Skip to menu Skip to content Skip to footer

2025

Journal Article

Conventional techniques and emerging nanotechnologies for early detection of cancer metastasis via epithelial-mesenchymal transition monitoring

Zhang, Zhen, Wang, Jing, Wuethrich, Alain and Trau, Matt (2025). Conventional techniques and emerging nanotechnologies for early detection of cancer metastasis via epithelial-mesenchymal transition monitoring. National Science Review, 12 (3) nwae452, 1-17. doi: 10.1093/nsr/nwae452

Conventional techniques and emerging nanotechnologies for early detection of cancer metastasis via epithelial-mesenchymal transition monitoring

2025

Journal Article

Development and Application of Multivalent Nanobody-functionalized Plasmonic Probes in SERS Sensing Platforms

Wang, Jing, Zhou, Quan, Lowry, Kym, Howard, Christopher B. and Trau, Matt (2025). Development and Application of Multivalent Nanobody-functionalized Plasmonic Probes in SERS Sensing Platforms. Biosensors and Bioelectronics, 278 117292, 117292. doi: 10.1016/j.bios.2025.117292

Development and Application of Multivalent Nanobody-functionalized Plasmonic Probes in SERS Sensing Platforms

2024

Journal Article

DIYNAFLUOR: an affordable DIY plug-and-play nucleic acid fluorometer for eDNA quantification in resource limited settings

Anderson, Will, Antaw, Fiach, Kenny, Sophie, Rupani, Harshita, Khamis, Ramlah, Constantin, Nicolas, Kumar, Vinay, Gemmell, Anna, Bell, Craig, Trau, Matt and Korbie, Darren (2024). DIYNAFLUOR: an affordable DIY plug-and-play nucleic acid fluorometer for eDNA quantification in resource limited settings. doi: 10.1101/2024.12.16.626200

DIYNAFLUOR: an affordable DIY plug-and-play nucleic acid fluorometer for eDNA quantification in resource limited settings

2024

Journal Article

Post-acute sequelae of SARS-CoV-2 cardiovascular symptoms are associated with trace-level cytokines that affect cardiomyocyte function

Sinclair, Jane E., Vedelago, Courtney, Ryan, Feargal J., Carney, Meagan, Redd, Meredith A., Lynn, Miriam A., Grubor-Bauk, Branka, Cao, Yuanzhao, Henders, Anjali K., Chew, Keng Yih, Gilroy, Deborah, Greaves, Kim, Labzin, Larisa, Ziser, Laura, Ronacher, Katharina, Wallace, Leanne M., Zhang, Yiwen, Macauslane, Kyle, Ellis, Daniel J., Rao, Sudha, Burr, Lucy, Bain, Amanda, Karawita, Anjana, Schulz, Benjamin L., Li, Junrong, Lynn, David J., Palpant, Nathan, Wuethrich, Alain, Trau, Matt and Short, Kirsty R. (2024). Post-acute sequelae of SARS-CoV-2 cardiovascular symptoms are associated with trace-level cytokines that affect cardiomyocyte function. Nature Microbiology, 9 (12), 1-13. doi: 10.1038/s41564-024-01838-z

Post-acute sequelae of SARS-CoV-2 cardiovascular symptoms are associated with trace-level cytokines that affect cardiomyocyte function

2024

Journal Article

Glycan profiling in small extracellular vesicles with a SERS microfluidic biosensor identifies early malignant development in lung cancer

Zhou, Quan, Niu, Xueming, Zhang, Zhen, O'Byrne, Kenneth, Kulasinghe, Arutha, Fielding, David, Möller, Andreas, Wuethrich, Alain, Lobb, Richard J. and Trau, Matt (2024). Glycan profiling in small extracellular vesicles with a SERS microfluidic biosensor identifies early malignant development in lung cancer. Advanced Science, 11 (33) 2401818, 1-12. doi: 10.1002/advs.202401818

Glycan profiling in small extracellular vesicles with a SERS microfluidic biosensor identifies early malignant development in lung cancer

2024

Journal Article

A mesoporous gold sensor unveils phospho PD-L1 in extracellular vesicles as a proxy for PD-L1 expression in lung cancer tissue

Shanmugasundaram, Karthik B., Ahmed, Emtiaz, Miao, Xinzhe, Kulasinghe, Arutha, Fletcher, James A., Monkman, James, Mainwaring, Paul, Masud, Mostafa Kamal, Park, Hyeongyu, Hossain, Md Shahriar A., Yamauchi, Yusuke, Sina, Abu A. I., O’Byrne, Kenneth, Wuethrich, Alain and Trau, Matt (2024). A mesoporous gold sensor unveils phospho PD-L1 in extracellular vesicles as a proxy for PD-L1 expression in lung cancer tissue. ACS Sensors, 9 (6), 3009-3016. doi: 10.1021/acssensors.4c00192

A mesoporous gold sensor unveils phospho PD-L1 in extracellular vesicles as a proxy for PD-L1 expression in lung cancer tissue

2024

Journal Article

Analysis of secreted small extracellular vesicles from activated human microglial cell lines reveals distinct pro‐ and anti‐inflammatory proteomic profiles

Niu, Xueming, Zhang, Zhen, Zhou, Quan, Wuethrich, Alain, Lobb, Richard and Trau, Matt (2024). Analysis of secreted small extracellular vesicles from activated human microglial cell lines reveals distinct pro‐ and anti‐inflammatory proteomic profiles. Proteomics, 24 (11) 2300094, 1-13. doi: 10.1002/pmic.202300094

Analysis of secreted small extracellular vesicles from activated human microglial cell lines reveals distinct pro‐ and anti‐inflammatory proteomic profiles

2024

Journal Article

LowTempGAL: a highly responsive low temperature-inducible GAL system in Saccharomyces cerevisiae

Lu, Zeyu, Shen, Qianyi, Bandari, Naga Chandra, Evans, Samuel, Mcdonnell, Liam, Liu, Lian, Jin, Wanli, Luna-Flores, Carlos Horacio, Collier, Thomas, Talbo, Gert, Mccubbin, Tim, Esquirol, Lygie, Myers, Chris, Trau, Matt, Dumsday, Geoff, Speight, Robert, Howard, Christopher B., Vickers, Claudia E. and Peng, Bingyin (2024). LowTempGAL: a highly responsive low temperature-inducible GAL system in Saccharomyces cerevisiae. Nucleic Acids Research, 52 (12) gkae460, 7367-7383. doi: 10.1093/nar/gkae460

LowTempGAL: a highly responsive low temperature-inducible GAL system in Saccharomyces cerevisiae

2024

Journal Article

Molecular stratification and treatment monitoring of lung cancer using a small extracellular vesicle-activated nanocavity architecture

Li, Junrong, Li, Meiqin, Wuethrich, Alain, Guan, Rui, Zhao, Lihui, Hu, Cong, Trau, Matt and Sun, Yao (2024). Molecular stratification and treatment monitoring of lung cancer using a small extracellular vesicle-activated nanocavity architecture. Analytical Chemistry, 96 (19), 7651-7660. doi: 10.1021/acs.analchem.4c00558

Molecular stratification and treatment monitoring of lung cancer using a small extracellular vesicle-activated nanocavity architecture

2024

Journal Article

A mesoporous gold biosensor to investigate immune checkpoint protein heterogeneity in single lung cancer cells

Ahmed, Emtiaz, Masud, Mostafa Kamal, Komatineni, Prathyusha, Dey, Shuvashis, Lobb, Richard, Hossain, Md Shahriar A., Möller, Andreas, Yamauchi, Yusuke, Sina, Abu Ali Ibn and Trau, Matt (2024). A mesoporous gold biosensor to investigate immune checkpoint protein heterogeneity in single lung cancer cells. Biosensors and Bioelectronics, 249 115984, 1-9. doi: 10.1016/j.bios.2023.115984

A mesoporous gold biosensor to investigate immune checkpoint protein heterogeneity in single lung cancer cells

2024

Journal Article

Cancer‐on‐chip and integrative tumor microenvironment sensor technologies for progressing precision radiotherapy

Dey, Shuvashis, Kinoshita, Masaki, Puttick, Simon, Rose, Stephen, Trau, Matt, Roberts, Matthew J. and Koo, Kevin M. (2024). Cancer‐on‐chip and integrative tumor microenvironment sensor technologies for progressing precision radiotherapy. Advanced Sensor Research, 3 (7) 2300193. doi: 10.1002/adsr.202300193

Cancer‐on‐chip and integrative tumor microenvironment sensor technologies for progressing precision radiotherapy

2024

Journal Article

High accuracy of clinical verification of electrohydrodynamic-driven nanobox-on-mirror platform for molecular identification of respiratory viruses

Li, Junrong, Guan, Rui, Wuethrich, Alain, Yan, Mingzhe, Cheng, Jing, Liu, Guorong, Zhan, Jianbo, Trau, Matt and Sun, Yao (2024). High accuracy of clinical verification of electrohydrodynamic-driven nanobox-on-mirror platform for molecular identification of respiratory viruses. Analytical Chemistry, 96 (11), 4495-4504. doi: 10.1021/acs.analchem.3c05120

High accuracy of clinical verification of electrohydrodynamic-driven nanobox-on-mirror platform for molecular identification of respiratory viruses

2024

Journal Article

Digital platforms enabling single-molecule analysis for cancer detection

Li, Junrong, Zhang, Zhen, Trau, Matt and Wuethrich, Alain (2024). Digital platforms enabling single-molecule analysis for cancer detection. TrAC Trends in Analytical Chemistry, 171 117502, 1-12. doi: 10.1016/j.trac.2023.117502

Digital platforms enabling single-molecule analysis for cancer detection

2024

Journal Article

Tracking the EMT-like phenotype switching during targeted therapy in melanoma by analyzing extracellular vesicle phenotypes

Zhou, Quan, Wang, Jing, Zhang, Zhen, Wuethrich, Alain, Lobb, Richard J. and Trau, Matt (2024). Tracking the EMT-like phenotype switching during targeted therapy in melanoma by analyzing extracellular vesicle phenotypes. Biosensors and Bioelectronics, 244 115819, 1-10. doi: 10.1016/j.bios.2023.115819

Tracking the EMT-like phenotype switching during targeted therapy in melanoma by analyzing extracellular vesicle phenotypes

2024

Journal Article

Defining the relationship between cellular and extracellular vesicle (EV) content in breast cancer via an integrative multi‐omic analysis

Lane, Rebecca E., Korbie, Darren, Khanna, Kum Kum, Mohamed, Ahmed, Hill, Michelle M. and Trau, Matt (2024). Defining the relationship between cellular and extracellular vesicle (EV) content in breast cancer via an integrative multi‐omic analysis. Proteomics, 24 (11) e2300089, 1-18. doi: 10.1002/pmic.202300089

Defining the relationship between cellular and extracellular vesicle (EV) content in breast cancer via an integrative multi‐omic analysis

2024

Journal Article

A perspective about the potential use of nanotechnology to monitor immune correlates of the clinical course of major mood disorders

Wuethrich, Alain, Crouse, Jacob J., Vedelago, Courtney, Zhang, Yiwen, Farokhinejad, Fahimeh, Hickie, Ian B. and Trau, Matt (2024). A perspective about the potential use of nanotechnology to monitor immune correlates of the clinical course of major mood disorders. Research Directions: Depression, 1 e20, 1-4. doi: 10.1017/dep.2024.3

A perspective about the potential use of nanotechnology to monitor immune correlates of the clinical course of major mood disorders

2023

Journal Article

Integration of yeast episomal/integrative plasmid causes genotypic and phenotypic diversity and improved sesquiterpene production in metabolically engineered Saccharomyces cerevisiae

Peng, Bingyin, Weintraub, Sarah J., Lu, Zeyu, Evans, Samuel, Shen, Qianyi, McDonnell, Liam, Plan, Manuel, Collier, Thomas, Cheah, Li Chen, Ji, Lei, Howard, Christopher B., Anderson, Will, Trau, Matt, Dumsday, Geoff, Bredeweg, Erin L., Young, Eric M., Speight, Robert and Vickers, Claudia E. (2023). Integration of yeast episomal/integrative plasmid causes genotypic and phenotypic diversity and improved sesquiterpene production in metabolically engineered Saccharomyces cerevisiae. ACS Synthetic Biology, 13 (1), 141-156. doi: 10.1021/acssynbio.3c00363

Integration of yeast episomal/integrative plasmid causes genotypic and phenotypic diversity and improved sesquiterpene production in metabolically engineered Saccharomyces cerevisiae

2023

Journal Article

Multiplex SERS-lectin-immunoassay for esophageal adenocarcinoma screening

Khamis, Ramlah, Shanmugasundaram, Karthik B., Zhou, Quan, Lu, Jennifer, Zhang, Zhen, Hill, Michelle M., Sina, Abu Ali Ibn, Trau, Matt and Wuethrich, Alain (2023). Multiplex SERS-lectin-immunoassay for esophageal adenocarcinoma screening. ACS Applied Nano Materials, 6 (21), 20190-20197. doi: 10.1021/acsanm.3c03987

Multiplex SERS-lectin-immunoassay for esophageal adenocarcinoma screening

2023

Journal Article

Profiling proteomics responses to hexokinase-II depletion in terpene-producing Saccharomyces cerevisiae

Lu, Zeyu, Shen, Qianyi, Liu, Lian, Talbo, Gert, Speight, Robert, Trau, Matt, Dumsday, Geoff, Howard, Christopher B., Vickers, Claudia E. and Peng, Bingyin (2023). Profiling proteomics responses to hexokinase-II depletion in terpene-producing Saccharomyces cerevisiae. Engineering Microbiology, 3 (3) 100079, 100079. doi: 10.1016/j.engmic.2023.100079

Profiling proteomics responses to hexokinase-II depletion in terpene-producing Saccharomyces cerevisiae

2023

Journal Article

Erratum: Correction: Plasma extracellular vesicle phenotyping for the differentiation of early-stage lung cancer and benign lung diseases (Nanoscale horizons (2023) 8 6 (746-758))

Yuan, Liwen, Chen, Yanpin, Ke, Longfeng, Zhou, Quan, Chen, Jiayou, Fan, Min, Wuethrich, Alain, Trau, Matt and Wang, Jing (2023). Erratum: Correction: Plasma extracellular vesicle phenotyping for the differentiation of early-stage lung cancer and benign lung diseases (Nanoscale horizons (2023) 8 6 (746-758)). Nanoscale horizons, 8 (9) d3nh90028b, 1288-1289. doi: 10.1039/d3nh90028b

Erratum: Correction: Plasma extracellular vesicle phenotyping for the differentiation of early-stage lung cancer and benign lung diseases (Nanoscale horizons (2023) 8 6 (746-758))