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2025

Journal Article

Quantitative structure permeability relationships for phenolic compounds applied to human epidermal membranes in various solvents

Roberts, Michael S., Zhang, Qian, Mackenzie, Lorraine and Medley, Gregory A. (2025). Quantitative structure permeability relationships for phenolic compounds applied to human epidermal membranes in various solvents. European Journal of Pharmaceutical Sciences, 204 106914, 106914. doi: 10.1016/j.ejps.2024.106914

Quantitative structure permeability relationships for phenolic compounds applied to human epidermal membranes in various solvents

2024

Journal Article

Identification and characterization of TM4SF1+ tumor self-seeded cells

Yang, Haotian, Wang, Haolu, He, Yaowu, Yang, Yang, Thompson, Erik W., Xia, Di, Burke, Leslie J., Cao, Lu, Hooper, John D., Roberts, Michael S., Crawford, Darrell H.G. and Liang, Xiaowen (2024). Identification and characterization of TM4SF1+ tumor self-seeded cells. Cell Reports, 43 (7) 114512. doi: 10.1016/j.celrep.2024.114512

Identification and characterization of TM4SF1+ tumor self-seeded cells

2024

Journal Article

Multiple topical product dermatitis: paradigms in understanding and future perspectives

Mangion, Sean E., Mikkonen, Antti, Mackenzie, Lorraine, Roberts, Michael S. and Maibach, Howard I. (2024). Multiple topical product dermatitis: paradigms in understanding and future perspectives. JEADV Clinical Practice, 3 (1), 49-64. doi: 10.1002/jvc2.293

Multiple topical product dermatitis: paradigms in understanding and future perspectives

2024

Journal Article

Clinical toxicology of acute glyphosate self-poisoning: impact of plasma concentrations of glyphosate, its metabolite and polyethoxylated tallow amine surfactants on the toxicity

Qiang, Shuping, Mohamed, Fahim, Raubenheimer, Jacques, Buckley, Nicholas A., Roberts, Michael S. and Mackenzie, Lorraine (2024). Clinical toxicology of acute glyphosate self-poisoning: impact of plasma concentrations of glyphosate, its metabolite and polyethoxylated tallow amine surfactants on the toxicity. Clinical Toxicology, 62 (8), 483-496. doi: 10.1080/15563650.2024.2375584

Clinical toxicology of acute glyphosate self-poisoning: impact of plasma concentrations of glyphosate, its metabolite and polyethoxylated tallow amine surfactants on the toxicity

2023

Journal Article

Dynamic exposure and body burden models for per- and polyfluoroalkyl substances (PFAS) enable management of food safety risks in cattle

Mikkonen, Antti T., Martin, Jennifer, Upton, Richard N., Moenning, Jan-Louis, Numata, Jorge, Taylor, Mark P., Roberts, Michael S. and Mackenzie, Lorraine (2023). Dynamic exposure and body burden models for per- and polyfluoroalkyl substances (PFAS) enable management of food safety risks in cattle. Environment International, 180 108218. doi: 10.1016/j.envint.2023.108218

Dynamic exposure and body burden models for per- and polyfluoroalkyl substances (PFAS) enable management of food safety risks in cattle

2023

Journal Article

Human skin drug metabolism: relationships between methyl salicylate metabolism and esterase activities in IVPT skin membranes

Telaprolu, Krishna C., Grice, Jeffrey E., Mohammed, Yousuf H. and Roberts, Michael S. (2023). Human skin drug metabolism: relationships between methyl salicylate metabolism and esterase activities in IVPT skin membranes. Metabolites, 13 (8) 934, 1-12. doi: 10.3390/metabo13080934

Human skin drug metabolism: relationships between methyl salicylate metabolism and esterase activities in IVPT skin membranes

2023

Journal Article

Spatio-temporal trends in livestock exposure to per- and polyfluoroalkyl substances (PFAS) inform risk assessment and management measures

Mikkonen, Antti T., Martin, Jennifer, Upton, Richard N., Barker, Andrew O., Brumley, Carolyn M., Taylor, Mark P., Mackenzie, Lorraine and Roberts, Michael S. (2023). Spatio-temporal trends in livestock exposure to per- and polyfluoroalkyl substances (PFAS) inform risk assessment and management measures. Environmental Research, 225 115518, 1-14. doi: 10.1016/j.envres.2023.115518

Spatio-temporal trends in livestock exposure to per- and polyfluoroalkyl substances (PFAS) inform risk assessment and management measures

2023

Journal Article

Seborrheic dermatitis: topical therapeutics and formulation design

Mangion, Sean E., Mackenzie, Lorraine, Roberts, Michael S. and Holmes, Amy M. (2023). Seborrheic dermatitis: topical therapeutics and formulation design. European Journal of Pharmaceutics and Biopharmaceutics, 185, 148-164. doi: 10.1016/j.ejpb.2023.01.023

Seborrheic dermatitis: topical therapeutics and formulation design

2023

Journal Article

Rapid determination of polyethoxylated tallow amine surfactants in human plasma by LC-MSMS

Qiang, Shuping, Mohamed, Fahim, Mackenzie, Lorraine and Roberts, Michael S. (2023). Rapid determination of polyethoxylated tallow amine surfactants in human plasma by LC-MSMS. Talanta, 254 124115, 1-12. doi: 10.1016/j.talanta.2022.124115

Rapid determination of polyethoxylated tallow amine surfactants in human plasma by LC-MSMS

2023

Journal Article

A thermodynamic and kinetic analysis of human epidermal penetration of phenolic compounds: II. Maximum flux and solute diffusion through stratum corneum lipids

Zhang, Qian, Alinaghi, Azadeh, Williams, Desmond B. and Roberts, Michael S. (2023). A thermodynamic and kinetic analysis of human epidermal penetration of phenolic compounds: II. Maximum flux and solute diffusion through stratum corneum lipids. International Journal of Pharmaceutics, 631 122522, 1-11. doi: 10.1016/j.ijpharm.2022.122522

A thermodynamic and kinetic analysis of human epidermal penetration of phenolic compounds: II. Maximum flux and solute diffusion through stratum corneum lipids

2023

Journal Article

Thermodynamic and kinetic analysis of human epidermal penetration of phenolic compounds: I. Stratum corneum solubility and partitioning

Alinaghi, Azadeh, Zhang, Qian, Williams, Desmond B., Mackenzie, Lorraine and Roberts, Michael S. (2023). Thermodynamic and kinetic analysis of human epidermal penetration of phenolic compounds: I. Stratum corneum solubility and partitioning. International Journal of Pharmaceutics, 630 122424, 1-10. doi: 10.1016/j.ijpharm.2022.122424

Thermodynamic and kinetic analysis of human epidermal penetration of phenolic compounds: I. Stratum corneum solubility and partitioning

2023

Journal Article

In vitro screening of topical formulation excipients for epithelial toxicity in cancerous and non-cancerous cell lines

Forouz, Farzaneh, Mohammed, Yousuf, Nejad, Hamid S. A. Shobeiri, Roberts, Michael S. and Grice, Jeffrey E. (2023). In vitro screening of topical formulation excipients for epithelial toxicity in cancerous and non-cancerous cell lines. EXCLI Journal, 22, 1173-1199. doi: 10.17179/excli2023-6072

In vitro screening of topical formulation excipients for epithelial toxicity in cancerous and non-cancerous cell lines

2022

Journal Article

Nanoparticle elasticity regulates the formation of cell membrane-coated nanoparticles and their nano-bio interactions

Zou, Da, Wu, Zeming, Yi, Xin, Hui, Yue, Yang, Guangze, Liu, Yun, Tengjisi,, Wang, Haofei, Brooks, Anastasia, Wang, Haolu, Liu, Xin, Xu, Zhi Ping, Roberts, Michael S., Gao, Huajian and Zhao, Chun-Xia (2022). Nanoparticle elasticity regulates the formation of cell membrane-coated nanoparticles and their nano-bio interactions. Proceedings of the National Academy of Sciences, 120 (1) e2214757120, e2214757120. doi: 10.1073/pnas.2214757120

Nanoparticle elasticity regulates the formation of cell membrane-coated nanoparticles and their nano-bio interactions

2022

Journal Article

Percutaneous absorption of steroids from finite doses: predicting urinary excretion from in vitro skin permeation testing

Liu, Xin, Cheruvu, Hanumanth S., Anissimov, Yuri G., van der Hoek, John, Tsakalozou, Eleftheria, Ni, Zhanglin, Ghosh, Priyanka, Grice, Jeffrey E. and Roberts, Michael S. (2022). Percutaneous absorption of steroids from finite doses: predicting urinary excretion from in vitro skin permeation testing. International Journal of Pharmaceutics, 625 122095, 1-16. doi: 10.1016/j.ijpharm.2022.122095

Percutaneous absorption of steroids from finite doses: predicting urinary excretion from in vitro skin permeation testing

2022

Journal Article

Mechanistic modeling of in vitro skin permeation and extrapolation to in vivo for topically applied metronidazole drug products using a physiologically based pharmacokinetic model

Arora, Sumit, Clarke, James, Tsakalozou, Eleftheria, Ghosh, Priyanka, Alam, Khondoker, Grice, Jeffery E., Roberts, Michael S., Jamei, Masoud and Polak, Sebastian (2022). Mechanistic modeling of in vitro skin permeation and extrapolation to in vivo for topically applied metronidazole drug products using a physiologically based pharmacokinetic model. Molecular Pharmaceutics, 19 (9), 3139-3152. doi: 10.1021/acs.molpharmaceut.2c00229

Mechanistic modeling of in vitro skin permeation and extrapolation to in vivo for topically applied metronidazole drug products using a physiologically based pharmacokinetic model

2022

Journal Article

Compartmental modeling of skin absorption and desorption kinetics: Donor solvent evaporation, variable diffusion/partition coefficients, and slow equilibration process within stratum corneum

Amarah, A. A., Hadgraft, J., Roberts, M. S. and Anissimov, Y. G. (2022). Compartmental modeling of skin absorption and desorption kinetics: Donor solvent evaporation, variable diffusion/partition coefficients, and slow equilibration process within stratum corneum. International Journal of Pharmaceutics, 623 121902, 1-10. doi: 10.1016/j.ijpharm.2022.121902

Compartmental modeling of skin absorption and desorption kinetics: Donor solvent evaporation, variable diffusion/partition coefficients, and slow equilibration process within stratum corneum

2022

Journal Article

Advances and future perspectives in epithelial drug delivery

Mohammed, Yousuf, Holmes, Amy, Kwok, Philip Chi Lip, Kumeria, Tushar, Namjoshi, Sarika, Imran, Mohammad, Matteucci, Lana, Ali, Masood, Tai, Waiting, Benson, Heather A.E. and Roberts, Michael S. (2022). Advances and future perspectives in epithelial drug delivery. Advanced Drug Delivery Reviews, 186 114293, 1-38. doi: 10.1016/j.addr.2022.114293

Advances and future perspectives in epithelial drug delivery

2022

Journal Article

An updated database of human maximum skin fluxes and epidermal permeability coefficients for drugs, xenobiotics, and other solutes applied as aqueous solutions

Cheruvu, Hanumanth Srikanth, Liu, Xin, Grice, Jeffrey E and Roberts, Michael S. (2022). An updated database of human maximum skin fluxes and epidermal permeability coefficients for drugs, xenobiotics, and other solutes applied as aqueous solutions. Data in Brief, 42 108242, 1-9. doi: 10.1016/j.dib.2022.108242

An updated database of human maximum skin fluxes and epidermal permeability coefficients for drugs, xenobiotics, and other solutes applied as aqueous solutions

2022

Journal Article

Multi-modal imaging to assess the follicular delivery of zinc pyrithione

Mangion, Sean E., Sandiford, Lydia, Mohammed, Yousuf, Roberts, Michael S. and Holmes, Amy M. (2022). Multi-modal imaging to assess the follicular delivery of zinc pyrithione. Pharmaceutics, 14 (5) 1076, 1-14. doi: 10.3390/pharmaceutics14051076

Multi-modal imaging to assess the follicular delivery of zinc pyrithione

2022

Journal Article

Population pharmacokinetic model for tramadol and O-desmethyltramadol in older patients

Al-Qurain, Aymen A., Upton, Richard N., Tadros, Rami, Roberts, Michael S. and Wiese, Michael D. (2022). Population pharmacokinetic model for tramadol and O-desmethyltramadol in older patients. European Journal of Drug Metabolism and Pharmacokinetics, 47 (3), 387-402. doi: 10.1007/s13318-022-00756-x

Population pharmacokinetic model for tramadol and O-desmethyltramadol in older patients