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2026

Journal Article

Limb Disuse Trials in Humans: Key Insights on Study Design, Ethics, and Project Execution

Stock, Matt S., Harmon, Kylie K., Andrushko, Justin W., Farthing, Jonathan P., Roberts, Michael D., Clark, Brian C., Ploutz-Snyder, Lori, Suetta, Charlotte, Wingfield, Harry C. S., van Loon, Luc J. C. and Carr, Joshua C. (2026). Limb Disuse Trials in Humans: Key Insights on Study Design, Ethics, and Project Execution. Exercise and Sport Sciences Reviews, 54 (4), 167-182. doi: 10.1249/JES.0000000000000392

Limb Disuse Trials in Humans: Key Insights on Study Design, Ethics, and Project Execution

2026

Journal Article

Physiological determinants of piperacillin and cefazolin clearance in septic and trauma patients

Ulldemolins, Marta, Abdul-Aziz, Mohd Hafiz, Hernández-Mitre, María Patricia, Mohd Sazlly Lim, Sazlyna, Udy, Andrew A., Colmenero, Manuel, Kruger, Peter, Kirkpatrick, Carl M. J., Roberts, Michael S., Wallis, Steven C., Paterson, David L., Lipman, Jeffrey and Roberts, Jason A. (2026). Physiological determinants of piperacillin and cefazolin clearance in septic and trauma patients. Critical Care. doi: 10.1186/s13054-026-06239-8

Physiological determinants of piperacillin and cefazolin clearance in septic and trauma patients

2026

Journal Article

Mesenchymal stem cell-derived liver-on-a-chip reconstitutes human liver structure and function

Brooks, Anastasia, Yang, Haotian, Barkauskas, Deborah S., Ranaweera, Supun, Zou, Da, Goh, Sally, Ruan, Qi, Bridle, Kim, Crawford, Darrell H.G., Liu, Xin, Roberts, Michael S., Doran, Michael R., Liang, Xiaowen, Zhao, Chun-Xia and Wang, Haolu (2026). Mesenchymal stem cell-derived liver-on-a-chip reconstitutes human liver structure and function. Cell Reports Methods 101545, 101545-101545. doi: 10.1016/j.crmeth.2026.101545

Mesenchymal stem cell-derived liver-on-a-chip reconstitutes human liver structure and function

2026

Journal Article

Multiphoton tomography of micro- and nanocosmetics in human skin: in vivo studies in volunteers and patients with ex vivo validation

Machado, Ana Carolina Henriques Ribeiro, Mohammed, Yousuf, Roberts, Michael S. and Leite-Silva, Vania Rodrigues (2026). Multiphoton tomography of micro- and nanocosmetics in human skin: in vivo studies in volunteers and patients with ex vivo validation. Skin Pharmacology and Physiology, 1-24. doi: 10.1159/000553032

Multiphoton tomography of micro- and nanocosmetics in human skin: in vivo studies in volunteers and patients with ex vivo validation

2025

Journal Article

Mechanistic modelling of lidocaine and prilocaine absorption from EMLA cream upon topical application using physiologically based pharmacokinetic modelling

Telaprolu, Krishna C., Tsakalozou, Eleftheria, Ghosh, Priyanka, Alam, Khondoker, Grice, Jeffrey E., Roberts, Michael S., Jamei, Masoud, Polak, Sebastian and Clarke, James F. (2025). Mechanistic modelling of lidocaine and prilocaine absorption from EMLA cream upon topical application using physiologically based pharmacokinetic modelling. AAPS PharmSciTech, 27 (1) 56. doi: 10.1208/s12249-025-03232-2

Mechanistic modelling of lidocaine and prilocaine absorption from EMLA cream upon topical application using physiologically based pharmacokinetic modelling

2025

Journal Article

Meropenem and piperacillin/tazobactam optimised dosing regimens for critically ill patients receiving renal replacement therapy

Roberts, Jason A., Ulldemolins, Marta, Liu, Xin, Baptista, João P., Bilgrami, Irma, Boidin, Clement, Brinkmann, Alexander, Castro, Pedro, Choi, Gordon, Cole, Louise, De Waele, Jan J., Deans, Renae, Donnellan, Sine, Eastwood, Glenn M., Frey, Otto R., Goutelle, Sylvain, Gresham, Rebecca, Jamal, Janattul Ain, Joynt, Gavin M., Kanji, Salmaan, Kluge, Stefan, König, Christina, Koulouras, Vasilios P., Lassig-Smith, Melissa, Laterre, Pierre-Francois, Lee, Anna, Lefrant, Jean-Yves, Lei, Katie, Leung, Patricia ... Young, Helen (2025). Meropenem and piperacillin/tazobactam optimised dosing regimens for critically ill patients receiving renal replacement therapy. Intensive Care Medicine, 51 (9), 1628-1640. doi: 10.1007/s00134-025-08067-w

Meropenem and piperacillin/tazobactam optimised dosing regimens for critically ill patients receiving renal replacement therapy

2025

Journal Article

Loperamide-induced severe cardiotoxicity: a toxicokinetic and toxicodynamic analysis derived from a case series and the published literature

Nic Ionmhain, Úna, Chiew, Angela L., Tierney, Michael, Al Ahmad, Judy, Pidcock, Stefanie, Whan, Faye Titania, Mackenzie, Lorraine, Roberts, Michael S. and Roberts, Darren M. (2025). Loperamide-induced severe cardiotoxicity: a toxicokinetic and toxicodynamic analysis derived from a case series and the published literature. Clinical Toxicology, 63 (4), 226-235. doi: 10.1080/15563650.2025.2459763

Loperamide-induced severe cardiotoxicity: a toxicokinetic and toxicodynamic analysis derived from a case series and the published literature

2025

Journal Article

Nephrotoxicity biomarkers following propanil (3,4-dichloropropionanilide) self-poisoning

Shihana, Fathima, Wijerathna, Thilini Madushanka, Gawarammana, Indika Bandara, Shahmy, Seyed, Chathuranga, Umesh, Palangasinghe, Chathura, Mostafa, Ahmed, Mackenzie, Lorraine, Roberts, Michael S., Buckley, Nicholas A. and Mohamed, Fahim (2025). Nephrotoxicity biomarkers following propanil (3,4-dichloropropionanilide) self-poisoning. Clinical Toxicology, 63 (4), 236-245. doi: 10.1080/15563650.2025.2457515

Nephrotoxicity biomarkers following propanil (3,4-dichloropropionanilide) self-poisoning

2025

Journal Article

Quantitative structure permeability relationships for phenolic compounds applied to human epidermal membranes in various solvents

Roberts, Michael S., Zhang, Qian, Mackenzie, Lorraine and Medley, Gregory A. (2025). Quantitative structure permeability relationships for phenolic compounds applied to human epidermal membranes in various solvents. European Journal of Pharmaceutical Sciences, 204 106914, 1-13. doi: 10.1016/j.ejps.2024.106914

Quantitative structure permeability relationships for phenolic compounds applied to human epidermal membranes in various solvents

2025

Journal Article

A prospective study of acute propranolol overdose defining dose thresholds of severe toxicity (ATOM – 9)

Isoardi, Katherine Z., Chiew, Angela L., Do, Cuong, Humphreys, Michael, Mustafa, Ahmead, Roberts, Michael S. and Isbister, Geoffrey K. (2025). A prospective study of acute propranolol overdose defining dose thresholds of severe toxicity (ATOM – 9). Clinical Toxicology, 63 (1), 1-9. doi: 10.1080/15563650.2024.2435397

A prospective study of acute propranolol overdose defining dose thresholds of severe toxicity (ATOM – 9)

2025

Book Chapter

Dermatological product sensorial properties: bridging pharmaceutical and therapeutic equivalence

Phan, Khanh, Leite-Silva, Vânia R., Prakash, Sangeeta, Namjoshi, Sarika, Panchal, Bhavesh, Roberts, Michael and Mohammed, Yousuf (2025). Dermatological product sensorial properties: bridging pharmaceutical and therapeutic equivalence. Topical products and dermal drug delivery. (pp. 223-240) Cham, Switzerland: Springer. doi: 10.1007/978-3-031-80525-7_9

Dermatological product sensorial properties: bridging pharmaceutical and therapeutic equivalence

2024

Journal Article

Effect of “in use” administration on topical product metamorphosis and skin permeation of Acyclovir creams: implications for bioequivalence

Namjoshi, Sarika N., Telaprolu, K. C., Grice, Jeffrey E., Benson, Heather A. E., Raney, S. G., Roberts, Michael S. and Mohammed, Yousuf H. (2024). Effect of “in use” administration on topical product metamorphosis and skin permeation of Acyclovir creams: implications for bioequivalence. Pharmaceutical Research, 41 (12) e79, 2391-2401. doi: 10.1007/s11095-024-03797-w

Effect of “in use” administration on topical product metamorphosis and skin permeation of Acyclovir creams: implications for bioequivalence

2024

Journal Article

STING nanoagonist boosts antitumor immunity of therapeutic DNA vaccines

Jia, Wencong, Chandra, Janin, Teoh, Siok Min, Tolley, Lynn, Yang, Haotian, Tse, Brian W. C., Sokolowski, Kamil A., Liang, Xiaowen, Crawford, Darrell H. G., Steel, Jason C., Yu, Chengzhong, Roberts, Michael S., Frazer, Ian H., Chen, Yu, Wang, Haolu and Yu, Meihua (2024). STING nanoagonist boosts antitumor immunity of therapeutic DNA vaccines. Nano Letters, 24 (49), 1-10. doi: 10.1021/acs.nanolett.4c03846

STING nanoagonist boosts antitumor immunity of therapeutic DNA vaccines

2024

Journal Article

Impact of different packaging configurations on a topical cream product

Mohammed, Yousuf H., Namjoshi, S. N., Telaprolu, K. C., Jung, N., Shewan, H. M., Stokes, J. R., Benson, H. A. E., Grice, J. E., Raney, S. G., Rantou, E., Windbergs, Maike and Roberts, Michael S. (2024). Impact of different packaging configurations on a topical cream product. Pharmaceutical Research, 41 (10), 2043-2056. doi: 10.1007/s11095-024-03772-5

Impact of different packaging configurations on a topical cream product

2024

Journal Article

Fludrocortisone dose–response relationship in septic shock: a randomised phase II trial

Walsham, James, Hammond, Naomi, Blumenthal, Antje, Cohen, Jeremy, Myburgh, John, Finfer, Simon, Evans, David, Peake, Sandra, Kruger, Peter, McCullough, James, Johnk, Loki, Ghelani, Dhaval, Billot, Laurent, Shan, Sana, Meyer, Jason, Rajbhandari, Dorrilyn, Koch, Carolyn, Bellomo, Rinaldo, Burrell, Louise M., Young, Morag, Roberts, Michael, Mackenzie, Lorraine, Medley, Gregory, Dalton, Joshua and Venkatesh, Balasubramanian (2024). Fludrocortisone dose–response relationship in septic shock: a randomised phase II trial. Intensive Care Medicine, 50 (12), 2050-2060. doi: 10.1007/s00134-024-07616-z

Fludrocortisone dose–response relationship in septic shock: a randomised phase II trial

2024

Journal Article

Topical semisolid drug product critical quality attributes with relevance to cutaneous bioavailability and pharmacokinetics: part 1—bioequivalence of acyclovir topical creams

Mohammed, Y. H., Namjoshi, S. N., Jung, N., Windbergs, M., Benson, H. A. E., Grice, J. E., Raney, S. G. and Roberts, M. S. (2024). Topical semisolid drug product critical quality attributes with relevance to cutaneous bioavailability and pharmacokinetics: part 1—bioequivalence of acyclovir topical creams. Pharmaceutical Research, 41 (7), 1507-1520. doi: 10.1007/s11095-024-03736-9

Topical semisolid drug product critical quality attributes with relevance to cutaneous bioavailability and pharmacokinetics: part 1—bioequivalence of acyclovir topical creams

2024

Journal Article

Identification and characterization of TM4SF1+ tumor self-seeded cells

Yang, Haotian, Wang, Haolu, He, Yaowu, Yang, Yang, Thompson, Erik W., Xia, Di, Burke, Leslie J., Cao, Lu, Hooper, John D., Roberts, Michael S., Crawford, Darrell H.G. and Liang, Xiaowen (2024). Identification and characterization of TM4SF1+ tumor self-seeded cells. Cell Reports, 43 (7) 114512, 1-24. doi: 10.1016/j.celrep.2024.114512

Identification and characterization of TM4SF1+ tumor self-seeded cells

2024

Journal Article

Multiple topical product dermatitis: paradigms in understanding and future perspectives

Mangion, Sean E., Mikkonen, Antti, Mackenzie, Lorraine, Roberts, Michael S. and Maibach, Howard I. (2024). Multiple topical product dermatitis: paradigms in understanding and future perspectives. JEADV Clinical Practice, 3 (1), 49-64. doi: 10.1002/jvc2.293

Multiple topical product dermatitis: paradigms in understanding and future perspectives

2024

Journal Article

Clinical toxicology of acute glyphosate self-poisoning: impact of plasma concentrations of glyphosate, its metabolite and polyethoxylated tallow amine surfactants on the toxicity

Qiang, Shuping, Mohamed, Fahim, Raubenheimer, Jacques, Buckley, Nicholas A., Roberts, Michael S. and Mackenzie, Lorraine (2024). Clinical toxicology of acute glyphosate self-poisoning: impact of plasma concentrations of glyphosate, its metabolite and polyethoxylated tallow amine surfactants on the toxicity. Clinical Toxicology, 62 (8), 483-496. doi: 10.1080/15563650.2024.2375584

Clinical toxicology of acute glyphosate self-poisoning: impact of plasma concentrations of glyphosate, its metabolite and polyethoxylated tallow amine surfactants on the toxicity

2023

Journal Article

RAAD: LIGHT-1 CubeSat's payload for the detection of terrestrial gamma-ray flashes

Di Giovanni, A., Arneodo, F., Al Qasim, A., Alblooshi, H., Alkhouri, F., Alkindi, L., Almannei, A., Almarri, N. H., Benabderrahmane, M. L., Bruno, G., Conicella, V., Fawwaz, O., Franchi, G., Kalos, S., Oikonomou, P., Perillo, L., Pittori, C., Roberts, M. S. and Torres, R. (2023). RAAD: LIGHT-1 CubeSat's payload for the detection of terrestrial gamma-ray flashes. Journal of Instrumentation, 18 (10) P10024, 1-20. doi: 10.1088/1748-0221/18/10/P10024

RAAD: LIGHT-1 CubeSat's payload for the detection of terrestrial gamma-ray flashes