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2017

Conference Publication

Skin Migratory Dendritic Cells Targeted and Tolerized By Calcitriol-Peptide Liposomes Supress Antigen-Specific Autoreactive T Cell Expansion and Memory Differentiation to Regulate Autoimmune Arthritis

Galea, Ryan, Nel, Hendrik, Talekar, Meghna, Cole, Suzanne, Cochlin, Karyn, Hitchcock, Shannon, Zeng, Bijun, Yekollu, Suman, Rossjohn, Jamie, Reid, Hugh, Malaviya, Ravi, Shealy, Dave, O'Sullivan, Brendan and Thomas, Ranjeny (2017). Skin Migratory Dendritic Cells Targeted and Tolerized By Calcitriol-Peptide Liposomes Supress Antigen-Specific Autoreactive T Cell Expansion and Memory Differentiation to Regulate Autoimmune Arthritis. 2017 ACR/ARHP Pediatric Rheumatology Symposium, San Diego, California, 3-8 November 2017. Hoboken, NJ, United States: John Wiley & Sons.

Skin Migratory Dendritic Cells Targeted and Tolerized By Calcitriol-Peptide Liposomes Supress Antigen-Specific Autoreactive T Cell Expansion and Memory Differentiation to Regulate Autoimmune Arthritis

2017

Conference Publication

Implementation of a Treat-to-Target Remission Strategy for Rheumatoid Arthritis in Australian Public and Private Rheumatology Clinics - Identification of Clinician and Patient Barriers

Benham, Helen, Chiu, Hedva, Tesiram, Joanne, Landsberg, Peter, Harrison, Andrew A., Nash, Peter, Thomas, Ranjeny and van Driel, Mieke (2017). Implementation of a Treat-to-Target Remission Strategy for Rheumatoid Arthritis in Australian Public and Private Rheumatology Clinics - Identification of Clinician and Patient Barriers. 2017 ACR/ARHP Annual Meeting, San Diego CA, United States, 3–8 November 2017. Hoboken, NJ United States: John Wiley & Sons.

Implementation of a Treat-to-Target Remission Strategy for Rheumatoid Arthritis in Australian Public and Private Rheumatology Clinics - Identification of Clinician and Patient Barriers

2016

Conference Publication

Genetic Association of Ankylosing Spondylitis with TBX21 Influences T-Bet and Pro-Inflammatory Cytokine Expression in Humans and SKG Mice As a Model of Spondyloarthritis and Alters Host Microbiome and Response to Microbial Stimuli

Lau, Max, Keith, Patricia, McCready, Madeline, Costello, Mary-Ellen, Bradbury, Linda, Hollis, Kelly, Thomas, Ranjeny, Thomas, Gethin P., Brown, Matthew A. and Kenna, Tony J. (2016). Genetic Association of Ankylosing Spondylitis with TBX21 Influences T-Bet and Pro-Inflammatory Cytokine Expression in Humans and SKG Mice As a Model of Spondyloarthritis and Alters Host Microbiome and Response to Microbial Stimuli. Annual Meeting of the American-College-of-Rheumatology/Association-of-Rheumatology-Health-Professionals (ACR/ARHP), Washington Dc, Nov 11-16, 2016. HOBOKEN: WILEY.

Genetic Association of Ankylosing Spondylitis with TBX21 Influences T-Bet and Pro-Inflammatory Cytokine Expression in Humans and SKG Mice As a Model of Spondyloarthritis and Alters Host Microbiome and Response to Microbial Stimuli

2016

Conference Publication

Heightened MAIT Cell Sensitivity to MR1 Ligands Could Impact Control of Dysbiosis in Patients with Rheumatoid Arthritis and Ankylosing Spondylitis

Jansen, Diahann, Klinken, Elizabeth, Nel, Hendrik, Law, Soi Cheng, Benham, Helen, Cummins, Lisa, Brown, Matthew, Kenna, Tony, Liu, Ligong, Fairlie, David, Rossjohn, Jamie, Morrison, Mark, Thomas, Ranjeny, Cuiv, Paraic O., McCluskey, James and Corbett, Alexandra (2016). Heightened MAIT Cell Sensitivity to MR1 Ligands Could Impact Control of Dysbiosis in Patients with Rheumatoid Arthritis and Ankylosing Spondylitis. 2016 ACR/ARHP Annual Meeting, Washington, DC, United States, 11-16 November 2016. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/art.39977

Heightened MAIT Cell Sensitivity to MR1 Ligands Could Impact Control of Dysbiosis in Patients with Rheumatoid Arthritis and Ankylosing Spondylitis

2016

Conference Publication

Treatment with dexamethasone and monophosphoryl lipid a removes disease-associated transcriptional signatures in monocyte-derived dendritic cells from rheumatoid arthritis patients and confers the ability to modulate CD4+T cell responses

Garcia-Gonzalez, Paulina, Neira, Oscar, Schinnerling, Katina, Sepulveda-Gutierrez, Alejandro, Maggy, Jaxaira, Hoyos, Lorena, Morales, Rodrigo, Ubilla-Olguin, Gabriela, Mehdi, Ahmed, Nel, Hendrik, Soto, Lilian, Pesce, Barbara, Carmen Molina, Maria, Cuchacovich, Miguel, Larrondo, Milton, Catalan, Diego, Hilkens, Catharien M., Thomas, Ranjeny, Verdugo, Ricardo and Aguillon, Juan C. (2016). Treatment with dexamethasone and monophosphoryl lipid a removes disease-associated transcriptional signatures in monocyte-derived dendritic cells from rheumatoid arthritis patients and confers the ability to modulate CD4+T cell responses. Annual Meeting of the American-College-of-Rheumatology/Association-of-Rheumatology-Health-Professionals (ACR/ARHP), Washington, DC, United States, 11-16 November 2016. Hoboken, NJ, United States: John Wiley & Sons.

Treatment with dexamethasone and monophosphoryl lipid a removes disease-associated transcriptional signatures in monocyte-derived dendritic cells from rheumatoid arthritis patients and confers the ability to modulate CD4+T cell responses

2016

Conference Publication

Dexamethasone and MPLA treatment of monocyte-derived dendritic cells from rheumatoid arthritis patients induce transcriptional modulation of genes related to cell recruitment, signaling and metabolism

Garcia-Gonzalez, P. A., Schinnerling, K., Sepulveda, A., Ubilla-Olguin, G., Soto, L., Neira, O., Medhi, A. M., Nel, H. J., Catalan, D., Thomas, R., Verdugo, R. A. and Aguillon, J. C. (2016). Dexamethasone and MPLA treatment of monocyte-derived dendritic cells from rheumatoid arthritis patients induce transcriptional modulation of genes related to cell recruitment, signaling and metabolism. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley.

Dexamethasone and MPLA treatment of monocyte-derived dendritic cells from rheumatoid arthritis patients induce transcriptional modulation of genes related to cell recruitment, signaling and metabolism

2016

Conference Publication

Clinician Researchers: Understanding the Barriers and Facilitators for Medical Students and Junior Doctors Considering a Career in Research

Benham, Helen, Jensen, Charmaine, Thomas, Ranjeny and Eley, Diann (2016). Clinician Researchers: Understanding the Barriers and Facilitators for Medical Students and Junior Doctors Considering a Career in Research. Australian Rheumatology Association in conjunction with Rheumatology Health Professionals Association, 57th Annual Scientific Meeting, Darwin, NT, Australia, 30 April–4 May 2016. HOBOKEN: Wiley. doi: 10.1111/imj.13052

Clinician Researchers: Understanding the Barriers and Facilitators for Medical Students and Junior Doctors Considering a Career in Research

2016

Conference Publication

Abnormalities of antigen presenting cells in type 1 diabetes

Boks, M., Buchanan, K., Nagl, L., Harris, M. and Thomas, R. (2016). Abnormalities of antigen presenting cells in type 1 diabetes. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley.

Abnormalities of antigen presenting cells in type 1 diabetes

2016

Conference Publication

Molecular basis for the increased susceptibility of Indigenous North American tribes to seropositive rheumatoid arthritis

Scally, S., Law, S. -C, van Heemst, J., Wieles, D., Moustakis, A., Papadopoulos, G., van der Woude, D., Hitchon, C., Robinson, D., Huizinga, T., Reid, H., Toes, R., El-Gabalawy, H., Rossjohn, J. and Thomas, R. (2016). Molecular basis for the increased susceptibility of Indigenous North American tribes to seropositive rheumatoid arthritis. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200

Molecular basis for the increased susceptibility of Indigenous North American tribes to seropositive rheumatoid arthritis

2016

Conference Publication

Restraint of autoreactive T cell expansion is defective in female BALB/c ZAP70(W163C) mutant (SKG) mice

Rahman, M. A., Montizaan, D., Bhuyan, Z. A., Rehaume, L. M. and Thomas, R. (2016). Restraint of autoreactive T cell expansion is defective in female BALB/c ZAP70(W163C) mutant (SKG) mice. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley.

Restraint of autoreactive T cell expansion is defective in female BALB/c ZAP70(W163C) mutant (SKG) mice

2016

Conference Publication

An Australian prospective cohort of rheumatoid arthritis patients and their first-degree relatives characterising environmental, genetic, microbial and immune factors

Benham, Helen, Wood, John, Nagl, Lisa, Maradana, Muralidhara, Daly, Joshua, Lachner, Nancy, Hugenholtz, Philip and Thomas, Ranjeny (2016). An Australian prospective cohort of rheumatoid arthritis patients and their first-degree relatives characterising environmental, genetic, microbial and immune factors. Australian Rheumatology Association in conjunction with Rheumatology Health Professionals Association, 57th Annual Scientific Meeting, Darwin, NT, Australia, 30 April–4 May 2016. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/imj.13052

An Australian prospective cohort of rheumatoid arthritis patients and their first-degree relatives characterising environmental, genetic, microbial and immune factors

2016

Conference Publication

Collagen specific CD4+T-cells restricted by HLA-DRB1*0101 are selected into the repertoire and expand in disease in mice and patients with inflammatory arthritis

Jansen, D. T. S. L., Nel, H. J., Ramnoruth, N., Tesiram, J., Nagl, L., Benham, H., Scally, S., Reed, H. H., Rossjohn, J. and Thomas, R. (2016). Collagen specific CD4+T-cells restricted by HLA-DRB1*0101 are selected into the repertoire and expand in disease in mice and patients with inflammatory arthritis. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200

Collagen specific CD4+T-cells restricted by HLA-DRB1*0101 are selected into the repertoire and expand in disease in mice and patients with inflammatory arthritis

2016

Conference Publication

Treatment of ZAP-70 Mutant SKG Mice with Anti-IL-23 Antibody Alters Fecal Microbiota Composition and Prevents Outgrowth of Bacteria Associated with Susceptibility to Spondyloarthritis and Ileitis

Rehaume, Linda, Matigian, Nicholas, Kang, Alicia, Zbarskaya, Olga, Kikly, Kristine, Lachner, Nancy, Daly, Joshua, Hugenholtz, Philip, Morrison, Mark, Le Cao, Kim-Anh and Thomas, Ranjeny (2016). Treatment of ZAP-70 Mutant SKG Mice with Anti-IL-23 Antibody Alters Fecal Microbiota Composition and Prevents Outgrowth of Bacteria Associated with Susceptibility to Spondyloarthritis and Ileitis. 2016 ACR/ARHP Annual Meeting, Washington, DC United States, 11–16 November 2016 . Hoboken, NJ United States: Wiley.

Treatment of ZAP-70 Mutant SKG Mice with Anti-IL-23 Antibody Alters Fecal Microbiota Composition and Prevents Outgrowth of Bacteria Associated with Susceptibility to Spondyloarthritis and Ileitis

2016

Conference Publication

Ablation of pathogenic memory T-cell responses by bone marrow-mediated gene therapy under immune-preserving conditions

Steptoe, R., Al-Kouba, J., Coleman, M., Jessup, C., Starkey, M., Overgaard, N., Bridge, J., Horvat, J., Werder, R., Walters, S., Coates, P. T., Grey, S., Thomas, R., Wells, J., Hansbro, P., Phipps, S. and Davies, J. (2016). Ablation of pathogenic memory T-cell responses by bone marrow-mediated gene therapy under immune-preserving conditions. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley.

Ablation of pathogenic memory T-cell responses by bone marrow-mediated gene therapy under immune-preserving conditions

2016

Conference Publication

Development of a model for antigen-specific tolerising immunotherapy and response in NOD mice

Buckle, I, Steptoe, R. J., Thomas, R. and Hamilton-Williams, E. E. (2016). Development of a model for antigen-specific tolerising immunotherapy and response in NOD mice. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley.

Development of a model for antigen-specific tolerising immunotherapy and response in NOD mice

2016

Conference Publication

Oligoclonally expanded CD4+T cells recognising citrulinated vimentin in peripheral blood of rheumatoid arthritis patients

Law, S. C., Nel, H. J., Scally, S. W., Mehdi, A., Le Cao, K. -A, Rossjohn, J., Reid, H. H., La Gruta, N. L. and Thomas, R. (2016). Oligoclonally expanded CD4+T cells recognising citrulinated vimentin in peripheral blood of rheumatoid arthritis patients. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200

Oligoclonally expanded CD4+T cells recognising citrulinated vimentin in peripheral blood of rheumatoid arthritis patients

2016

Conference Publication

Profiling immunogenic bacteria within the microbiota of SKG mice associated with spondyloarthritis and ileitis using IgA-SEQ

Rehaume, L. M., Kang, A., Zbarskaya, O., Mullaney, J. A., Kim, M., Cuiv, O. P., Angel, N., Lachner, N., Daly, J., Morrison, M., Hugenholtz, P. and Thomas, R. (2016). Profiling immunogenic bacteria within the microbiota of SKG mice associated with spondyloarthritis and ileitis using IgA-SEQ. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley.

Profiling immunogenic bacteria within the microbiota of SKG mice associated with spondyloarthritis and ileitis using IgA-SEQ

2015

Conference Publication

Profiling at the Single-Cell Level Reveals Evidence for Antigen-Driven Oligoclonal Expansion of Citrullinated Vimentin-Specific CD4+T Cells in Peripheral Blood of Rheumatoid Arthritis (RA) Patients

Law, Soi Cheng, Nel, Hendrik, Rossjohn, Jamie, Reid, Hugh H., La Gruta, Nicole L. and Thomas, Ranjeny (2015). Profiling at the Single-Cell Level Reveals Evidence for Antigen-Driven Oligoclonal Expansion of Citrullinated Vimentin-Specific CD4+T Cells in Peripheral Blood of Rheumatoid Arthritis (RA) Patients. Annual Meeting of the American-College-of-Rheumatology (ACR) and Association-of-Rheumatology-Health-Professionals (ARHP), San Francisco Ca, Nov 06-11, 2015. HOBOKEN: WILEY-BLACKWELL.

Profiling at the Single-Cell Level Reveals Evidence for Antigen-Driven Oligoclonal Expansion of Citrullinated Vimentin-Specific CD4+T Cells in Peripheral Blood of Rheumatoid Arthritis (RA) Patients

2015

Conference Publication

The Shared Rheumatoid Arthritis HLA-DRB1 Susceptibility Epitope Shapes the Molecular Orientation of Citrulline and the Autoreactive T Cell Receptor Repertoire

van Heemst, Jurgen, Scally, Stephen, Law, Soi Cheng, van der Woude, Diane, Hitchon, Carol, Robinson, David B., Huizinga, T. W. J., Reid, Hugh H., Toes, Rene E. M., El-Gabalawy, Hani, Rossjohn, Jamie and Thomas, Ranjeny (2015). The Shared Rheumatoid Arthritis HLA-DRB1 Susceptibility Epitope Shapes the Molecular Orientation of Citrulline and the Autoreactive T Cell Receptor Repertoire. Annual Meeting of the American-College-of-Rheumatology (ACR) and Association-of-Rheumatology-Health-Professionals (ARHP), San Francisco Ca, Nov 06-11, 2015. HOBOKEN: WILEY-BLACKWELL.

The Shared Rheumatoid Arthritis HLA-DRB1 Susceptibility Epitope Shapes the Molecular Orientation of Citrulline and the Autoreactive T Cell Receptor Repertoire

2015

Conference Publication

Profiling Immunogenic Bacteria within the Microbiota of ZAP-70 Mutant SKG Mice Associated with Spondyloarthritis and Ileitis Using IgA-SEQ

Rehaume, Linda, Kang, Alicia, Zbarskaya, Olga, Mullaney, Jane, Kim, Matthew, Cuiv, Paraic O., Angel, Nicola, Hugenholtz, Philip, Morrison, Mark and Thomas, Ranjeny (2015). Profiling Immunogenic Bacteria within the Microbiota of ZAP-70 Mutant SKG Mice Associated with Spondyloarthritis and Ileitis Using IgA-SEQ. 2015 ACR/ARHP Annual Meeting, San Francisco, CA, United States, 6-11 November 2015. Hoboken, NJ, United States: John Wiley & Sons.

Profiling Immunogenic Bacteria within the Microbiota of ZAP-70 Mutant SKG Mice Associated with Spondyloarthritis and Ileitis Using IgA-SEQ