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2023

Journal Article

Digital decoding of single extracellular vesicle phenotype differentiates early malignant and benign lung lesions

Li, Junrong, Sina, Abu A. I., Antaw, Fiach, Fielding, David, Möller, Andreas, Lobb, Richard, Wuethrich, Alain and Trau, Matt (2023). Digital decoding of single extracellular vesicle phenotype differentiates early malignant and benign lung lesions. Advanced Science, 10 (1) 2204207, e2204207. doi: 10.1002/advs.202204207

Digital decoding of single extracellular vesicle phenotype differentiates early malignant and benign lung lesions

2023

Journal Article

Nanophotonic immunoarray with electrochemically roughened surfaces for handheld detection of secreted PD-L1 to predict immuno-oncology efficacy

Dey, Shuvashis, Koo, Kevin M., Ahmed, Emtiaz and Trau, Matt (2023). Nanophotonic immunoarray with electrochemically roughened surfaces for handheld detection of secreted PD-L1 to predict immuno-oncology efficacy. Lab on a Chip, 23 (15), 3443-3452. doi: 10.1039/d3lc00523b

Nanophotonic immunoarray with electrochemically roughened surfaces for handheld detection of secreted PD-L1 to predict immuno-oncology efficacy

2022

Journal Article

Tetraplex immunophenotyping of cell surface proteomes via synthesized plasmonic nanotags and portable raman spectroscopy

Wang, Jing, Koo, Kevin M. and Trau, Matt (2022). Tetraplex immunophenotyping of cell surface proteomes via synthesized plasmonic nanotags and portable raman spectroscopy. Analytical Chemistry, 94 (43), 14906-14916. doi: 10.1021/acs.analchem.2c02262

Tetraplex immunophenotyping of cell surface proteomes via synthesized plasmonic nanotags and portable raman spectroscopy

2022

Journal Article

SERS multiplex profiling of melanoma circulating tumor cells for predicting the response to immune checkpoint blockade therapy

Li, Junrong, Wuethrich, Alain, Zhang, Zhen, Wang, Jing, Lin, Lynlee L., Behren, Andreas, Wang, Yuling and Trau, Matt (2022). SERS multiplex profiling of melanoma circulating tumor cells for predicting the response to immune checkpoint blockade therapy. Analytical Chemistry, 94 (42), 14573-14582. doi: 10.1021/acs.analchem.2c02398

SERS multiplex profiling of melanoma circulating tumor cells for predicting the response to immune checkpoint blockade therapy

2022

Journal Article

Detection of Dengue Virus 2 with single infected mosquito resolution using yeast affinity bionanofragments and plasmonic SERS nanoboxes

Farokhinejad, Fahimeh, Li, Junrong, Hugo, Leon E., Howard, Christopher B., Wuethrich, Alain and Trau, Matt (2022). Detection of Dengue Virus 2 with single infected mosquito resolution using yeast affinity bionanofragments and plasmonic SERS nanoboxes. Analytical Chemistry, 94 (41), 14177-14184. doi: 10.1021/acs.analchem.2c02012

Detection of Dengue Virus 2 with single infected mosquito resolution using yeast affinity bionanofragments and plasmonic SERS nanoboxes

2022

Journal Article

Modelling clinical DNA fragmentation in the development of universal PCR-based assays for bisulfite-converted, formalin-fixed and cell-free DNA sample analysis

Johnston, Andrew D., Lu, Jennifer, Korbie, Darren and Trau, Matt (2022). Modelling clinical DNA fragmentation in the development of universal PCR-based assays for bisulfite-converted, formalin-fixed and cell-free DNA sample analysis. Scientific Reports, 12 (1) 16051, 1-18. doi: 10.1038/s41598-022-18196-7

Modelling clinical DNA fragmentation in the development of universal PCR-based assays for bisulfite-converted, formalin-fixed and cell-free DNA sample analysis

2022

Journal Article

An in vivo gene amplification system for high level expression in Saccharomyces cerevisiae

Peng, Bingyin, Esquirol, Lygie, Lu, Zeyu, Shen, Qianyi, Cheah, Li Chen, Howard, Christopher B., Scott, Colin, Trau, Matt, Dumsday, Geoff and Vickers, Claudia E. (2022). An in vivo gene amplification system for high level expression in Saccharomyces cerevisiae. Nature Communications, 13 (1) 2895, 2895. doi: 10.1038/s41467-022-30529-8

An in vivo gene amplification system for high level expression in Saccharomyces cerevisiae

2022

Journal Article

A T‐junction dual nanopore for single nanoparticle analysis

Liao, Caizhi, Antaw, Fiach, Wuethrich, Alain and Trau, Matt (2022). A T‐junction dual nanopore for single nanoparticle analysis. Advanced Engineering Materials, 24 (4) 2101015, 2101015. doi: 10.1002/adem.202101015

A T‐junction dual nanopore for single nanoparticle analysis

2022

Journal Article

C5b-9 membrane attack complex formation and extracellular vesicle shedding in Barrett’s esophagus and esophageal adenocarcinoma

Kolka, Cathryn M., Webster, Julie, Lepletier, Ailin, Winterford, Clay, Brown, Ian, Richards, Renee S., Zelek, Wioleta M., Cao, Yilang, Khamis, Ramlah, Shanmugasundaram, Karthik B., Wuethrich, Alain, Trau, Matt, Brosda, Sandra, Barbour, Andrew, Shah, Alok K., Eslick, Guy D., Clemons, Nicholas J., Morgan, B. Paul and Hill, Michelle M. (2022). C5b-9 membrane attack complex formation and extracellular vesicle shedding in Barrett’s esophagus and esophageal adenocarcinoma. Frontiers in Immunology, 13 842023. doi: 10.3389/fimmu.2022.842023

C5b-9 membrane attack complex formation and extracellular vesicle shedding in Barrett’s esophagus and esophageal adenocarcinoma

2022

Journal Article

Next-Generation Molecular Discovery: From Bottom-Up In Vivo and In Vitro Approaches to In Silico Top-Down Approaches for Therapeutics Neogenesis

Kenny, Sophie E., Antaw, Fiach, Locke, Warwick J., Howard, Christopher B., Korbie, Darren and Trau, Matt (2022). Next-Generation Molecular Discovery: From Bottom-Up In Vivo and In Vitro Approaches to In Silico Top-Down Approaches for Therapeutics Neogenesis. Life, 12 (3) 363, 1-24. doi: 10.3390/life12030363

Next-Generation Molecular Discovery: From Bottom-Up In Vivo and In Vitro Approaches to In Silico Top-Down Approaches for Therapeutics Neogenesis

2022

Journal Article

An electrochemical and raman scattering dual detection biosensor for rapid screening and biomolecular profiling of cancer biomarkers

Dey, Shuvashis, Ahmed, Emtiaz, Somvanshi, Pranjal Satishchandra, Sina, Abu Ali Ibn, Wuethrich, Alain and Trau, Matt (2022). An electrochemical and raman scattering dual detection biosensor for rapid screening and biomolecular profiling of cancer biomarkers. Chemosensors, 10 (3) 93, 93. doi: 10.3390/chemosensors10030093

An electrochemical and raman scattering dual detection biosensor for rapid screening and biomolecular profiling of cancer biomarkers

2022

Journal Article

Engineering eukaryote-like regulatory circuits to expand artificial control mechanisms for metabolic engineering in Saccharomyces cerevisiae

Peng, Bingyin, Bandari, Naga Chandra, Lu, Zeyu, Howard, Christopher B., Scott, Colin, Trau, Matt, Dumsday, Geoff and Vickers, Claudia E. (2022). Engineering eukaryote-like regulatory circuits to expand artificial control mechanisms for metabolic engineering in Saccharomyces cerevisiae. Communications Biology, 5 (1) 135, 135. doi: 10.1038/s42003-022-03070-z

Engineering eukaryote-like regulatory circuits to expand artificial control mechanisms for metabolic engineering in Saccharomyces cerevisiae

2022

Journal Article

Opportunities for early cancer detection: the rise of ctDNA methylation-based pan-cancer screening technologies

Constantin, Nicolas, Sina, Abu Ali Ibn, Korbie, Darren and Trau, Matt (2022). Opportunities for early cancer detection: the rise of ctDNA methylation-based pan-cancer screening technologies. Epigenomes, 6 (1) 6, 6. doi: 10.3390/epigenomes6010006

Opportunities for early cancer detection: the rise of ctDNA methylation-based pan-cancer screening technologies

2022

Journal Article

Toward precision oncology: SERS microfluidic systems for multiplex biomarker analysis in liquid biopsy

Shanmugasundaram, Karthik Balaji, Li, Junrong, Sina, Abu Ibn, Wuethrich, Alain and Trau, Matt (2022). Toward precision oncology: SERS microfluidic systems for multiplex biomarker analysis in liquid biopsy. Materials Advances, 3 (3), 1459-1471. doi: 10.1039/d1ma00848j

Toward precision oncology: SERS microfluidic systems for multiplex biomarker analysis in liquid biopsy

2022

Book Chapter

Multiplex PCR design for scalable resequencing

Korbie, Darren and Trau, Matt (2022). Multiplex PCR design for scalable resequencing. PCR Primer Design. (pp. 143-158) edited by Chhandak Basu. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-1799-1_11

Multiplex PCR design for scalable resequencing

2022

Journal Article

Molecular locker probe enrichment of gene fusion variants from matched patient liquid biopsy specimens for magneto-bioelectrocatalytic nanosensing

Koo, Kevin M. and Trau, Matt (2022). Molecular locker probe enrichment of gene fusion variants from matched patient liquid biopsy specimens for magneto-bioelectrocatalytic nanosensing. Nanoscale, 14 (11), 4225-4233. doi: 10.1039/d1nr07845c

Molecular locker probe enrichment of gene fusion variants from matched patient liquid biopsy specimens for magneto-bioelectrocatalytic nanosensing

2021

Journal Article

Dynamic monitoring of EMT in CTCs as an indicator of cancer metastasis

Zhang, Zhen, Wuethrich, Alain, Wang, Jing, Korbie, Darren, Lin, Lynlee L. and Trau, Matt (2021). Dynamic monitoring of EMT in CTCs as an indicator of cancer metastasis. Analytical Chemistry, 93 (50) acs.analchem.1c03167, 16787-16795. doi: 10.1021/acs.analchem.1c03167

Dynamic monitoring of EMT in CTCs as an indicator of cancer metastasis

2021

Journal Article

Progressing antimicrobial resistance sensing technologies across human, animal, and environmental health domains

Fitzpatrick, Kira J., Rohlf, Hayden J., Sutherland, Tara D., Koo, Kevin M., Beckett, Sam, Okelo, Walter O., Keyburn, Anthony L., Morgan, Branwen S., Drigo, Barbara, Trau, Matt, Donner, Erica, Djordjevic, Steven P. and De Barro, Paul J. (2021). Progressing antimicrobial resistance sensing technologies across human, animal, and environmental health domains. ACS Sensors, 6 (12) acssensors.1c01973, 4283-4296. doi: 10.1021/acssensors.1c01973

Progressing antimicrobial resistance sensing technologies across human, animal, and environmental health domains

2021

Journal Article

Generation of nanoyeast single-chain variable fragments as high-avidity biomaterials for dengue virus detection

Farokhinejad, Fahimeh, Lane, Rebecca E., Lobb, Richard J., Edwardraja, Selvakumar, Wuethrich, Alain, Howard, Christopher B. and Trau, Matt (2021). Generation of nanoyeast single-chain variable fragments as high-avidity biomaterials for dengue virus detection. ACS Biomaterials Science and Engineering, 7 (12) acsbiomaterials.1c01001, 5850-5860. doi: 10.1021/acsbiomaterials.1c01001

Generation of nanoyeast single-chain variable fragments as high-avidity biomaterials for dengue virus detection

2021

Journal Article

An integrated microfluidic‐SERS platform enables sensitive phenotyping of serum extracellular vesicles in early stage melanomas

Wang, Jing, Kao, Yung‐Ching, Zhou, Quan, Wuethrich, Alain, Stark, Mitchell S., Schaider, Helmut, Soyer, H. Peter, Lin, Lynlee L. and Trau, Matt (2021). An integrated microfluidic‐SERS platform enables sensitive phenotyping of serum extracellular vesicles in early stage melanomas. Advanced Functional Materials, 32 (3) 2010296, 1-9. doi: 10.1002/adfm.202010296

An integrated microfluidic‐SERS platform enables sensitive phenotyping of serum extracellular vesicles in early stage melanomas