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2025 Journal Article Immunomodulatory gene networks predict treatment response and survival to de-escalated, anthracycline-free neoadjuvant chemotherapy in triple-negative breast cancer in the WSG-ADAPT-TN trialKorbie, Darren, Stirzaker, Clare, Gluz, Oleg, zu Eulenburg, Christine, Nitz, Ulrike, Christgen, Matthias, Kuemmel, Sherko, Grischke, Eva-Maria, Forstbauer, Helmut, Braun, Michael, Warm, Mathias, Hackmann, John, Uleer, Christoph, Aktas, Bahriye, Schumacher, Claudia, Wuerstlein, Rachel, Pelz, Enrico, Kreipe, Hans Heinrich, Clark, Susan J., Trau, Matt, Graeser, Monika and Harbeck, Nadia (2025). Immunomodulatory gene networks predict treatment response and survival to de-escalated, anthracycline-free neoadjuvant chemotherapy in triple-negative breast cancer in the WSG-ADAPT-TN trial. Molecular Cancer, 24 (1) 96, 1-8. doi: 10.1186/s12943-025-02275-0 |
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2025 Journal Article Multiplex Cardiac Biomarker Profiling for Precision Coronary Artery Disease Risk Assessment Using SERS with Cubic Core–Satellite NanostructuresZhang, Tuotuo, Li, Bin, Wuethrich, Alain, Liu, Huixing, Zhou, Quan, Hu, Zhuoran, Wang, Huiling, Trau, Matt, Bao, Feng, Li, Jian, Sun, Yao and Li, Junrong (2025). Multiplex Cardiac Biomarker Profiling for Precision Coronary Artery Disease Risk Assessment Using SERS with Cubic Core–Satellite Nanostructures. Analytical Chemistry. doi: 10.1021/acs.analchem.5c02349 |
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2025 Journal Article Conventional techniques and emerging nanotechnologies for early detection of cancer metastasis via epithelial-mesenchymal transition monitoringZhang, Zhen, Wang, Jing, Wuethrich, Alain and Trau, Matt (2025). Conventional techniques and emerging nanotechnologies for early detection of cancer metastasis via epithelial-mesenchymal transition monitoring. National Science Review, 12 (3) nwae452, 1-17. doi: 10.1093/nsr/nwae452 |
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2025 Journal Article Surface-Enhanced Raman Spectroscopy for Biomedical Applications: Recent Advances and Future ChallengesLin, Linley Li, Alvarez-Puebla, Ramon, Liz-Marzán, Luis M., Trau, Matt, Wang, Jing, Fabris, Laura, Wang, Xiang, Liu, Guokun, Xu, Shuping, Han, Xiao Xia, Yang, Liangbao, Shen, Aiguo, Yang, Shikuan, Xu, Yikai, Li, Chunchun, Huang, Jinqing, Liu, Shao-Chuang, Huang, Jian-An, Srivastava, Indrajit, Li, Ming, Tian, Limei, Nguyen, Lam Bang Thanh, Bi, Xinyuan, Cialla-May, Dana, Matousek, Pavel, Stone, Nicholas, Carney, Randy P., Ji, Wei, Song, Wei ... Ye, Jian (2025). Surface-Enhanced Raman Spectroscopy for Biomedical Applications: Recent Advances and Future Challenges. ACS Applied Materials & Interfaces, 17 (11), 16287-16379. doi: 10.1021/acsami.4c17502 |
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2025 Journal Article Development and Application of Multivalent Nanobody-functionalized Plasmonic Probes in SERS Sensing PlatformsWang, Jing, Zhou, Quan, Lowry, Kym, Howard, Christopher B. and Trau, Matt (2025). Development and Application of Multivalent Nanobody-functionalized Plasmonic Probes in SERS Sensing Platforms. Biosensors and Bioelectronics, 278 117292, 117292. doi: 10.1016/j.bios.2025.117292 |
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2025 Journal Article High-throughput enrichment of functional disulfide-rich peptides by droplet microfluidicsXie, Jing, Yap, Kuok, de Veer, Simon J., Edwardraja, Selvakumar, Durek, Thomas, Trau, Matt, Craik, David J. and Wang, Conan K. (2025). High-throughput enrichment of functional disulfide-rich peptides by droplet microfluidics. Lab on a Chip, 25 (14), 3525-3536. doi: 10.1039/d5lc00261c |
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2024 Journal Article DIYNAFLUOR: an affordable DIY plug-and-play nucleic acid fluorometer for eDNA quantification in resource limited settingsAnderson, Will, Antaw, Fiach, Kenny, Sophie, Rupani, Harshita, Khamis, Ramlah, Constantin, Nicolas, Kumar, Vinay, Gemmell, Anna, Bell, Craig, Trau, Matt and Korbie, Darren (2024). DIYNAFLUOR: an affordable DIY plug-and-play nucleic acid fluorometer for eDNA quantification in resource limited settings. doi: 10.1101/2024.12.16.626200 |
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2024 Journal Article Post-acute sequelae of SARS-CoV-2 cardiovascular symptoms are associated with trace-level cytokines that affect cardiomyocyte functionSinclair, Jane E., Vedelago, Courtney, Ryan, Feargal J., Carney, Meagan, Redd, Meredith A., Lynn, Miriam A., Grubor-Bauk, Branka, Cao, Yuanzhao, Henders, Anjali K., Chew, Keng Yih, Gilroy, Deborah, Greaves, Kim, Labzin, Larisa, Ziser, Laura, Ronacher, Katharina, Wallace, Leanne M., Zhang, Yiwen, Macauslane, Kyle, Ellis, Daniel J., Rao, Sudha, Burr, Lucy, Bain, Amanda, Karawita, Anjana, Schulz, Benjamin L., Li, Junrong, Lynn, David J., Palpant, Nathan, Wuethrich, Alain, Trau, Matt and Short, Kirsty R. (2024). Post-acute sequelae of SARS-CoV-2 cardiovascular symptoms are associated with trace-level cytokines that affect cardiomyocyte function. Nature Microbiology, 9 (12), 1-13. doi: 10.1038/s41564-024-01838-z |
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2024 Journal Article Glycan profiling in small extracellular vesicles with a SERS microfluidic biosensor identifies early malignant development in lung cancerZhou, Quan, Niu, Xueming, Zhang, Zhen, O'Byrne, Kenneth, Kulasinghe, Arutha, Fielding, David, Möller, Andreas, Wuethrich, Alain, Lobb, Richard J. and Trau, Matt (2024). Glycan profiling in small extracellular vesicles with a SERS microfluidic biosensor identifies early malignant development in lung cancer. Advanced Science, 11 (33) 2401818, 1-12. doi: 10.1002/advs.202401818 |
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2024 Journal Article A mesoporous gold sensor unveils phospho PD-L1 in extracellular vesicles as a proxy for PD-L1 expression in lung cancer tissueShanmugasundaram, Karthik B., Ahmed, Emtiaz, Miao, Xinzhe, Kulasinghe, Arutha, Fletcher, James A., Monkman, James, Mainwaring, Paul, Masud, Mostafa Kamal, Park, Hyeongyu, Hossain, Md Shahriar A., Yamauchi, Yusuke, Sina, Abu A. I., O’Byrne, Kenneth, Wuethrich, Alain and Trau, Matt (2024). A mesoporous gold sensor unveils phospho PD-L1 in extracellular vesicles as a proxy for PD-L1 expression in lung cancer tissue. ACS Sensors, 9 (6), 3009-3016. doi: 10.1021/acssensors.4c00192 |
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2024 Journal Article Analysis of secreted small extracellular vesicles from activated human microglial cell lines reveals distinct pro‐ and anti‐inflammatory proteomic profilesNiu, Xueming, Zhang, Zhen, Zhou, Quan, Wuethrich, Alain, Lobb, Richard and Trau, Matt (2024). Analysis of secreted small extracellular vesicles from activated human microglial cell lines reveals distinct pro‐ and anti‐inflammatory proteomic profiles. Proteomics, 24 (11) 2300094, 1-13. doi: 10.1002/pmic.202300094 |
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2024 Journal Article LowTempGAL: a highly responsive low temperature-inducible GAL system in Saccharomyces cerevisiaeLu, Zeyu, Shen, Qianyi, Bandari, Naga Chandra, Evans, Samuel, Mcdonnell, Liam, Liu, Lian, Jin, Wanli, Luna-Flores, Carlos Horacio, Collier, Thomas, Talbo, Gert, Mccubbin, Tim, Esquirol, Lygie, Myers, Chris, Trau, Matt, Dumsday, Geoff, Speight, Robert, Howard, Christopher B., Vickers, Claudia E. and Peng, Bingyin (2024). LowTempGAL: a highly responsive low temperature-inducible GAL system in Saccharomyces cerevisiae. Nucleic Acids Research, 52 (12) gkae460, 7367-7383. doi: 10.1093/nar/gkae460 |
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2024 Journal Article Molecular stratification and treatment monitoring of lung cancer using a small extracellular vesicle-activated nanocavity architectureLi, Junrong, Li, Meiqin, Wuethrich, Alain, Guan, Rui, Zhao, Lihui, Hu, Cong, Trau, Matt and Sun, Yao (2024). Molecular stratification and treatment monitoring of lung cancer using a small extracellular vesicle-activated nanocavity architecture. Analytical Chemistry, 96 (19), 7651-7660. doi: 10.1021/acs.analchem.4c00558 |
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2024 Journal Article A mesoporous gold biosensor to investigate immune checkpoint protein heterogeneity in single lung cancer cellsAhmed, Emtiaz, Masud, Mostafa Kamal, Komatineni, Prathyusha, Dey, Shuvashis, Lobb, Richard, Hossain, Md Shahriar A., Möller, Andreas, Yamauchi, Yusuke, Sina, Abu Ali Ibn and Trau, Matt (2024). A mesoporous gold biosensor to investigate immune checkpoint protein heterogeneity in single lung cancer cells. Biosensors and Bioelectronics, 249 115984, 1-9. doi: 10.1016/j.bios.2023.115984 |
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2024 Journal Article Cancer‐on‐chip and integrative tumor microenvironment sensor technologies for progressing precision radiotherapyDey, Shuvashis, Kinoshita, Masaki, Puttick, Simon, Rose, Stephen, Trau, Matt, Roberts, Matthew J. and Koo, Kevin M. (2024). Cancer‐on‐chip and integrative tumor microenvironment sensor technologies for progressing precision radiotherapy. Advanced Sensor Research, 3 (7) 2300193. doi: 10.1002/adsr.202300193 |
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2024 Journal Article High accuracy of clinical verification of electrohydrodynamic-driven nanobox-on-mirror platform for molecular identification of respiratory virusesLi, Junrong, Guan, Rui, Wuethrich, Alain, Yan, Mingzhe, Cheng, Jing, Liu, Guorong, Zhan, Jianbo, Trau, Matt and Sun, Yao (2024). High accuracy of clinical verification of electrohydrodynamic-driven nanobox-on-mirror platform for molecular identification of respiratory viruses. Analytical Chemistry, 96 (11), 4495-4504. doi: 10.1021/acs.analchem.3c05120 |
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2024 Journal Article Digital platforms enabling single-molecule analysis for cancer detectionLi, Junrong, Zhang, Zhen, Trau, Matt and Wuethrich, Alain (2024). Digital platforms enabling single-molecule analysis for cancer detection. TrAC Trends in Analytical Chemistry, 171 117502, 1-12. doi: 10.1016/j.trac.2023.117502 |
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2024 Journal Article Tracking the EMT-like phenotype switching during targeted therapy in melanoma by analyzing extracellular vesicle phenotypesZhou, Quan, Wang, Jing, Zhang, Zhen, Wuethrich, Alain, Lobb, Richard J. and Trau, Matt (2024). Tracking the EMT-like phenotype switching during targeted therapy in melanoma by analyzing extracellular vesicle phenotypes. Biosensors and Bioelectronics, 244 115819, 1-10. doi: 10.1016/j.bios.2023.115819 |
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2024 Journal Article Defining the relationship between cellular and extracellular vesicle (EV) content in breast cancer via an integrative multi‐omic analysisLane, Rebecca E., Korbie, Darren, Khanna, Kum Kum, Mohamed, Ahmed, Hill, Michelle M. and Trau, Matt (2024). Defining the relationship between cellular and extracellular vesicle (EV) content in breast cancer via an integrative multi‐omic analysis. Proteomics, 24 (11) e2300089, 1-18. doi: 10.1002/pmic.202300089 |
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2024 Journal Article A perspective about the potential use of nanotechnology to monitor immune correlates of the clinical course of major mood disordersWuethrich, Alain, Crouse, Jacob J., Vedelago, Courtney, Zhang, Yiwen, Farokhinejad, Fahimeh, Hickie, Ian B. and Trau, Matt (2024). A perspective about the potential use of nanotechnology to monitor immune correlates of the clinical course of major mood disorders. Research Directions: Depression, 1 e20, 1-4. doi: 10.1017/dep.2024.3 |
