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2026

Journal Article

Multifactor authentication in extracellular vesicle analysis: methods and approaches to address the heterogeneity problem

Zhou, Quan, Lobb, Richard J., Wuethrich, Alain and Trau, Matt (2026). Multifactor authentication in extracellular vesicle analysis: methods and approaches to address the heterogeneity problem. Nature Methods. doi: 10.1038/s41592-026-03068-z

Multifactor authentication in extracellular vesicle analysis: methods and approaches to address the heterogeneity problem

2026

Journal Article

Early-stage multi-cancer detection through a plasma extracellular vesicle protein signature

Lobb, Richard J., Zhou, Quan, Fielding, David, Visan, Kekoolani S., Wuethrich, Alain, Wang, Jing, Hu, Youran, Norris, Emma L., Hastie, Marcus L., Everitt, Sarah, Parris, Brielle, Aoude, Lauren G., Bonazzi, Vanessa F., Nixon, Elizabeth, Mooi, Jennifer, Koo, Kevin M., O'Byrne, Kenneth, Kulasinghe, Arutha, Bowman, Rayleen V., Yang, Ian A., Corcoran, Niall M., Hovens, Christopher M., MacManus, Michael, Gorman, Jeffrey J., Day, Bryan W., Hartel, Gunter, Whiteman, David C., Tebbutt, Niall, Mariadason, John M. ... Möller, Andreas (2026). Early-stage multi-cancer detection through a plasma extracellular vesicle protein signature. Cell Reports Medicine, 7 (4) 102694, 1-20. doi: 10.1016/j.xcrm.2026.102694

Early-stage multi-cancer detection through a plasma extracellular vesicle protein signature

2026

Journal Article

Glycaemic variability underlies myocyte dysfunction and myocardial injury risk in diabetes

Cao, Yuanzhao, Redd, Meredith A., Outhwaite, Jennifer E., Mizikovsky, Dalia, Shim, Woo Jun, Fang, Chen, Vedelago, Courtney, Tan, Clarissa, Wu, Zhixuan, Daygon, Dara, Stark, Terra, Palfreyman, Robin, Chiu, Han Sheng, Thomas, Ulrich, Dragicevic, Elena, Sng, Julian D. J., Saez, Natalie J., Barrett, Helen L., Dorey, Emily S., King, Glenn F., Wuethrich, Alain, Trau, Matt, Shah, Sonia, Short, Kirsty R. and Palpant, Nathan J. (2026). Glycaemic variability underlies myocyte dysfunction and myocardial injury risk in diabetes. Nature Communications. doi: 10.1038/s41467-026-71809-x

Glycaemic variability underlies myocyte dysfunction and myocardial injury risk in diabetes

2026

Journal Article

Nanobiosensors and Artificial Intelligence Strategies for Glycan Profiling in Cancer Progression: A Critical Review

Khamis, Ramlah, Wu, Yuao, Sina, Abu Ali Ibn, Trau, Matt and Wuethrich, Alain (2026). Nanobiosensors and Artificial Intelligence Strategies for Glycan Profiling in Cancer Progression: A Critical Review. ACS Sensors acssensors.5c04911. doi: 10.1021/acssensors.5c04911

Nanobiosensors and Artificial Intelligence Strategies for Glycan Profiling in Cancer Progression: A Critical Review

2026

Other Outputs

Multi-omics dataset of TGF-β-induced EMT in breast cancer

Zhang, Zhen, Ahmed, Emtiaz, Constantin, Nicholas, Lu, Jennifer, Portelli, Stephanie, Ascher, David, Korbie, Darren, Wuethrich, Alain, Sina, Abu and Trau, Matt (2026). Multi-omics dataset of TGF-β-induced EMT in breast cancer. The University of Queensland. (Dataset) doi: 10.48610/954d1e6

Multi-omics dataset of TGF-β-induced EMT in breast cancer

2026

Journal Article

Programmable dual‐targeting nano bioconjugates: a universal bioconjugation strategy to enhance single molecule proteomic assays

Farokhinejad, Fahimeh, Anderson, Will, Niu, Xueming, Wuethrich, Alain, Howard, Christopher B. and Trau, Matt (2026). Programmable dual‐targeting nano bioconjugates: a universal bioconjugation strategy to enhance single molecule proteomic assays. Small Methods, 10 (7) e01235, 1-13. doi: 10.1002/smtd.202501235

Programmable dual‐targeting nano bioconjugates: a universal bioconjugation strategy to enhance single molecule proteomic assays

2026

Journal Article

Study of the molecular level mechanism of nanoscale alternating current electrohydrodynamic flow

Alosious, Sobin, Antaw, Fiach, Trau, Matt, Tee, Shern R. and Searles, Debra J. (2026). Study of the molecular level mechanism of nanoscale alternating current electrohydrodynamic flow. International Communications in Heat and Mass Transfer, 173 110890, 1-11. doi: 10.1016/j.icheatmasstransfer.2026.110890

Study of the molecular level mechanism of nanoscale alternating current electrohydrodynamic flow

2026

Journal Article

A digital SERS platform powered by bispecific antibody fragments for SARS-CoV-2 diagnostics

Wang, Jing, Zhou, Quan, Lowry, Kym, Howard, Christopher B. and Trau, Matt (2026). A digital SERS platform powered by bispecific antibody fragments for SARS-CoV-2 diagnostics. Biosensors and Bioelectronics, 294 118252, 1-6. doi: 10.1016/j.bios.2025.118252

A digital SERS platform powered by bispecific antibody fragments for SARS-CoV-2 diagnostics

2026

Journal Article

Monitoring glioblastoma extracellular vesicle evolution using a nanodiagnostic platform to detect glioma stem cells driving recurrent disease

Zhang, Zhen, Lobb, Richard J., Tooney, Paul, Wang, Jing, Lane, Rebecca, Zhou, Quan, Niu, Xueming, Faulkner, Sam, Al-Iedani, Oun, Day, Bryan W., Puttick, Simon, Rose, Stephen, Fay, Mike and Trau, Matt (2026). Monitoring glioblastoma extracellular vesicle evolution using a nanodiagnostic platform to detect glioma stem cells driving recurrent disease. Science Advances, 12 (5) eadt2804, eadt2804. doi: 10.1126/sciadv.adt2804

Monitoring glioblastoma extracellular vesicle evolution using a nanodiagnostic platform to detect glioma stem cells driving recurrent disease

2026

Journal Article

Rapid Decentralized Prostate Cancer Risk Stratification by Portable Liquid Biopsy Analysis within a Clinical Biosensor Validation Framework

Koo, Kevin M., Phillips, Grant, Srihari, Sriganesh, Farrell, Áine, Jaradi, Binny, Fitzpatrick, Kira J., Yaxley, John W., Samaratunga, Hemamali, Mainwaring, Paul N., Ru, Ke‐lin, Korbie, Darren J., Tomlins, Scott A., Roberts, Matthew J., Gardiner, Robert A. and Trau, Matt (2026). Rapid Decentralized Prostate Cancer Risk Stratification by Portable Liquid Biopsy Analysis within a Clinical Biosensor Validation Framework. Advanced Science, 13 (13) e12126, e12126. doi: 10.1002/advs.202512126

Rapid Decentralized Prostate Cancer Risk Stratification by Portable Liquid Biopsy Analysis within a Clinical Biosensor Validation Framework

2026

Journal Article

A bacterial type-II toxin-antitoxin-mediated gene amplification system in Saccharomyces cerevisiae

Evans, Samuel, Lu, Zeyu, McDonnell, Liam, Anderson, Will, Peralta, Francisco, Watkins, Tyson, Ahmed, Hafna, Luna-Flores, Carlos Horacio, Loan, Thomas, Navone, Laura, Trau, Matt, Scott, Colin, Speight, Robert E., Vickers, Claudia E. and Peng, Bingyin (2026). A bacterial type-II toxin-antitoxin-mediated gene amplification system in Saccharomyces cerevisiae. Life Research, 9 (1) 2, 2. doi: 10.53388/lr20260002

A bacterial type-II toxin-antitoxin-mediated gene amplification system in Saccharomyces cerevisiae

2025

Journal Article

Ultrasensitive multiplex detection of lung cancer EV-associated immune checkpoints using a mesoporous gold enhanced SERS biosensor

Ahmed, Emtiaz, Masud, Mostafa Kamal, Wuethrich, Alain, Edwardraja, Selvakumar, Dey, Shuvashis, Hasan, Mahedi, Hossain, Md. Shahriar A., Yamauchi, Yusuke, Trau, Matt and Sina, Abu Ali Ibn (2025). Ultrasensitive multiplex detection of lung cancer EV-associated immune checkpoints using a mesoporous gold enhanced SERS biosensor. Nanoscale, 17 (48), 28143-28154. doi: 10.1039/d5nr03653d

Ultrasensitive multiplex detection of lung cancer EV-associated immune checkpoints using a mesoporous gold enhanced SERS biosensor

2025

Journal Article

A digital single‐molecule nanocavity assay to monitor phosphoprotein circuits in single‐cell

Miao, Xinzhe, Shanmugasundaram, Karthik, Vedelago, Courtney, Naei, Vahid Yaghoubi, Kulasinghe, Arutha, Lobb, Richard, Trau, Matt and Wuethrich, Alain (2025). A digital single‐molecule nanocavity assay to monitor phosphoprotein circuits in single‐cell. Advanced Materials Technologies, 11 (7) e02611. doi: 10.1002/admt.202502611

A digital single‐molecule nanocavity assay to monitor phosphoprotein circuits in single‐cell

2025

Journal Article

Immunomodulatory gene networks predict treatment response and survival to de-escalated, anthracycline-free neoadjuvant chemotherapy in triple-negative breast cancer in the WSG-ADAPT-TN trial

Korbie, Darren, Stirzaker, Clare, Gluz, Oleg, zu Eulenburg, Christine, Nitz, Ulrike, Christgen, Matthias, Kuemmel, Sherko, Grischke, Eva-Maria, Forstbauer, Helmut, Braun, Michael, Warm, Mathias, Hackmann, John, Uleer, Christoph, Aktas, Bahriye, Schumacher, Claudia, Wuerstlein, Rachel, Pelz, Enrico, Kreipe, Hans Heinrich, Clark, Susan J., Trau, Matt, Graeser, Monika and Harbeck, Nadia (2025). Immunomodulatory gene networks predict treatment response and survival to de-escalated, anthracycline-free neoadjuvant chemotherapy in triple-negative breast cancer in the WSG-ADAPT-TN trial. Molecular Cancer, 24 (1) 96, 1-8. doi: 10.1186/s12943-025-02275-0

Immunomodulatory gene networks predict treatment response and survival to de-escalated, anthracycline-free neoadjuvant chemotherapy in triple-negative breast cancer in the WSG-ADAPT-TN trial

2025

Journal Article

Post-synthetic functionalization of covalent organic frameworks for highly sensitive and selective detection of plasticizers

Lo, Rabindranath, Ippili, Swathi, Sharma, Saandra, Ajith, Abhirami, Trau, Matt, Kment, Stepan, Narayana, Chandrabhas, Siddhanta, Soumik and Jayaramulu, Kolleboyina (2025). Post-synthetic functionalization of covalent organic frameworks for highly sensitive and selective detection of plasticizers. Chemistry-An Asian Journal, 20 (20) e00789, 1-9. doi: 10.1002/asia.202500789

Post-synthetic functionalization of covalent organic frameworks for highly sensitive and selective detection of plasticizers

2025

Journal Article

Physicochemical tuning of bispecific antibody fragment immobilization for robust digital SERS biosensing

Wang, Jing, Zhou, Quan, Howard, Christopher B. and Trau, Matt (2025). Physicochemical tuning of bispecific antibody fragment immobilization for robust digital SERS biosensing. Analytical Chemistry, 97 (43), 23994-24002. doi: 10.1021/acs.analchem.5c03980

Physicochemical tuning of bispecific antibody fragment immobilization for robust digital SERS biosensing

2025

Journal Article

The SeqSplice multiplexed minigene splicing assay for characterization and quantitation of variant-induced BRCA1 and BRCA2 splice isoforms

Canson, Daffodil M., Parsons, Michael T., Moir-Meyer, Gemma, Dumenil, Troy, Montalban, Gemma, Lin, Erica, McVeigh, Terri P., Davidson, Aimee L., Bouckaert, Shaun M., Trau, Matt, Korbie, Darren and Spurdle, Amanda B. (2025). The SeqSplice multiplexed minigene splicing assay for characterization and quantitation of variant-induced BRCA1 and BRCA2 splice isoforms. Genome Research, 35 (9), 2104-2115. doi: 10.1101/gr.279557.124

The SeqSplice multiplexed minigene splicing assay for characterization and quantitation of variant-induced BRCA1 and BRCA2 splice isoforms

2025

Journal Article

Single extracellular vesicle profiling to define brain specific traumatic brain injury induced neuro‐inflammation

Zhang, Zhen, Lobb, Richard J., Lane, Rebecca E., To, Xuan Vinh, Niu, Xueming, Antaw, Fiach, Pietrogrande, Giovanni, Winter, Craig, Wuethrich, Alain, Nasrallah, Fatima and Trau, Matt (2025). Single extracellular vesicle profiling to define brain specific traumatic brain injury induced neuro‐inflammation. Small Methods, 9 (7) 2401931, 1-9. doi: 10.1002/smtd.202401931

Single extracellular vesicle profiling to define brain specific traumatic brain injury induced neuro‐inflammation

2025

Journal Article

Multiplex cardiac biomarker profiling for precision coronary artery disease risk assessment using SERS with cubic core–satellite nanostructures

Zhang, Tuotuo, Li, Bin, Wuethrich, Alain, Liu, Huixing, Zhou, Quan, Hu, Zhuoran, Wang, Huiling, Trau, Matt, Bao, Feng, Li, Jian, Sun, Yao and Li, Junrong (2025). Multiplex cardiac biomarker profiling for precision coronary artery disease risk assessment using SERS with cubic core–satellite nanostructures. Analytical Chemistry, 97 (27), 14750-14760. doi: 10.1021/acs.analchem.5c02349

Multiplex cardiac biomarker profiling for precision coronary artery disease risk assessment using SERS with cubic core–satellite nanostructures

2025

Journal Article

High-throughput enrichment of functional disulfide-rich peptides by droplet microfluidics

Xie, Jing, Yap, Kuok, de Veer, Simon J., Edwardraja, Selvakumar, Durek, Thomas, Trau, Matt, Craik, David J. and Wang, Conan K. (2025). High-throughput enrichment of functional disulfide-rich peptides by droplet microfluidics. Lab on a Chip, 25 (14), 3525-3536. doi: 10.1039/d5lc00261c

High-throughput enrichment of functional disulfide-rich peptides by droplet microfluidics