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2016 Journal Article Iron and non-alcoholic fatty liver diseaseBritton, Laurence J., Subramaniam, V. Nathan and Crawford, Darrell H. G. (2016). Iron and non-alcoholic fatty liver disease. World Journal of Gastroenterology, 22 (36), 8112-8122. doi: 10.3748/wjg.v22.i36.8112 |
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2016 Journal Article Hematopoietic deletion of transferrin receptor 2 in mice leads to a block in erythroid differentiation during iron-deficient anemiaRishi, Gautam, Secondes, Eriza S., Wallace, Daniel F. and Subramaniam, V. Nathan (2016). Hematopoietic deletion of transferrin receptor 2 in mice leads to a block in erythroid differentiation during iron-deficient anemia. American Journal of Hematology, 91 (8), 812-818. doi: 10.1002/ajh.24417 |
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2016 Journal Article Pocket-sized iron regulators: One size fits all?Subramaniam, V. Nathan (2016). Pocket-sized iron regulators: One size fits all?. Blood, 128 (2), 153-154. doi: 10.1182/blood-2016-05-716043 |
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2016 Journal Article Probiotics modify tight-junction proteins in an animal model of nonalcoholic fatty liver diseaseBriskey, David, Heritage, Mandy, Jaskowski, Lesley-Anne, Peake, Jonathan, Gobe, Glenda, Subramaniam, V. Nathan, Crawford, Darrell, Campbell, Catherine and Vitetta, Luis (2016). Probiotics modify tight-junction proteins in an animal model of nonalcoholic fatty liver disease. Therapeutic Advances in Gastroenterology, 9 (4), 463-472. doi: 10.1177/1756283X16645055 |
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2016 Journal Article Heterozygous Hfe gene deletion leads to impaired glucose homeostasis, but not liver injury in mice fed a high-calorie dietBritton, Laurence, Jaskowski, Lesley, Bridle, Kim, Santrampurwala, Nishreen, Reiling, Janske, Musgrave, Nick, Subramaniam, V. Nathan and Crawford, Darrell (2016). Heterozygous Hfe gene deletion leads to impaired glucose homeostasis, but not liver injury in mice fed a high-calorie diet. Physiological Reports, 4 (12) e12837, e12837. doi: 10.14814/phy2.12837 |
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2016 Journal Article The global prevalence of HFE and non-HFE hemochromatosis estimated from analysis of next-generation sequencing dataWallace, Daniel F. and Subramaniam, V. Nathan (2016). The global prevalence of HFE and non-HFE hemochromatosis estimated from analysis of next-generation sequencing data. Genetics in Medicine, 18 (6), 618-626. doi: 10.1038/gim.2015.140 |
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2016 Journal Article ReplyMcLaren, Christine E., Barton, James C., Subramaniam, V. Nathan, Ramm, Grant A., Phatak, Pradyumna D., Emond, Mary J., Gurrin, Lyle C., Adams, Paul C., Powell, Lawrie W., Anderson, Gregory J. and McLaren, Gordon D. (2016). Reply. Hepatology, 63 (6), 2058-2060. doi: 10.1002/hep.28479 |
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2016 Journal Article GNPAT variant is not associated with severe iron overload in Irish C282Y homozygotes REPLYMcLaren, Christine E., Barton, James C., Phatak, Pradyumna D., Emond, Mary J., Subramaniam, V. Nathan, Gurrin, Lyle C., Adams, Paul C., Powell, Lawrie W., Ramm, Grant A., Anderson, Gregory J. and McLaren, Gordon D. (2016). GNPAT variant is not associated with severe iron overload in Irish C282Y homozygotes REPLY. Hepatology, 63 (6), 2056-2057. doi: 10.1002/hep.28260 |
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2016 Journal Article Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeuticsKalinowski, Danuta S., Stefani, Christian, Toyokuni, Shinya, Ganz, Tomas, Anderson, Gregory J., Subramaniam, Nathan V., Trinder, Debbie, Olynyk, John K., Chua, Anita, Jansson, Patric J., Sahni, Sumit, Lane, Darius J. R., Merlot, Angelica M., Kovacevic, Zaklina, Huang, Michael L. H., Lee, C. Soon and Richardson, Des R. (2016). Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1863 (4), 727-748. doi: 10.1016/j.bbamcr.2016.01.026 |
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2016 Conference Publication Differences in Clinical Manifestations of Hemochromatosis in Hfe C282Y Homozygotes with Extreme High and Low Iron PhenotypesMcLaren, G. D., Powell, L. W., Phatak, P. D., Barton, J. C., Adams, P. C., Subramaniam, V. N., Gurrin, L. C., Phillips, J. D., Parker, C., Allen, K. J., Chen, W-P, Emond, M. J., Nickerson, D. A., Ramm, G. A., Anderson, G. J. and McLaren, C. E. (2016). Differences in Clinical Manifestations of Hemochromatosis in Hfe C282Y Homozygotes with Extreme High and Low Iron Phenotypes. HOBOKEN: W B SAUNDERS CO. |
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2016 Journal Article Normal systemic iron homeostasis in mice with macrophage-specific deletion of transferrin receptor 2Rishi,Gautam, Secondes, Eriza S., Wallace, Daniel F. and Subramaniam, V. Nathan (2016). Normal systemic iron homeostasis in mice with macrophage-specific deletion of transferrin receptor 2. American Journal of Physiology - Gastrointestinal and Liver Physiology, 310 (3), G171-G180. doi: 10.1152/ajpgi.00291.2015 |
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2016 Conference Publication Iron and Erythropoiesis: a Novel Role for Transferrin Receptor 2 in Stress ErythropoiesisRishi, Gautam, Wallace, Daniel, Secondes, Eriza and Subramaniam, Nathan (2016). Iron and Erythropoiesis: a Novel Role for Transferrin Receptor 2 in Stress Erythropoiesis. WILEY-BLACKWELL. |
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2016 Conference Publication Non-Hfe Haemochromatosis: Estimation of the Global Prevalence From Analysis of Next-Generation Sequencing DataWallace, Daniel and Subramaniam, V. Nathan (2016). Non-Hfe Haemochromatosis: Estimation of the Global Prevalence From Analysis of Next-Generation Sequencing Data. WILEY-BLACKWELL. |
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2016 Conference Publication Exome Sequencing in Hfe C282Y Homozygotes with Extreme Hepatic Iron Overload Reveals Modifying Genes for the Development of CirrhosisEmond, Mary, McLaren, Christine, Louie, Tin, Wu, Jie, Powell, Lawrie, Phatak, Pradyumna, Barton, James, Adams, Paul, Gurrin, Lyle, Phillips, John, Parker, Charles, Allen, Katrina, Nickerson, Deborah, Anderson, Gregory, Subramaniam, Nathan, McLaren, Gordon and Ramm, Grant (2016). Exome Sequencing in Hfe C282Y Homozygotes with Extreme Hepatic Iron Overload Reveals Modifying Genes for the Development of Cirrhosis. WILEY-BLACKWELL. |
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2016 Conference Publication Development of peptide therapeutics for iron disordersGoncalves, Daniela, Rishi, Gautam, Aliyanto, Randy, Rosengren, Johan, Subramaniam, Nathan, Frazer, David and Clark, Richard (2016). Development of peptide therapeutics for iron disorders. 6th Meeting of the International BioIron Society, Zhejiang University, Hangzhou, China, 8-10 September 2015. Hoboken, NJ, United States: John Wiley & Sons. |
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2015 Journal Article Endofin, a novel BMP-SMAD regulator of the iron-regulatory hormone, hepcidinGoh, Justin B., Wallace, Daniel F., Hong, Wanjin and Subramaniam, V. Nathan (2015). Endofin, a novel BMP-SMAD regulator of the iron-regulatory hormone, hepcidin. Scientific Reports, 5 (1) 13986, 13986.1-13986.12. doi: 10.1038/srep13986 |
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2015 Journal Article Exome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overloadMcLaren, Christine E., Emond, Mary J., Subramaniam, V. Nathan, Phatak, Pradyumna D., Barton, James C., Adams, Paul C., Goh, Justin B., McDonald, Cameron J., Powell, Lawrie W., Gurrin, Lyle C., Allen, Katrina J., Nickerson, Deborah A., Louie, Tin, Ramm, Grant A., Anderson, Gregory J. and McLaren, Gordon D. (2015). Exome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overload. Hepatology, 62 (2), 429-439. doi: 10.1002/hep.27711 |
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2015 Journal Article Next-generation sequencing: Application of a novel platform to analyze atypical iron disordersMcDonald, Cameron J., Ostini, Lesa., Wallace, Daniel F., Lyons, Alison., Crawford, Darrell H.G. and Subramaniam, V. Nathan. (2015). Next-generation sequencing: Application of a novel platform to analyze atypical iron disorders. Journal of Hepatology, 63 (5), 1288-1293. doi: 10.1016/j.jhep.2015.06.027 |
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2015 Journal Article Analysis of IL-22 contribution to hepcidin induction and hypoferremia during the response to LPS in vivoWallace, Daniel F. and Subramaniam, V. Nathan (2015). Analysis of IL-22 contribution to hepcidin induction and hypoferremia during the response to LPS in vivo. International Immunology, 27 (6), 281-287. doi: 10.1093/intimm/dxu144 |
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2015 Journal Article Lack of efficacy of mTOR inhibitors and ACE pathway inhibitors as antifibrotic agents in evolving and established fibrosis in Mdr2-/- miceBridle, Kim R., Sobbe, Amy L., de Guzman, C. Erika, Santrampurwala, Nishreen, Jaskowski, Lesley A., Clouston, Andrew D., Campbell, Catherine M., Nathan Subramaniam, V. and Crawford, Darrell H. G. (2015). Lack of efficacy of mTOR inhibitors and ACE pathway inhibitors as antifibrotic agents in evolving and established fibrosis in Mdr2-/- mice. Liver International, 35 (4), 1451-1463. doi: 10.1111/liv.12494 |
