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2023

Journal Article

A thermodynamic and kinetic analysis of human epidermal penetration of phenolic compounds: II. Maximum flux and solute diffusion through stratum corneum lipids

Zhang, Qian, Alinaghi, Azadeh, Williams, Desmond B. and Roberts, Michael S. (2023). A thermodynamic and kinetic analysis of human epidermal penetration of phenolic compounds: II. Maximum flux and solute diffusion through stratum corneum lipids. International Journal of Pharmaceutics, 631 122522, 1-11. doi: 10.1016/j.ijpharm.2022.122522

A thermodynamic and kinetic analysis of human epidermal penetration of phenolic compounds: II. Maximum flux and solute diffusion through stratum corneum lipids

2023

Journal Article

High-resolution radio study of the dragonfly pulsar wind nebula powered by PSR J2021+3651

Jin, Ruolan, Ng, C. -Y., Roberts, Mallory S. E. and Li, Kwan-Lok (2023). High-resolution radio study of the dragonfly pulsar wind nebula powered by PSR J2021+3651. Astrophysical Journal, 942 (2) 100. doi: 10.3847/1538-4357/aca656

High-resolution radio study of the dragonfly pulsar wind nebula powered by PSR J2021+3651

2023

Journal Article

Thermodynamic and kinetic analysis of human epidermal penetration of phenolic compounds: I. Stratum corneum solubility and partitioning

Alinaghi, Azadeh, Zhang, Qian, Williams, Desmond B., Mackenzie, Lorraine and Roberts, Michael S. (2023). Thermodynamic and kinetic analysis of human epidermal penetration of phenolic compounds: I. Stratum corneum solubility and partitioning. International Journal of Pharmaceutics, 630 122424, 1-10. doi: 10.1016/j.ijpharm.2022.122424

Thermodynamic and kinetic analysis of human epidermal penetration of phenolic compounds: I. Stratum corneum solubility and partitioning

2023

Journal Article

In vitro screening of topical formulation excipients for epithelial toxicity in cancerous and non-cancerous cell lines

Forouz, Farzaneh, Mohammed, Yousuf, Nejad, Hamid S. A. Shobeiri, Roberts, Michael S. and Grice, Jeffrey E. (2023). In vitro screening of topical formulation excipients for epithelial toxicity in cancerous and non-cancerous cell lines. EXCLI Journal, 22, 1173-1199. doi: 10.17179/excli2023-6072

In vitro screening of topical formulation excipients for epithelial toxicity in cancerous and non-cancerous cell lines

2022

Journal Article

Nanoparticle elasticity regulates the formation of cell membrane-coated nanoparticles and their nano-bio interactions

Zou, Da, Wu, Zeming, Yi, Xin, Hui, Yue, Yang, Guangze, Liu, Yun, Tengjisi,, Wang, Haofei, Brooks, Anastasia, Wang, Haolu, Liu, Xin, Xu, Zhi Ping, Roberts, Michael S., Gao, Huajian and Zhao, Chun-Xia (2022). Nanoparticle elasticity regulates the formation of cell membrane-coated nanoparticles and their nano-bio interactions. Proceedings of the National Academy of Sciences, 120 (1) e2214757120, e2214757120. doi: 10.1073/pnas.2214757120

Nanoparticle elasticity regulates the formation of cell membrane-coated nanoparticles and their nano-bio interactions

2022

Journal Article

Human epidermal in vitro permeation test (IVPT) analyses of alcohols and steroids

Alinaghi, Azadeh, Macedo, Ana, Cheruvu, Hanumanth S., Holmes, Amy and Roberts, Michael S. (2022). Human epidermal in vitro permeation test (IVPT) analyses of alcohols and steroids. International Journal of Pharmaceutics, 627 122114, 1-18. doi: 10.1016/j.ijpharm.2022.122114

Human epidermal in vitro permeation test (IVPT) analyses of alcohols and steroids

2022

Journal Article

Percutaneous absorption of steroids from finite doses: predicting urinary excretion from in vitro skin permeation testing

Liu, Xin, Cheruvu, Hanumanth S., Anissimov, Yuri G., van der Hoek, John, Tsakalozou, Eleftheria, Ni, Zhanglin, Ghosh, Priyanka, Grice, Jeffrey E. and Roberts, Michael S. (2022). Percutaneous absorption of steroids from finite doses: predicting urinary excretion from in vitro skin permeation testing. International Journal of Pharmaceutics, 625 122095, 1-16. doi: 10.1016/j.ijpharm.2022.122095

Percutaneous absorption of steroids from finite doses: predicting urinary excretion from in vitro skin permeation testing

2022

Journal Article

Mechanistic modeling of in vitro skin permeation and extrapolation to in vivo for topically applied metronidazole drug products using a physiologically based pharmacokinetic model

Arora, Sumit, Clarke, James, Tsakalozou, Eleftheria, Ghosh, Priyanka, Alam, Khondoker, Grice, Jeffery E., Roberts, Michael S., Jamei, Masoud and Polak, Sebastian (2022). Mechanistic modeling of in vitro skin permeation and extrapolation to in vivo for topically applied metronidazole drug products using a physiologically based pharmacokinetic model. Molecular Pharmaceutics, 19 (9), 3139-3152. doi: 10.1021/acs.molpharmaceut.2c00229

Mechanistic modeling of in vitro skin permeation and extrapolation to in vivo for topically applied metronidazole drug products using a physiologically based pharmacokinetic model

2022

Journal Article

Compartmental modeling of skin absorption and desorption kinetics: Donor solvent evaporation, variable diffusion/partition coefficients, and slow equilibration process within stratum corneum

Amarah, A. A., Hadgraft, J., Roberts, M. S. and Anissimov, Y. G. (2022). Compartmental modeling of skin absorption and desorption kinetics: Donor solvent evaporation, variable diffusion/partition coefficients, and slow equilibration process within stratum corneum. International Journal of Pharmaceutics, 623 121902, 1-10. doi: 10.1016/j.ijpharm.2022.121902

Compartmental modeling of skin absorption and desorption kinetics: Donor solvent evaporation, variable diffusion/partition coefficients, and slow equilibration process within stratum corneum

2022

Journal Article

Advances and future perspectives in epithelial drug delivery

Mohammed, Yousuf, Holmes, Amy, Kwok, Philip Chi Lip, Kumeria, Tushar, Namjoshi, Sarika, Imran, Mohammad, Matteucci, Lana, Ali, Masood, Tai, Waiting, Benson, Heather A.E. and Roberts, Michael S. (2022). Advances and future perspectives in epithelial drug delivery. Advanced Drug Delivery Reviews, 186 114293, 1-38. doi: 10.1016/j.addr.2022.114293

Advances and future perspectives in epithelial drug delivery

2022

Journal Article

An updated database of human maximum skin fluxes and epidermal permeability coefficients for drugs, xenobiotics, and other solutes applied as aqueous solutions

Cheruvu, Hanumanth Srikanth, Liu, Xin, Grice, Jeffrey E and Roberts, Michael S. (2022). An updated database of human maximum skin fluxes and epidermal permeability coefficients for drugs, xenobiotics, and other solutes applied as aqueous solutions. Data in Brief, 42 108242, 1-9. doi: 10.1016/j.dib.2022.108242

An updated database of human maximum skin fluxes and epidermal permeability coefficients for drugs, xenobiotics, and other solutes applied as aqueous solutions

2022

Journal Article

Multi-modal imaging to assess the follicular delivery of zinc pyrithione

Mangion, Sean E., Sandiford, Lydia, Mohammed, Yousuf, Roberts, Michael S. and Holmes, Amy M. (2022). Multi-modal imaging to assess the follicular delivery of zinc pyrithione. Pharmaceutics, 14 (5) 1076, 1-14. doi: 10.3390/pharmaceutics14051076

Multi-modal imaging to assess the follicular delivery of zinc pyrithione

2022

Journal Article

Population pharmacokinetic model for tramadol and O-desmethyltramadol in older patients

Al-Qurain, Aymen A., Upton, Richard N., Tadros, Rami, Roberts, Michael S. and Wiese, Michael D. (2022). Population pharmacokinetic model for tramadol and O-desmethyltramadol in older patients. European Journal of Drug Metabolism and Pharmacokinetics, 47 (3), 387-402. doi: 10.1007/s13318-022-00756-x

Population pharmacokinetic model for tramadol and O-desmethyltramadol in older patients

2022

Journal Article

In Defense of Current Concepts and Applications of Clearance in Drug Development and Therapeutics

Rowland, Malcolm, Roberts, Michael S. and Pang, K Sandy (2022). In Defense of Current Concepts and Applications of Clearance in Drug Development and Therapeutics. Drug metabolism and disposition: the biological fate of chemicals, 50 (2), 187-190. doi: 10.1124/dmd.121.000637

In Defense of Current Concepts and Applications of Clearance in Drug Development and Therapeutics

2022

Book Chapter

Challenges and innovations of controlled drug delivery

Benson, Heather A.E. and Roberts, Michael S. (2022). Challenges and innovations of controlled drug delivery. Fundamentals of Drug Delivery. (pp. 3-14) edited by Heather A. E. Benson, Michael S. Roberts, Adrian C. Williams and Xiaowen Liang. Hoboken, NJ, United States: Wiley. doi: 10.1002/9781119769644.ch1

Challenges and innovations of controlled drug delivery

2022

Book Chapter

Theranostic nanoparticles for imaging and targeted drug delivery to the liver

Wang, Haolu, Yang, Haotian, Ruan, Qi, Roberts, Michael S. and Liang, Xiaowen (2022). Theranostic nanoparticles for imaging and targeted drug delivery to the liver. Fundamentals of drug delivery. (pp. 311-328) edited by Heather A. E. Benson, Michael S. Roberts, Adrian C. Williams and Xiaowen Liang. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/9781119769644.ch12

Theranostic nanoparticles for imaging and targeted drug delivery to the liver

2022

Journal Article

Application of confocal raman microscopy for the characterization of topical semisolid formulations and their penetration into human skin ex vivo

Jung, Nathalie, Namjoshi, Sarika, Mohammed, Yousuf, Grice, Jeffrey E., Benson, Heather A. E., Raney, Sam G., Roberts, Michael S. and Windbergs, Maike (2022). Application of confocal raman microscopy for the characterization of topical semisolid formulations and their penetration into human skin ex vivo. Pharmaceutical Research, 39 (5), 935-948. doi: 10.1007/s11095-022-03245-7

Application of confocal raman microscopy for the characterization of topical semisolid formulations and their penetration into human skin ex vivo

2022

Book

Oral drug delivery for modified release formulations

Edmund S. Kostewicz, Maria Vertzoni, Heather A. E. Benson and Michael S. Roberts eds. (2022). Oral drug delivery for modified release formulations. Hoboken, NJ, United States: John Wiley and Sons Inc.. doi: 10.1002/9781119772729

Oral drug delivery for modified release formulations

2022

Journal Article

Predicting viable skin concentration: modelling the subpapillary plexus

Calcutt, Joshua J., Roberts, Michael S. and Anissimov, Yuri G. (2022). Predicting viable skin concentration: modelling the subpapillary plexus. Pharmaceutical Research, 39 (4), 783-793. doi: 10.1007/s11095-022-03215-z

Predicting viable skin concentration: modelling the subpapillary plexus

2021

Journal Article

Human epidermal zinc concentrations after topical application of ZnO nanoparticles in sunscreens

Khabir, Zahra, Holmes, Amy M., Lai, Yi-Jen, Liang, Liuen, Deva, Anand, Polikarpov, Michael A., Roberts, Michael S. and Zvyagin, Andrei V. (2021). Human epidermal zinc concentrations after topical application of ZnO nanoparticles in sunscreens. International Journal of Molecular Sciences, 22 (22) 12372, 12372. doi: 10.3390/ijms222212372

Human epidermal zinc concentrations after topical application of ZnO nanoparticles in sunscreens