2015

Journal Article

Effect of laparoscopic-assisted resection vs open resection on pathological outcomes in rectal cancer: the ALaCaRT randomized clinical trial

Stevenson, Andrew R. L., Solomon, Michael J., Lumley, John W., Hewett, Peter, Clouston, Andrew D., Gebski, Val J., Davies, Lucy, Wilson, Kate, Hague, Wendy and Simes, John (2015). Effect of laparoscopic-assisted resection vs open resection on pathological outcomes in rectal cancer: the ALaCaRT randomized clinical trial. JAMA - Journal of the American Medical Association, 314 (13), 1356-1363. doi: 10.1001/jama.2015.12009

Effect of laparoscopic-assisted resection vs open resection on pathological outcomes in rectal cancer: the ALaCaRT randomized clinical trial

2015

Journal Article

Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8<sup>+</sup> T cells that induce GVHD without antileukemic effects

Gartlan, Kate H., Markey, Kate A., Varelias, Antiopi, Bunting, Mark D., Koyama, Motoko, Kuns, Rachel D., Raffelt, Neil C., Olver, Stuart D., Lineburg, Katie E., Cheong, Melody, Teal, Bianca E., Lor, Mary, Comerford, Iain, Teng, Michele W. L., Smyth, Mark J., McCluskey, James, Rossjohn, Jamie, Stockinger, Brigitta, Boyle, Glen M., Lane, Steven W., Clouston, Andrew D., McColl, Shaun R., MacDonald, Kelli P. A. and Hill, Geoffrey R. (2015). Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8+ T cells that induce GVHD without antileukemic effects. Blood, 126 (13), 1609-1620. doi: 10.1182/blood-2015-01-622662

Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8<sup>+</sup> T cells that induce GVHD without antileukemic effects

2015

Journal Article

Acute GVHD results in a severe DC defect that prevents T-cell priming and leads to fulminant cytomegalovirus disease in mice

Wikstrom, Matthew E., Fleming, Peter, Kuns, Rachel D., Schuster, Iona S., Voigt, Valentina, Miller, Gregory, Clouston, Andrew D., Tey, Siok-Keen, Andoniou, Christopher E., Hill, Geoffrey R. and Degli-Esposti, Mariapia A. (2015). Acute GVHD results in a severe DC defect that prevents T-cell priming and leads to fulminant cytomegalovirus disease in mice. Blood, 126 (12), 1503-1514. doi: 10.1182/blood-2015-01-622837

Acute GVHD results in a severe DC defect that prevents T-cell priming and leads to fulminant cytomegalovirus disease in mice

2015

Journal Article

The Enhanced liver fibrosis score is associated with clinical outcomes and disease progression in patients with chronic liver disease

Irvine, Katharine M., Wockner, Leesa F., Shanker, Mihir, Fagan, Kevin J., Horsfall, Leigh U., Fletcher, Linda M., Ungerer, Jacobus P. J., Pretorius, Carel J., Miller, Gregory C., Clouston, Andrew D., Lampe, Guy and Powell, Elizabeth E. (2015). The Enhanced liver fibrosis score is associated with clinical outcomes and disease progression in patients with chronic liver disease. Liver International, 36 (3), 370-377. doi: 10.1111/liv.12896

The Enhanced liver fibrosis score is associated with clinical outcomes and disease progression in patients with chronic liver disease

2015

Journal Article

ELF score ≥9.8 indicates advanced hepatic fibrosis and is influenced by age, steatosis and histological activity

Fagan, Kevin J., Pretorius, Carel J., Horsfall, Leigh U., Irvine, Katharine M., Wilgen, Urs, Choi, Kihoon, Fletcher, Linda M., Tate, Jill, Melino, Michelle, Nusrat, Sharmin, Miller, Gregory C., Clouston, Andrew D., Ballard, Emma, O'Rourke, Peter, Lampe, Guy, Ungerer, Jacobus P. J. and Powell, Elizabeth E. (2015). ELF score ≥9.8 indicates advanced hepatic fibrosis and is influenced by age, steatosis and histological activity. Liver International, 35 (6), 1673-1681. doi: 10.1111/liv.12760

ELF score ≥9.8 indicates advanced hepatic fibrosis and is influenced by age, steatosis and histological activity

2015

Journal Article

Australian clinical practice guidelines for the diagnosis and management of Barrett's esophagus and early esophageal adenocarcinoma

Whiteman, David C., Appleyard, Mark, Bahin, Farzan F., Bobryshev, Yuri V., Bourke, Michael J., Brown, Ian, Chung, Adrian, Clouston, Andrew, Dickins, Emma, Emery, Jon, Eslick, Guy D., Gordon, Louisa G., Grimpen, Florian, Hebbard, Geoff, Holliday, Laura, Hourigan, Luke F., Kendall, Bradley J., Lee, Eric Y. T., Levert-Mignon A., Lord, Reginald V., Lord, Sarah J., Maule, Derek, Moss, Alan, Norton, Ian, Olver, Ian, Pavey, Darren, Raftopoulos, Spiro, Rajendra, Shan, Schoeman, Mark ... Yusoff, Ian F. (2015). Australian clinical practice guidelines for the diagnosis and management of Barrett's esophagus and early esophageal adenocarcinoma. Journal of Gastroenterology and Hepatology (Australia), 30 (5), 804-820. doi: 10.1111/jgh.12913

Australian clinical practice guidelines for the diagnosis and management of Barrett's esophagus and early esophageal adenocarcinoma

2015

Journal Article

Effect of resveratrol on experimental non-alcoholic steatohepatitis

Heeboll, Sara, Thomsen, Karen Louise, Clouston, Andrew, Sundelin, Elias Immanuel, Radko, Yulia, Christensen, Lars Porskjaer, Ramezani-Moghadam, Mehdi, Kreutzfeldt, Martin, Pedersen, Steen Bonlokke, Jessen, Niels, Hebbard, Lionel, George, Jacob and Gronbaek, Henning (2015). Effect of resveratrol on experimental non-alcoholic steatohepatitis. Pharmacological Research, 95-96, 34-41. doi: 10.1016/j.phrs.2015.03.005

Effect of resveratrol on experimental non-alcoholic steatohepatitis

2015

Journal Article

Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantation

Varelias, Antiopi, Gartlan, Kate H., Kreijveld, Ellen, Olver, Stuart D., Lor, Mary, Kuns, Rachel D., Lineburg, Katie E., Teal, Bianca E., Raffelt, Neil C., Cheong, Melody, Alexander, Kylie A., Koyama, Motoko, Markey, Kate A., Sturgeon, Elise, Leach, Justine, Reddy, Pavan, Kennedy, Glen A., Yanik, Gregory A., Blazar, Bruce R., Tey, Siok-Keen, Clouston, Andrew D., MacDonald, Kelli P. A., Cooke, Kenneth R. and Hill, Geoffrey R. (2015). Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantation. Blood, 125 (15), 2435-2444. doi: 10.1182/blood-2014-07-590232

Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantation

2015

Journal Article

Well-differentiated hepatocellular neoplasm of uncertain malignant potential-reply

Bedossa, Charles, Burt, Alastair D, Brunt, Elizabeth, Callea, Francesco, Clouston, Andrew D, Dienes, Hans Peter, Goodman, Zachary D, Gouw, Annette S. H, Hubscher, Stefan G, Roberts, Eve A, Roskams, Tania, Terracciano, Luigi, Tiniakos, Dina G, Torbenson, Michael S and Wanless, Ian R (2015). Well-differentiated hepatocellular neoplasm of uncertain malignant potential-reply. Human Pathology, 46 (4), 635-636. doi: 10.1016/j.humpath.2014.10.030

Well-differentiated hepatocellular neoplasm of uncertain malignant potential-reply

2015

Journal Article

Lack of efficacy of mTOR inhibitors and ACE pathway inhibitors as antifibrotic agents in evolving and established fibrosis in Mdr2-/- mice

Bridle, Kim R., Sobbe, Amy L., de Guzman, C. Erika, Santrampurwala, Nishreen, Jaskowski, Lesley A., Clouston, Andrew D., Campbell, Catherine M., Nathan Subramaniam, V. and Crawford, Darrell H. G. (2015). Lack of efficacy of mTOR inhibitors and ACE pathway inhibitors as antifibrotic agents in evolving and established fibrosis in Mdr2-/- mice. Liver International, 35 (4), 1451-1463. doi: 10.1111/liv.12494

Lack of efficacy of mTOR inhibitors and ACE pathway inhibitors as antifibrotic agents in evolving and established fibrosis in Mdr2-/- mice

2015

Journal Article

Inconsistent hepatic antifibrotic effects with the iron chelator deferasirox

Sobbe, Amy, Bridle, Kim R., Jaskowski, Lesley, de Guzman, C. Erika, Santrampurwala, Nishreen, Clouston, Andrew D., Campbell, Catherine M., Subramaniam, V. Nathan and Crawford, Darrell H. G. (2015). Inconsistent hepatic antifibrotic effects with the iron chelator deferasirox. Journal of Gastroenterology and Hepatology, 30 (3), 638-645. doi: 10.1111/jgh.12720

Inconsistent hepatic antifibrotic effects with the iron chelator deferasirox

2015

Journal Article

A clinicopathological and molecular analysis of 200 traditional serrated adenomas

Bettington, Mark L., Walker, Neal I., Rosty, Christophe, Brown, Ian S., Clouston, Andrew D., McKeone, Diane M., Pearson, Sally Ann, Klein, Kerenaftali, Leggett, Barbara A. and Whitehall, Vicki L. (2015). A clinicopathological and molecular analysis of 200 traditional serrated adenomas. Modern Pathology, 28 (3), 414-427. doi: 10.1038/modpathol.2014.122

A clinicopathological and molecular analysis of 200 traditional serrated adenomas

2015

Journal Article

Experimental hookworm infection and gluten microchallenge promote tolerance in celiac disease

Croese, John, Giacomin, Paul, Navarro, Severine, Clouston, Andrew, McCann, Leisa, Dougall, Annette, Ferreira, Ivana, Susianto, Atik, O'Rourke, Peter, Howlett, Mariko, McCarthy, James, Engwerda, Christian, Jones, Dianne and Loukas, Alex (2015). Experimental hookworm infection and gluten microchallenge promote tolerance in celiac disease. Journal of Allergy and Clinical Immunology, 135 (2), 508-516.e5. doi: 10.1016/j.jaci.2014.07.022

Experimental hookworm infection and gluten microchallenge promote tolerance in celiac disease

2015

Journal Article

Clonal expansion of hepatocytes with a selective advantage occurs during all stages of chronic hepatitis B virus infection

Tu, T, Mason, W.S, Clouston, A.D, Shackel, N.A, Mccaughan, G.W, Yeh, M.M, Schiff, E.R, Ruszkiewicz, A.R, Chen, J.W, Harley, H.A.J, Stroeher, U.H and Jilbert, A.R (2015). Clonal expansion of hepatocytes with a selective advantage occurs during all stages of chronic hepatitis B virus infection. Journal of Viral Hepatitis, 22 (9), 737-753. doi: 10.1111/jvh.12380

Clonal expansion of hepatocytes with a selective advantage occurs during all stages of chronic hepatitis B virus infection

2014

Journal Article

Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration

Irvine, Katharine M., Skoien, Richard, Bokil, Nilesh J., Melino, Michelle, Thomas, Gethin P., Loo, Dorothy, Gabrielli, Brian, Hill, Michelle M., Sweet, Matthew J., Clouston, Andrew D. and Powell, Elizabeth E. (2014). Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration. World Journal of Gastroenterology, 20 (47), 17851-17862. doi: 10.3748/wjg.v20.i47.17851

Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration

2014

Journal Article

Analysis of the intrahepatic ductular reaction and progenitor cell responses in hepatitis C virus recurrence after liver transplantation

Prakoso, Emilia, Tirnitz-Parker, Janina E. E., Clouston, Andrew D., Kayali, Zeid, Lee, Aimei, Gan, Eng K., Ramm, Grant A., Kench, James G., Bowen, David G., Olynyk, John K., McCaughan, Geoffrey W. and Shackel, Nicholas A. (2014). Analysis of the intrahepatic ductular reaction and progenitor cell responses in hepatitis C virus recurrence after liver transplantation. Liver Transplantation, 20 (12), 1508-1519. doi: 10.1002/lt.24007

Analysis of the intrahepatic ductular reaction and progenitor cell responses in hepatitis C virus recurrence after liver transplantation

2014

Journal Article

Non-alcoholic steatohepatitis weakens the acute phase response to endotoxin in rats

Thomsen, Karen L., Hebbard, Lionel, Glavind, Emilie, Clouston, Andrew, Vilstrup, Hendrik, George, Jacob and Gronbaek, Henning (2014). Non-alcoholic steatohepatitis weakens the acute phase response to endotoxin in rats. Liver International, 34 (10), 1584-1592. doi: 10.1111/liv.12547

Non-alcoholic steatohepatitis weakens the acute phase response to endotoxin in rats

2014

Journal Article

CSF-1-dependant donor-derived macrophages mediate chronic graft-versus-host disease

Alexander K.A., Flynn R., Lineburg K.E., Kuns R.D., Teal B.E., Olver S.D., Lor M., Raffelt N.C., Koyama M., Leveque L., Le Texier L., Melino M., Markey K.A., Varelias A., Engwerda C., Serody J.S., Janela B., Ginhoux F., Clouston A.D., Blazar B.R., Hill G.R. and MacDonald K.P.A. (2014). CSF-1-dependant donor-derived macrophages mediate chronic graft-versus-host disease. Journal of Clinical Investigation, 124 (10), 4266-4280. doi: 10.1172/JCI75935

CSF-1-dependant donor-derived macrophages mediate chronic graft-versus-host disease

2014

Journal Article

Experimental nonalcoholic steatohepatitis compromises ureagenesis, an essential hepatic metabolic function

Thomsen, Karen Louise, Gronbaek, Henning, Glavind, Emilie, Hebbard, Lionel, Jessen, Niels, Clouston, Andrew, George, Jacob and Vilstrup, Hendrik (2014). Experimental nonalcoholic steatohepatitis compromises ureagenesis, an essential hepatic metabolic function. American Journal of Physiology - Gastrointestinal and Liver Physiology, 307 (3), G295-G301. doi: 10.1152/ajpgi.00036.2014

Experimental nonalcoholic steatohepatitis compromises ureagenesis, an essential hepatic metabolic function