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2017 Journal Article Eomesodermin promotes the development of Type-1 Regulatory T (TR1) cellsZhang, Ping, Lee, Jason S., Gartlan, Kate H., Schuster, Iona S., Comerford, Iain, Varelias, Antiopi, Ullah, Md Ashik, Vuckovic, Slavica, Koyama, Motoko, Kuns, Rachel D., Locke, Kelly R., Beckett, Kirrilee J., Olver, Stuart D., Samson, Luke D., Montes de Oca, Marcela, de Labastida Rivera, Fabian, Clouston, Andrew D., Belz, Gabrielle T., Blazar, Bruce R., MacDonald, Kelli P., McColl, Shaun R., Thomas, Ranjeny, Engwerda, Christian R., Degli-Esposti, Mariapia A., Kallies, Axel, Tey, Siok-Keen and Hill, Geoffrey R. (2017). Eomesodermin promotes the development of Type-1 Regulatory T (TR1) cells. Science Immunology, 2 (10) eaah7152. doi: 10.1126/sciimmunol.aah7152 |
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2017 Journal Article Latitude gradient influences the age of onset of rheumatoid arthritis: a worldwide surveyRamos-Remus, Cesar, Barajas-Ochoa, Aldo, Ramirez-Gomez, Andrea, Castillo-Ortiz, Jose D., Brambila-Barba, Victor, Adebajo, Adewale O., Espinoza, Luis R., Aceves-Avila, Francisco J., Sanchez-Gonzalez, Jorge M., Boudersa, Nadia, Slimani, Samy, Ladjouze-Rezig, Aicha, Diaz, Monica P., Kirmayr, Karin I., Asnal, Cecilia A., Catoggio, Luis J., Citera, Gustavo, Casado, Gustavo C., Alvarez, Analia P., Pisoni, Cecilia N., Benavente, Emilio, Lopez-Cabanillas, Adriana, Baez, Roberto M., Pons-Estel, Bernardo A., Sacnun, Monica P., Cavallasca, Javier A., Paniego, Raul H., Proudman, Susanna M., Thomas, Ranjeny ... Villegas-Morales, Sol (2017). Latitude gradient influences the age of onset of rheumatoid arthritis: a worldwide survey. Clinical Rheumatology, 36 (3), 485-497. doi: 10.1007/s10067-016-3481-9 |
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2017 Journal Article Genetic association of ankylosing spondylitis with TBX21 influences T-bet and pro-inflammatory cytokine expression in humans and SKG mice as a model of spondyloarthritisLau, Max C., Keith, Patricia, Costello, Mary-Ellen, Bradbury, Linda A., Hollis, Kelly A., Thomas, Ranjeny, Thomas, Gethin P., Brown, Matthew A. and Kenna, Tony J. (2017). Genetic association of ankylosing spondylitis with TBX21 influences T-bet and pro-inflammatory cytokine expression in humans and SKG mice as a model of spondyloarthritis. Annals of the Rheumatic Diseases, 76 (1), 261-269. doi: 10.1136/annrheumdis-2015-208677 |
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2016 Journal Article Treatment with dexamethasone and monophosphoryl lipid a removes disease-associated transcriptional signatures in monocyte-derived dendritic cells from rheumatoid arthritis patients and confers tolerogenic featuresGarcia-Gonzalez, Paulina A., Schinnerling, Katina, Sepulveda-Gutierrez, Alejandro, Maggi, Jaxaira, Hoyos, Lorena, Morales, Rodrigo A., Mehdi, Ahmed M., Nel, Hendrik J., Soto, Lilian, Pesce, Barbara, Carmen Molina, Maria, Cuchacovich, Miguel, Larrondo, Milton L., Neira, Oscar, Francisco Catalan, Diego, Hilkens, Catharien M., Thomas, Ranjeny, Verdugo, Ricardo A. and Aguillon, Juan C. (2016). Treatment with dexamethasone and monophosphoryl lipid a removes disease-associated transcriptional signatures in monocyte-derived dendritic cells from rheumatoid arthritis patients and confers tolerogenic features. Frontiers in Immunology, 7 (OCT) 458, 458. doi: 10.3389/fimmu.2016.00458 |
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2016 Journal Article Development and performance evaluation of novel nanoparticles of a grafted copolymer loaded with curcuminMutalik, Srinivas, Suthar, Neelam A., Managuli, Renuka S., Shetty, Pallavi K., Avadhani, Kiran, Kalthur, Guruprasad, Kulkarni, Raghavendra V. and Thomas, Ranjeny (2016). Development and performance evaluation of novel nanoparticles of a grafted copolymer loaded with curcumin. International Journal of Biological Macromolecules, 86, 709-720. doi: 10.1016/j.ijbiomac.2015.11.092 |
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2016 Journal Article Antigen-encoding bone marrow terminates islet-directed memory CD8+ T-cell responses to alleviate islet transplant rejectionColeman, Miranda A., Jessup, Claire F., Bridge, Jennifer A., Overgaard, Nana H., Penko, Daniella, Walters, Stacey, Borg, Danielle J., Galea, Ryan, Forbes, Josephine M., Thomas, Ranjeny, Coates, Patrick T. C., Grey, Shane T., Wells, James W. and Steptoe, Raymond J. (2016). Antigen-encoding bone marrow terminates islet-directed memory CD8+ T-cell responses to alleviate islet transplant rejection. Diabetes, 65 (5), 1328-1340. doi: 10.2337/db15-1418 |
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2016 Journal Article Reduced interleukin-2 responsiveness impairs the ability of Treg cells to compete for IL-2 in nonobese diabetic miceJames, Cini R., Buckle, Irina, Muscate, Franziska, Otsuka, Masayuki, Nakao, Mari, Oon, Jack S. H., Steptoe, Raymond J., Thomas, Ranjeny and Hamilton-Williams, Emma E. (2016). Reduced interleukin-2 responsiveness impairs the ability of Treg cells to compete for IL-2 in nonobese diabetic mice. Immunology and Cell Biology, 94 (5), 509-519. doi: 10.1038/icb.2016.7 |
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2015 Journal Article Safety and retention of combination triple disease-modifying anti-rheumatic drugs in new-onset rheumatoid arthritisCummins, L., Katikireddi, V. S., Shankaranarayana, S., Su, K. Y. C., Duggan, E., Videm, V., Pahau, H. and Thomas, R. (2015). Safety and retention of combination triple disease-modifying anti-rheumatic drugs in new-onset rheumatoid arthritis. Internal Medicine Journal, 45 (12), 1266-1273. doi: 10.1111/imj.12896 |
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2015 Journal Article Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetesPang, Dimeng, Irvine, Katharine M., Mehdi, Ahmed M., Thomas, Helen E., Harris, Mark, Hamilton-Williams, Emma E. and Thomas, Ranjeny (2015). Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetes. Clinical and Translational Immunology, 4 (8) e41, e41.1-e41.9. doi: 10.1038/cti.2015.17 |
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2015 Journal Article Coeliac disease and rheumatoid arthritis: similar mechanisms, different antigensKoning, Frits, Thomas, Ranjeny, Rossjohn, Jamie and Toes, Rene E. (2015). Coeliac disease and rheumatoid arthritis: similar mechanisms, different antigens. Nature Reviews Rheumatology, 11 (8), 450-461. doi: 10.1038/nrrheum.2015.59 |
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2015 Journal Article IL-6 driven STAT signalling in circulating CD4+ lymphocytes is a marker for early anti-citrullinated peptide antibody-negative rheumatoid arthritis.Anderson, Amy E., Pratt, Arthur G., Sedhom, Mamdouh A. K., Doran, John Paul, Routledge, Christine, Hargreaves, Ben, Brown, Philip M., Cao, Kim-Anh Le, Isaacs, John D. and Thomas, Ranjeny (2015). IL-6 driven STAT signalling in circulating CD4+ lymphocytes is a marker for early anti-citrullinated peptide antibody-negative rheumatoid arthritis.. Annals of the Rheumatic Diseases, 75 (2), 466-473. doi: 10.1136/annrheumdis-2014-205850 |
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2015 Journal Article Role of genetics in infection-associated arthritisBenham, Helen, Robinson, Philip C., Baillet, Athan C., Rehaume, Linda M. and Thomas, Ranjeny (2015). Role of genetics in infection-associated arthritis. Best Practice and Research: Clinical Rheumatology, 29 (2), 213-225. doi: 10.1016/j.berh.2015.02.002 |
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2014 Journal Article Current smoking is a risk factor for incident ankylosing spondylitis – HUNT population-based Norwegian health study.Videm, Vibeke, Cortes, Adrian, Thomas, Ranjeny and Brown, Matthew A. (2014). Current smoking is a risk factor for incident ankylosing spondylitis – HUNT population-based Norwegian health study.. Journal of Rheumatology, 41 (10), 2041-2048. doi: 10.3899/jrheum.140353 |
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2014 Journal Article Cardiovascular disease is increased prior to onset of rheumatoid arthritis but not osteoarthritis: the population-based Nord-Trøndelag health study (HUNT)Pahau, Helen, Brown, Matthew A., Paul, Sanjoy, Thomas, Ranjeny and Videm, Vibeke (2014). Cardiovascular disease is increased prior to onset of rheumatoid arthritis but not osteoarthritis: the population-based Nord-Trøndelag health study (HUNT). Arthritis Research and Therapy, 16 (2) R85, 1-9. doi: 10.1186/ar4527 |
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2014 Journal Article Immunogenic, but not steady-state, antigen presentation permits regulatory T-cells to control CD8+T-cell effector differentiation by IL-2 modulationMcNally, Alice, McNally, Michael, Galea, Ryan, Thomas, Ranjeny and Steptoe, Raymond J. (2014). Immunogenic, but not steady-state, antigen presentation permits regulatory T-cells to control CD8+T-cell effector differentiation by IL-2 modulation. PloS One, 9 (1) e85455, e85455. doi: 10.1371/journal.pone.0085455 |
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2014 Journal Article Dendritic cells as targets or therapeutics in rheumatic autoimmune diseaseThomas, Ranjeny (2014). Dendritic cells as targets or therapeutics in rheumatic autoimmune disease. Current Opinion in Rheumatology, 26 (2), 211-218. doi: 10.1097/BOR.0000000000000032 |
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2014 Journal Article Identification of Self-antigen-specific T Cells Reflecting Loss of Tolerance in Autoimmune Disease Underpins Preventative Immunotherapeutic Strategies in Rheumatoid ArthritisLaw, Soi-Chen, Benham, Helen, Reid, Hugh H., Rossjohn, Jamie and Thomas, Ranjeny (2014). Identification of Self-antigen-specific T Cells Reflecting Loss of Tolerance in Autoimmune Disease Underpins Preventative Immunotherapeutic Strategies in Rheumatoid Arthritis. Rheumatic Disease Clinics of North America, 40 (4), 735-752. doi: 10.1016/j.rdc.2014.07.015 |
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2013 Journal Article Receptor-specific delivery of protein antigen to dendritic cells by a nanoemulsion formed using top-down non-covalent click self-assemblyZeng, B. J., Chuan, Y. P., O’Sullivan, B., Caminschi, I., Lahoud, M. H., Thomas, R. and Middelberg, A. P. J. (2013). Receptor-specific delivery of protein antigen to dendritic cells by a nanoemulsion formed using top-down non-covalent click self-assembly. Small, 9 (22), 3736-3742. doi: 10.1002/smll.201300078 |
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2013 Journal Article RelB, AhR and dendritic cells RelB and the aryl hydrocarbon receptor: dendritic cell tolerance at the epithelial interfaceThomas, Ranjeny (2013). RelB, AhR and dendritic cells RelB and the aryl hydrocarbon receptor: dendritic cell tolerance at the epithelial interface. Immunology and Cell Biology, 91 (9), 543-544. doi: 10.1038/icb.2013.51 |
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2013 Journal Article Th17 and Th22 cells in psoriatic arthritis and psoriasisBenham, Helen, Norris, Paul, Goodall, Jane, Wechalekar, Mihir D., FitzGerald, Oliver, Szentpetery, Agnes, Smith, Malcolm, Thomas, Ranjeny and Gaston, Hill (2013). Th17 and Th22 cells in psoriatic arthritis and psoriasis. Arthritis Research and Therapy, 15 (5) R136. doi: 10.1186/ar4317 |
