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2013 Journal Article Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacyColeman, Miranda A., Bridge, Jennifer A., Lane, Steven W., Dixon, Chantelle M., Hill, Geoffrey R., Wells, James W., Thomas, Ranjeny and Steptoe, Raymond J. (2013). Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacy. Blood, 121 (6), 1049-1058. doi: 10.1182/blood-2012-06-434100 |
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2013 Journal Article Synovial fluid CD1c(+) myeloid dendritic cells - the inflammatory picture emergesThomas, Ranjeny (2013). Synovial fluid CD1c(+) myeloid dendritic cells - the inflammatory picture emerges. Arthritis Research & Therapy, 15 (6) 128. doi: 10.1186/ar4420 |
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2013 Journal Article Trajectory of intensive treat-to-target disease modifying drug regimen in an observational study of an early rheumatoid arthritis cohortWhite, Douglas, Pahau, Helen, Duggan, Emily, Paul, Sanjoy and Thomas, Ranjeny (2013). Trajectory of intensive treat-to-target disease modifying drug regimen in an observational study of an early rheumatoid arthritis cohort. BMJ Open, 3 (7) e003083, e003083.1-e003083.10. doi: 10.1136/bmjopen-2013-003083 |
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2013 Journal Article Targeted delivery of curcumin for treating type 2 diabetesMaradana, Muralidhara Rao, Thomas, Ranjeny and O'Sullivan, Brendan J. (2013). Targeted delivery of curcumin for treating type 2 diabetes. Molecular Nutrition and Food Research, 57 (9), 1550-1556. doi: 10.1002/mnfr.201200791 |
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2013 Journal Article Dendritic cells and the promise of antigen-specific therapy in rheumatoid arthritisThomas, Ranjeny (2013). Dendritic cells and the promise of antigen-specific therapy in rheumatoid arthritis. Arthritis Research & Therapy, 15 (1) 204, 204.1-204.10. doi: 10.1186/ar4130 |
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2012 Journal Article T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope allelesLaw, Soi Cheng, Street, Shayna, Yu, Chien-Hsiung Alan, Capini, Christelle, Ramnoruth, Sakoontalla, Nel, Hendrik J., van Gorp, Eline, Hyde, Claire, Lau, Kim, Pahau, Helen, Purcell, Anthony W. and Thomas, Ranjeny (2012). T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles. Arthritis Research and Therapy, 14 (3) R118, R118.1-R118.12. doi: 10.1186/ar3848 |
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2012 Journal Article Enrichment of circulating IL-17-secreting IL-23 receptor-positive gamma-delta T cells in patients with active ankylosing spondylitisKenna, Tony J., Davidson, Stuart I., Duan, Ran, Bradbury, Linda A., McFarlane, Janelle, Smith, Malcolm, Weedon, Helen, Street, Shayna, Thomas, Ranjeny, Thomas, Gethin P. and Brown, Matthew A. (2012). Enrichment of circulating IL-17-secreting IL-23 receptor-positive gamma-delta T cells in patients with active ankylosing spondylitis. Arthritis and Rheumatism, 64 (5), 1420-1429. doi: 10.1002/art.33507 |
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2012 Journal Article Peripheral blood monocyte gene expression profile clinically stratifies patients with recent-onset type 1 diabetesIrvine, Katharine M., Gallego, Patricia, An, Xiaoyu, Best, Shannon E., Thomas, Gethin, Wells, Christine, Harris, Mark, Cotterill, Andrew and Thomas, Ranjeny (2012). Peripheral blood monocyte gene expression profile clinically stratifies patients with recent-onset type 1 diabetes. Diabetes, 61 (5), 1281-1290. doi: 10.2337/db11-1549 |
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2012 Journal Article Autoimmunity: innovation in pathogenesis and therapyThomas, Ranjeny (2012). Autoimmunity: innovation in pathogenesis and therapy. Immunology and Cell Biology, 90 (3), 255-255. doi: 10.1038/icb.2012.5 |
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2012 Journal Article T-cell receptor signaling and the pathogenesis of autoimmune arthritis: insights from mouse and manSakaguchi, Shimon, Benham, Helen, Cope, Andrew P. and Thomas, Ranjeny (2012). T-cell receptor signaling and the pathogenesis of autoimmune arthritis: insights from mouse and man. Immunology and Cell Biology, 90 (3), 277-287. doi: 10.1038/icb.2012.4 |
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2012 Journal Article Co-delivery of antigen and a lipophilic anti-inflammatory drug to cells via a tailorable nanocarrier emulsionChuan, Yap Pang, Zeng, Bi Yun, O'Sullivan, Brendan, Thomas, Ranjeny and Middelberg, Anton P. J. (2012). Co-delivery of antigen and a lipophilic anti-inflammatory drug to cells via a tailorable nanocarrier emulsion. Journal of Colloid and Interface Science, 368 (1), 616-624. doi: 10.1016/j.jcis.2011.11.014 |
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2011 Journal Article Targeting curcusomes to inflammatory dendritic cells inhibits NF-{kappa}b and improves insulin resistance in obese miceYekollu, Suman Kumar, Thomas, Ranjeny and O'Sullivan, Brendan (2011). Targeting curcusomes to inflammatory dendritic cells inhibits NF-{kappa}b and improves insulin resistance in obese mice. Diabetes, 60 (11), 2928-2938. doi: 10.2337/db11-0275 |
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2011 Journal Article Langerhans cells are precommitted to immune tolerance inductionShklovskaya, Elena, O'Sullivan, Brendan J., Ng, Lai Guan, Roediger, Ben, Thomas, Ranjeny, Weninger, Wolfgang and de St Groth, Barbara Fazekas (2011). Langerhans cells are precommitted to immune tolerance induction. Proceedings of the National Academy of Sciences of the United States of America, 108 (44), 18049-18054. doi: 10.1073/pnas.1110076108 |
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2011 Journal Article Immunotherapy with costimulatory dendritic cells to control autoimmune inflammationO'Sullivan, Brendan J., Pai, Saparna, Street, Shayna, An, Xiayou, Macdonald, Kelli P. A., Wong, Michelle, Strutton, Geoffrey, Gerondakis, Steve, Steptoe, Raymond J., Fazekas de St Groth, Barbara, Hill, Geoffrey R. and Thomas, Ranjeny (2011). Immunotherapy with costimulatory dendritic cells to control autoimmune inflammation. Journal of Immunology, 187 (7), 4018-4030. doi: 10.4049/jimmunol.1101727 |
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2011 Journal Article CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasisMcNally, Alice, Hill, Geoffrey R., Sparwasser, Tim, Thomas, Ranjeny and Steptoe, Raymond J. (2011). CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis. Proceedings of the National Academy of Sciences of the United States of America, 108 (18), 7529-7534. doi: 10.1073/pnas.1103782108 |
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2011 Journal Article Reduced soluble receptor for advanced glycation end-products in COPDSmith, D. J., Yerkovich, S. T., Towers, M. A., Carroll, M. L., Thomas, R. and Upham, J. W. (2011). Reduced soluble receptor for advanced glycation end-products in COPD. European Respiratory Journal, 37 (3), 516-522. doi: 10.1183/09031936.00029310 |
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2011 Journal Article Streptococcus pneumoniae infection suppresses allergic airways disease by inducing regulatory T-cellsPreston, J. A., Thorburn, A. N., Starkey, M. R., Beckett, E. L., Horvat, J. C., Wade, M. A., O'Sullivan, B. J., Thomas, R., Beagley, K. W., Gibson, P. G., Foster, P. S. and Hansbro, P. M. (2011). Streptococcus pneumoniae infection suppresses allergic airways disease by inducing regulatory T-cells. European Respiratory Journal, 37 (1), 53-64. doi: 10.1183/09031936.00049510 |
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2011 Journal Article Interleukin-1 beta produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T-cells: Implications for the timing of tolerizing immunotherapyBertin-Maghit, Sebastien, Pang, Dimeng, O'Sullivan, Brendan, Best, Shannon, Duggan, Emily, Paul, Sanjoy, Thomas, Helen, Kay, Thomas W. H., Harrison, Leonard C., Steptoe, Raymond and Thomas, Ranjeny (2011). Interleukin-1 beta produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T-cells: Implications for the timing of tolerizing immunotherapy. Diabetes, 60 (1), 248-257. doi: 10.2337/db10-0104 |
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2010 Journal Article Pneumococcal conjugate vaccine-induced regulatory T cells suppress the development of allergic airways diseaseThorburn, Alison N., O'Sullivan, Brendan J., Thomas, Ranjeny, Kumar, Rakesh K., Foster, Peter S., Gibson, Peter G. and Hansbro, Philip M. (2010). Pneumococcal conjugate vaccine-induced regulatory T cells suppress the development of allergic airways disease. Thorax, 65 (12), 1053-1060. doi: 10.1136/thx.2009.131508 |
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2010 Journal Article IL-1 signalling determines the fate of skin grafts expressing non-self protein in keratinocytesHadis, Usriansyah, Leggatt, Graham R., Thomas, Ranjeny, Frazer, Ian H. and Kovacs, Eva M. (2010). IL-1 signalling determines the fate of skin grafts expressing non-self protein in keratinocytes. Experimental Dermatology, 19 (8), 723-729. doi: 10.1111/j.1600-0625.2010.01092.x |
