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2021

Conference Publication

Antigen-expanded t cells infiltrating new-onset rheumatoid arthritis synovial tissue are IL-6-reponsive, T-helper 2 and pro-inflammatory viral-specific clones

Wehr, Pascale, Nel, Hendrik J., Zhou, Chenhao, Mehdi, Ahmed M., McGuire, Helen, Weedon, Helen, Small, Annabelle, Steptoe, Raymond, Gras, Stephanie, Wechalekar, Mihir D. and Thomas, Ranjeny (2021). Antigen-expanded t cells infiltrating new-onset rheumatoid arthritis synovial tissue are IL-6-reponsive, T-helper 2 and pro-inflammatory viral-specific clones. Australian Rheumatology Association 61st Annual Scientific Meeting, Hybrid Meeting, 21–23 May 2021. Richmond, VIC, Australia: Wiley-Blackwell.

Antigen-expanded t cells infiltrating new-onset rheumatoid arthritis synovial tissue are IL-6-reponsive, T-helper 2 and pro-inflammatory viral-specific clones

2020

Conference Publication

Curdlan-induced villous permeability, luminal pathobiont translocation to the ileal crypts, ileitis and arthritis are mitigated by clostridia in colonised germ-free SKG mice

Bergot, Anne-Sophie, Giri, Rabina, Cameron, Amy, Duggan, Emily, Loayza, Jeimy Jimenez, Morrison, Mark, Rehaume, Linda, Begun, Jakob and Thomas, Ranjeny (2020). Curdlan-induced villous permeability, luminal pathobiont translocation to the ileal crypts, ileitis and arthritis are mitigated by clostridia in colonised germ-free SKG mice. Annual Meeting of the American-College-of-Rheumatology (ACR), Virtual, 5-9 November 2020. Hoboken, NJ USA: John Wiley & Sons.

Curdlan-induced villous permeability, luminal pathobiont translocation to the ileal crypts, ileitis and arthritis are mitigated by clostridia in colonised germ-free SKG mice

2020

Conference Publication

Mapping Oligoclonally Expanded T Cells Within the Peripheral and Synovial Immune Landscape of Untreated ACPA plus Rheumatoid Arthritis Patients at the Single Cell Level

Wehr, Pascale, Nel, Hendrik, Zhou, Chenhao, Mehdi, Ahmed, Christ, Angelika, Weedon, Helen, Wechalekar, Mihir and Thomas, Ranjeny (2020). Mapping Oligoclonally Expanded T Cells Within the Peripheral and Synovial Immune Landscape of Untreated ACPA plus Rheumatoid Arthritis Patients at the Single Cell Level. ACR Convergence 2020, Virtual, 5-9 November 2020. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/art.41538

Mapping Oligoclonally Expanded T Cells Within the Peripheral and Synovial Immune Landscape of Untreated ACPA plus Rheumatoid Arthritis Patients at the Single Cell Level

2019

Conference Publication

COMPARISON OF MORTALITY IN RHEUMATOID ARTHRITIS AND DIABETES - THE HUNT POPULATION-BASED STUDY

Houge, Ingrid Saether, Hoff, Mari, Thomas, Ranjeny and Videm, Vibeke (2019). COMPARISON OF MORTALITY IN RHEUMATOID ARTHRITIS AND DIABETES - THE HUNT POPULATION-BASED STUDY. Annual European Congress of Rheumatology (EULAR), Madrid Spain, Jun 12-15, 2019. LONDON: BMJ PUBLISHING GROUP. doi: 10.1136/annrheumdis-2019-eular.1781

COMPARISON OF MORTALITY IN RHEUMATOID ARTHRITIS AND DIABETES - THE HUNT POPULATION-BASED STUDY

2019

Conference Publication

Immune responses to the microbiome tune MHC class II antigen presentation by the intestinal epithelium to control gut pathology

Koyama, Motoko, Mukhopadhyay, Pamela, Schuster, Iona S., Henden, Andrea S., Hülsdünker, Jan, Varelias, Antiopi, Vetizou, Marie, Kuns, Rachel D., Robb, Renee J., Zhang, Ping, Blazar, Bruce R., Thomas, Ranjeny, Begun, Jakob, Waddell, Nicola, Trinchieri, Giorgio, Zeiser, Robert, Clouston, Andrew D., Degli-Esposti, Mariapia A. and Hill, Geoffrey R. (2019). Immune responses to the microbiome tune MHC class II antigen presentation by the intestinal epithelium to control gut pathology. Immunology 2019™ Meeting, San Diego, CA United States, 9-13 May 2019. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.202.supp.69.38

Immune responses to the microbiome tune MHC class II antigen presentation by the intestinal epithelium to control gut pathology

2019

Conference Publication

CD4+CD25+CD127HI cells correlate with length of remission in type 1 diabetes: validated in a multi-site study

Narsale, A., Moya, R., Robertson, H., Payne, D., Lu, T. T., Geoffery, R., Buchanan, K., Harris, M., Bergot, A. S., Thomas, R., Hessner, M., Battaglia, M., Serti, E. and Davies, J. (2019). CD4+CD25+CD127HI cells correlate with length of remission in type 1 diabetes: validated in a multi-site study. International Conference on Lymphocyte Engineering (ICLE), London, United Kingdom, 13-15 September 2019. New Rochelle, NY United States: Mary Ann Liebert. doi: 10.1089/hum.2019.29091.abstracts

CD4+CD25+CD127HI cells correlate with length of remission in type 1 diabetes: validated in a multi-site study

2019

Conference Publication

A phase I, randomized, double-blind, placebo-controlled, single center, single-dose escalation to investigate the safety, tolerability, and pharmacodynamics of subcutaneously administered DEN-181 in adult patients with ACPA plus rheumatoid arthritis on stable methotrexate

Sonigra, Amee, Nel, Hendrik, Ramnoruth, Nishta, Talekar, Meghna, Tesiram, Joanne, Stuurman, Frederik, Proctor, Lavinia, Roberts, Helen, Thurmond, Robin, Vecchio, Phillip, Gourley, Ian, Rigby, Mark, Felix, Nathan, Becart, Stephane, Campbell, Kim and Thomas, Ranjeny (2019). A phase I, randomized, double-blind, placebo-controlled, single center, single-dose escalation to investigate the safety, tolerability, and pharmacodynamics of subcutaneously administered DEN-181 in adult patients with ACPA plus rheumatoid arthritis on stable methotrexate. 2019 ACR/ARP Annual Meeting, Atlanta, GA, United States, 8 - 13 November 2019. Hoboken, NJ, United States: John Wiley & Sons.

A phase I, randomized, double-blind, placebo-controlled, single center, single-dose escalation to investigate the safety, tolerability, and pharmacodynamics of subcutaneously administered DEN-181 in adult patients with ACPA plus rheumatoid arthritis on stable methotrexate

2018

Conference Publication

Antigen-Specific CD4 regulation by Liposomes encapsulating calcitriol and ChgA mimotope in NOD mice

Bergot, A. S., Buckle,, Wright, C., Talekar, M., Hamilton-Williams, E. and Thomas, R. (2018). Antigen-Specific CD4 regulation by Liposomes encapsulating calcitriol and ChgA mimotope in NOD mice. 15th International Symposium on Dendritic Cells (DC), Aachen, Germany, 10-14 June 2018. Hoboken, NJ, United States: Wiley. doi: 10.1002/eji.201871000

Antigen-Specific CD4 regulation by Liposomes encapsulating calcitriol and ChgA mimotope in NOD mice

2018

Conference Publication

Cardiorespiratory fitness in patients with rheumatoid arthritis

Liff, M. H., Hoff, M., Fremo, T., Wisloff, U., Thomas, R. and Videm, V. (2018). Cardiorespiratory fitness in patients with rheumatoid arthritis. Congress of the European League Against Rheumatism (EULAR), Amsterdam, Netherlands, 13-16 June 2018. London, United Kingdom: BMJ Group. doi: 10.1136/annrheumdis-2018-eular.5497

Cardiorespiratory fitness in patients with rheumatoid arthritis

2018

Conference Publication

Pre-clinical clonally-expanded aggrecan89-103-specific CD4+T cells are a target for autoimmune arthritis prevention

Wehr, Pascale, Nel, Hendrik, Law, Soi Cheng, Jansen, Diahann, La Gruta, Nicole, Reid, Hugh, Rossjohn, Jamie and Thomas, Ranjeny (2018). Pre-clinical clonally-expanded aggrecan89-103-specific CD4+T cells are a target for autoimmune arthritis prevention. 2018 ACR/ARHP Annual Meeting, Chicago, Il United States, 19-24 October 2018. Hoboken, NJ United States: John Wiley & Sons.

Pre-clinical clonally-expanded aggrecan89-103-specific CD4+T cells are a target for autoimmune arthritis prevention

2018

Conference Publication

Towards T cell tolerance in rheumatoid arthritis

Thomas, R. (2018). Towards T cell tolerance in rheumatoid arthritis. Congress of the European League Against Rheumatism (EULAR), Amsterdam, Netherlands, 13-16 June 2018. London, United Kingdom: BMJ Group. doi: 10.1136/annrheumdis-2018-eular.7793

Towards T cell tolerance in rheumatoid arthritis

2018

Conference Publication

The Australian arthritis and autoimmune biobank collabortive (A3BC) protocol

March, L., Willers, C., Ellis, J., Cobb, J., Lester, S., Buchbinder, R., Wechalekar, M., Munro, J., Benham, H., Jackson, C., Xue, M., Hill, C., Kenna, T., Keen, H., Perera, C., Hassett, G., Singh-Grewal, D., Richards, B., Lassere, M., Youssef, P., Lim,, Walsh, P., Thomas, R., Brown, M., Adib, N., Barrett, C., Ng, J., Rischmueller, M., Boros, C. ... Murray, K. (2018). The Australian arthritis and autoimmune biobank collabortive (A3BC) protocol. Australian Rheumatology Association Annual Scientific Meeting with the Rheumatology Health Professionals Association, Melbourne, VIC, Australia, 5 - 8 May 2018. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/imj.13772

The Australian arthritis and autoimmune biobank collabortive (A3BC) protocol

2018

Conference Publication

Intestinal inflammatory regulation in murine and human spondyloarthropathy requires high-affinity T cell receptor-zeta chain-associated protein (ZAP) 70-mediated runt-related transcription factor (Runx) 3 activity

Bhuyan, Zaied Ahmed, Rahman, M. Arifur, Maradana, Muralidhara, Mehdi, Ahmed, Guggino, Giuliana, Leo, Paul, Rehaume, Linda, Brown, Matthew, Ciccia, Francesco and Thomas, Ranjeny (2018). Intestinal inflammatory regulation in murine and human spondyloarthropathy requires high-affinity T cell receptor-zeta chain-associated protein (ZAP) 70-mediated runt-related transcription factor (Runx) 3 activity. 2018 ACR/ARHP Annual Meeting, Chicago, Illinois, 19-24 October 2018. Hoboken, NJ, United States: John Wiley & Sons.

Intestinal inflammatory regulation in murine and human spondyloarthropathy requires high-affinity T cell receptor-zeta chain-associated protein (ZAP) 70-mediated runt-related transcription factor (Runx) 3 activity

2017

Conference Publication

Streptococcus Species Enriched in the Oral Cavity of RA Patients: A Persistent Source of Peptidoglycan-Polysaccharide Polymers Which Drive Disseminated Synovial Inflammation

Moentadj, Rabia, Rehaume, Linda, Cuiv, Paraic O., Ormerod, Kate, Maradana, Muralidhara, Lakis, Vanessa Anne, Morrison, Mark, Hugenholtz, Philip, Benham, Helen, Le Cao, Kim-Anh and Thomas, Ranjeny (2017). Streptococcus Species Enriched in the Oral Cavity of RA Patients: A Persistent Source of Peptidoglycan-Polysaccharide Polymers Which Drive Disseminated Synovial Inflammation. 2017 ACR/ARHP Annual Meeting, San Diego CA, United States, 3–8 November 2017. Hoboken, NJ United States: John Wiley & Sons. doi: 10.1002/art.40321

Streptococcus Species Enriched in the Oral Cavity of RA Patients: A Persistent Source of Peptidoglycan-Polysaccharide Polymers Which Drive Disseminated Synovial Inflammation

2017

Conference Publication

Identification of clinician and patient barriers to the implementation of a patient-centered treat to target strategy for rheumatoid arthritis in Australia

Benham, H., Nash, P., Thomas, R. and Van Driel, M. (2017). Identification of clinician and patient barriers to the implementation of a patient-centered treat to target strategy for rheumatoid arthritis in Australia. New Zealand Rheumatology Association and Australian Rheumatology Association with the Rheumatology Health Professionals Association Joint Annual Scientific Meeting, Auckland, New Zealand, 20–23 May 2017. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/imj.13426

Identification of clinician and patient barriers to the implementation of a patient-centered treat to target strategy for rheumatoid arthritis in Australia

2017

Conference Publication

Chlamydia-Infected Macrophages: "Trojan Horses" for Dissemination of IL-23 and TNF-Mediated Inflammation in SKG Mouse Reactive Arthritis

Baillet, Athan, Bhuyan, Zaied Ahmed, Douillard, Claire, Bozon, Aurelie, Armitage, Charles, Romand, Xavier, Minh Vu Chuong Nguyen,, Favier, Bertrand, Wells, Timothy, Beagley, Kenneth and Thomas, Ranjeny (2017). Chlamydia-Infected Macrophages: "Trojan Horses" for Dissemination of IL-23 and TNF-Mediated Inflammation in SKG Mouse Reactive Arthritis. 2017 ACR/ARHP Pediatric Rheumatology Symposium, San Diego, CA, United States, 3-8 November 2017. Hoboken, NJ, United States: John Wiley & Sons.

Chlamydia-Infected Macrophages: "Trojan Horses" for Dissemination of IL-23 and TNF-Mediated Inflammation in SKG Mouse Reactive Arthritis

2017

Conference Publication

Antigen specific immunotherapy for autoimmune disease targeting dendritic cells

Bergot, Anne-Sophie, Talekar, Meghna, Nel, Hanno, Galea, Ryan, Harris, Mark, Hamilton-Williams, Emma and Thomas, Ranjeny (2017). Antigen specific immunotherapy for autoimmune disease targeting dendritic cells. 5th Annual Meeting of the International Cytokine and Interferon Society (ICIS), Kanazawa Japan, 29 October - 2 November 2017. London United Kingdom: Elsevier.

Antigen specific immunotherapy for autoimmune disease targeting dendritic cells

2017

Conference Publication

Mucosal-associated invariant T cells are an important source of TNF in rheumatoid arthritis

Jansen, Diahann, Klinken, Elizabeth, Nel, Hendrik, Law, Soi Cheng, Koppejan, Hester, Hameetman, Marjolijn, Liu, Ligong, Corbett, Alexandra, Eckle, Sidonia, Fairlie, David, Toes, Rene E. M., van Gaalen, Floris, Rossjohn, Jamie, McCluskey, James and Thomas, Ranjeny (2017). Mucosal-associated invariant T cells are an important source of TNF in rheumatoid arthritis. 2017 ACR/ARHP Annual Meeting, San Diego, California, 3-8 November 2017. Hoboken, NJ, United States: John Wiley & Sons.

Mucosal-associated invariant T cells are an important source of TNF in rheumatoid arthritis

2017

Conference Publication

Skin Migratory Dendritic Cells Targeted and Tolerized By Calcitriol-Peptide Liposomes Supress Antigen-Specific Autoreactive T Cell Expansion and Memory Differentiation to Regulate Autoimmune Arthritis

Galea, Ryan, Nel, Hendrik, Talekar, Meghna, Cole, Suzanne, Cochlin, Karyn, Hitchcock, Shannon, Zeng, Bijun, Yekollu, Suman, Rossjohn, Jamie, Reid, Hugh, Malaviya, Ravi, Shealy, Dave, O'Sullivan, Brendan and Thomas, Ranjeny (2017). Skin Migratory Dendritic Cells Targeted and Tolerized By Calcitriol-Peptide Liposomes Supress Antigen-Specific Autoreactive T Cell Expansion and Memory Differentiation to Regulate Autoimmune Arthritis. 2017 ACR/ARHP Pediatric Rheumatology Symposium, San Diego, California, 3-8 November 2017. Hoboken, NJ, United States: John Wiley & Sons.

Skin Migratory Dendritic Cells Targeted and Tolerized By Calcitriol-Peptide Liposomes Supress Antigen-Specific Autoreactive T Cell Expansion and Memory Differentiation to Regulate Autoimmune Arthritis

2017

Conference Publication

Implementation of a Treat-to-Target Remission Strategy for Rheumatoid Arthritis in Australian Public and Private Rheumatology Clinics - Identification of Clinician and Patient Barriers

Benham, Helen, Chiu, Hedva, Tesiram, Joanne, Landsberg, Peter, Harrison, Andrew A., Nash, Peter, Thomas, Ranjeny and van Driel, Mieke (2017). Implementation of a Treat-to-Target Remission Strategy for Rheumatoid Arthritis in Australian Public and Private Rheumatology Clinics - Identification of Clinician and Patient Barriers. 2017 ACR/ARHP Annual Meeting, San Diego CA, United States, 3–8 November 2017. Hoboken, NJ United States: John Wiley & Sons.

Implementation of a Treat-to-Target Remission Strategy for Rheumatoid Arthritis in Australian Public and Private Rheumatology Clinics - Identification of Clinician and Patient Barriers