2024 Journal Article Severe acute liver disease in adults: Contemporary role of histopathologyClouston, Andrew D, Gouw, Annette S H, Tiniakos, Dina, Bedossa, Pierre, Brunt, Elizabeth M, Callea, Francesco, Dienes, Hans-Peter, Goodman, Zachary D, Hubscher, Stefan G, Kakar, Sanjay, Kleiner, David E, Lackner, Carolin, Park, Young N, Roberts, Eve A, Schirmacher, Peter, Terracciano, Luigi, Torbenson, Michael, Wanless, Ian R, Zen, Yoh and Burt, Alastair D (2024). Severe acute liver disease in adults: Contemporary role of histopathology. Histopathology, 85 (4), 549-561. doi: 10.1111/his.15212 |
2024 Journal Article Calcineurin inhibition rescues alloantigen-specific central memory T cell subsets that promote chronic GVHDWang, Yewei, Ullah, Md Ashik, Waltner, Olivia G., Bhise, Shruti S., Ensbey, Kathleen S., Schmidt, Christine R., Legg, Samuel R.W., Sekiguchi, Tomoko, Nelson, Ethan L., Kuns, Rachel D., Nemychenkov, Nicole S., Atilla, Erden, Yeh, Albert C., Takahashi, Shuichiro, Boiko, Julie R., Varelias, Antiopi, Blazar, Bruce R., Koyama, Motoko, Minnie, Simone A., Clouston, Andrew D., Furlan, Scott N., Zhang, Ping and Hill, Geoffrey R. (2024). Calcineurin inhibition rescues alloantigen-specific central memory T cell subsets that promote chronic GVHD. Journal of Clinical Investigation, 134 (11) e170125, 19-19. doi: 10.1172/jci170125 |
2024 Journal Article Steatohepatitic hepatocellular Carcinoma:A new approach to classifying morphological subtypes of hepatocellular carcinomaSoon, Gwyneth S.T., Callea, Francesco, Burt, Alastair D., Cook, Sam, Terracciano, Luigi, Ercan, Caner, Dienes, Hans-Peter, Goodman, Zachary D., Roberts, Eve A., Clouston, Andrew D., Gouw, Annette S.H., Kleiner, David E., Park, Young Nyun, Chung, Taek, Schirmacher, Peter, Tiniakos, Dina, Dimopoulou, Konstantina, Weber, Achim, Endhardt, Katharina and Torbenson, Michael (2024). Steatohepatitic hepatocellular Carcinoma:A new approach to classifying morphological subtypes of hepatocellular carcinoma. Human Pathology, 149, 55-65. doi: 10.1016/j.humpath.2024.06.007 |
2024 Conference Publication qBallooning: AI-based ballooned hepatocyte detection and quantification by second harmonic generation/two photon excitation microscopyKleiner, David E., Clouston, Andrew D., Goodman, Zachary, Guy, Cynthia D., Brunt, Elizabeth M., Lackner, Carolin, Tiniakos, Dina G., Wee, Aileen, Yeh, Matthew, Leow, Wei Qiang, Chng, Elaine, Ren, Yayun, Goh, George Boon Bee, Powell, Elizabeth E., Rinella, Mary E., Sanyal, Arun J, Neuschwander-Tetri, Brent A., Younossi, Zobair, Charlton, Michael, Ratziu, Vlad, Harrison, Stephen A., Tai, Dean and Anstee, Quentin M. (2024). qBallooning: AI-based ballooned hepatocyte detection and quantification by second harmonic generation/two photon excitation microscopy. EASL Congress 2024, Milan, Italy, 5-8 June 2024. Amsterdam, Netherlands: Elsevier. doi: 10.1016/s0168-8278(24)01444-2 |
2024 Journal Article IL-6–mediated endothelial injury impairs antiviral humoral immunity after bone marrow transplantationZhang, Ping, Fleming, Peter, Andoniou, Christopher E., Waltner, Olivia G., Bhise, Shruti S., Martins, Jose Paulo, McEnroe, Benjamin A., Voigt, Valentina, Daly, Sheridan, Kuns, Rachel D., Ekwe, Adaeze P., Henden, Andrea S., Saldan, Alda, Olver, Stuart, Varelias, Antiopi, Smith, Corey, Schmidt, Christine R., Ensbey, Kathleen S., Legg, Samuel R.W., Sekiguchi, Tomoko, Minnie, Simone A., Gradwell, Mark, Wagenaar, Irma, Clouston, Andrew D., Koyama, Motoko, Furlan, Scott N., Kennedy, Glen A., Ward, E Sally, Degli-Esposti, Mariapia A. ... Tey, Siok-Keen (2024). IL-6–mediated endothelial injury impairs antiviral humoral immunity after bone marrow transplantation. Journal of Clinical Investigation, 134 (7) e174184. doi: 10.1172/jci174184 |
2024 Book Chapter Transplantation PathologyClouston, Andrew D. and Hübscher, Stefan G. (2024). Transplantation Pathology. MacSween's Pathology of the Liver, Eighth Edition. (pp. 947-1038) Amsterdam, Netherlands: Elsevier. doi: 10.1016/B978-0-7020-8228-3.00014-4 |
2023 Journal Article Intestinal microbiota controls graft-versus-host disease independent of donor-host genetic disparityKoyama, Motoko, Hippe, Daniel S., Srinivasan, Sujatha, Proll, Sean C., Miltiadous, Oriana, Li, Naisi, Zhang, Ping, Ensbey, Kathleen S., Hoffman, Noah G., Schmidt, Christine R., Yeh, Albert C., Minnie, Simone A., Strenk, Susan M., Fiedler, Tina L., Hattangady, Namita, Kowalsky, Jacob, Grady, Willian M., Degli-Esposti, Mariapia A., Varelias, Antiopi, Clouston, Andrew D., van den Brink, Marcel R.M., Dey, Neelendu, Randolph, Timothy W., Markey, Kate A., Fredricks, David N. and Hill, Geoffrey R. (2023). Intestinal microbiota controls graft-versus-host disease independent of donor-host genetic disparity. Immunity, 56 (8), 1876-1893.e8. doi: 10.1016/j.immuni.2023.06.024 |
2023 Journal Article Placental hepatic nodule with molecular subtypingYoung, Vanessa, Clouston, Andrew, Corbett-Burns, Sophie and Russell, Peter (2023). Placental hepatic nodule with molecular subtyping. International Journal of Surgical Pathology, 31 (5), 582-584. doi: 10.1177/10668969221117241 |
2023 Journal Article Patient-Reported Bowel, Urinary, and Sexual Outcomes After Laparoscopic-Assisted Resection or Open Resection for Rectal Cancer: The Australasian Laparoscopic Cancer of the Rectum Randomized Clinical Trial (ALaCart)Mercieca-Bebber, Rebecca, Eggins, Renee, Brown, Kilian, Gebski, Val J., Brewer, Kate, Lai, Lenna, Bailey, Lisa, Solomon, Michael J., Lumley, John W., Hewett, Peter, Clouston, Andrew D., Wilson, Kate, Hague, Wendy, Hayes, Julian, White, Stephen, Morgan, Matt, Simes, R. John and Stevenson, Andrew R. L. (2023). Patient-Reported Bowel, Urinary, and Sexual Outcomes After Laparoscopic-Assisted Resection or Open Resection for Rectal Cancer: The Australasian Laparoscopic Cancer of the Rectum Randomized Clinical Trial (ALaCart). Annals of Surgery, 277 (3), 449-455. doi: 10.1097/SLA.0000000000005412 |
2023 Journal Article Lithium attenuates graft-versus-host disease via effects on the intestinal stem cell nicheKoyama, Motoko, Samson, Luke, Ensbey, Kathleen S., Takahashi, Shuichiro, Clouston, Andrew D., Martin, Paul J. and Hill, Geoffrey R. (2023). Lithium attenuates graft-versus-host disease via effects on the intestinal stem cell niche. Blood, 141 (3), 315-319. doi: 10.1182/blood.2022015808 |
2023 Journal Article Phase Ib open-label, multicenter study of pixatimod, an activator of TLR9, in combination with nivolumab in subjects with microsatellite-stable metastatic colorectal cancer, metastatic pancreatic ductal adenocarcinoma and other solid tumorsLemech, Charlotte, Dredge, Keith, Bampton, Darryn, Hammond, Edward, Clouston, Andrew, Waterhouse, Nigel J, Stanley, Amanda C, Leveque-El Mouttie, Lucie, Chojnowski, Grace M, Haydon, Andrew, Pavlakis, Nick, Burge, Matthew, Brown, Michael P and Goldstein, David (2023). Phase Ib open-label, multicenter study of pixatimod, an activator of TLR9, in combination with nivolumab in subjects with microsatellite-stable metastatic colorectal cancer, metastatic pancreatic ductal adenocarcinoma and other solid tumors. Journal for ImmunoTherapy of Cancer, 11 (1) e006136, e006136. doi: 10.1136/jitc-2022-006136 |
2022 Journal Article Reliability of histologic assessment for NAFLD and development of an expanded NAFLD activity scorePai, Rish K., Jairath, Vipul, Hogan, Malcolm, Zou, Guangyong, Adeyi, Oyedele A., Anstee, Quentin M., Aqel, Bashar A., Behling, Cynthia, Carey, Elizabeth J., Clouston, Andrew D., Corey, Kathleen, Feagan, Brian G., Kleiner, David E., Ma, Christopher, McFarlane, Stefanie C., Noureddin, Mazen, Ratziu, Vlad, Valasek, Mark A., Younossi, Zobair M., Harrison, Stephen A. and Loomba, Rohit (2022). Reliability of histologic assessment for NAFLD and development of an expanded NAFLD activity score. Hepatology, 76 (4), 1150-1163. doi: 10.1002/hep.32475 |
2022 Journal Article Complexity of ballooned hepatocyte feature recognition: defining a training atlas for artificial intelligence-based imaging in NAFLDBrunt, Elizabeth M., Clouston, Andrew D., Goodman, Zachary, Guy, Cynthia, Kleiner, David E., Lackner, Carolin, Tiniakos, Dina G., Wee, Aileen, Yeh, Matthew, Leow, Wei Qiang, Chng, Elaine, Ren, Yayun, Boon Bee, George Goh, Powell, Elizabeth E., Rinella, Mary, Sanyal, Arun J., Neuschwander-Tetri, Brent, Younossi, Zobair, Charlton, Michael, Ratziu, Vlad, Harrison, Stephen A., Tai, Dean and Anstee, Quentin M. (2022). Complexity of ballooned hepatocyte feature recognition: defining a training atlas for artificial intelligence-based imaging in NAFLD. Journal of Hepatology, 76 (5), 1030-1041. doi: 10.1016/j.jhep.2022.01.011 |
2022 Journal Article Consensus recommendations for histological criteria of autoimmune hepatitis from the International AIH Pathology Group: results of a workshop on AIH histology hosted by the European Reference Network on Hepatological Diseases and the European Society of PathologyLohse, Ansgar W., Sebode, Marcial, Bhathal, Prithi S., Clouston, Andrew D., Dienes, Hans P., Jain, Dhanpat, Gouw, Annette S. H., Guindi, Maha, Kakar, Sanjay, Kleiner, David E., Krech, Till, Lackner, Carolin, Longerich, Thomas, Saxena, Romil, Terracciano, Luigi, Washington, Kay, Weidemann, Sören, Hübscher, Stefan G. and Tiniakos, Dina (2022). Consensus recommendations for histological criteria of autoimmune hepatitis from the International AIH Pathology Group: results of a workshop on AIH histology hosted by the European Reference Network on Hepatological Diseases and the European Society of Pathology. Liver International, 42 (5), 1058-1069. doi: 10.1111/liv.15217 |
2022 Journal Article Therapeutic potential of macrophage colony-stimulating factor (CSF1) in chronic liver diseaseKeshvari, Sahar, Genz, Berit, Teakle, Ngari, Caruso, Melanie, Cestari, Michelle F., Patkar, Omkar L., Tse, Brian W. C., Sokolowski, Kamil A., Ebersbach, Hilmar, Jascur, Julia, MacDonald, Kelli P. A., Miller, Gregory, Ramm, Grant A., Pettit, Allison R., Clouston, Andrew D., Powell, Elizabeth E., Hume, David A. and Irvine, Katharine M. (2022). Therapeutic potential of macrophage colony-stimulating factor (CSF1) in chronic liver disease. Disease Models and Mechanisms, 15 (4) dmm049387, 1-15. doi: 10.1242/dmm.049387 |
2022 Journal Article ROCK2 inhibition attenuates profibrogenic immune cell function to reverse thioacetamide-induced liver fibrosisNalkurthi, Christina, Schroder, Wayne A., Melino, Michelle, Irvine, Katharine M., Nyuydzefe, Melanie, Chen, Wei, Liu, Jing, Teng, Michele WL., Hill, Geoffrey R., Bertolino, Patrick, Blazar, Bruce R., Miller, Gregory C., Clouston, Andrew D., Zanin-Zhorov, Alexandra and MacDonald, Kelli PA. (2022). ROCK2 inhibition attenuates profibrogenic immune cell function to reverse thioacetamide-induced liver fibrosis. JHEP Reports, 4 (1) 100386, 1-14. doi: 10.1016/j.jhepr.2021.100386 |
2021 Journal Article Bone marrow regulatory T cells are a unique population, supported by niche-specific cytokines and plasmacytoid dendritic cells, and required for chronic graft-versus-host disease controlNicholls, Jemma, Cao, Benjamin, Le Texier, Laetitia, Xiong, Laura Yan, Hunter, Christopher R., Llanes, Genesis, Aguliar, Ethan G., Schroder, Wayne A., Phipps, Simon, Lynch, Jason P., Cao, Huimin, Heazlewood, Shen Y., Williams, Brenda, Clouston, Andrew D., Nefzger, Christian M., Polo, Jose M., Nilsson, Susan K., Blazar, Bruce R. and MacDonald, Kelli P. A. (2021). Bone marrow regulatory T cells are a unique population, supported by niche-specific cytokines and plasmacytoid dendritic cells, and required for chronic graft-versus-host disease control. Frontiers in Cell and Developmental Biology, 9 737880, 737880. doi: 10.3389/fcell.2021.737880 |
2021 Journal Article IFN-λ therapy prevents severe gastrointestinal graft-versus-host diseaseHenden, Andrea S., Koyama, Motoko, Robb, Renee J., Forero, Adriana, Kuns, Rachel D., Chang, Karshing, Ensbey, Kathleen S., Varelias, Antiopi, Kazakoff, Stephen H., Waddell, Nicole, Clouston, Andrew D., Giri, Rabina, Begun, Jakob, Blazar, Bruce R., Degli-Esposti, Mariapia A., Kotenko, Sergei V., Lane, Steven W., Bowerman, Kate L., Savan, Ram, Hugenholtz, Philip, Gartlan, Kate H. and Hill, Geoffrey R. (2021). IFN-λ therapy prevents severe gastrointestinal graft-versus-host disease. Blood, 138 (8), 722-737. doi: 10.1182/blood.2020006375 |
2021 Conference Publication Interferon Lambda Protects Gastrointestinal Stem Cells from Acute GvhdHenden, Andrea S., Robb, Renee, Forero, Adriana, Kuns, Rachel D., Ensbey, Kathleen S., Chang, Karshing, Varelias, Antiopi, Kazakoff, Stephen H., Waddell, Nic, Clouston, Andrew D., Giri, Rabina, Begun, Jakob, Blazar, Bruce R., Degli-Esposti, Mariapia A., Kotenko, Sergei V., Lane, Steven W., Bowerman, Kate L., Savan, Ram, Hugenholtz, Philip, Gartlan, Kate H. and Hill, Geoffrey (2021). Interferon Lambda Protects Gastrointestinal Stem Cells from Acute Gvhd. 2021 TCT Meetings of ASTCT and CIBMTR, Online, 8-12 February 2021. Amsterdam, Netherlands: Elsevier. doi: 10.1016/s2666-6367(21)00107-x |
2020 Journal Article Randomized, placebo controlled trial of experimental hookworm infection for improving gluten tolerance in celiac diseaseCroese, John, Miller, Gregory C., Marquart, Louise, Llewellyn, Stacey, Gupta, Rohit, Becker, Luke, Clouston, Andrew D., Welch, Christine, Sidorenko, Julia, Wallace, Leanne, Visscher, Peter M., Remedios, Matthew L., McCarthy, James S., OʼRourke, Peter, Radford-Smith, Graham, Loukas, Alex, Norrie, Mark, Masson, John W., Gearry, Richard B., Rahman, Tony and Giacomin, Paul R. (2020). Randomized, placebo controlled trial of experimental hookworm infection for improving gluten tolerance in celiac disease. Clinical and Translational Gastroenterology, 11 (12) e00274, 1-11. doi: 10.14309/ctg.0000000000000274 |