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2024

Conference Publication

Epithelial cancers demonstrate IL34-associated dysfunction of Langerhans cells

Dang, Thi Viet Trinh, Gillinder, Kevin R., Nguyen, Quan, Mulay, Onkar, Vo, Tuan, Mehdi, Ahmed M., Zhou, Chenhao, Brooks, Andrew J., Asplett, Kiran, Leggatt, Graham R., Hume, David A., Frazer, Ian H. and Chandra, Janin (2024). Epithelial cancers demonstrate IL34-associated dysfunction of Langerhans cells. AACR Special Conference in Cancer Research: Tumor Immunology and Immunotherapy, Boston, MA, United States, 18-21 October 2024. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/2326-6074.tumimm24-a001

Epithelial cancers demonstrate IL34-associated dysfunction of Langerhans cells

2023

Conference Publication

Age related neuropathology in a novel mouse model of Adult‐onset leukoencephalopathy

Shabestari, Sepideh Kiani, Radhakrishnan, Hamsi, Rothermich, Winston Chang, Capocchi, Joia Kai, Jullienne, Amandine, Nguyen, Jasmine, Tran, Kayla Nhi, Pascual, Jesse R., Martini, Alessandra Cadete, Head, Elizabeth, Hume, David A, Pridans, Clare, Obenaus, Andre, Stark, Craig E.L., Davtyan, Hayk and Blurton‐Jones, Mathew (2023). Age related neuropathology in a novel mouse model of Adult‐onset leukoencephalopathy. Alzheimer’s Association International Conference AAIC 2023, Amsterdam, Netherlands, 16-20 July 2023. Hoboken, NJ United States: John Wiley & Sons. doi: 10.1002/alz.070996

Age related neuropathology in a novel mouse model of Adult‐onset leukoencephalopathy

2023

Conference Publication

Transcriptomic signatures of antibacterial responses in the earliest lesions of Crohn's disease

Whiley, P., Summers, K., Pavli, P., Hume, D. and O'Brien, C. (2023). Transcriptomic signatures of antibacterial responses in the earliest lesions of Crohn's disease. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2023, Brisbane, QLD Australia, 2—5 September 2023. Richmond, VIC Australia: John Wiley and Sons.

Transcriptomic signatures of antibacterial responses in the earliest lesions of Crohn's disease

2023

Conference Publication

Mechanisms underlying the rescue of postnatal bone development in CSF1R-deficient rats following wild-type bone marrow cell transfer

Batoon, Lena, Keshvari, Sahar, Irvine, Katharine, Caruso, Melanie, Patkar, Omkar, Sehgal, Anuj, Millard, Susan, Hume, David and Pettit, Allison (2023). Mechanisms underlying the rescue of postnatal bone development in CSF1R-deficient rats following wild-type bone marrow cell transfer. 2022 Annual Meeting of the American Society for Bone and Mineral Research, Austin, TX, United States, 9-12 September 2022. Hoboken, NJ, United States: Wiley-Blackwell.

Mechanisms underlying the rescue of postnatal bone development in CSF1R-deficient rats following wild-type bone marrow cell transfer

2022

Conference Publication

Gene-therapy based modulation of antigen-presenting cells within hyperproliferative epithelium to restore immunity

Dang, T. V. T., Gillinder, K. G., Brooks, A. J., Asplett, K., Tolley, L. K., Hume, D. A., Leggatt, G. R., Frazer, I. H. and Chandra, J. (2022). Gene-therapy based modulation of antigen-presenting cells within hyperproliferative epithelium to restore immunity. 29th Annual Congress of the European-Society-of-Gene-and-Cell-Therapy (ESCGT), Edinburgh, United Kingdom, 11-14 October 2022. New Rochelle, NY United States: Mary Ann Liebert.

Gene-therapy based modulation of antigen-presenting cells within hyperproliferative epithelium to restore immunity

2022

Conference Publication

Appearances Can Be Deceiving: Macrophage Fragmentation Confounds Ex Vivo Haematopoietic Tissue Analysis

Pettit, Allison R., Batoon, Lena, Heng, Ostyn, Hume, David, Irvine, Kate, Kaur, Simranpreet, Levesque, Jean-Pierre, Magor, Graham, Millard, Susan, Noll, Jacqueline, Perkins, Andrew, Raggatt, Liza, Sandrock, Cheyenne, Sehgal, Anuj, Sester, David, Opperman, Khatora Shanae, Summers, Kim, Wu, Andy and Zannettino, Andrew (2022). Appearances Can Be Deceiving: Macrophage Fragmentation Confounds Ex Vivo Haematopoietic Tissue Analysis. 51st Annual Scientific Meeting of the ISEH - International Society for Experimental Hematology, Edinburgh, United Kingdom, 1-4 September 2022. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.exphem.2022.07.018

Appearances Can Be Deceiving: Macrophage Fragmentation Confounds Ex Vivo Haematopoietic Tissue Analysis

2020

Conference Publication

3092 – Stable colony stimulating factor 1 fusion protein treatment increases the hematopoietic stem cell pool and enhances their mobilization in mice

Kaur, Simranpreet, Sehgal, Anuj, Wu, Andy, Millard, Susan, Batoon, Lena, Sandrock, Cheyenne, Levesque, Jean-Pierre, Hume, David, Raggatt, Liza and Pettit, Allison (2020). 3092 – Stable colony stimulating factor 1 fusion protein treatment increases the hematopoietic stem cell pool and enhances their mobilization in mice. 49th Annual Scientific Meeting of the ISEH - International Society for Experimental Hematology, New York, NY USA, 20-23 August 2020. Philadelphia, PA USA: Elsevier. doi: 10.1016/j.exphem.2020.09.105

3092 – Stable colony stimulating factor 1 fusion protein treatment increases the hematopoietic stem cell pool and enhances their mobilization in mice

2018

Conference Publication

Macrophage colony stimulating factor (CSF1) promotes regression of advanced fibrosis and liver regeneration in mice

Irvine, Katharine, Genz, Berit, Clouston, Andrew D. and Hume, David (2018). Macrophage colony stimulating factor (CSF1) promotes regression of advanced fibrosis and liver regeneration in mice. Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting, San Francisco, CA USA, 9-13 November 2018. Hoboken, NJ USA: Wiley.

Macrophage colony stimulating factor (CSF1) promotes regression of advanced fibrosis and liver regeneration in mice

2018

Conference Publication

Self-repopulating recipient bone marrow recipient macrophages promote hematopoietic stem cell engraftment post autologous transplantation

Pettit, Allison, Kaur, Simranpreet, Raggatt, Liza, Millard, Susan, Wu, Andy, Batoon, Lena, Jacobsen, Rebecca, Winkler, Ingrid, MacDonald, Kelli, Perkins, Andrew, Hume, David and Levesque, Jean-Pierre (2018). Self-repopulating recipient bone marrow recipient macrophages promote hematopoietic stem cell engraftment post autologous transplantation. 47th Annual Scientific Meeting of the International Society for Experimental Hematology, Los Angeles, CA, United States, 23-26 August 2018. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2018.06.117

Self-repopulating recipient bone marrow recipient macrophages promote hematopoietic stem cell engraftment post autologous transplantation

2016

Conference Publication

Radio-resistant recipient bone marrow (BM) macrophages (Macs) are necessary for hematopoietic stem cell (HSC) engraftment post transplantation

Levesque, Jean-Pierre, Kaur, Simranpreet, Jacobsen, Rebecca, Millard, Susan, Batoon, Lena, Winkler, Ingrid, Macdonald, Kelli, Perkins, Andrew, Hume, David, Raggatt, Liza and Pettit, Allison (2016). Radio-resistant recipient bone marrow (BM) macrophages (Macs) are necessary for hematopoietic stem cell (HSC) engraftment post transplantation. 45th Annual Scientific Meeting of the ISEH – International Society for Experimental Hematology, San Diego, CA, United States, 25-28 August, 2016. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2016.06.049

Radio-resistant recipient bone marrow (BM) macrophages (Macs) are necessary for hematopoietic stem cell (HSC) engraftment post transplantation

2016

Conference Publication

Recipient bone marrow (BM) macrophages (Macs) are vital for haematopoietic stem cell (HSC) engraftment post autologous transplantation

Kaur, S., Raggatt, L. J., Jacobsen, R. N., Millard, S., Batoon, L., Winkler, I. G., Macdonald, K. P. A., Perkins, A. C., Hume, D. A., Levesque, J. P. and Pettit, A. R. (2016). Recipient bone marrow (BM) macrophages (Macs) are vital for haematopoietic stem cell (HSC) engraftment post autologous transplantation. International Congress of Immunology (ICI), Melbourne, VIC, Australia, 21-26 August 2016. Weinheim, Germany: Wiley - VCH. doi: 10.1002/eji.201670200

Recipient bone marrow (BM) macrophages (Macs) are vital for haematopoietic stem cell (HSC) engraftment post autologous transplantation

2016

Conference Publication

Evolution of cell death responses to cytosolic DNA

Vitak, N., Johnson, K. N., Hume, D. A., Sester, D. P. and Stacey, K. J. (2016). Evolution of cell death responses to cytosolic DNA. ICI 2016 International Congress of Immunology, Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200

Evolution of cell death responses to cytosolic DNA

2015

Conference Publication

Autologous Haematopotetic Stem Cell Transplantation Requires Recipient Bm Macrophages

Kaur, Simranpreet, Raggatt, Liza J., Jacobsen, Rebecca, Millard, Susan, Barbier, Valerie, Nowlan, Bianca, Winkler, Ingrid G., MacDonald, Kelli P., Perkins, Andrew C., Hume, David A., Levesque, Jean P. and Pettit, Allison R. (2015). Autologous Haematopotetic Stem Cell Transplantation Requires Recipient Bm Macrophages. 44th Annual Scientific Meeting of the International-Society-for-Experimental-Hematology (ISEH), Kyoto, Japan, 17-19 September 2015. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2015.06.157

Autologous Haematopotetic Stem Cell Transplantation Requires Recipient Bm Macrophages

2012

Conference Publication

The production of porcine anti-CSF-1R antibodies: reagents to evaluate the effects of CSF-1 on postnatal growth

Gow, D. J., Garceau, V., Moffat, L., Kapetanovic, R., Sester, D. and Hume, D. A. (2012). The production of porcine anti-CSF-1R antibodies: reagents to evaluate the effects of CSF-1 on postnatal growth. European Congress of Immunology, Glasgow Scotland, 5-8 September 2012. Chichester, West Sussex United Kingdom: Wiley-Blackwell.

The production of porcine anti-CSF-1R antibodies: reagents to evaluate the effects of CSF-1 on postnatal growth

2012

Conference Publication

Cross species reactivity of Interleukin 34 (IL-34)

Gow, D. J., Garceau, V., Sester, D. and Hume, D. A. (2012). Cross species reactivity of Interleukin 34 (IL-34). European Congress of Immunology, Glasgow, Scotland, 5-8 September 2012. Chichester, West Sussex United Kingdom: Wiley-Blackwell.

Cross species reactivity of Interleukin 34 (IL-34)

2011

Conference Publication

Gene targeting of the rat Csf1r locus using homologous recombination in ES cells

Upton, Kyle R., Pridans, Clare, Meek, Stephen, Sutherland, Linda, Whitelaw, Bruce, Burdon, Tom and Hume, David (2011). Gene targeting of the rat Csf1r locus using homologous recombination in ES cells. 10th Transgenic Technology Meeting (TT2011), Florida, United States, 24-26 October 2011. Dordrecht, Netherlands: Springer Netherlands. doi: 10.1007/s11248-011-9540-8

Gene targeting of the rat Csf1r locus using homologous recombination in ES cells

2010

Conference Publication

Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation

Forrest, A. R. R., Kanamori-Katayama, M., Tomaru, Y., Lassmann, T., Ninomiya, N., Takahashi, Y., de Hoon, M. J. L., Kubosaki, A., Kaiho, A., Suzuki, M., Yasuda, J., Kawai, J., Hayashizaki, Y., Hume, D. A. and Suzuki, H. (2010). Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation. ELSEVIER SCI LTD. doi: 10.1016/j.diff.2010.09.048

Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation

2009

Conference Publication

Osteomacs are critical for optimal intramembranous bone formation in a tibial defect model of bone healing

Alexander, K. A., Raggatt, L. J., Chang, M. K., Maylin, E. R., Muller, R., Kohler, T., Wu, A. C. K., Hume, D. A. and Pettit, A. R. (2009). Osteomacs are critical for optimal intramembranous bone formation in a tibial defect model of bone healing. 2nd Joint Meeting of the International Bone & Mineral Society and the Australian & New Zealand Bone & Mineral Society, Sydney, NSW, Australia, 21-25 March 2009. United States: Elsevier. doi: 10.1016/j.bone.2009.01.076

Osteomacs are critical for optimal intramembranous bone formation in a tibial defect model of bone healing

2009

Conference Publication

Osteomacs: osteoclast precursors during inflammatory bone disease but regulators of physiologic bone remodelling

Raggatt, L. J., Chang, M. K., Alexander, K. A., Maylin, E. R., Walsh, N. C., Gravallese, E. M., Hume, D. A. and Pettit, A. R. (2009). Osteomacs: osteoclast precursors during inflammatory bone disease but regulators of physiologic bone remodelling. 2nd Joint Meeting of the International Bone & Mineral Society and the Australian & New Zealand Bone & Mineral Society, Sydney, Australia, 21-25 March, 2009. New York: Elsevier Science. doi: 10.1016/j.bone.2009.01.300

Osteomacs: osteoclast precursors during inflammatory bone disease but regulators of physiologic bone remodelling

2009

Conference Publication

Docosahexaenoic acid (22:6n-3) protects from early retinal degeneration and attenuates microglial activation

Ebert, Stefanie, Weigelt, Karin, Drobnik, Wolfgang, Mauerer, Richard, Hume, David A., Weber, Bernhard H. F. and Langmann, Thomas (2009). Docosahexaenoic acid (22:6n-3) protects from early retinal degeneration and attenuates microglial activation. 50th International Conference on Bioscience of Lipids, Regenburg Germany, Sep 01-05, 2009. ELSEVIER IRELAND LTD. doi: 10.1016/j.chemphyslip.2009.06.022

Docosahexaenoic acid (22:6n-3) protects from early retinal degeneration and attenuates microglial activation