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2020 Journal Article Molybdenum enzymes and how they support virulence in pathogenic bacteriaZhong, Qifeng, Kobe, Bostjan and Kappler, Ulrike (2020). Molybdenum enzymes and how they support virulence in pathogenic bacteria. Frontiers in Microbiology, 11 615860, 1-23. doi: 10.3389/fmicb.2020.615860 |
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2020 Journal Article Peptide methionine sulfoxide reductase from Haemophilus influenzae is required for protection against HOCl and affects the host response to infectionNasreen, Marufa, Dhouib, Rabeb, Hosmer, Jennifer, Wijesinghe, Hewa Godage Sithija, Fletcher, Aidan, Mahawar, Manish, Essilfie, Ama-Tawiah, Blackall, Patrick J., McEwan, Alastair G. and Kappler, Ulrike (2020). Peptide methionine sulfoxide reductase from Haemophilus influenzae is required for protection against HOCl and affects the host response to infection. ACS Infectious Diseases, 6 (7), 1928-1939. doi: 10.1021/acsinfecdis.0c00242 |
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2020 Journal Article Haemophilus influenzae glucose catabolism leading to production of the immunometabolite acetate has a key contribution to the host airway-pathogen interplayLópez-López, Nahikari, Euba, Begoña, Hill, Julian, Dhouib, Rabeb, Caballero, Lucı A, Leiva, José, Hosmer, Jennifer, Cuesta, Sergio, Ramos-Vivas, José, Díez-Martínez, Roberto, Schirra, Horst Joachim, Blank, Lars M., Kappler, Ulrike and Garmendia, Junkal (2020). Haemophilus influenzae glucose catabolism leading to production of the immunometabolite acetate has a key contribution to the host airway-pathogen interplay. ACS Infectious Diseases, 6 (3), 406-421. doi: 10.1021/acsinfecdis.9b00359 |
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2019 Journal Article New insights into the molecular physiology of sulfoxide reduction in bacteriaKappler, Ulrike, Nasreen, Marufa and McEwan, Alastair (2019). New insights into the molecular physiology of sulfoxide reduction in bacteria. Advances in Microbial Physiology, 75, 1-51. doi: 10.1016/bs.ampbs.2019.05.001 |
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2019 Journal Article Control of bacterial sulfite detoxification by conserved and species-specific regulatory circuitsTan, Yi Jie Chelsea, Zhao, Chengzhi, Nasreen, Marufa, O'Rourke, Leo, Dhouib, Rabeb, Roberts, Leah, Wan, Ying, Beatson, Scott A. and Kappler, Ulrike (2019). Control of bacterial sulfite detoxification by conserved and species-specific regulatory circuits. Frontiers in Microbiology, 10 (MAY) 960, 960. doi: 10.3389/fmicb.2019.00960 |
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2019 Journal Article Metabolic analyses reveal common adaptations in two invasive Haemophilus influenzae strainsMuda, Noor Marian, Nasreen, Marufa, Dhouib, Rabeb, Hosmer, Jennifer, Hill, Julian, Mahawar, Manish, Schirra, Horst Joachim, McEwan, Alastair G. and Kappler, Ulrike (2019). Metabolic analyses reveal common adaptations in two invasive Haemophilus influenzae strains. Pathogens and Disease, 77 (2) ftz015. doi: 10.1093/femspd/ftz015 |
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2018 Journal Article Antifungal benzo[b]thiophene 1,1-dioxide IMPDH inhibitors exhibit pan-assay interference (PAINS) profilesKummari, Lalith K., Butler, Mark S., Furlong, Emily, Blundell, Ross, Nouwens, Amanda, Silva, Alberto B., Kappler, Ulrike, Fraser, James A., Kobe, Bostjan, Cooper, Matthew A. and Robertson, Avril A.B. (2018). Antifungal benzo[b]thiophene 1,1-dioxide IMPDH inhibitors exhibit pan-assay interference (PAINS) profiles. Bioorganic and Medicinal Chemistry, 26 (20), 5408-5419. doi: 10.1016/j.bmc.2018.09.004 |
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2018 Journal Article The central active site arginine in sulfite oxidizing enzymes alters kinetic properties by controlling electron transfer and redox interactionsHsiao, Ju-Chun, McGrath, Aaron P., Kielmann, Linda, Kalimuthu, Palraj, Darain, Farzana, Bernhardt, Paul V., Harmer, Jeffrey, Lee, Mihwa, Meyers, Kimberley, Maher, Megan J. and Kappler, Ulrike (2018). The central active site arginine in sulfite oxidizing enzymes alters kinetic properties by controlling electron transfer and redox interactions. Biochimica et Biophysica Acta - Bioenergetics, 1859 (1), 19-27. doi: 10.1016/j.bbabio.2017.10.001 |
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2017 Journal Article Bioelectrocatalysis of sulfite dehydrogenase from Sinorhizobium meliloti with its physiological cytochrome electron partnerKalimuthu, Palraj, Hsiao, Ju-Chun, Nair, Remya Purushothaman, Kappler, Ulrike and Bernhardt, Paul V. (2017). Bioelectrocatalysis of sulfite dehydrogenase from Sinorhizobium meliloti with its physiological cytochrome electron partner. ChemElectroChem, 4 (12), 3163-3170. doi: 10.1002/celc.201700838 |
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2017 Journal Article Cryptococcus neoformans ADS lyase is an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug designChitty, Jessica L., Blake, Kirsten L., Blundell, Ross D., Koh, Y. Q. Andre E., Thompson, Merinda, Robertson, Avril A. B., Butler, Mark S., Cooper, Matthew A., Kappler, Ulrike, Williams, Simon J., Kobe, Bostjan and Fraser, James A. (2017). Cryptococcus neoformans ADS lyase is an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug design. Journal of Biological Chemistry, 292 (28), 11829-11839. doi: 10.1074/jbc.M117.787994 |
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2017 Journal Article A unique large-scale undergraduate research experience in molecular systems biology for non-mathematics majorsKappler, Ulrike, Rowland, Susan L. and Pedwell, Rhianna K. (2017). A unique large-scale undergraduate research experience in molecular systems biology for non-mathematics majors. Biochemistry and Molecular Biolody Education, 45 (3), 235-248. doi: 10.1002/bmb.21033 |
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2017 Journal Article The ecology of acidophilic microorganisms in the corroding concrete sewer environmentLi, Xuan, Kappler, Ulrike, Jiang, Guangming and Bond, Philip L. (2017). The ecology of acidophilic microorganisms in the corroding concrete sewer environment. Frontiers in Microbiology, 8 (APR) 683, 683. doi: 10.3389/fmicb.2017.00683 |
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2017 Journal Article Sulfur compound oxidation and carbon co-assimilation in the haloalkaliphilic sulfur oxidizers Thioalkalivibrio versutus and Thioalkalimicrobium aerophilumAng, Wee Kiong, Mahbob, Maisarah, Dhouib, Rabeb and Kappler, Ulrike (2017). Sulfur compound oxidation and carbon co-assimilation in the haloalkaliphilic sulfur oxidizers Thioalkalivibrio versutus and Thioalkalimicrobium aerophilum. Research in Microbiology, 168 (3), 255-265. doi: 10.1016/j.resmic.2016.12.004 |
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2017 Journal Article Draft genome sequences of three nontypeable strains of Haemophilus influenzae, C188, R535, and 1200, isolated from different types of diseaseKappler, Ulrike, Dhouib, Rabeb, Nair, Remya Purushothaman and McEwan, Alastair G. (2017). Draft genome sequences of three nontypeable strains of Haemophilus influenzae, C188, R535, and 1200, isolated from different types of disease. Genome Announcements, 5 (12) e00035-17, e00035-17. doi: 10.1128/genomeA.00035-17 |
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2017 Journal Article GMP synthase is required for virulence factor production and infection by cryptococcus neoformansChitty, Jessica L., Tatzenko, Tayla L. , Williams, Simon J., Koh, Y. Q. Andre E., Corfield, Elizabeth C., Butler, Mark S., Robertson, Avril A. B., Cooper, Matthew A., Kappler, Ulrike, Kobe, Bostjan and Fraser, James A. (2017). GMP synthase is required for virulence factor production and infection by cryptococcus neoformans. Journal of Biological Chemistry, 292 (7), 3049-3059. doi: 10.1074/jbc.M116.767533 |
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2016 Journal Article A novel, molybdenum-containing methionine sulfoxide reductase supports survival of Haemophilus influenzae in an in vivo model of infectionDhouib, Rabeb, Othman, Dk. Seti Maimonah Pg, Lin, Victor, Lai, Xuanjie J., Wijesinghe, Hewa G. S., Essilfie, Ama-Tawiah, Davis, Amanda, Nasreen, Marufa, Bernhardt, Paul V., Hansbro, Philip M., McEwan, Alastair G. and Kappler, Ulrike (2016). A novel, molybdenum-containing methionine sulfoxide reductase supports survival of Haemophilus influenzae in an in vivo model of infection. Frontiers in Microbiology, 7 (NOV) 1743, 1743. doi: 10.3389/fmicb.2016.01743 |
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2016 Journal Article Disruption of de novo adenosine triphosphate (ATP) biosynthesis abolishes virulence in Cryptococcus neoformansBlundell, Ross D., Williams, Simon J., Arras, Samantha D. M., Chitty, Jessica L., Blake, Kirsten L., Ericsson, Daniel J., Tibrewal, Nidhi, Rohr, Jurgen, Koh, Y. Q. Andre, Kappler, Ulrike, Robertson, Avril A. B., Butler, Mark S., Cooper, Matthew A., Kobe, Bostjan and Fraser, James A. (2016). Disruption of de novo adenosine triphosphate (ATP) biosynthesis abolishes virulence in Cryptococcus neoformans. ACS Infectious Diseases, 2 (9), 651-663. doi: 10.1021/acsinfecdis.6b00121 |
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2016 Journal Article Complete genome sequence of the haloalkaliphilic, obligately chemolithoautotrophic thiosulfate and sulfide-oxidizing γ-proteobacterium Thioalkalimicrobium cyclicum type strain ALM 1 (DSM 14477T)Kappler, Ulrike, Davenport, Karen, Beatson, Scott, Lapidus, Alla, Pan, Chongle, Han, Cliff, Montero-Calasanz, Maria del Carmen, Land, Miriam, Hauser, Loren, Rohde, Manfred, Goeker, Markus, Ivanova, Natalia, Woyke, Tanja, Klenk, Hans-Peter and Kyrpides, Nikos C. (2016). Complete genome sequence of the haloalkaliphilic, obligately chemolithoautotrophic thiosulfate and sulfide-oxidizing γ-proteobacterium Thioalkalimicrobium cyclicum type strain ALM 1 (DSM 14477T). Standards in Genomic Sciences, 11 (38) 38, 1-12. doi: 10.1186/s40793-016-0162-x |
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2016 Journal Article Effects of mutations in active site heme ligands on the spectroscopic and catalytic properties of SoxAX cytochromesKilmartin, James R., Bernhardt, Paul V., Dhouib, Rabeb, Hanson, Graeme R., Riley, Mark J. and Kappler, Ulrike (2016). Effects of mutations in active site heme ligands on the spectroscopic and catalytic properties of SoxAX cytochromes. Journal of Inorganic Biochemistry, 162, 309-318. doi: 10.1016/j.jinorgbio.2016.04.015 |
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2015 Journal Article Structural basis of interprotein electron transfer in bacterial sulfite oxidationMcGrath, Aaron P., Laming, Elise L., Casas Garcia, G. Patricia, Kvansakul, Marc, Guss, J. Mitchell, Trewhella, Jill, Calmes, Benoit, Bernhardt, Paul V.,, Hanson, Graeme R.,, Kappler, Ulrike and Maher, Megan J. (2015). Structural basis of interprotein electron transfer in bacterial sulfite oxidation. eLife, 4 (e09066) e09066, 1-26. doi: 10.7554/eLife.09066 |
