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2012

Journal Article

T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles

Law, Soi Cheng, Street, Shayna, Yu, Chien-Hsiung Alan, Capini, Christelle, Ramnoruth, Sakoontalla, Nel, Hendrik J., van Gorp, Eline, Hyde, Claire, Lau, Kim, Pahau, Helen, Purcell, Anthony W. and Thomas, Ranjeny (2012). T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles. Arthritis Research and Therapy, 14 (3) R118, R118.1-R118.12. doi: 10.1186/ar3848

T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles

2012

Journal Article

Autoimmunity: innovation in pathogenesis and therapy

Thomas, Ranjeny (2012). Autoimmunity: innovation in pathogenesis and therapy. Immunology and Cell Biology, 90 (3), 255-255. doi: 10.1038/icb.2012.5

Autoimmunity: innovation in pathogenesis and therapy

2012

Journal Article

T-cell receptor signaling and the pathogenesis of autoimmune arthritis: insights from mouse and man

Sakaguchi, Shimon, Benham, Helen, Cope, Andrew P. and Thomas, Ranjeny (2012). T-cell receptor signaling and the pathogenesis of autoimmune arthritis: insights from mouse and man. Immunology and Cell Biology, 90 (3), 277-287. doi: 10.1038/icb.2012.4

T-cell receptor signaling and the pathogenesis of autoimmune arthritis: insights from mouse and man

2012

Journal Article

Co-delivery of antigen and a lipophilic anti-inflammatory drug to cells via a tailorable nanocarrier emulsion

Chuan, Yap Pang, Zeng, Bi Yun, O'Sullivan, Brendan, Thomas, Ranjeny and Middelberg, Anton P. J. (2012). Co-delivery of antigen and a lipophilic anti-inflammatory drug to cells via a tailorable nanocarrier emulsion. Journal of Colloid and Interface Science, 368 (1), 616-624. doi: 10.1016/j.jcis.2011.11.014

Co-delivery of antigen and a lipophilic anti-inflammatory drug to cells via a tailorable nanocarrier emulsion

2011

Journal Article

Langerhans cells are precommitted to immune tolerance induction

Shklovskaya, Elena, O'Sullivan, Brendan J., Ng, Lai Guan, Roediger, Ben, Thomas, Ranjeny, Weninger, Wolfgang and de St Groth, Barbara Fazekas (2011). Langerhans cells are precommitted to immune tolerance induction. Proceedings of the National Academy of Sciences of the United States of America, 108 (44), 18049-18054. doi: 10.1073/pnas.1110076108

Langerhans cells are precommitted to immune tolerance induction

2011

Journal Article

Targeting curcusomes to inflammatory dendritic cells inhibits NF-{kappa}b and improves insulin resistance in obese mice

Yekollu, Suman Kumar, Thomas, Ranjeny and O'Sullivan, Brendan (2011). Targeting curcusomes to inflammatory dendritic cells inhibits NF-{kappa}b and improves insulin resistance in obese mice. Diabetes, 60 (11), 2928-2938. doi: 10.2337/db11-0275

Targeting curcusomes to inflammatory dendritic cells inhibits NF-{kappa}b and improves insulin resistance in obese mice

2011

Journal Article

Immunotherapy with costimulatory dendritic cells to control autoimmune inflammation

O'Sullivan, Brendan J., Pai, Saparna, Street, Shayna, An, Xiayou, Macdonald, Kelli P. A., Wong, Michelle, Strutton, Geoffrey, Gerondakis, Steve, Steptoe, Raymond J., Fazekas de St Groth, Barbara, Hill, Geoffrey R. and Thomas, Ranjeny (2011). Immunotherapy with costimulatory dendritic cells to control autoimmune inflammation. Journal of Immunology, 187 (7), 4018-4030. doi: 10.4049/jimmunol.1101727

Immunotherapy with costimulatory dendritic cells to control autoimmune inflammation

2011

Journal Article

CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis

McNally, Alice, Hill, Geoffrey R., Sparwasser, Tim, Thomas, Ranjeny and Steptoe, Raymond J. (2011). CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis. Proceedings of the National Academy of Sciences of the United States of America, 108 (18), 7529-7534. doi: 10.1073/pnas.1103782108

CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis

2011

Journal Article

Reduced soluble receptor for advanced glycation end-products in COPD

Smith, D. J., Yerkovich, S. T., Towers, M. A., Carroll, M. L., Thomas, R. and Upham, J. W. (2011). Reduced soluble receptor for advanced glycation end-products in COPD. European Respiratory Journal, 37 (3), 516-522. doi: 10.1183/09031936.00029310

Reduced soluble receptor for advanced glycation end-products in COPD

2011

Journal Article

Interleukin-1 beta produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T-cells: Implications for the timing of tolerizing immunotherapy

Bertin-Maghit, Sebastien, Pang, Dimeng, O'Sullivan, Brendan, Best, Shannon, Duggan, Emily, Paul, Sanjoy, Thomas, Helen, Kay, Thomas W. H., Harrison, Leonard C., Steptoe, Raymond and Thomas, Ranjeny (2011). Interleukin-1 beta produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T-cells: Implications for the timing of tolerizing immunotherapy. Diabetes, 60 (1), 248-257. doi: 10.2337/db10-0104

Interleukin-1 beta produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T-cells: Implications for the timing of tolerizing immunotherapy

2011

Journal Article

Streptococcus pneumoniae infection suppresses allergic airways disease by inducing regulatory T-cells

Preston, J. A., Thorburn, A. N., Starkey, M. R., Beckett, E. L., Horvat, J. C., Wade, M. A., O'Sullivan, B. J., Thomas, R., Beagley, K. W., Gibson, P. G., Foster, P. S. and Hansbro, P. M. (2011). Streptococcus pneumoniae infection suppresses allergic airways disease by inducing regulatory T-cells. European Respiratory Journal, 37 (1), 53-64. doi: 10.1183/09031936.00049510

Streptococcus pneumoniae infection suppresses allergic airways disease by inducing regulatory T-cells

2010

Journal Article

Pneumococcal conjugate vaccine-induced regulatory T cells suppress the development of allergic airways disease

Thorburn, Alison N., O'Sullivan, Brendan J., Thomas, Ranjeny, Kumar, Rakesh K., Foster, Peter S., Gibson, Peter G. and Hansbro, Philip M. (2010). Pneumococcal conjugate vaccine-induced regulatory T cells suppress the development of allergic airways disease. Thorax, 65 (12), 1053-1060. doi: 10.1136/thx.2009.131508

Pneumococcal conjugate vaccine-induced regulatory T cells suppress the development of allergic airways disease

2010

Journal Article

IL-1 signalling determines the fate of skin grafts expressing non-self protein in keratinocytes

Hadis, Usriansyah, Leggatt, Graham R., Thomas, Ranjeny, Frazer, Ian H. and Kovacs, Eva M. (2010). IL-1 signalling determines the fate of skin grafts expressing non-self protein in keratinocytes. Experimental Dermatology, 19 (8), 723-729. doi: 10.1111/j.1600-0625.2010.01092.x

IL-1 signalling determines the fate of skin grafts expressing non-self protein in keratinocytes

2010

Journal Article

c-Rel is required for the development of thymic Foxp3(+) CD4 regulatory T cells (vol 206, pg 3001, 2009)

Isomura, Iwao, Palmer, Stephanie, Grumont, Raelene J., Bunting, Karen, Hoyne, Gerard, Wilkinson, Nancy, Banerjee, Ashish, Proietto, Anna, Gugasyan, Raffi, Wu, Li, McNally, Alice, Steptoe, Raymond J., Thomas, Ranjeny, Shannon, M. Frances and Gerondakis, Steve (2010). c-Rel is required for the development of thymic Foxp3(+) CD4 regulatory T cells (vol 206, pg 3001, 2009). Journal of Experimental Medicine, 207 (4)

c-Rel is required for the development of thymic Foxp3(+) CD4 regulatory T cells (vol 206, pg 3001, 2009)

2010

Journal Article

c-Rel is required for the development of thymic Foxp3+ CD4 regulatory T cells (The Journal of Experimental Medicine (December 21, 2009) 206, 13 (3001-3014))

Isomura, Iwao, Palmer, Stephanie, Grumont, Raelene J., Bunting, Karen, Hoyne, Gerard, Wilkinson, Nancy, Banerjee, Ashish, Proietto, Anna, Gugasyan, Raffi, Wu, Li, McNally, Alice, Steptoe, Raymond J., Thomas, Ranjeny, Shannon, M. Frances and Gerondakis, Steve (2010). c-Rel is required for the development of thymic Foxp3+ CD4 regulatory T cells (The Journal of Experimental Medicine (December 21, 2009) 206, 13 (3001-3014)). Journal of Experimental Medicine, 207 (4), 899-899. doi: 10.1084/jem.2009141132610c

c-Rel is required for the development of thymic Foxp3+ CD4 regulatory T cells (The Journal of Experimental Medicine (December 21, 2009) 206, 13 (3001-3014))

2010

Journal Article

The balancing act of autoimmunity: Central and peripheral tolerance versus infection control

Thomas, Ranjeny (2010). The balancing act of autoimmunity: Central and peripheral tolerance versus infection control. International Reviews of Immunology, 29 (2), 211-233. doi: 10.3109/08830180903434219

The balancing act of autoimmunity: Central and peripheral tolerance versus infection control

2010

Journal Article

A physiological function of inflammation-associated SerpinB2 is regulation of adaptive immunity

Schroder, Wayne A., Le, Thuy T. T., Major, Lee, Street, Shayna, Gardner, Joy, Lambley, Eleanore, Markey, Kate, MacDonald, Kelli P., Fish, Richard J., Thomas, Ranjeny and Suhrbier, Andreas (2010). A physiological function of inflammation-associated SerpinB2 is regulation of adaptive immunity. Journal of Immunology, 184 (5), 2663-2670. doi: 10.4049/jimmunol.0902187

A physiological function of inflammation-associated SerpinB2 is regulation of adaptive immunity

2010

Journal Article

Targeting antigen to diverse APCs inactivates memory CD8+ T cells without eliciting tissue-destructive effector function

Kenna, Tony J., Waldie, Tanya, McNally, Alice, Thomson, Meagan, Yagita, Hideo, Thomas, Ranjeny and Steptoe, Raymond J. (2010). Targeting antigen to diverse APCs inactivates memory CD8+ T cells without eliciting tissue-destructive effector function. Journal of Immunology, 184 (2), 598-606. doi: 10.4049/jimmunol.0900032

Targeting antigen to diverse APCs inactivates memory CD8+ T cells without eliciting tissue-destructive effector function

2009

Journal Article

c-Rel is required for the development of thymic Foxp3(+) CD4 regulatory T cells

Isomura, I., Palmer, S., Grumont, R. J., Bunting, K., Hoyne, G., Wilkinson, N., Banerjee, A., Proietto, A., Gugasyan, R., Li, W., McNally, Alice, Steptoe, Raymond J., Thomas, Ranjeny, Shannon, F. and Gerondakis, S. (2009). c-Rel is required for the development of thymic Foxp3(+) CD4 regulatory T cells. The Journal of Experimental Medicine, 206 (13), 3001-3014. doi: 10.1084/jem.20091411

c-Rel is required for the development of thymic Foxp3(+) CD4 regulatory T cells

2009

Journal Article

Steady-state dendritic cells continuously inactivate T cells that escape thymic negative selection

Doan, Tracy, McNally, Alice, Thomas, Ranjeny and Steptoe, Raymond (2009). Steady-state dendritic cells continuously inactivate T cells that escape thymic negative selection. Immunology and Cell Biology, 87 (8), 615-622. doi: 10.1038/icb.2009.46

Steady-state dendritic cells continuously inactivate T cells that escape thymic negative selection