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2011

Journal Article

Toward a new age of cellular pharmacokinetics in drug discovery

Zhou, Fang, Zhang, Jingwei, Li, Peng, Niu, Fang, Wu, Xiaolan, Wang, Guangji and Roberts, Michael S. (2011). Toward a new age of cellular pharmacokinetics in drug discovery. Drug Metabolism Reviews, 43 (3), 335-345. doi: 10.3109/03602532.2011.560607

Toward a new age of cellular pharmacokinetics in drug discovery

2011

Journal Article

Simultaneous quantification of carbamate insecticides in human plasma by liquid chromatography/tandem mass spectrometry

Mostafa, Ahmed, Medley, Gregory, Roberts, Darren M., Mohamed, Mosaad Sayed, Elshanawani, Abdalla A., Roberts, Michael S. and Liu, Xin (2011). Simultaneous quantification of carbamate insecticides in human plasma by liquid chromatography/tandem mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 879 (23), 2234-2238. doi: 10.1016/j.jchromb.2011.06.006

Simultaneous quantification of carbamate insecticides in human plasma by liquid chromatography/tandem mass spectrometry

2011

Journal Article

Changes in antibiotic distribution due to pancreatitis

Fanning, Kent J., Robertson, Thomas A., Prins, Johannes B. and Roberts, Michael S. (2011). Changes in antibiotic distribution due to pancreatitis. Antimicrobial Agents and Chemotherapy, 55 (6), 3008-3011. doi: 10.1128/AAC.00416-10

Changes in antibiotic distribution due to pancreatitis

2011

Journal Article

Nanoparticles and microparticles for skin drug delivery

Prow, Tarl W., Grice, Jeffrey E., Lin, Lynlee L., Faye, Rokhaya, Butler, Margaret, Becker, Wolfgang, Wurm, Elisabeth M. T., Yoong, Corinne, Robertson, Thomas A., Soyer, H. Peter and Roberts, Michael S. (2011). Nanoparticles and microparticles for skin drug delivery. Advanced Drug Delivery Reviews, 63 (6), 470-491. doi: 10.1016/j.addr.2011.01.012

Nanoparticles and microparticles for skin drug delivery

2011

Journal Article

How to measure pharmacokinetics in critically ill patients?

Liu, Xin, Kruger, Peter S. and Roberts, Michael S. (2011). How to measure pharmacokinetics in critically ill patients?. Current Pharmaceutical Biotechnology, 12 (12), 2037-2043. doi: 10.2174/138920111798808239

How to measure pharmacokinetics in critically ill patients?

2011

Journal Article

Hepatic pharmacokinetics of cationic drugs in a high-fat emulsion-induced rat model of nonalcoholic steatohepatitis

Li, Peng, Robertson, Thomas A., Thorling, Camilla A., Zhang, Qian, Fletcher, Linda M., Crawford, Darrell H. G. and Roberts, Michael S. (2011). Hepatic pharmacokinetics of cationic drugs in a high-fat emulsion-induced rat model of nonalcoholic steatohepatitis. Drug Metabolism and Disposition, 39 (4), 571-579. doi: 10.1124/dmd.110.036806

Hepatic pharmacokinetics of cationic drugs in a high-fat emulsion-induced rat model of nonalcoholic steatohepatitis

2011

Journal Article

Non-invasive imaging of skin physiology and percutaneous penetration using fluorescence spectral and lifetime imaging with multiphoton and confocal microscopy

Roberts, Michael S., Dancik, Yuri, Prow, Tarl W., Thorling, Camilla A., Lin, Lynlee L., Grice, Jeffrey E., Robertson, Thomas A., Koenig, Karsten and Becker, Wolfgang (2011). Non-invasive imaging of skin physiology and percutaneous penetration using fluorescence spectral and lifetime imaging with multiphoton and confocal microscopy. European Journal of Pharmaceutics and Biopharmaceutics, 77 (3), 469-488. doi: 10.1016/j.ejpb.2010.12.023

Non-invasive imaging of skin physiology and percutaneous penetration using fluorescence spectral and lifetime imaging with multiphoton and confocal microscopy

2011

Journal Article

Applications of multiphoton tomographs and femtosecond laser nanoprocessing microscopes in drug delivery research

König, Karsten, Raphael, Anthony P., Lin, Li, Grice, Jeffrey E., Soyer, H. Peter, Breunig, H. Georg, Roberts, Michael S. and Prow, Tarl W. (2011). Applications of multiphoton tomographs and femtosecond laser nanoprocessing microscopes in drug delivery research. Advanced Drug Delivery Reviews, 63 (4-5), 388-404. doi: 10.1016/j.addr.2011.03.002

Applications of multiphoton tomographs and femtosecond laser nanoprocessing microscopes in drug delivery research

2011

Journal Article

Changes in the concentrations of creatinine, cystatin C and NGAL in patients with acute paraquat self-poisoning

Roberts, Roberts, Darren M., Wilks, Martin F., Roberts, Michael S., Swaminathan, Ramasamyiyer, Mohamed, Fahim, Dawson, Andrew H. and Buckley, Nick A. (2011). Changes in the concentrations of creatinine, cystatin C and NGAL in patients with acute paraquat self-poisoning. Toxicology Letters, 202 (1), 69-74. doi: 10.1016/j.toxlet.2011.01.024

Changes in the concentrations of creatinine, cystatin C and NGAL in patients with acute paraquat self-poisoning

2011

Journal Article

Continuation of statin therapy in patients with presumed infection: A randomized controlled trial

Kruger, Peter S., Harward, Meg L., Jones, Mark A., Joyce, Christopher J., Kostner, Karam M., Roberts, Michael S. and Venkateshm Bala (2011). Continuation of statin therapy in patients with presumed infection: A randomized controlled trial. American Journal of Respiraty and Critical Care Medicine, 183 (6), 774-781. doi: 10.1164/rccm.201006-0955OC

Continuation of statin therapy in patients with presumed infection: A randomized controlled trial

2011

Journal Article

Antibiotic dosing in the 'at risk' critically ill patient: linking pathophysiology with pharmacokinetics/pharmacodynamics in sepsis and trauma patients

Roberts, Jason A., Roberts, Michael S., Semark, Andrew, Udy, Andrew A., Kirkpatrick, Carl M.J., Paterson, David L., Roberts, Matthew J., Kruger, Peter and Lipman, Jeffrey (2011). Antibiotic dosing in the 'at risk' critically ill patient: linking pathophysiology with pharmacokinetics/pharmacodynamics in sepsis and trauma patients. BMC Anesthesiology, 11 (1) 3, 3.1-3.7. doi: 10.1186/1471-2253-11-3

Antibiotic dosing in the 'at risk' critically ill patient: linking pathophysiology with pharmacokinetics/pharmacodynamics in sepsis and trauma patients

2011

Journal Article

Plasma acetate, gluconate and interleukin-6 profiles during and after cardiopulmonary bypass: a comparison of Plasma-Lyte 148 with a bicarbonate-balanced solution

Davies, Paul G., Venkatesh, Balasubramanian, Morgan, Thomas J., Presneill, Jeffrey J., Kruger, Peter S., Thomas, Bronwyn J., Roberts, Michael S. and Mundy, Julie (2011). Plasma acetate, gluconate and interleukin-6 profiles during and after cardiopulmonary bypass: a comparison of Plasma-Lyte 148 with a bicarbonate-balanced solution. Critical Care, 15 (1) R21, R21-1-R21-8. doi: 10.1186/cc9966

Plasma acetate, gluconate and interleukin-6 profiles during and after cardiopulmonary bypass: a comparison of Plasma-Lyte 148 with a bicarbonate-balanced solution

2011

Journal Article

The pharmacokinetics of cefazolin in patients undergoing elective and semi-elective abdominal aortic aneurysm open repair surgery

Douglas, Alexandra, Altukroni, Mahdi, Udy, Andrew A., Roberts, Michael S., Taraporewalla, Kersi, Jenkins, Jason, Lipman, Jeffrey and Roberts, Jason A. (2011). The pharmacokinetics of cefazolin in patients undergoing elective and semi-elective abdominal aortic aneurysm open repair surgery. BMC Anesthesiology, 11 (1) 5, 5.1-5.5. doi: 10.1186/1471-2253-11-5

The pharmacokinetics of cefazolin in patients undergoing elective and semi-elective abdominal aortic aneurysm open repair surgery

2011

Journal Article

Detection of gabapentin-lactose Maillard reaction product (Schiff's Base): Application to solid dosage form preformulation. Part 1

Monajjemzadeh, Farnaz, Hassanzadeh, Davoud, Valizadeh, Hadi, Siahi-Shadbad, Mohammad R., Mojarrad, Javid Shahbazi, Robertson, Thomas A. and Roberts, Michael S. (2011). Detection of gabapentin-lactose Maillard reaction product (Schiff's Base): Application to solid dosage form preformulation. Part 1. pharmind: Die Pharmazeutische Industrie, 73 (1), 174-177.

Detection of gabapentin-lactose Maillard reaction product (Schiff's Base): Application to solid dosage form preformulation. Part 1

2011

Journal Article

Detection of gabapentin-lactose Maillard reaction product (Schiff's Base): Application to solid dosage form preformulation. Part 2. Bestimmung der Maillard-Reaktionsprodukte (Schiff-Base) von Gabapentin und Lactose: Anwendung auf die Vorformulierung einer

Monajjemzadeh, Farnaz, Hassanzadeh, Davoud, Valizadeh, Hadi, Siahi-Shadbad, Mohammad R., Mojarrad, Javid Shahbazi, Robertson, Thomas A. and Roberts, Michael S. (2011). Detection of gabapentin-lactose Maillard reaction product (Schiff's Base): Application to solid dosage form preformulation. Part 2. Bestimmung der Maillard-Reaktionsprodukte (Schiff-Base) von Gabapentin und Lactose: Anwendung auf die Vorformulierung einer. pharmind: Die Pharmazeutische Industrie, 73 (2), 376-382.

Detection of gabapentin-lactose Maillard reaction product (Schiff's Base): Application to solid dosage form preformulation. Part 2. Bestimmung der Maillard-Reaktionsprodukte (Schiff-Base) von Gabapentin und Lactose: Anwendung auf die Vorformulierung einer

2011

Journal Article

Effect of adjuvant-induced systemic inflammation in rats on hepatic disposition kinetics of taurocholate

Roberts, Michael S., Liu, Xin, Zou, Yuhong, Siebert, Gerhard A., Chang, Ping, Whitehouse, Michael W., Fletcher, Linda and Crawford, Darrell H. G. (2011). Effect of adjuvant-induced systemic inflammation in rats on hepatic disposition kinetics of taurocholate. American Journal of Physiology-gastrointestinal And Liver Physiology, 300 (1), G130-G136. doi: 10.1152/ajpgi.00162.2010

Effect of adjuvant-induced systemic inflammation in rats on hepatic disposition kinetics of taurocholate

2010

Journal Article

Flexible nanosomes (SECosomes) enable efficient siRNA delivery in cultured primary skin cells and in the viable epidermis of ex vivo human skin

Geusens, Barbara, Van Gele, Mireille, Braat, Sien, De Smedt, Stefaan C., Stuart, Marc C. A., Prow, Tarl W., Sanchez, Washington, Roberts, Michael S., Sanders, Niek N. and Lambert, Jo (2010). Flexible nanosomes (SECosomes) enable efficient siRNA delivery in cultured primary skin cells and in the viable epidermis of ex vivo human skin. Advanced Functional Materials, 20 (23), 4077-4090. doi: 10.1002/adfm.201000484

Flexible nanosomes (SECosomes) enable efficient siRNA delivery in cultured primary skin cells and in the viable epidermis of ex vivo human skin

2010

Journal Article

Drug structure-transport relationships

Roberts, MS (2010). Drug structure-transport relationships. Journal of Pharmacokinetics And Pharmacodynamics, 37 (6), 541-573. doi: 10.1007/s10928-010-9174-0

Drug structure-transport relationships

2010

Journal Article

Quantifying pain relief following administration of a novel formulation of paracetamol (Acetaminophen)

Green, Bruce, Chandler, Stephen, MacDonald, Garth, Elliott, Geraldine and Roberts, Michael S. (2010). Quantifying pain relief following administration of a novel formulation of paracetamol (Acetaminophen). Journal of Clinical Pharmacology, 50 (12), 1406-1413. doi: 10.1177/0091270009359181

Quantifying pain relief following administration of a novel formulation of paracetamol (Acetaminophen)

2010

Journal Article

Are commercially available nanoparticles safe when applied to the skin?

Robertson, Thomas A., Sanchez, Washington Y. and Roberts, Michael S. (2010). Are commercially available nanoparticles safe when applied to the skin?. Journal of Biomedical Nanotechnology, 6 (5), 452-468. doi: 10.1166/jbn.2010.1145

Are commercially available nanoparticles safe when applied to the skin?