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2020

Journal Article

Longitudinal change in simple scores identifies fibrosis status in people with nonalcoholic fatty liver disease

McKillen, Benjamin J., Powell, Elizabeth E., Horsfall, Leigh U., Clouston, Andrew D., Brown, Nigel N., Elangovan, Harendran, Patel, Preya J., Valery, Patricia C., Irvine, Katharine M., Bernard, Anne and Hayward, Kelly L. (2020). Longitudinal change in simple scores identifies fibrosis status in people with nonalcoholic fatty liver disease. Journal of Clinical Gastroenterology, 54 (7), 661-662. doi: 10.1097/MCG.0000000000001372

Longitudinal change in simple scores identifies fibrosis status in people with nonalcoholic fatty liver disease

2020

Journal Article

Fifty years of impact on liver pathology: a history of the Gnomes

Torbenson, Michael, Desmet, Valeer, Denk, Helmut, Callea, Francesco, Burt, Alastair D., Hübscher, Stefan G., Terracciano, Luigi, Dienes, Hans-Peter, Goodman, Zachary D., Bedossa, Pierre, Wanless, Ian R., Roberts, Eve A., Brunt, Elizabeth M., Clouston, Andrew D., Gouw, Annette S.H., Kleiner, David, Schirmacher, Peter and Tiniakos, Dina (2020). Fifty years of impact on liver pathology: a history of the Gnomes. Virchows Archiv, 478 (2), 191-200. doi: 10.1007/s00428-020-02879-5

Fifty years of impact on liver pathology: a history of the Gnomes

2020

Journal Article

ASS1 overexpression: a hallmark of sonic hedgehog hepatocellular adenomas; recommendations for clinical practice

Sala, Margaux, Gonzales, Delphine, Leste-Lasserre, Thierry, Dugot-Senant, Nathalie, Paradis, Valerie, Di Tommaso, Sylvaine, Dupuy, Jean-William, Pitard, Vincent, Dourthe, Cyril, Sciarra, Amedeo, Sempoux, Christine, Ferrell, Linda D., Clouston, Andrew D., Miller, Gregory, Yeh, Mathew M., Thung, Swan, Gouw, Annette S. H., Quaglia, Alberto, Han, Jing, Huan, Ji, Fan, Cathy, Crawford, James, Nakanuma, Yasuni, Harada, Kenichi, le Bail, Brigitte, Castain, Claire, Frulio, Nora, Trillaud, Herve, Possenti, Laurent ... Saltel, Frederic (2020). ASS1 overexpression: a hallmark of sonic hedgehog hepatocellular adenomas; recommendations for clinical practice. Hepatology Communications, 4 (6), 809-824. doi: 10.1002/hep4.1514

ASS1 overexpression: a hallmark of sonic hedgehog hepatocellular adenomas; recommendations for clinical practice

2020

Journal Article

Large size and haemorrhage are not contraindications to laparoscopic resection of hepatocellular adenoma

McKay, Bartholomew, Webber, Laurence, Manoharan, Bavahuna, Miller, Gregory, Clouston, Andrew, Bryant, Richard, Cavallucci, David and O'Rourke, Nicholas (2020). Large size and haemorrhage are not contraindications to laparoscopic resection of hepatocellular adenoma. ANZ Journal of Surgery, 90 (6), 1099-1103. doi: 10.1111/ans.15702

Large size and haemorrhage are not contraindications to laparoscopic resection of hepatocellular adenoma

2020

Conference Publication

Diverse IL-6 signalling modalities drive pathogenic T cell differentiation and graft-versus-host-disease after allotransplantation

Gartlan, Kate H., Wilkinson, Andrew, Chang, Karshing, Kuns, Rachel D., Henden, Andrea, Minnie, Simone A., Ensbey, Kathleen S., Clouston, Andrew, Zhang, Ping, Koyama, Motoko, Hidalgo, Juan, Rose-John, Stefan, Varelias, Antiopi, Vuckovic, Slavica and Hill, Geoffrey R. (2020). Diverse IL-6 signalling modalities drive pathogenic T cell differentiation and graft-versus-host-disease after allotransplantation. Immunology 2020™ Meeting, Honolulu, HI United States, 8 - 12 May 2020. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.204.supp.87.33

Diverse IL-6 signalling modalities drive pathogenic T cell differentiation and graft-versus-host-disease after allotransplantation

2020

Journal Article

Adult onset of genetic disorders in bile acid transport in the liver

Miller, Gregory C. and Clouston, Andrew D. (2020). Adult onset of genetic disorders in bile acid transport in the liver. Human Pathology, 96, 2-7. doi: 10.1016/j.humpath.2019.10.006

Adult onset of genetic disorders in bile acid transport in the liver

2020

Journal Article

Evaluation of the histological variability of core and wedge biopsies in nonalcoholic fatty liver disease in bariatric surgical patients

Ooi, Geraldine J., Clouston, Andrew, Johari, Yazmin, Kemp, William W., Roberts, Stuart K., Brown, Wendy A. and Burton, Paul R. (2020). Evaluation of the histological variability of core and wedge biopsies in nonalcoholic fatty liver disease in bariatric surgical patients. Surgical Endoscopy, 35 (3), 1210-1218. doi: 10.1007/s00464-020-07490-y

Evaluation of the histological variability of core and wedge biopsies in nonalcoholic fatty liver disease in bariatric surgical patients

2019

Journal Article

Myeloid cell deletion of Aryl hydrocarbon Receptor Nuclear Translocator (ARNT) induces non-alcoholic steatohepatitis

Scott, Christopher, Stokes, Rebecca, Cha, Kuan Minn, Clouston, Andrew, Eslam, Mohammed, Metwally, Mayda, Swarbrick, Michael M., George, Jacob and Gunton, Jenny E. (2019). Myeloid cell deletion of Aryl hydrocarbon Receptor Nuclear Translocator (ARNT) induces non-alcoholic steatohepatitis. Plos One, 14 (12) ARTN e0225332, e0225332. doi: 10.1371/journal.pone.0225332

Myeloid cell deletion of Aryl hydrocarbon Receptor Nuclear Translocator (ARNT) induces non-alcoholic steatohepatitis

2019

Journal Article

MHC class II antigen presentation by the intestinal epithelium initiates graft-versus-host disease and is influenced by the microbiota

Koyama, Motoko, Mukhopadhyay, Pamela, Schuster, Iona S., Henden, Andrea S., Hülsdünker, Jan, Varelias, Antiopi, Vetizou, Marie, Kuns, Rachel D., Robb, Renee J., Zhang, Ping, Blazar, Bruce B., Thomas, Ranjeny, Begun, Jakob, Waddell, Nicola, Trinchieri, Giorgio, Zeiser, Robert, Clouston, Andrew D., Degli-Esposti, Mariapia A. and Hill, Geoffrey R. (2019). MHC class II antigen presentation by the intestinal epithelium initiates graft-versus-host disease and is influenced by the microbiota. Immunity, 51 (5), 885-898. doi: 10.1016/j.immuni.2019.08.011

MHC class II antigen presentation by the intestinal epithelium initiates graft-versus-host disease and is influenced by the microbiota

2019

Journal Article

Standardising the interpretation of liver biopsies in non-alcoholic fatty liver disease clinical trials

Pai, Rish K., Kleiner, David E., Hart, John, Adeyi, Oyedele A., Clouston, Andrew D., Behling, Cynthia A., Jain, Dhanpat, Kakar, Sanjay, Brahmania, Mayur, Burgart, Lawrence, Batts, Kenneth P., Valasek, Mark A., Torbenson, Michael S., Guindi, Maha, Wang, Hanlin L., Ajmera, Veeral, Adams, Leon A., Parker, Claire E., Feagan, Brian G., Loomba, Rohit and Jairath, Vipul (2019). Standardising the interpretation of liver biopsies in non-alcoholic fatty liver disease clinical trials. Alimentary Pharmacology and Therapeutics, 50 (10), 1100-1111. doi: 10.1111/apt.15503

Standardising the interpretation of liver biopsies in non-alcoholic fatty liver disease clinical trials

2019

Journal Article

Regression of fibrosis stage with treatment reduces long-term risk of liver cancer in patients with hemochromatosis caused by mutation in HFE

Bardou-Jacquet, Edouard, Morandeau, Emilie, Anderson, Gregory J., Ramm, Grant A., Ramm, Louise E., Morcet, Jeff, Bouzille, Guillaume, Dixon, Jeannette, Clouston, Andrew D., Lainé, Fabrice, Turlin, Bruno, Powell, Lawrie W. and Deugnier, Yves M. (2019). Regression of fibrosis stage with treatment reduces long-term risk of liver cancer in patients with hemochromatosis caused by mutation in HFE. Clinical Gastroenterology and Hepatology, 18 (8), 1851-1857. doi: 10.1016/j.cgh.2019.10.010

Regression of fibrosis stage with treatment reduces long-term risk of liver cancer in patients with hemochromatosis caused by mutation in HFE

2019

Journal Article

Donor T-cell–derived GM-CSF drives alloantigen presentation by dendritic cells in the gastrointestinal tract

Gartlan, Kate H., Koyama, Motoko, Lineburg, Katie E., Chang, Karshing, Ensbey, Kathleen S., Kuns, Rachel D., Henden, Andrea S., Samson, Luke D., Clouston, Andrew D., Lopez, Angel F., MacDonald, Kelli P. A. and Hill, Geoffrey R. (2019). Donor T-cell–derived GM-CSF drives alloantigen presentation by dendritic cells in the gastrointestinal tract. Blood Advances, 3 (19), 2859-2865. doi: 10.1182/bloodadvances.2019000053

Donor T-cell–derived GM-CSF drives alloantigen presentation by dendritic cells in the gastrointestinal tract

2019

Journal Article

IL-6 dysregulation originates in dendritic cells and initiates graft-versus-host disease via classical signaling

Wilkinson, Andrew N., Chang, Karshing, Kuns, Rachel D., Henden, Andrea S., Minnie, Simone A., Ensbey, Kathleen S., Clouston, Andrew D., Zhang, Ping, Koyama, Motoko, Hidalgo, Juan, Rose-John, Stefan, Varelias, Antiopi, Vuckovic, Slavica, Gartlan, Kate H. and Hill, Geoffrey R. (2019). IL-6 dysregulation originates in dendritic cells and initiates graft-versus-host disease via classical signaling. Blood, 134 (23), 2092-2106. doi: 10.1182/blood.2019000396

IL-6 dysregulation originates in dendritic cells and initiates graft-versus-host disease via classical signaling

2019

Conference Publication

A time-dependent analysis of Non-alcoholic Fatty Liver Disease (NAFLD) Fibrosis Score and Fibrosis-4 score in patients with NAFLD

McKillen, B., Elangovan, H., Horsfall, L., Patel, P., Hayward, K., Clouston, A., Radford-Smith, D., Valery, P., Britton, L., Brown, N., Bernard, A. and Powell, E. (2019). A time-dependent analysis of Non-alcoholic Fatty Liver Disease (NAFLD) Fibrosis Score and Fibrosis-4 score in patients with NAFLD. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) “The Universe Within”, Adelaide, SA Australia, 8–10 September 2019. Richmond, VIC Australia: Wiley-Blackwell.

A time-dependent analysis of Non-alcoholic Fatty Liver Disease (NAFLD) Fibrosis Score and Fibrosis-4 score in patients with NAFLD

2019

Journal Article

Clinically significant fibrosis is associated with longitudinal increases in fibrosis-4 and nonalcoholic fatty liver disease fibrosis scores

Janubhai Patel, Preya, Chieh-Yu Cheng, Johnson, Banh, Xuan, Gracen, Lucy, Radford-Smith, Daniel, Hossain, Fabrina, Horsfall, Leigh Ula, Lee Hayward, Kelly, Williams, Suzanne, Johnson, Tracey, Brown, Nigel Neil, Saad, Nivene, Stuart, Katherine Anne, Russell, Anthony William, Valery, Patricia Casarolli, Clouston, Andrew Donald, Irvine, Katharine Margaret, Bernard, Anne and Powell, Elizabeth Ellen (2019). Clinically significant fibrosis is associated with longitudinal increases in fibrosis-4 and nonalcoholic fatty liver disease fibrosis scores. Clinical Gastroenterology and Hepatology, 18 (3), 710-718.e4. doi: 10.1016/j.cgh.2019.07.036

Clinically significant fibrosis is associated with longitudinal increases in fibrosis-4 and nonalcoholic fatty liver disease fibrosis scores

2019

Journal Article

Inhibitors of class I histone deacetylases attenuate thioacetamide-induced liver fibrosis in mice by suppressing hepatic Type 2 inflammation

Loh, Zhixuan, Fitzsimmons, Rebecca L., Reid, Robert C., Ramnath, Divya, Clouston, Andrew, Gupta, Praveer K., Irvine, Katharine M., Powell, Elizabeth E., Schroder, Kate, Stow, Jennifer L., Sweet, Matthew J., Fairlie, David P. and Iyer, Abishek (2019). Inhibitors of class I histone deacetylases attenuate thioacetamide-induced liver fibrosis in mice by suppressing hepatic Type 2 inflammation. British Journal of Pharmacology, 176 (19) bph.14768, 3775-3790. doi: 10.1111/bph.14768

Inhibitors of class I histone deacetylases attenuate thioacetamide-induced liver fibrosis in mice by suppressing hepatic Type 2 inflammation

2019

Conference Publication

Immune responses to the microbiome tune MHC class II antigen presentation by the intestinal epithelium to control gut pathology

Koyama, Motoko, Mukhopadhyay, Pamela, Schuster, Iona S., Henden, Andrea S., Hülsdünker, Jan, Varelias, Antiopi, Vetizou, Marie, Kuns, Rachel D., Robb, Renee J., Zhang, Ping, Blazar, Bruce R., Thomas, Ranjeny, Begun, Jakob, Waddell, Nicola, Trinchieri, Giorgio, Zeiser, Robert, Clouston, Andrew D., Degli-Esposti, Mariapia A. and Hill, Geoffrey R. (2019). Immune responses to the microbiome tune MHC class II antigen presentation by the intestinal epithelium to control gut pathology. Immunology 2019™ Meeting, San Diego, CA United States, 9-13 May 2019. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.202.supp.69.38

Immune responses to the microbiome tune MHC class II antigen presentation by the intestinal epithelium to control gut pathology

2019

Journal Article

Disease-free Survival and Local Recurrence After Laparoscopic-assisted Resection or Open Resection for Rectal Cancer: The Australasian Laparoscopic Cancer of the Rectum Randomized Clinical Trial

Stevenson, Andrew R. L., Solomon, Michael J., Brown, Christopher S. B., Lumley, John W., Hewett, Peter, Clouston, Andrew D., Gebski, Val J., Wilson, Kate, Hague, Wendy, Simes, John, on behalf of the Australasian Gastro-Intestinal Trials Group (AGITG) ALaCaRT investigators and Clark, David (2019). Disease-free Survival and Local Recurrence After Laparoscopic-assisted Resection or Open Resection for Rectal Cancer: The Australasian Laparoscopic Cancer of the Rectum Randomized Clinical Trial. Annals of Surgery, 269 (4), 596-602. doi: 10.1097/SLA.0000000000003021

Disease-free Survival and Local Recurrence After Laparoscopic-assisted Resection or Open Resection for Rectal Cancer: The Australasian Laparoscopic Cancer of the Rectum Randomized Clinical Trial

2019

Conference Publication

Histone Deacetylase Inhibitors Attenuate Hepatic Fibrosis through Suppression of Group 2 Innate Lymphoid Cells and Type 2 Inflammation

Iyer, Abishek, Loh, Zhixuan, Fitzsimmons, Rebecca L., Reid, Robert C., Ramnath, Divya, Clouston, Andrew, Irvine, Katharine M., Powell, Elizabeth E., Schroder, Kate, Stow, Jennifer L., Sweet, Matthew J. and Fairlie, David P. (2019). Histone Deacetylase Inhibitors Attenuate Hepatic Fibrosis through Suppression of Group 2 Innate Lymphoid Cells and Type 2 Inflammation. Experimental Biology Meeting (EB), Orlando Fl, Apr 06-09, 2019. HOBOKEN: WILEY.

Histone Deacetylase Inhibitors Attenuate Hepatic Fibrosis through Suppression of Group 2 Innate Lymphoid Cells and Type 2 Inflammation

2019

Conference Publication

Endoscopically resected colorectal polyps ≤10 mm are not always innocuous: caution against a routine discard policy

Boyd, Grace, Clouston, Andrew, Miller, Gregory, Bettington, Mark, Rosty, Christophe and Brown, Ian (2019). Endoscopically resected colorectal polyps ≤10 mm are not always innocuous: caution against a routine discard policy. Pathology Update 2019, Melbourne, VIC Australia, 22-24 February 2019. Elsevier. doi: 10.1016/j.pathol.2018.12.176

Endoscopically resected colorectal polyps ≤10 mm are not always innocuous: caution against a routine discard policy