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2023

Journal Article

Erratum: Correction: Plasma extracellular vesicle phenotyping for the differentiation of early-stage lung cancer and benign lung diseases (Nanoscale horizons (2023) 8 6 (746-758))

Yuan, Liwen, Chen, Yanpin, Ke, Longfeng, Zhou, Quan, Chen, Jiayou, Fan, Min, Wuethrich, Alain, Trau, Matt and Wang, Jing (2023). Erratum: Correction: Plasma extracellular vesicle phenotyping for the differentiation of early-stage lung cancer and benign lung diseases (Nanoscale horizons (2023) 8 6 (746-758)). Nanoscale horizons, 8 (9) d3nh90028b, 1288-1289. doi: 10.1039/d3nh90028b

Erratum: Correction: Plasma extracellular vesicle phenotyping for the differentiation of early-stage lung cancer and benign lung diseases (Nanoscale horizons (2023) 8 6 (746-758))

2023

Journal Article

A microfluidic liquid biopsy platform to monitor protein biomarker heterogeneity in single circulating therapy‐resistance cancer cell

Ahmed, Emtiaz, Shanmugasundaram, Karthik Balaji, Li, Junrong, Behren, Andreas, Lobb, Richard, Möller, Andreas, Wuethrich, Alain, Dey, Shuvashis, Sina, Abu Ali Ibn and Trau, Matt (2023). A microfluidic liquid biopsy platform to monitor protein biomarker heterogeneity in single circulating therapy‐resistance cancer cell. Advanced Sensor Research, 2 (12) 2300059. doi: 10.1002/adsr.202300059

A microfluidic liquid biopsy platform to monitor protein biomarker heterogeneity in single circulating therapy‐resistance cancer cell

2023

Journal Article

A universal reagent for detection of emerging diseases using bioengineered multifunctional yeast nanofragments

Li, Junrong, Howard, Christopher B., Dey, Shuvashis, Lowry, Kym, Whiley, David M., Puttick, Simon, Rose, Stephen, Lobb, Richard J., Wuethrich, Alain, Edwardraja, Selvakumar and Trau, Matt (2023). A universal reagent for detection of emerging diseases using bioengineered multifunctional yeast nanofragments. Nature Nanotechnology, 18 (10), 1222-1229. doi: 10.1038/s41565-023-01415-1

A universal reagent for detection of emerging diseases using bioengineered multifunctional yeast nanofragments

2023

Journal Article

Plasma extracellular vesicle phenotyping for the differentiation of early-stage lung cancer and benign lung disease

Yuan, Liwen, Chen, Yanping, Ke, Longfeng, Zhou, Quan, Chen, Jiayou, Fan, Min, Wuethrich, Alain, Trau, Matt and Wang, Jing (2023). Plasma extracellular vesicle phenotyping for the differentiation of early-stage lung cancer and benign lung disease. Nanoscale Horizons, 8 (6), 746-758. doi: 10.1039/d2nh00570k

Plasma extracellular vesicle phenotyping for the differentiation of early-stage lung cancer and benign lung disease

2023

Journal Article

Liquid biopsy snapshots of key phosphoproteomic pathways in lung cancer patients for diagnosis and therapy monitoring

Ahmed, Mostak, Wuethrich, Alain, Constantin, Nicolas, Shanmugasundaram, Karthik Balaji, Mainwaring, Paul, Kulasinghe, Arutha, O’Leary, Connor, O’Byrne, Ken, Sina, Abu Ali Ibn, Carrascosa, Laura G. and Trau, Matt (2023). Liquid biopsy snapshots of key phosphoproteomic pathways in lung cancer patients for diagnosis and therapy monitoring. Analytical Chemistry, 95 (22), 8522-8532. doi: 10.1021/acs.analchem.3c00519

Liquid biopsy snapshots of key phosphoproteomic pathways in lung cancer patients for diagnosis and therapy monitoring

2023

Journal Article

A translational project of the WSG-ADAPT-TN trial demonstrates immunomodulatory and anti-viral defense gene networks predicting pathological complete response (pCR) and survival after de-escalated neoadjuvant chemotherapy (NACT) in early triple-negative breast cancer (eTNBC)

Graeser, M., Harbeck, N., Gluz, O., Nitz, U.A., Christgen, M., Kuemmel, S., Grischke, E-M., Forstbauer, H., Braun, M., Warm, M., Hackmann, J.C., Uleer, C., Aktas, B., Würstlein, R., Pelz, E., Eulenburg, C. Zu, Kreipe, H., Trau, M., Stirzaker, C. and Korbie, D. (2023). A translational project of the WSG-ADAPT-TN trial demonstrates immunomodulatory and anti-viral defense gene networks predicting pathological complete response (pCR) and survival after de-escalated neoadjuvant chemotherapy (NACT) in early triple-negative breast cancer (eTNBC). ESMO Open, 8 (1) 101242, 10-11. doi: 10.1016/j.esmoop.2023.101242

A translational project of the WSG-ADAPT-TN trial demonstrates immunomodulatory and anti-viral defense gene networks predicting pathological complete response (pCR) and survival after de-escalated neoadjuvant chemotherapy (NACT) in early triple-negative breast cancer (eTNBC)

2023

Journal Article

A multiplexed SERS microassay for accurate detection of SARS-CoV-2 and variants of concern

Vedelago, Courtney, Li, Junrong, Lowry, Kym, Howard, Christopher, Wuethrich, Alain and Trau, Matt (2023). A multiplexed SERS microassay for accurate detection of SARS-CoV-2 and variants of concern. ACS Sensors, 8 (4), 1648-1657. doi: 10.1021/acssensors.2c02782

A multiplexed SERS microassay for accurate detection of SARS-CoV-2 and variants of concern

2023

Journal Article

Digital decoding of single extracellular vesicle phenotype differentiates early malignant and benign lung lesions

Li, Junrong, Sina, Abu A. I., Antaw, Fiach, Fielding, David, Möller, Andreas, Lobb, Richard, Wuethrich, Alain and Trau, Matt (2023). Digital decoding of single extracellular vesicle phenotype differentiates early malignant and benign lung lesions. Advanced Science, 10 (1) 2204207, e2204207. doi: 10.1002/advs.202204207

Digital decoding of single extracellular vesicle phenotype differentiates early malignant and benign lung lesions

2023

Journal Article

Nanophotonic immunoarray with electrochemically roughened surfaces for handheld detection of secreted PD-L1 to predict immuno-oncology efficacy

Dey, Shuvashis, Koo, Kevin M., Ahmed, Emtiaz and Trau, Matt (2023). Nanophotonic immunoarray with electrochemically roughened surfaces for handheld detection of secreted PD-L1 to predict immuno-oncology efficacy. Lab on a Chip, 23 (15), 3443-3452. doi: 10.1039/d3lc00523b

Nanophotonic immunoarray with electrochemically roughened surfaces for handheld detection of secreted PD-L1 to predict immuno-oncology efficacy

2022

Journal Article

Tetraplex immunophenotyping of cell surface proteomes via synthesized plasmonic nanotags and portable raman spectroscopy

Wang, Jing, Koo, Kevin M. and Trau, Matt (2022). Tetraplex immunophenotyping of cell surface proteomes via synthesized plasmonic nanotags and portable raman spectroscopy. Analytical Chemistry, 94 (43), 14906-14916. doi: 10.1021/acs.analchem.2c02262

Tetraplex immunophenotyping of cell surface proteomes via synthesized plasmonic nanotags and portable raman spectroscopy

2022

Journal Article

SERS multiplex profiling of melanoma circulating tumor cells for predicting the response to immune checkpoint blockade therapy

Li, Junrong, Wuethrich, Alain, Zhang, Zhen, Wang, Jing, Lin, Lynlee L., Behren, Andreas, Wang, Yuling and Trau, Matt (2022). SERS multiplex profiling of melanoma circulating tumor cells for predicting the response to immune checkpoint blockade therapy. Analytical Chemistry, 94 (42), 14573-14582. doi: 10.1021/acs.analchem.2c02398

SERS multiplex profiling of melanoma circulating tumor cells for predicting the response to immune checkpoint blockade therapy

2022

Journal Article

Detection of Dengue Virus 2 with single infected mosquito resolution using yeast affinity bionanofragments and plasmonic SERS nanoboxes

Farokhinejad, Fahimeh, Li, Junrong, Hugo, Leon E., Howard, Christopher B., Wuethrich, Alain and Trau, Matt (2022). Detection of Dengue Virus 2 with single infected mosquito resolution using yeast affinity bionanofragments and plasmonic SERS nanoboxes. Analytical Chemistry, 94 (41), 14177-14184. doi: 10.1021/acs.analchem.2c02012

Detection of Dengue Virus 2 with single infected mosquito resolution using yeast affinity bionanofragments and plasmonic SERS nanoboxes

2022

Journal Article

Modelling clinical DNA fragmentation in the development of universal PCR-based assays for bisulfite-converted, formalin-fixed and cell-free DNA sample analysis

Johnston, Andrew D., Lu, Jennifer, Korbie, Darren and Trau, Matt (2022). Modelling clinical DNA fragmentation in the development of universal PCR-based assays for bisulfite-converted, formalin-fixed and cell-free DNA sample analysis. Scientific Reports, 12 (1) 16051, 1-18. doi: 10.1038/s41598-022-18196-7

Modelling clinical DNA fragmentation in the development of universal PCR-based assays for bisulfite-converted, formalin-fixed and cell-free DNA sample analysis

2022

Journal Article

An in vivo gene amplification system for high level expression in Saccharomyces cerevisiae

Peng, Bingyin, Esquirol, Lygie, Lu, Zeyu, Shen, Qianyi, Cheah, Li Chen, Howard, Christopher B., Scott, Colin, Trau, Matt, Dumsday, Geoff and Vickers, Claudia E. (2022). An in vivo gene amplification system for high level expression in Saccharomyces cerevisiae. Nature Communications, 13 (1) 2895, 2895. doi: 10.1038/s41467-022-30529-8

An in vivo gene amplification system for high level expression in Saccharomyces cerevisiae

2022

Journal Article

A T‐junction dual nanopore for single nanoparticle analysis

Liao, Caizhi, Antaw, Fiach, Wuethrich, Alain and Trau, Matt (2022). A T‐junction dual nanopore for single nanoparticle analysis. Advanced Engineering Materials, 24 (4) 2101015, 2101015. doi: 10.1002/adem.202101015

A T‐junction dual nanopore for single nanoparticle analysis

2022

Journal Article

C5b-9 membrane attack complex formation and extracellular vesicle shedding in Barrett’s esophagus and esophageal adenocarcinoma

Kolka, Cathryn M., Webster, Julie, Lepletier, Ailin, Winterford, Clay, Brown, Ian, Richards, Renee S., Zelek, Wioleta M., Cao, Yilang, Khamis, Ramlah, Shanmugasundaram, Karthik B., Wuethrich, Alain, Trau, Matt, Brosda, Sandra, Barbour, Andrew, Shah, Alok K., Eslick, Guy D., Clemons, Nicholas J., Morgan, B. Paul and Hill, Michelle M. (2022). C5b-9 membrane attack complex formation and extracellular vesicle shedding in Barrett’s esophagus and esophageal adenocarcinoma. Frontiers in Immunology, 13 842023. doi: 10.3389/fimmu.2022.842023

C5b-9 membrane attack complex formation and extracellular vesicle shedding in Barrett’s esophagus and esophageal adenocarcinoma

2022

Journal Article

Next-Generation Molecular Discovery: From Bottom-Up In Vivo and In Vitro Approaches to In Silico Top-Down Approaches for Therapeutics Neogenesis

Kenny, Sophie E., Antaw, Fiach, Locke, Warwick J., Howard, Christopher B., Korbie, Darren and Trau, Matt (2022). Next-Generation Molecular Discovery: From Bottom-Up In Vivo and In Vitro Approaches to In Silico Top-Down Approaches for Therapeutics Neogenesis. Life, 12 (3) 363, 1-24. doi: 10.3390/life12030363

Next-Generation Molecular Discovery: From Bottom-Up In Vivo and In Vitro Approaches to In Silico Top-Down Approaches for Therapeutics Neogenesis

2022

Journal Article

An electrochemical and raman scattering dual detection biosensor for rapid screening and biomolecular profiling of cancer biomarkers

Dey, Shuvashis, Ahmed, Emtiaz, Somvanshi, Pranjal Satishchandra, Sina, Abu Ali Ibn, Wuethrich, Alain and Trau, Matt (2022). An electrochemical and raman scattering dual detection biosensor for rapid screening and biomolecular profiling of cancer biomarkers. Chemosensors, 10 (3) 93, 93. doi: 10.3390/chemosensors10030093

An electrochemical and raman scattering dual detection biosensor for rapid screening and biomolecular profiling of cancer biomarkers

2022

Journal Article

Engineering eukaryote-like regulatory circuits to expand artificial control mechanisms for metabolic engineering in Saccharomyces cerevisiae

Peng, Bingyin, Bandari, Naga Chandra, Lu, Zeyu, Howard, Christopher B., Scott, Colin, Trau, Matt, Dumsday, Geoff and Vickers, Claudia E. (2022). Engineering eukaryote-like regulatory circuits to expand artificial control mechanisms for metabolic engineering in Saccharomyces cerevisiae. Communications Biology, 5 (1) 135, 135. doi: 10.1038/s42003-022-03070-z

Engineering eukaryote-like regulatory circuits to expand artificial control mechanisms for metabolic engineering in Saccharomyces cerevisiae

2022

Journal Article

Opportunities for early cancer detection: the rise of ctDNA methylation-based pan-cancer screening technologies

Constantin, Nicolas, Sina, Abu Ali Ibn, Korbie, Darren and Trau, Matt (2022). Opportunities for early cancer detection: the rise of ctDNA methylation-based pan-cancer screening technologies. Epigenomes, 6 (1) 6, 6. doi: 10.3390/epigenomes6010006

Opportunities for early cancer detection: the rise of ctDNA methylation-based pan-cancer screening technologies