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2018

Journal Article

Immunomodulatory liposomes targeting liver macrophages arrest progression of nonalcoholic steatohepatitis

Maradana, Muralidhara Rao, Yekollu, Suman Kumar, Zeng, Bijun, Ellis, Jonathan, Clouston, Andrew, Miller, Gregory, Talekar, Meghna, Bhuyan, Zaied Ahmed, Mahadevaiah, Sachin, Powell, Elizabeth E., Irvine, Katharine M., Thomas, Ranjeny and O'Sullivan, Brendan John (2018). Immunomodulatory liposomes targeting liver macrophages arrest progression of nonalcoholic steatohepatitis. Metabolism: Clinical and Experimental, 78, 80-94. doi: 10.1016/j.metabol.2017.09.002

Immunomodulatory liposomes targeting liver macrophages arrest progression of nonalcoholic steatohepatitis

2018

Journal Article

Pathologic Features of Hereditary Cholestatic Diseases

Clouston, Andrew D. (2018). Pathologic Features of Hereditary Cholestatic Diseases. Surgical Pathology Clinics, 11 (2), 313-327. doi: 10.1016/j.path.2018.02.001

Pathologic Features of Hereditary Cholestatic Diseases

2017

Journal Article

Alcohol consumption in diabetic patients with nonalcoholic fatty liver disease

Patel, Preya J., Smith, David, Connor, Jason P., Horsfall, Leigh U., Hayward, Kelly L., Hossain, Fabrina, Williams, Suzanne, Johnson, Tracey, Stuart, Katherine A., Brown, Nigel N., Saad, Nivene, Clouston, Andrew D., Irvine, Katharine M., Russell, Anthony W., Valery, Patricia C. and Powell, Elizabeth E. (2017). Alcohol consumption in diabetic patients with nonalcoholic fatty liver disease. Canadian Journal of Gastroenterology and Hepatology, 2017 7927685, 7927685-8. doi: 10.1155/2017/7927685

Alcohol consumption in diabetic patients with nonalcoholic fatty liver disease

2017

Journal Article

A critical role for donor-derived IL-22 in cutaneous chronic GVHD

Gartlan, Kate H., Bommiasamy, Hemamalini, Paz, Katelyn, Wilkinson, Andrew N., Owen, Mary, Reichenbach, Dawn K., Banovic, Tatjana, Wehner, Kimberly, Buchanan, Faith, Varelias, Antiopi, Kuns, Rachel D., Chang, Karshing, Fedoriw, Yuri, Shea, Thomas, Coghill, James, Zaiken, Michael, Plank, Maximilian W., Foster, Paul S., Clouston, Andrew D., Blazar, Bruce R., Serody, Jonathan S. and Hill, Geoffrey R. (2017). A critical role for donor-derived IL-22 in cutaneous chronic GVHD. American Journal of Transplantation , 18 (4), 810-820. doi: 10.1111/ajt.14513

A critical role for donor-derived IL-22 in cutaneous chronic GVHD

2017

Journal Article

Multimorbidity and polypharmacy in diabetic patients with NAFLD: implications for disease severity and management

Patel, Preya Janubhai, Hayward, Kelly Lee, Rudra, Rathiga, Horsfall, Leigh Ula, Hossain, Fabrina, Williams, Suzanne, Johnson, Tracey, Brown, Nigel Neil, Saad, Nivene, Clouston, Andrew Donald, Stuart, Katherine Anne, Valery, Patricia Casarolli, Irvine, Katharine Margaret, Russell, Anthony William and Powell, Elizabeth Ellen (2017). Multimorbidity and polypharmacy in diabetic patients with NAFLD: implications for disease severity and management. Medicine, 96 (26) e6761, e6761. doi: 10.1097/MD.0000000000006761

Multimorbidity and polypharmacy in diabetic patients with NAFLD: implications for disease severity and management

2017

Journal Article

Eomesodermin promotes the development of Type-1 Regulatory T (TR1) cells

Zhang, Ping, Lee, Jason S., Gartlan, Kate H., Schuster, Iona S., Comerford, Iain, Varelias, Antiopi, Ullah, Md Ashik, Vuckovic, Slavica, Koyama, Motoko, Kuns, Rachel D., Locke, Kelly R., Beckett, Kirrilee J., Olver, Stuart D., Samson, Luke D., Montes de Oca, Marcela, de Labastida Rivera, Fabian, Clouston, Andrew D., Belz, Gabrielle T., Blazar, Bruce R., MacDonald, Kelli P., McColl, Shaun R., Thomas, Ranjeny, Engwerda, Christian R., Degli-Esposti, Mariapia A., Kallies, Axel, Tey, Siok-Keen and Hill, Geoffrey R. (2017). Eomesodermin promotes the development of Type-1 Regulatory T (TR1) cells. Science Immunology, 2 (10) eaah7152. doi: 10.1126/sciimmunol.aah7152

Eomesodermin promotes the development of Type-1 Regulatory T (TR1) cells

2017

Journal Article

Acute graft-versus-host disease is regulated by an IL-17-sensitive microbiome

Varelias, Antiopi, Ormerod, Kate L., Bunting, Mark D., Koyama, Motoko, Gartlan, Kate H., Kuns, Rachel D., Lachner, Nancy, Locke, Kelly R., Lim, Chun Y., Henden, Andrea S., Zhang, Ping, Clouston, Andrew D., Hasnain, Sumaira Z., McGuckin, Michael A., Blazar, Bruce R., MacDonald, Kelli P. A ., Hugenholtz, Philip and Hill, Geoffrey R. (2017). Acute graft-versus-host disease is regulated by an IL-17-sensitive microbiome. Blood, 129 (15), 2172-2185. doi: 10.1182/blood-2016-08-732628

Acute graft-versus-host disease is regulated by an IL-17-sensitive microbiome

2016

Journal Article

Clinicopathological and molecular features of sessile serrated adenomas with dysplasia or carcinoma

Bettington, Mark, Walker, Neal, Rosty, Christophe, Brown, Ian, Clouston, Andrew, McKeone, Diane, Pearson, Sally-Ann, Leggett, Barbara and Whitehall, Vicki (2016). Clinicopathological and molecular features of sessile serrated adenomas with dysplasia or carcinoma. Gut, 66 (1), 97-106. doi: 10.1136/gutjnl-2015-310456

Clinicopathological and molecular features of sessile serrated adenomas with dysplasia or carcinoma

2016

Journal Article

Multiplex serum protein analysis identifies novel biomarkers of advanced fibrosis in patients with chronic liver disease with the potential to improve diagnostic accuracy of established biomarkers

Irvine, Katharine M., Wockner, Leesa F., Hoffmann, Isabel, Horsfall, Leigh U., Fagan, Kevin J., Bijin, Veonice, Lee, Bernett, Clouston, Andrew D., Lampe, Guy, Connolly, John E. and Powell, Elizabeth E. (2016). Multiplex serum protein analysis identifies novel biomarkers of advanced fibrosis in patients with chronic liver disease with the potential to improve diagnostic accuracy of established biomarkers. PLoS ONE, 11 (11) 167001, e0167001. doi: 10.1371/journal.pone.0167001

Multiplex serum protein analysis identifies novel biomarkers of advanced fibrosis in patients with chronic liver disease with the potential to improve diagnostic accuracy of established biomarkers

2016

Journal Article

Identification of the CIMP-like subtype and aberrant methylation of members of the chromosomal segregation and spindle assembly pathways in esophageal adenocarcinoma

Krause, Lutz, Nones, Katia , Loffler, Kelly A., Nancarrow, Derek, Oey, Harald , Tang, Yue Hang, Wayte, Nicola J., Patch, Ann Marie, Patel, Kalpana , Brosda, Sandra, Manning, Suzanne, Lampe, Guy, Clouston, Andrew, Thomas, Janine, Stoye, Jens, Hussey, Damian J., Watson, David I., Lord, Reginald V., Phillips, Wayne A., Gotley, David, Smithers, B. Mark, Whiteman, David C., Hayward, Nicholas K., Grimmond, Sean M., Waddell, Nicola and Barbour, Andrew P. (2016). Identification of the CIMP-like subtype and aberrant methylation of members of the chromosomal segregation and spindle assembly pathways in esophageal adenocarcinoma. Carcinogenesis, 37 (4), 356-365. doi: 10.1093/carcin/bgw018

Identification of the CIMP-like subtype and aberrant methylation of members of the chromosomal segregation and spindle assembly pathways in esophageal adenocarcinoma

2016

Journal Article

Independent effects of diet and exercise training on fat oxidation in non-alcoholic fatty liver disease

Croci, Ilaria, Byrne, Nuala M., Chachay, Veronique S., Hills, Andrew P., Clouston, Andrew D., O’Moore-Sullivan, Trisha M., Prins, Johannes B., Macdonald, Graeme A. and Hickman, Ingrid J. (2016). Independent effects of diet and exercise training on fat oxidation in non-alcoholic fatty liver disease. World Journal of Hepatology, 8 (27), 1137-1148. doi: 10.4254/WJH.v8.i27.1137

Independent effects of diet and exercise training on fat oxidation in non-alcoholic fatty liver disease

2016

Journal Article

Corruption of dendritic cell antigen presentation during acute GVHD leads to regulatory T-cell failure and chronic GVHD

Leveque-El Mouttie, Lucie, Koyama, Motoko, Le Texier, Laetitia, Markey, Kate A., Cheong, Melody, Kuns, Rachel D., Lineburg, Katie E., Teal, Bianca E., Alexander, Kylie A., Clouston, Andrew D., Blazar, Bruce R., Hill, Geoffrey R. and MacDonald, Kelli P. A. (2016). Corruption of dendritic cell antigen presentation during acute GVHD leads to regulatory T-cell failure and chronic GVHD. Blood, 128 (6), 794-804. doi: 10.1182/blood-2015-11-680876

Corruption of dendritic cell antigen presentation during acute GVHD leads to regulatory T-cell failure and chronic GVHD

2016

Journal Article

Stereological analysis of liver biopsy histology sections as a reference standard for validating non-invasive liver fat fraction measurements by MRI

Pierre, Tim G. St., House, Michael J., Bangma, Sander J., Pang, Wenjie, Bathgate, Andrew, Gan, Eng K., Ayonrinde, Oyekoya T., Bhathal, Prithi S., Clouston, Andrew, Olynyk, John K. and Adams, Leon A. (2016). Stereological analysis of liver biopsy histology sections as a reference standard for validating non-invasive liver fat fraction measurements by MRI. PLoS ONE, 11 (8) e0160789, e0160789. doi: 10.1371/journal.pone.0160789

Stereological analysis of liver biopsy histology sections as a reference standard for validating non-invasive liver fat fraction measurements by MRI

2016

Journal Article

Point mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant

Li, Jun, Woods, Susan L., Healey, Sue, Beesley, Jonathan, Chen, Xiaoqing, Lee, Jason S., Sivakumaran, Haran, Wayte, Nicci, Nones, Katia, Waterfall, Joshua J., Pearson, John, Patch, Anne-Marie, Senz, Janine, Ferreira, Manuel A., Kaurah, Pardeep, Mackenzie, Robertson, Heravi-Moussavi, Alireza, Hansford, Samantha, Lannagan, Tamsin R. M., Spurdle, Amanda B., Simpson, Peter T., da Silva, Leonard, Lakhani, Sunil R., Clouston, Andrew D., Bettington, Mark, Grimpen, Florian, Busuttil, Rita A., Di Costanzo, Natasha, Boussioutas, Alex ... Chenevix-Trench, Georgia (2016). Point mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant. American Journal of Human Genetics, 98 (5), 830-842. doi: 10.1016/j.ajhg.2016.03.001

Point mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant

2016

Journal Article

Serrated tubulovillous adenoma of the large intestine

Bettington, Mark, Walker, Neal, Rosty, Christophe, Brown, Ian, Clouston, Andrew, Mckeone, Diane, Pearson, Sally-Ann, Klein, Kerenaftali, Leggett, Barbara and Whitehall, Vicki (2016). Serrated tubulovillous adenoma of the large intestine. Histopathology, 68 (4), 578-587. doi: 10.1111/his.12788

Serrated tubulovillous adenoma of the large intestine

2016

Journal Article

Spatiotemporal characterization of the cellular and molecular contributors to liver fibrosis in a murine hepatotoxic-injury model

Melino, Michelle, Gadd, Victoria L., Alexander, Kylie A., Beattie, Lynette, Lineburg, Katie E., Martinez, Michelle, Teal, Bianca, Le Texier, Laetitia, Irvine, Katharine M., Miller, Gregory C., Boyle, Glen M., Hill, Geoffrey R., Clouston, Andrew D., Powel, Elizabeth E. and MacDonald, Kelli P. A. (2016). Spatiotemporal characterization of the cellular and molecular contributors to liver fibrosis in a murine hepatotoxic-injury model. American Journal of Pathology, 186 (3), 524-538. doi: 10.1016/j.ajpath.2015.10.029

Spatiotemporal characterization of the cellular and molecular contributors to liver fibrosis in a murine hepatotoxic-injury model

2015

Journal Article

Aspartate aminotransferase to platelet ratio and fibrosis-4 as biomarkers in biopsy-validated pediatric cystic fibrosis liver disease

Leung, Daniel H., Khan, Mahjabeen, Minard, Charles G., Guffey, Danielle, Ramm, Louise E., Clouston, Andrew D., Miller, Gregory, Lewindon, Peter J., Shepherd, Ross W. and Ramm, Grant A. (2015). Aspartate aminotransferase to platelet ratio and fibrosis-4 as biomarkers in biopsy-validated pediatric cystic fibrosis liver disease. Hepatology, 62 (5), 1576-1583. doi: 10.1002/hep.28016

Aspartate aminotransferase to platelet ratio and fibrosis-4 as biomarkers in biopsy-validated pediatric cystic fibrosis liver disease

2015

Journal Article

Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury

Irvine, Katharine M., Clouston, Andrew D., Gadd, Victoria L., Miller, Gregory C., Wong, Weng-Yew, Melino, Michelle, Maradana, Muralidhara Rao, MacDonald, Kelli, Lang, Richard A., Sweet, Matthew J., Blumenthal, Antje and Powell, Elizabeth E. (2015). Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury. Fibrogenesis and Tissue Repair, 8 (19) 19, 19. doi: 10.1186/s13069-015-0036-7

Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury

2015

Journal Article

Effect of laparoscopic-assisted resection vs open resection on pathological outcomes in rectal cancer: the ALaCaRT randomized clinical trial

Stevenson, Andrew R. L., Solomon, Michael J., Lumley, John W., Hewett, Peter, Clouston, Andrew D., Gebski, Val J., Davies, Lucy, Wilson, Kate, Hague, Wendy and Simes, John (2015). Effect of laparoscopic-assisted resection vs open resection on pathological outcomes in rectal cancer: the ALaCaRT randomized clinical trial. JAMA - Journal of the American Medical Association, 314 (13), 1356-1363. doi: 10.1001/jama.2015.12009

Effect of laparoscopic-assisted resection vs open resection on pathological outcomes in rectal cancer: the ALaCaRT randomized clinical trial

2015

Journal Article

Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8<sup>+</sup> T cells that induce GVHD without antileukemic effects

Gartlan, Kate H., Markey, Kate A., Varelias, Antiopi, Bunting, Mark D., Koyama, Motoko, Kuns, Rachel D., Raffelt, Neil C., Olver, Stuart D., Lineburg, Katie E., Cheong, Melody, Teal, Bianca E., Lor, Mary, Comerford, Iain, Teng, Michele W. L., Smyth, Mark J., McCluskey, James, Rossjohn, Jamie, Stockinger, Brigitta, Boyle, Glen M., Lane, Steven W., Clouston, Andrew D., McColl, Shaun R., MacDonald, Kelli P. A. and Hill, Geoffrey R. (2015). Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8+ T cells that induce GVHD without antileukemic effects. Blood, 126 (13), 1609-1620. doi: 10.1182/blood-2015-01-622662

Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8<sup>+</sup> T cells that induce GVHD without antileukemic effects