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2022 Journal Article Therapeutic potential of macrophage colony-stimulating factor (CSF1) in chronic liver diseaseKeshvari, Sahar, Genz, Berit, Teakle, Ngari, Caruso, Melanie, Cestari, Michelle F., Patkar, Omkar L., Tse, Brian W. C., Sokolowski, Kamil A., Ebersbach, Hilmar, Jascur, Julia, MacDonald, Kelli P. A., Miller, Gregory, Ramm, Grant A., Pettit, Allison R., Clouston, Andrew D., Powell, Elizabeth E., Hume, David A. and Irvine, Katharine M. (2022). Therapeutic potential of macrophage colony-stimulating factor (CSF1) in chronic liver disease. Disease Models and Mechanisms, 15 (4) dmm049387, 1-15. doi: 10.1242/dmm.049387 |
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2022 Journal Article ROCK2 inhibition attenuates profibrogenic immune cell function to reverse thioacetamide-induced liver fibrosisNalkurthi, Christina, Schroder, Wayne A., Melino, Michelle, Irvine, Katharine M., Nyuydzefe, Melanie, Chen, Wei, Liu, Jing, Teng, Michele WL., Hill, Geoffrey R., Bertolino, Patrick, Blazar, Bruce R., Miller, Gregory C., Clouston, Andrew D., Zanin-Zhorov, Alexandra and MacDonald, Kelli PA. (2022). ROCK2 inhibition attenuates profibrogenic immune cell function to reverse thioacetamide-induced liver fibrosis. JHEP Reports, 4 (1) 100386, 1-14. doi: 10.1016/j.jhepr.2021.100386 |
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2021 Journal Article ROR1 and ROR2 expression in pancreatic cancerLiu, Dongli, Sharbeen, George, Phillips, Phoebe, Johns, Amber L., Gill, Anthony J., Chantrill, Lorraine A., Timpson, Paul, Chou, Angela, Pajic, Marina, Dwarte, Tanya, Herrmann, David, Vennin, Claire, Cox, Thomas R., Pereira, Brooke, Ritchie, Shona, Reed, Daniel A., Chambers, Cecilia R., Metcalf, Xanthe, Nobis, Max, Waddell, Nicola, Pearson, John V., Patch, Ann-Marie, Nones, Katia, Newell, Felicity, Mukhopadhyay, Pamela, Addala, Venkateswar, Kazakoff, Stephen, Holmes, Oliver, Leonard, Conrad ... Ford, Caroline E. (2021). ROR1 and ROR2 expression in pancreatic cancer. BMC Cancer, 21 (1) 1199. doi: 10.1186/s12885-021-08952-9 |
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2021 Journal Article DNA methylation patterns identify subgroups of pancreatic neuroendocrine tumors with clinical associationLakis, Vanessa, Lawlor, Rita T., Newell, Felicity, Patch, Ann-Marie, Mafficini, Andrea, Sadanandam, Anguraj, Koufariotis, Lambros T., Johnston, Rebecca L., Leonard, Conrad, Wood, Scott, Rusev, Borislav, Corbo, Vincenzo, Luchini, Claudio, Cingarlini, Sara, Landoni, Luca, Salvia, Roberto, Milella, Michele, Chang, David, Bailey, Peter, Jamieson, Nigel B., Duthie, Fraser, Gingras, Marie-Claude, Muzny, Donna M., Wheeler, David A., Gibbs, Richard A., Milione, Massimo, Chantrill, Lorraine A., Timpson, Paul, Chou, Angela ... Scarpa, Aldo (2021). DNA methylation patterns identify subgroups of pancreatic neuroendocrine tumors with clinical association. Communications Biology, 4 (1) 155, 1-11. doi: 10.1038/s42003-020-01469-0 |
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2021 Journal Article Bone marrow regulatory T cells are a unique population, supported by niche-specific cytokines and plasmacytoid dendritic cells, and required for chronic graft-versus-host disease controlNicholls, Jemma, Cao, Benjamin, Le Texier, Laetitia, Xiong, Laura Yan, Hunter, Christopher R., Llanes, Genesis, Aguliar, Ethan G., Schroder, Wayne A., Phipps, Simon, Lynch, Jason P., Cao, Huimin, Heazlewood, Shen Y., Williams, Brenda, Clouston, Andrew D., Nefzger, Christian M., Polo, Jose M., Nilsson, Susan K., Blazar, Bruce R. and MacDonald, Kelli P. A. (2021). Bone marrow regulatory T cells are a unique population, supported by niche-specific cytokines and plasmacytoid dendritic cells, and required for chronic graft-versus-host disease control. Frontiers in Cell and Developmental Biology, 9 737880, 737880. doi: 10.3389/fcell.2021.737880 |
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2021 Journal Article IFN-λ therapy prevents severe gastrointestinal graft-versus-host diseaseHenden, Andrea S., Koyama, Motoko, Robb, Renee J., Forero, Adriana, Kuns, Rachel D., Chang, Karshing, Ensbey, Kathleen S., Varelias, Antiopi, Kazakoff, Stephen H., Waddell, Nicole, Clouston, Andrew D., Giri, Rabina, Begun, Jakob, Blazar, Bruce R., Degli-Esposti, Mariapia A., Kotenko, Sergei V., Lane, Steven W., Bowerman, Kate L., Savan, Ram, Hugenholtz, Philip, Gartlan, Kate H. and Hill, Geoffrey R. (2021). IFN-λ therapy prevents severe gastrointestinal graft-versus-host disease. Blood, 138 (8), 722-737. doi: 10.1182/blood.2020006375 |
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2021 Conference Publication Interferon Lambda Protects Gastrointestinal Stem Cells from Acute GvhdHenden, Andrea S., Robb, Renee, Forero, Adriana, Kuns, Rachel D., Ensbey, Kathleen S., Chang, Karshing, Varelias, Antiopi, Kazakoff, Stephen H., Waddell, Nic, Clouston, Andrew D., Giri, Rabina, Begun, Jakob, Blazar, Bruce R., Degli-Esposti, Mariapia A., Kotenko, Sergei V., Lane, Steven W., Bowerman, Kate L., Savan, Ram, Hugenholtz, Philip, Gartlan, Kate H. and Hill, Geoffrey (2021). Interferon Lambda Protects Gastrointestinal Stem Cells from Acute Gvhd. 2021 TCT Meetings of ASTCT and CIBMTR, Online, 8-12 February 2021. Amsterdam, Netherlands: Elsevier. doi: 10.1016/s2666-6367(21)00107-x |
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2021 Journal Article Targeting DNA damage response and replication stress in pancreatic cancerDreyer, Stephan B., Upstill-Goddard, Rosie, Paulus-Hock, Viola, Paris, Clara, Lampraki, Eirini-Maria, Dray, Eloise, Serrels, Bryan, Caligiuri, Giuseppina, Rebus, Selma, Plenker, Dennis, Galluzzo, Zachary, Brunton, Holly, Cunningham, Richard, Tesson, Mathias, Nourse, Craig, Bailey, Ulla-Maja, Jones, Marc D., Moran-Jones, Kim, Wright, Derek W., Duthie, Fraser, Oien, Karin, Evers, Lisa, McKay, Colin J., McGregor, Grant A., Gulati, Aditi, Brough, Rachel, Bajrami, Ilirjana, Pettitt, Stephan, Dziubinski, Michele L. ... Sansom, Owen J. (2021). Targeting DNA damage response and replication stress in pancreatic cancer. Gastroenterology, 160 (1), 362-377.e13. doi: 10.1053/j.gastro.2020.09.043 |
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2020 Journal Article Randomized, placebo controlled trial of experimental hookworm infection for improving gluten tolerance in celiac diseaseCroese, John, Miller, Gregory C., Marquart, Louise, Llewellyn, Stacey, Gupta, Rohit, Becker, Luke, Clouston, Andrew D., Welch, Christine, Sidorenko, Julia, Wallace, Leanne, Visscher, Peter M., Remedios, Matthew L., McCarthy, James S., OʼRourke, Peter, Radford-Smith, Graham, Loukas, Alex, Norrie, Mark, Masson, John W., Gearry, Richard B., Rahman, Tony and Giacomin, Paul R. (2020). Randomized, placebo controlled trial of experimental hookworm infection for improving gluten tolerance in celiac disease. Clinical and Translational Gastroenterology, 11 (12) e00274, 1-11. doi: 10.14309/ctg.0000000000000274 |
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2020 Journal Article Longitudinal change in simple scores identifies fibrosis status in people with nonalcoholic fatty liver diseaseMcKillen, Benjamin J., Powell, Elizabeth E., Horsfall, Leigh U., Clouston, Andrew D., Brown, Nigel N., Elangovan, Harendran, Patel, Preya J., Valery, Patricia C., Irvine, Katharine M., Bernard, Anne and Hayward, Kelly L. (2020). Longitudinal change in simple scores identifies fibrosis status in people with nonalcoholic fatty liver disease. Journal of Clinical Gastroenterology, 54 (7), 661-662. doi: 10.1097/MCG.0000000000001372 |
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2020 Journal Article Fifty years of impact on liver pathology: a history of the GnomesTorbenson, Michael, Desmet, Valeer, Denk, Helmut, Callea, Francesco, Burt, Alastair D., Hübscher, Stefan G., Terracciano, Luigi, Dienes, Hans-Peter, Goodman, Zachary D., Bedossa, Pierre, Wanless, Ian R., Roberts, Eve A., Brunt, Elizabeth M., Clouston, Andrew D., Gouw, Annette S.H., Kleiner, David, Schirmacher, Peter and Tiniakos, Dina (2020). Fifty years of impact on liver pathology: a history of the Gnomes. Virchows Archiv, 478 (2), 191-200. doi: 10.1007/s00428-020-02879-5 |
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2020 Journal Article ASS1 overexpression: a hallmark of sonic hedgehog hepatocellular adenomas; recommendations for clinical practiceSala, Margaux, Gonzales, Delphine, Leste-Lasserre, Thierry, Dugot-Senant, Nathalie, Paradis, Valerie, Di Tommaso, Sylvaine, Dupuy, Jean-William, Pitard, Vincent, Dourthe, Cyril, Sciarra, Amedeo, Sempoux, Christine, Ferrell, Linda D., Clouston, Andrew D., Miller, Gregory, Yeh, Mathew M., Thung, Swan, Gouw, Annette S. H., Quaglia, Alberto, Han, Jing, Huan, Ji, Fan, Cathy, Crawford, James, Nakanuma, Yasuni, Harada, Kenichi, le Bail, Brigitte, Castain, Claire, Frulio, Nora, Trillaud, Herve, Possenti, Laurent ... Saltel, Frederic (2020). ASS1 overexpression: a hallmark of sonic hedgehog hepatocellular adenomas; recommendations for clinical practice. Hepatology Communications, 4 (6), 809-824. doi: 10.1002/hep4.1514 |
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2020 Journal Article Large size and haemorrhage are not contraindications to laparoscopic resection of hepatocellular adenomaMcKay, Bartholomew, Webber, Laurence, Manoharan, Bavahuna, Miller, Gregory, Clouston, Andrew, Bryant, Richard, Cavallucci, David and O'Rourke, Nicholas (2020). Large size and haemorrhage are not contraindications to laparoscopic resection of hepatocellular adenoma. ANZ Journal of Surgery, 90 (6), 1099-1103. doi: 10.1111/ans.15702 |
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2020 Conference Publication Diverse IL-6 signalling modalities drive pathogenic T cell differentiation and graft-versus-host-disease after allotransplantationGartlan, Kate H., Wilkinson, Andrew, Chang, Karshing, Kuns, Rachel D., Henden, Andrea, Minnie, Simone A., Ensbey, Kathleen S., Clouston, Andrew, Zhang, Ping, Koyama, Motoko, Hidalgo, Juan, Rose-John, Stefan, Varelias, Antiopi, Vuckovic, Slavica and Hill, Geoffrey R. (2020). Diverse IL-6 signalling modalities drive pathogenic T cell differentiation and graft-versus-host-disease after allotransplantation. Immunology 2020™ Meeting, Honolulu, HI United States, 8 - 12 May 2020. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.204.supp.87.33 |
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2020 Journal Article Adult onset of genetic disorders in bile acid transport in the liverMiller, Gregory C. and Clouston, Andrew D. (2020). Adult onset of genetic disorders in bile acid transport in the liver. Human Pathology, 96, 2-7. doi: 10.1016/j.humpath.2019.10.006 |
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2020 Journal Article Evaluation of the histological variability of core and wedge biopsies in nonalcoholic fatty liver disease in bariatric surgical patientsOoi, Geraldine J., Clouston, Andrew, Johari, Yazmin, Kemp, William W., Roberts, Stuart K., Brown, Wendy A. and Burton, Paul R. (2020). Evaluation of the histological variability of core and wedge biopsies in nonalcoholic fatty liver disease in bariatric surgical patients. Surgical Endoscopy, 35 (3), 1210-1218. doi: 10.1007/s00464-020-07490-y |
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2019 Journal Article Myeloid cell deletion of Aryl hydrocarbon Receptor Nuclear Translocator (ARNT) induces non-alcoholic steatohepatitisScott, Christopher, Stokes, Rebecca, Cha, Kuan Minn, Clouston, Andrew, Eslam, Mohammed, Metwally, Mayda, Swarbrick, Michael M., George, Jacob and Gunton, Jenny E. (2019). Myeloid cell deletion of Aryl hydrocarbon Receptor Nuclear Translocator (ARNT) induces non-alcoholic steatohepatitis. PLoS One, 14 (12) e0225332, 1-20. doi: 10.1371/journal.pone.0225332 |
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2019 Journal Article MHC class II antigen presentation by the intestinal epithelium initiates graft-versus-host disease and is influenced by the microbiotaKoyama, Motoko, Mukhopadhyay, Pamela, Schuster, Iona S., Henden, Andrea S., Hülsdünker, Jan, Varelias, Antiopi, Vetizou, Marie, Kuns, Rachel D., Robb, Renee J., Zhang, Ping, Blazar, Bruce B., Thomas, Ranjeny, Begun, Jakob, Waddell, Nicola, Trinchieri, Giorgio, Zeiser, Robert, Clouston, Andrew D., Degli-Esposti, Mariapia A. and Hill, Geoffrey R. (2019). MHC class II antigen presentation by the intestinal epithelium initiates graft-versus-host disease and is influenced by the microbiota. Immunity, 51 (5), 885-898. doi: 10.1016/j.immuni.2019.08.011 |
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2019 Journal Article Standardising the interpretation of liver biopsies in non-alcoholic fatty liver disease clinical trialsPai, Rish K., Kleiner, David E., Hart, John, Adeyi, Oyedele A., Clouston, Andrew D., Behling, Cynthia A., Jain, Dhanpat, Kakar, Sanjay, Brahmania, Mayur, Burgart, Lawrence, Batts, Kenneth P., Valasek, Mark A., Torbenson, Michael S., Guindi, Maha, Wang, Hanlin L., Ajmera, Veeral, Adams, Leon A., Parker, Claire E., Feagan, Brian G., Loomba, Rohit and Jairath, Vipul (2019). Standardising the interpretation of liver biopsies in non-alcoholic fatty liver disease clinical trials. Alimentary Pharmacology and Therapeutics, 50 (10), 1100-1111. doi: 10.1111/apt.15503 |
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2019 Journal Article Regression of fibrosis stage with treatment reduces long-term risk of liver cancer in patients with hemochromatosis caused by mutation in HFEBardou-Jacquet, Edouard, Morandeau, Emilie, Anderson, Gregory J., Ramm, Grant A., Ramm, Louise E., Morcet, Jeff, Bouzille, Guillaume, Dixon, Jeannette, Clouston, Andrew D., Lainé, Fabrice, Turlin, Bruno, Powell, Lawrie W. and Deugnier, Yves M. (2019). Regression of fibrosis stage with treatment reduces long-term risk of liver cancer in patients with hemochromatosis caused by mutation in HFE. Clinical Gastroenterology and Hepatology, 18 (8), 1851-1857. doi: 10.1016/j.cgh.2019.10.010 |
