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2022

Journal Article

Engineering eukaryote-like regulatory circuits to expand artificial control mechanisms for metabolic engineering in Saccharomyces cerevisiae

Peng, Bingyin, Bandari, Naga Chandra, Lu, Zeyu, Howard, Christopher B., Scott, Colin, Trau, Matt, Dumsday, Geoff and Vickers, Claudia E. (2022). Engineering eukaryote-like regulatory circuits to expand artificial control mechanisms for metabolic engineering in Saccharomyces cerevisiae. Communications Biology, 5 (1) 135, 135. doi: 10.1038/s42003-022-03070-z

Engineering eukaryote-like regulatory circuits to expand artificial control mechanisms for metabolic engineering in Saccharomyces cerevisiae

2022

Journal Article

Opportunities for early cancer detection: the rise of ctDNA methylation-based pan-cancer screening technologies

Constantin, Nicolas, Sina, Abu Ali Ibn, Korbie, Darren and Trau, Matt (2022). Opportunities for early cancer detection: the rise of ctDNA methylation-based pan-cancer screening technologies. Epigenomes, 6 (1) 6, 6. doi: 10.3390/epigenomes6010006

Opportunities for early cancer detection: the rise of ctDNA methylation-based pan-cancer screening technologies

2022

Journal Article

Toward precision oncology: SERS microfluidic systems for multiplex biomarker analysis in liquid biopsy

Shanmugasundaram, Karthik Balaji, Li, Junrong, Sina, Abu Ibn, Wuethrich, Alain and Trau, Matt (2022). Toward precision oncology: SERS microfluidic systems for multiplex biomarker analysis in liquid biopsy. Materials Advances, 3 (3), 1459-1471. doi: 10.1039/d1ma00848j

Toward precision oncology: SERS microfluidic systems for multiplex biomarker analysis in liquid biopsy

2022

Book Chapter

Multiplex PCR design for scalable resequencing

Korbie, Darren and Trau, Matt (2022). Multiplex PCR design for scalable resequencing. PCR Primer Design. (pp. 143-158) edited by Chhandak Basu. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-1799-1_11

Multiplex PCR design for scalable resequencing

2022

Journal Article

Molecular locker probe enrichment of gene fusion variants from matched patient liquid biopsy specimens for magneto-bioelectrocatalytic nanosensing

Koo, Kevin M. and Trau, Matt (2022). Molecular locker probe enrichment of gene fusion variants from matched patient liquid biopsy specimens for magneto-bioelectrocatalytic nanosensing. Nanoscale, 14 (11), 4225-4233. doi: 10.1039/d1nr07845c

Molecular locker probe enrichment of gene fusion variants from matched patient liquid biopsy specimens for magneto-bioelectrocatalytic nanosensing

2021

Journal Article

Dynamic monitoring of EMT in CTCs as an indicator of cancer metastasis

Zhang, Zhen, Wuethrich, Alain, Wang, Jing, Korbie, Darren, Lin, Lynlee L. and Trau, Matt (2021). Dynamic monitoring of EMT in CTCs as an indicator of cancer metastasis. Analytical Chemistry, 93 (50) acs.analchem.1c03167, 16787-16795. doi: 10.1021/acs.analchem.1c03167

Dynamic monitoring of EMT in CTCs as an indicator of cancer metastasis

2021

Journal Article

Progressing antimicrobial resistance sensing technologies across human, animal, and environmental health domains

Fitzpatrick, Kira J., Rohlf, Hayden J., Sutherland, Tara D., Koo, Kevin M., Beckett, Sam, Okelo, Walter O., Keyburn, Anthony L., Morgan, Branwen S., Drigo, Barbara, Trau, Matt, Donner, Erica, Djordjevic, Steven P. and De Barro, Paul J. (2021). Progressing antimicrobial resistance sensing technologies across human, animal, and environmental health domains. ACS Sensors, 6 (12) acssensors.1c01973, 4283-4296. doi: 10.1021/acssensors.1c01973

Progressing antimicrobial resistance sensing technologies across human, animal, and environmental health domains

2021

Journal Article

Generation of nanoyeast single-chain variable fragments as high-avidity biomaterials for dengue virus detection

Farokhinejad, Fahimeh, Lane, Rebecca E., Lobb, Richard J., Edwardraja, Selvakumar, Wuethrich, Alain, Howard, Christopher B. and Trau, Matt (2021). Generation of nanoyeast single-chain variable fragments as high-avidity biomaterials for dengue virus detection. ACS Biomaterials Science and Engineering, 7 (12) acsbiomaterials.1c01001, 5850-5860. doi: 10.1021/acsbiomaterials.1c01001

Generation of nanoyeast single-chain variable fragments as high-avidity biomaterials for dengue virus detection

2021

Journal Article

An integrated microfluidic‐SERS platform enables sensitive phenotyping of serum extracellular vesicles in early stage melanomas

Wang, Jing, Kao, Yung‐Ching, Zhou, Quan, Wuethrich, Alain, Stark, Mitchell S., Schaider, Helmut, Soyer, H. Peter, Lin, Lynlee L. and Trau, Matt (2021). An integrated microfluidic‐SERS platform enables sensitive phenotyping of serum extracellular vesicles in early stage melanomas. Advanced Functional Materials, 32 (3) 2010296, 1-9. doi: 10.1002/adfm.202010296

An integrated microfluidic‐SERS platform enables sensitive phenotyping of serum extracellular vesicles in early stage melanomas

2021

Journal Article

Characterizing the heterogeneity of small extracellular vesicle populations in multiple cancer types via an ultrasensitive chip

Wang, Jing, Wuethrich, Alain, Lobb, Richard J., Antaw, Fiach, Sina, Abu Ali Ibn, Lane, Rebecca E., Zhou, Quan, Zieschank, Chloe, Bell, Caroline, Bonazzi, Vanessa F., Aoude, Lauren G., Everitt, Sarah, Yeo, Belinda, Barbour, Andrew P., Möller, Andreas and Trau, Matt (2021). Characterizing the heterogeneity of small extracellular vesicle populations in multiple cancer types via an ultrasensitive chip. ACS Sensors, 6 (9) acssensors.1c00358, 3182-3194. doi: 10.1021/acssensors.1c00358

Characterizing the heterogeneity of small extracellular vesicle populations in multiple cancer types via an ultrasensitive chip

2021

Journal Article

Amplification-free SARS-CoV-2 detection using nanoyeast-scFv and ultrasensitive plasmonic nanobox-integrated nanomixing microassay

Li, Junrong, Wuethrich, Alain, Edwardraja, Selvakumar, Lobb, Richard J., Puttick, Simon, Rose, Stephen, Howard, Christopher B. and Trau, Matt (2021). Amplification-free SARS-CoV-2 detection using nanoyeast-scFv and ultrasensitive plasmonic nanobox-integrated nanomixing microassay. Analytical Chemistry, 93 (29) acs.analchem.1c01657, 10251-10260. doi: 10.1021/acs.analchem.1c01657

Amplification-free SARS-CoV-2 detection using nanoyeast-scFv and ultrasensitive plasmonic nanobox-integrated nanomixing microassay

2021

Journal Article

In situ single cell proteomics reveals circulating tumor cell heterogeneity during treatment

Reza, K. Kamil, Dey, Shuvashis, Wuethrich, Alain, Wang, Jing, Behren, Andreas, Antaw, Fiach, Wang, Yuling, Sina, Abu Ali Ibn and Trau, Matt (2021). In situ single cell proteomics reveals circulating tumor cell heterogeneity during treatment. ACS Nano, 15 (7) acsnano.0c10008, 11231-11243. doi: 10.1021/acsnano.0c10008

In situ single cell proteomics reveals circulating tumor cell heterogeneity during treatment

2021

Journal Article

Development of EndoScreen chip, a microfluidic pre-endoscopy triage test for esophageal adenocarcinoma

Webster, Julie A., Wuethrich, Alain, Shanmugasundaram, Karthik B., Richards, Renee S., Zelek, Wioleta M., Shah, Alok K., Gordon, Louisa G., Kendall, Bradley J., Hartel, Gunter, Morgan, B. Paul, Trau, Matt and Hill, Michelle M. (2021). Development of EndoScreen chip, a microfluidic pre-endoscopy triage test for esophageal adenocarcinoma. Cancers, 13 (12) 2865, 2865. doi: 10.3390/cancers13122865

Development of EndoScreen chip, a microfluidic pre-endoscopy triage test for esophageal adenocarcinoma

2021

Journal Article

On the behavior of nanoparticles beyond the nanopore interface

Antaw, Fiach, Anderson, Will, Wuethrich, Alain and Trau, Matt (2021). On the behavior of nanoparticles beyond the nanopore interface. Langmuir, 37 (16), 4772-4782. doi: 10.1021/acs.langmuir.0c03083

On the behavior of nanoparticles beyond the nanopore interface

2021

Book Chapter

Simultaneous BRAFV600E protein and DNA aberration detection in circulating melanoma cells using an integrated multimolecular sensor

Wuethrich, Alain, Dey, Shuvashis, Koo, Kevin M, Sina, Abu A. I. and Trau, Matt (2021). Simultaneous BRAFV600E protein and DNA aberration detection in circulating melanoma cells using an integrated multimolecular sensor. Melanoma. (pp. 265-276) New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-1205-7_20

Simultaneous BRAFV600E protein and DNA aberration detection in circulating melanoma cells using an integrated multimolecular sensor

2021

Journal Article

A digital single-molecule nanopillar SERS platform for predicting and monitoring immune toxicities in immunotherapy

Li, Junrong, Wuethrich, Alain, Sina, Abu A. I., Cheng, Han-Hao, Wang, Yuling, Behren, Andreas, Mainwaring, Paul N. and Trau, Matt (2021). A digital single-molecule nanopillar SERS platform for predicting and monitoring immune toxicities in immunotherapy. Nature Communications, 12 (1) 1087, 1-12. doi: 10.1038/s41467-021-21431-w

A digital single-molecule nanopillar SERS platform for predicting and monitoring immune toxicities in immunotherapy

2021

Journal Article

Network mapping of primary CD34+ cells by Ampliseq based whole transcriptome targeted resequencing identifies unexplored differentiation regulatory relationships

Schwaber, Jessica L., Korbie, Darren, Andersen, Stacey, Lin, Erica, Chrysanthopoulos, Panagiotis K., Trau, Matt and Nielsen, Lars K. (2021). Network mapping of primary CD34+ cells by Ampliseq based whole transcriptome targeted resequencing identifies unexplored differentiation regulatory relationships. PLoS ONE, 16 (2 ) e0246107, e0246107. doi: 10.1371/journal.pone.0246107

Network mapping of primary CD34+ cells by Ampliseq based whole transcriptome targeted resequencing identifies unexplored differentiation regulatory relationships

2021

Journal Article

Nucleic acid hybridization-based noise suppression for ultraselective multiplexed amplification of mutant variants

Zeng, Yi, Koo, Kevin M., Shen, Ai-Guo, Hu, Ji-Ming and Trau, Matt (2021). Nucleic acid hybridization-based noise suppression for ultraselective multiplexed amplification of mutant variants. Small, 17 (2) 2006370, e2006370. doi: 10.1002/smll.202006370

Nucleic acid hybridization-based noise suppression for ultraselective multiplexed amplification of mutant variants

2020

Journal Article

Nanostructured mesoporous gold biosensor for microRNA detection at attomolar level

Masud, Mostafa Kamal, Na, Jongbeom, Lin, Tzu-En, Malgras, Victor, Preet, Anant, Ibn Sina, Abu Ali, Wood, Kathleen, Billah, Mutasim, Kim, Jeonghun, You, Jungmok, Kani, Kenya, Whitten, Andrew E., Salomon, Carlos, Nguyen, Nam-Trung, Shiddiky, Muhammad J.A., Trau, Matt, Hossain, MdShahriar A. and Yamauchi, Yusuke (2020). Nanostructured mesoporous gold biosensor for microRNA detection at attomolar level. Biosensors and Bioelectronics, 168 112429, 1-9. doi: 10.1016/j.bios.2020.112429

Nanostructured mesoporous gold biosensor for microRNA detection at attomolar level

2020

Journal Article

Regulation of canonical oncogenic signaling pathways in cancer via DNA methylation

Lu, Jennifer, Wilfred, Premila, Korbie, Darren and Trau, Matt (2020). Regulation of canonical oncogenic signaling pathways in cancer via DNA methylation. Cancers, 12 (11) 3199, 1-29. doi: 10.3390/cancers12113199

Regulation of canonical oncogenic signaling pathways in cancer via DNA methylation