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2009

Journal Article

Development and validation of a reversed-phase high-performance liquid chromatographic method for quantification of peptide dendrimers in human skin permeation experiments

Mutalik, S., Hewavitharana, A., Shaw, P. N., Anissimov, Y. G., Roberts, M. S. and Parekh, H. S. (2009). Development and validation of a reversed-phase high-performance liquid chromatographic method for quantification of peptide dendrimers in human skin permeation experiments. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 877 (29), 3556-3562. doi: 10.1016/j.jchromb.2009.08.039

Development and validation of a reversed-phase high-performance liquid chromatographic method for quantification of peptide dendrimers in human skin permeation experiments

2009

Journal Article

Tissue accumulation of cephalothin in burns: A comparative study by microdialysis of subcutaneous interstitial fluid cephalothin concentrations in burn patients and healthy volunteers

Dalley, A.J., Lipman, J., Deans, R., Venkatesh, B., Rudd, M., Roberts, M.S. and Cross, S.E. (2009). Tissue accumulation of cephalothin in burns: A comparative study by microdialysis of subcutaneous interstitial fluid cephalothin concentrations in burn patients and healthy volunteers. Antimicrobial Agents and Chemotherapy, 53 (1), 210-215. doi: 10.1128/AAC.00718-08

Tissue accumulation of cephalothin in burns: A comparative study by microdialysis of subcutaneous interstitial fluid cephalothin concentrations in burn patients and healthy volunteers

2009

Journal Article

Herb-Drug interactions: In vivo and in vitro effect of shenmai injection, a herbal preparation, on the metabolic activities of hepatic cytochrome P450 3A1/2, 2C6, 1A2, and 2E1 in Rats

Xia, C.H., Sun, J.G., Wang, G.J., Shang, L.L., Zhang, X.X., Zhang, R., Peng, Y., Wang, X.J., Hao, H.P., Xie, L. and Roberts, M.S. (2009). Herb-Drug interactions: In vivo and in vitro effect of shenmai injection, a herbal preparation, on the metabolic activities of hepatic cytochrome P450 3A1/2, 2C6, 1A2, and 2E1 in Rats. Planta Medica: natural products and medicinal plant research, 76 (3), 245-250. doi: 10.1055/s-0029-1186082

Herb-Drug interactions: In vivo and in vitro effect of shenmai injection, a herbal preparation, on the metabolic activities of hepatic cytochrome P450 3A1/2, 2C6, 1A2, and 2E1 in Rats

2009

Journal Article

Sulphonylurea physiochemical-pharmacokinetic relationships in the pancreas and liver

Fanning, Kent J., Anissimov, Yuri G. and Roberts, Michael S. (2009). Sulphonylurea physiochemical-pharmacokinetic relationships in the pancreas and liver. Journal of Pharmaceutical Sciences, 98 (8), 2807-2821. doi: 10.1002/jps.21631

Sulphonylurea physiochemical-pharmacokinetic relationships in the pancreas and liver

2009

Journal Article

Skin solubility determines maximum transepidermal flux for similar size molecules

Zhang, Qian, Grice, Jeffrey E., Li, Peng, Jepps, Owen G., Wang, Guang-Ji and Roberts, Michael S. (2009). Skin solubility determines maximum transepidermal flux for similar size molecules. Pharmaceutical Research, 26 (8), 1974-1985. doi: 10.1007/s11095-009-9912-4

Skin solubility determines maximum transepidermal flux for similar size molecules

2009

Journal Article

Liver transporters in hepatic drug disposition: An update

Li, Peng, Wang, Guang-Ji, Robertson, Thomas A. and Roberts, Michael S. (2009). Liver transporters in hepatic drug disposition: An update. Current Drug Metabolism, 10 (5), 482-498. doi: 10.2174/138920009788898037

Liver transporters in hepatic drug disposition: An update

2009

Journal Article

Molecular mechanism of recombinant liver fatty acid binding protein's antioxidant activity

Yan, J., Gong, Y. W., She, Y. M., Wang, G. Q., Roberts, M. S. and Burczynski, F. J. (2009). Molecular mechanism of recombinant liver fatty acid binding protein's antioxidant activity. Journal of Lipid Research, 50 (12), 2445-2454. doi: 10.1194/jlr.M900177-JLR200

Molecular mechanism of recombinant liver fatty acid binding protein's antioxidant activity

2009

Journal Article

Influence of perfusate composition on drug disposition in the in-situ perfused rat lung

Liu, X., Wang, J. Y., Khlentzos, A. M., Fontaine, F., Nikolovski, J., Goh, L.- A. and Roberts, M. S. (2009). Influence of perfusate composition on drug disposition in the in-situ perfused rat lung. International Journal of Pharmaceutics, 382 (1-2), 192-197. doi: 10.1016/j.ijpharm.2009.08.028

Influence of perfusate composition on drug disposition in the in-situ perfused rat lung

2009

Journal Article

Acute human self-poisoning with imidacloprid compound: A neonicotinoid insecticide

Mohamed, Fahim, Gawarammana, Indika, Robertson, Thomas A., Roberts, Michael S., Palangasinghem, Chathura, Zawahir, Shukry, Jayamanne, Shaluka, Kandasamy, Jaganathan, Eddleston, Michael, Buckley, Nick A., Dawson, Andrew H and Roberts, Darren M. (2009). Acute human self-poisoning with imidacloprid compound: A neonicotinoid insecticide. PLoS One, 4 (4) e5127, 1-5. doi: 10.1371/journal.pone.0005127

Acute human self-poisoning with imidacloprid compound: A neonicotinoid insecticide

2009

Journal Article

A preliminary study of atorvastatin plasma concentrations in critically ill patients with sepsis

Kruger, Peter S., Freir, Noelle M., Venkatesh, Bala, Robertson, Thomas A, Roberts, Michael S. and Jones, Mark (2009). A preliminary study of atorvastatin plasma concentrations in critically ill patients with sepsis. Intensive Care Medicine, 35 (4), 717-721. doi: 10.1007/s00134-008-1358-3

A preliminary study of atorvastatin plasma concentrations in critically ill patients with sepsis

2009

Journal Article

Piperacillin penetration into tissue of critically ill patients with sepsis - Bolus versus continuous administration?

Roberts, Jason A., Roberts, Michael S., Robertson, Thomas A., Dalley, Andrew J. and Lipman, Jeffrey (2009). Piperacillin penetration into tissue of critically ill patients with sepsis - Bolus versus continuous administration?. Critical Care Medicine, 37 (3), 926-933. doi: 10.1097/CCM.0b013e3181968e44

Piperacillin penetration into tissue of critically ill patients with sepsis - Bolus versus continuous administration?

2009

Journal Article

Cutaneous metabolism in transdermal drug delivery

Zhang, Qian, Grice, Jeffrey E., Wang, Guangji and Roberts, Michael S. (2009). Cutaneous metabolism in transdermal drug delivery. Current Drug Metabolism, 10 (3), 227-235. doi: 10.2174/138920009787846350

Cutaneous metabolism in transdermal drug delivery

2009

Journal Article

Diffusion modelling of percutaneous absorption kinetics: 4. Effects of a slow equilibration process within stratum corneum on absorption and desorption kinetics

Anissimov, Y. and Roberts, M. S. (2009). Diffusion modelling of percutaneous absorption kinetics: 4. Effects of a slow equilibration process within stratum corneum on absorption and desorption kinetics. Journal of Pharmaceutical Sciences, 98 (2), 772-781. doi: 10.1002/jps.21461

Diffusion modelling of percutaneous absorption kinetics: 4. Effects of a slow equilibration process within stratum corneum on absorption and desorption kinetics

2009

Journal Article

Computational strategies unravel and trace how liver disease changes hepatic drug disposition

Park, Sunwoo, Ropella, Glen E. P., Kim, Sean H. J., Roberts, Michael S. and Hunt, C. Anthony (2009). Computational strategies unravel and trace how liver disease changes hepatic drug disposition. Journal of Pharmacology and Experimental Therapeutics, 328 (1), 294-305. doi: 10.1124/jpet.108.142497

Computational strategies unravel and trace how liver disease changes hepatic drug disposition

2009

Journal Article

Assessment of Feasibility of Maillard Reaction between Baclofen and Lactose by Liquid Chromatography and Tandem Mass Spectrometry, Application to Pre Formulation Studies

Monajjemzadeh, F., Hassanzadeh, D., Valizadeh, H, Siahi-Shadbad, M. R., Mojarrad, J. S., Robertson, T. and Roberts, MS (2009). Assessment of Feasibility of Maillard Reaction between Baclofen and Lactose by Liquid Chromatography and Tandem Mass Spectrometry, Application to Pre Formulation Studies. AAPS PHARMSCITECH, 10 (2), 649-659. doi: 10.1208/s12249-009-9248-8

Assessment of Feasibility of Maillard Reaction between Baclofen and Lactose by Liquid Chromatography and Tandem Mass Spectrometry, Application to Pre Formulation Studies

2009

Journal Article

Measurement of tissue cortisol levels in patients with severe burns: a preliminary investigation

Cohen, Jeremy, Deans, Renae, Dalley, Andrew, Lipman, Jeff, Roberts, Michael S. and Venkatesh, Bala (2009). Measurement of tissue cortisol levels in patients with severe burns: a preliminary investigation. Critical Care, 13 (6) R189, xx-xx. doi: 10.1186/cc8184

Measurement of tissue cortisol levels in patients with severe burns: a preliminary investigation

2009

Journal Article

Unbound Cephalothin Pharmacokinetics in Adult Burn Patients Are Related to the Elapsed Time after Injury

Dalley, Andrew J., Deans, Renae, Lipman, Jeffrey, Venkatesh, Bala, Rudd, Michael, Roberts, Michael S. and Cross, Sheree E. (2009). Unbound Cephalothin Pharmacokinetics in Adult Burn Patients Are Related to the Elapsed Time after Injury. Antimicrobial Agents and Chemotherapy, 53 (12), 5303-5305. doi: 10.1128/AAC.01600-08

Unbound Cephalothin Pharmacokinetics in Adult Burn Patients Are Related to the Elapsed Time after Injury

2009

Journal Article

Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution

Roberts, Jason A., Kirkpatrick, Carl M. J., Roberts, Michael S., Robertson, Thomas A., Dalley, Andrew J. and Lipman, Jeffrey (2009). Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution. Journal of Antimicrobial Chemotherapy, 64 (1), 142-150. doi: 10.1093/jac/dkp139

Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution

2009

Journal Article

Interventions that can reduce inappropriate prescribing in the elderly: A systematic review

Kaur, S., Mitchell, G., Vitetta, L. and Roberts, M.S. (2009). Interventions that can reduce inappropriate prescribing in the elderly: A systematic review. Drugs & Ageing, 26 (12), 1013-1028. doi: 10.2165/11318890-000000000-00000

Interventions that can reduce inappropriate prescribing in the elderly: A systematic review

2008

Journal Article

In vitro and in vivo imaging of xenobiotic transport in human skin and in the rat liver

Roberts, Michael S., Roberts, Matthew J., Robertson, Thomas A., Sanchez, Washington, Thorling, Camilla, Zou, Yuhong, Zhao, Xin, Becker, Wolfgang and Zvyagin, Andrei V. (2008). In vitro and in vivo imaging of xenobiotic transport in human skin and in the rat liver. Journal of Biophotonics, 1 (6), 478-493. doi: 10.1002/jbio.200810058

In vitro and in vivo imaging of xenobiotic transport in human skin and in the rat liver