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2012

Journal Article

Variability of antibiotic concentrations in critically ill patients receiving continuous renal replacement therapy: A multicentre pharmacokinetic study

Roberts, Darren M., Roberts, Jason A., Roberts, Michael S., Liu, Xin, Nair, Priya, Cole, Louise, Lipman, Jeffrey, Bellomo, Rinaldo and on behalf of the RENAL Replacement Therapy Study Investigators (2012). Variability of antibiotic concentrations in critically ill patients receiving continuous renal replacement therapy: A multicentre pharmacokinetic study. Critical Care Medicine, 40 (5), 1523-1528. doi: 10.1097/CCM.0b013e318241e553

Variability of antibiotic concentrations in critically ill patients receiving continuous renal replacement therapy: A multicentre pharmacokinetic study

2012

Journal Article

The pharmacokinetics and pharmacodynamics of cisatracurium in critically ill patients with severe sepsis

Liu, Xin, Kruger, Peter S., Weiss, Michael and Roberts, Michael S. (2012). The pharmacokinetics and pharmacodynamics of cisatracurium in critically ill patients with severe sepsis. British Journal of Clinical Pharmacology, 73 (5), 741-749. doi: 10.1111/j.1365-2125.2011.04149.x

The pharmacokinetics and pharmacodynamics of cisatracurium in critically ill patients with severe sepsis

2012

Journal Article

Convective transport of highly plasma protein bound drugs facilitates direct penetration into deep tissues after topical application

Dancik, Yuri, Anissimov, Yuri G., Jepps, Owen G. and Roberts, Michael S. (2012). Convective transport of highly plasma protein bound drugs facilitates direct penetration into deep tissues after topical application. British Journal of Clinical Pharmacology, 73 (4), 564-578. doi: 10.1111/j.1365-2125.2011.04128.x

Convective transport of highly plasma protein bound drugs facilitates direct penetration into deep tissues after topical application

2012

Journal Article

Determination of trovafloxacin and marbofloxacin in sheep plasma samples by HPLC using UV detection

Mahmood, Adnan H., Medley, Gregory A., Grice, Jeffrey E., Liu, Xin and Roberts, Michael S. (2012). Determination of trovafloxacin and marbofloxacin in sheep plasma samples by HPLC using UV detection. Journal of Pharmaceutical and Biomedical Analysis, 62, 220-223. doi: 10.1016/j.jpba.2012.01.007

Determination of trovafloxacin and marbofloxacin in sheep plasma samples by HPLC using UV detection

2012

Journal Article

Quantum dot penetration into viable human skin

Prow, Tarl W., Monteiro-Riviere, Nancy A., Inman, Alfred O., Grice, Jeffrey E., Chen, Xianfeng, Zhao, Xin, Sanchez, Washington H., Gierden, Audrey, Kendall, Mark A. F., Zvyagin, Andrei V., Erdmann, Detlev, Rivierer, Jim E. and Roberts, Michael S. (2012). Quantum dot penetration into viable human skin. Nanotoxicology, 6 (2), 173-185. doi: 10.3109/17435390.2011.569092

Quantum dot penetration into viable human skin

2012

Journal Article

Continuation of Statin Therapy in patients with presumed infection

Kruger, Peter S., Joyce, Christopher J., Harward, Meg L., Jones, Mark A., Kostner, Karam M., Roberts, Michael S. and Venkatesh, Bala (2012). Continuation of Statin Therapy in patients with presumed infection. American Journal of Respiratory and Critical Care Medicine, 185 (4), 456-457. doi: 10.1164/ajrccm.185.4.456a

Continuation of Statin Therapy in patients with presumed infection

2012

Journal Article

Using pharmacokinetics and pharmacodynamics to optimise dosing of antifungal agents in critically ill patients: A systematic review

Sinnollareddy, Mahipal, Peake, Sandra L., Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2012). Using pharmacokinetics and pharmacodynamics to optimise dosing of antifungal agents in critically ill patients: A systematic review. International Journal of Antimicrobial Agents, 39 (1), 1-10. doi: 10.1016/j.ijantimicag.2011.07.013

Using pharmacokinetics and pharmacodynamics to optimise dosing of antifungal agents in critically ill patients: A systematic review

2012

Journal Article

The human stratum corneum prevents small gold nanoparticle penetration and their potential toxic metabolic consequences

Liu, David C., Raphael, Anthony P., Sundh, Daniel, Grice, Jeffrey E., Soyer, H. Peter, Roberts, Michael S. and Prow, Tarl W. (2012). The human stratum corneum prevents small gold nanoparticle penetration and their potential toxic metabolic consequences. Journal of Nanomaterials, 2012 (1) 721706, 72176.1-72176.8. doi: 10.1155/2012/721706

The human stratum corneum prevents small gold nanoparticle penetration and their potential toxic metabolic consequences

2011

Journal Article

Characterization of optical properties of ZnO nanoparticles for quantitative imaging of transdermal transport

Song, Zhen, Kelf, Timothy A., Sanchez, Washington H., Roberts, Michael S., Ricka, Jaro, Frenz, Martin and Zvyagin, Andrei V. (2011). Characterization of optical properties of ZnO nanoparticles for quantitative imaging of transdermal transport. Biomedical Optics Express, 2 (12), 3321-3333. doi: 10.1364/BOE.2.003321

Characterization of optical properties of ZnO nanoparticles for quantitative imaging of transdermal transport

2011

Journal Article

Pharmacokinetic evaluation of fluconazole in critically ill patients

Sinnollareddy, Mahipal, Peake, Sandra L., Roberts, Michael S., Playford, E. Geoffrey, Lipman, Jeffrey and Roberts, Jason A. (2011). Pharmacokinetic evaluation of fluconazole in critically ill patients. Expert Opinion On Drug Metabolism and Toxicology, 7 (11), 1431-1440. doi: 10.1517/17425255.2011.615309

Pharmacokinetic evaluation of fluconazole in critically ill patients

2011

Journal Article

Multiphoton microscopy can visualize zonal damage and decreased cellular metabolic activity in hepatic ischemia-reperfusion injury in rats

Thorling, Camilla A., Liu, Xin, Burczynski, Frank J., Fletcher, Linda M., Gobe, Glenda C. and Roberts, Michael S. (2011). Multiphoton microscopy can visualize zonal damage and decreased cellular metabolic activity in hepatic ischemia-reperfusion injury in rats. Journal of Biomedical Optics, 16 (11) 116011, 116011-1160118. doi: 10.1117/1.3647597

Multiphoton microscopy can visualize zonal damage and decreased cellular metabolic activity in hepatic ischemia-reperfusion injury in rats

2011

Journal Article

Hair follicles contribute significantly to penetration through human skin only at times soon after application as a solvent deposited solid in man

Liu, Xin, Grice, Jeff E., Lademann, Juergen, Otberg, Nina, Trauer, Sindy, Patzelt, Alexa and Roberts, Michael S. (2011). Hair follicles contribute significantly to penetration through human skin only at times soon after application as a solvent deposited solid in man. British Journal of Clinical Pharmacology, 72 (5), 768-774. doi: 10.1111/j.1365-2125.2011.04022.x

Hair follicles contribute significantly to penetration through human skin only at times soon after application as a solvent deposited solid in man

2011

Journal Article

Plasma and tissue pharmacokinetics of cefazolin in patients undergoing elective and semielective abdominal aortic aneurysm open repair surgery

Douglas, Alexandra, Udy, Andrew A., Wallis, Steven C., Jarrett, Paul, Stuart, Janine, Lassig-Smith, Melissa, Deans, Renae, Roberts, Michael S., Taraporewalla, Kersi, Jenkins, Jason, Medley, Gregory, Lipman, Jeffrey and Roberts, Jason A. (2011). Plasma and tissue pharmacokinetics of cefazolin in patients undergoing elective and semielective abdominal aortic aneurysm open repair surgery. Antimicrobial Agents and Chemotherapy, 55 (11), 5238-5242. doi: 10.1128/AAC.05033-11

Plasma and tissue pharmacokinetics of cefazolin in patients undergoing elective and semielective abdominal aortic aneurysm open repair surgery

2011

Journal Article

Time-correlated single photon counting for simultaneous monitoring Of zinc oxide nanoparticles and NAD(P)H in intact and barrier-disrupted volunteer skin

Lin, Lynlee L., Grice, Jeffrey E., Butler, Margaret K., Zvyagin, Andrei V., Becker, Wolfgang, Robertson, Thomas A., Soyer, H. Peter, Roberts, Michael S. and Prow, Tarl W. (2011). Time-correlated single photon counting for simultaneous monitoring Of zinc oxide nanoparticles and NAD(P)H in intact and barrier-disrupted volunteer skin. Pharmaceutical Research, 28 (11), 2920-2930. doi: 10.1007/s11095-011-0515-5

Time-correlated single photon counting for simultaneous monitoring Of zinc oxide nanoparticles and NAD(P)H in intact and barrier-disrupted volunteer skin

2011

Journal Article

Simple and sensitive liquid chromatography-tandem mass spectrometry methods for quantification of paraquat in plasma and urine: Application to experimental and clinical toxicological studies

Wunnapuk, Klintean, Medley, Gregory A., Liu, Xin, Grice, Jeffrey E., Jayasinghe, Sudheera, Gawarammana, Indika, Buckley, Nicholas A. and Roberts, Michael S. (2011). Simple and sensitive liquid chromatography-tandem mass spectrometry methods for quantification of paraquat in plasma and urine: Application to experimental and clinical toxicological studies. Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences, 879 (28), 3047-3052. doi: 10.1016/j.jchromb.2011.09.008

Simple and sensitive liquid chromatography-tandem mass spectrometry methods for quantification of paraquat in plasma and urine: Application to experimental and clinical toxicological studies

2011

Journal Article

Mathematical models of skin permeability: An overview

Mitragotri, Samir, Anissimov, Yuri G., Bunge, Annette L., Frasch, H. Frederick, Guy, Richard H., Hadgraft, Jonathan, Kasting, Gerald B., Lane, Majella E. and Roberts, Michael S. (2011). Mathematical models of skin permeability: An overview. International Journal of Pharmaceutics, 418 (1), 115-129. doi: 10.1016/j.ijpharm.2011.02.023

Mathematical models of skin permeability: An overview

2011

Journal Article

Modelling dermal drug distribution after topical application in human

Anissimov, Yuri G. and Roberts, Michael Stephen (2011). Modelling dermal drug distribution after topical application in human. Pharmaceutical Research, 28 (9), 2119-2129. doi: 10.1007/s11095-011-0437-2

Modelling dermal drug distribution after topical application in human

2011

Journal Article

Gold nanoparticle penetration and reduced metabolism in human skin by toluene

Labouta, H. I., Liu, D. C., Lin, L. L., Butler, M. K., Grice, J. E., Raphael, A. P., Kraus, T., El-Khordagui, L. K., Soyer, H. P., Roberts, M. S., Schneider, M. and Prow, T. W. (2011). Gold nanoparticle penetration and reduced metabolism in human skin by toluene. Pharmaceutical Research, 28 (11), 2931-2944. doi: 10.1007/s11095-011-0561-z

Gold nanoparticle penetration and reduced metabolism in human skin by toluene

2011

Journal Article

Toward a new age of cellular pharmacokinetics in drug discovery

Zhou, Fang, Zhang, Jingwei, Li, Peng, Niu, Fang, Wu, Xiaolan, Wang, Guangji and Roberts, Michael S. (2011). Toward a new age of cellular pharmacokinetics in drug discovery. Drug Metabolism Reviews, 43 (3), 335-345. doi: 10.3109/03602532.2011.560607

Toward a new age of cellular pharmacokinetics in drug discovery

2011

Journal Article

Simultaneous quantification of carbamate insecticides in human plasma by liquid chromatography/tandem mass spectrometry

Mostafa, Ahmed, Medley, Gregory, Roberts, Darren M., Mohamed, Mosaad Sayed, Elshanawani, Abdalla A., Roberts, Michael S. and Liu, Xin (2011). Simultaneous quantification of carbamate insecticides in human plasma by liquid chromatography/tandem mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 879 (23), 2234-2238. doi: 10.1016/j.jchromb.2011.06.006

Simultaneous quantification of carbamate insecticides in human plasma by liquid chromatography/tandem mass spectrometry