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2017

Journal Article

Development of new gonadotropin-releasing hormone-modified dendrimer platforms with direct antiproliferative and gonadotropin releasing activity

Varamini, Pegah, Rafiee, Amirreza, Giddam, Ashwini Kumar, Mansfeld, Friederike M., Steyn, Frederik and Toth, Istvan (2017). Development of new gonadotropin-releasing hormone-modified dendrimer platforms with direct antiproliferative and gonadotropin releasing activity. Journal of Medicinal Chemistry, 60 (20), 8309-8320. doi: 10.1021/acs.jmedchem.6b01771

Development of new gonadotropin-releasing hormone-modified dendrimer platforms with direct antiproliferative and gonadotropin releasing activity

2017

Journal Article

Bivalent mucosal peptide vaccines administered using the LCP carrier system stimulate protective immune responses against Streptococcus pyogenes infection

Schulze, Kai, Ebensen, Thomas, Chandrudu, Saranya, Skwarczynski, Mariusz, Toth, Istvan, Olive, Colleen and Guzman, Carlos A (2017). Bivalent mucosal peptide vaccines administered using the LCP carrier system stimulate protective immune responses against Streptococcus pyogenes infection. Nanomedicine : nanotechnology, biology, and medicine, 13 (8), 2463-2474. doi: 10.1016/j.nano.2017.08.015

Bivalent mucosal peptide vaccines administered using the LCP carrier system stimulate protective immune responses against Streptococcus pyogenes infection

2017

Journal Article

Highly immunogenic trimethyl chitosan-based delivery system for intranasal lipopeptide vaccines against group A streptococcus

Marasini, Nirmal, Ghaffar, Khairunnisa Abdul, Giddam, Ashwini Kumar, Batzloff, Michael R., Good, Michael F., Skwarczynski, Mariusz and Toth, Istvan (2017). Highly immunogenic trimethyl chitosan-based delivery system for intranasal lipopeptide vaccines against group A streptococcus. Current Drug Delivery, 14 (5), 701-708. doi: 10.2174/1567201813666160721141322

Highly immunogenic trimethyl chitosan-based delivery system for intranasal lipopeptide vaccines against group A streptococcus

2017

Journal Article

The application of self-assembled nanostructures in peptide-based subunit vaccine development

Zhao, Guangzu, Chandrudu, Saranya, Skwarczynski, Mariusz and Toth, Istvan (2017). The application of self-assembled nanostructures in peptide-based subunit vaccine development. European Polymer Journal, 93, 670-681. doi: 10.1016/j.eurpolymj.2017.02.014

The application of self-assembled nanostructures in peptide-based subunit vaccine development

2017

Journal Article

Multifunctional peptide-lipid nanocomplexes for efficient targeted delivery of DNA and siRNA into breast cancer cells

Wan, Yu, Dai, Wei, Nevagi, Reshma J., Toth, Istvan and Moyle, Peter M. (2017). Multifunctional peptide-lipid nanocomplexes for efficient targeted delivery of DNA and siRNA into breast cancer cells. Acta Biomaterialia, 59, 257-268. doi: 10.1016/j.actbio.2017.06.032

Multifunctional peptide-lipid nanocomplexes for efficient targeted delivery of DNA and siRNA into breast cancer cells

2017

Journal Article

Development and delivery of a peptide-based vaccine against group A Streptococcus

Skwarczynski, Mariusz and Toth, Istvan (2017). Development and delivery of a peptide-based vaccine against group A Streptococcus. Infectious Diseases Hub.

Development and delivery of a peptide-based vaccine against group A Streptococcus

2017

Journal Article

Fluorinated lipids conjugated to peptide antigens do not induce immune responses against cervical cancer

Hussein, Waleed M., Mukaida, Saori, Liu, Tzu-Yu, Toth, Istvan and Skwarczynski, Mariusz (2017). Fluorinated lipids conjugated to peptide antigens do not induce immune responses against cervical cancer. Vaccination Research Open Journal, 1 (1), 39-44. doi: 10.17140/VROJ-1-107

Fluorinated lipids conjugated to peptide antigens do not induce immune responses against cervical cancer

2017

Journal Article

New gonadotropin-releasing hormone glycolipids with direct antiproliferative activity and gonadotropin-releasing potency

Varamini, Pegah, Mansfeld, Friederike M., Giddam, Ashwini Kumar, Steyn, Frederik and Toth, Istvan (2017). New gonadotropin-releasing hormone glycolipids with direct antiproliferative activity and gonadotropin-releasing potency. International Journal of Pharmaceutics, 521 (1-2), 327-336. doi: 10.1016/j.ijpharm.2017.02.054

New gonadotropin-releasing hormone glycolipids with direct antiproliferative activity and gonadotropin-releasing potency

2017

Journal Article

Synthesis, characterization and immunological evaluation of self-adjuvanting group a streptococcal vaccine candidates bearing various lipidic adjuvanting moieties

Fagan, Vincent, Hussein, Waleed M., Su, Mei, Gidda, Ashwini K., Batzloff, Michael R., Good, Michael F., Toth, Istvan and Simerska, Pavla (2017). Synthesis, characterization and immunological evaluation of self-adjuvanting group a streptococcal vaccine candidates bearing various lipidic adjuvanting moieties. ChemBioChem, 18 (6), 545-553. doi: 10.1002/cbic.201600639

Synthesis, characterization and immunological evaluation of self-adjuvanting group a streptococcal vaccine candidates bearing various lipidic adjuvanting moieties

2017

Journal Article

Intranasal delivery of nanoparticle-based vaccines

Marasini, Nirmal, Skwarczynski, Mariusz and Toth, Istvan (2017). Intranasal delivery of nanoparticle-based vaccines. Therapeutic Delivery, 8 (3), 151-167. doi: 10.4155/tde-2016-0068

Intranasal delivery of nanoparticle-based vaccines

2017

Journal Article

Comparison of fluorinated and nonfluorinated lipids in self-adjuvanting delivery systems for peptide-based vaccines

Hussein, Waleed M., Mukaida, Saori, Azmi, Fazren, Bartlett, Stacey, Olivier, Celine, Batzloff, Michael R., Good, Michael F., Skwarczynski, Mariusz and Toth, Istvan (2017). Comparison of fluorinated and nonfluorinated lipids in self-adjuvanting delivery systems for peptide-based vaccines. ACS Medicinal Chemistry Letters, 8 (2), 227-232. doi: 10.1021/acsmedchemlett.6b00453

Comparison of fluorinated and nonfluorinated lipids in self-adjuvanting delivery systems for peptide-based vaccines

2017

Journal Article

Poly-L-lysine-coated nanoparticles are ineffective in inducing mucosal immunity against group a streptococcus

Marasini, Nirmal, Giddam, Ashwini Kumar, Batzloff, Michael R. , Good, Michael F. , Skwarczynski, Mariusz and Toth, Istvan (2017). Poly-L-lysine-coated nanoparticles are ineffective in inducing mucosal immunity against group a streptococcus. Biochemical Compounds, 5 (1), 1.1-1.6. doi: 10.7243/2052-9341-5-1

Poly-L-lysine-coated nanoparticles are ineffective in inducing mucosal immunity against group a streptococcus

2017

Journal Article

Synthesis of multicomponent peptide-based vaccine candidates against group A streptococcus

Hussein, Waleed M., Xu, Jiaxin, Simerska, Pavla and Toth, Istvan (2017). Synthesis of multicomponent peptide-based vaccine candidates against group A streptococcus. Australian Journal of Chemistry, 70 (2), 184-190. doi: 10.1071/CH16501

Synthesis of multicomponent peptide-based vaccine candidates against group A streptococcus

2017

Journal Article

Recent advances in self-assembled peptides: Implications for targeted drug delivery and vaccine engineering

Eskandari, Sharareh, Guerin, Thalia, Toth, Istvan and Stephenson, Rachel J. (2017). Recent advances in self-assembled peptides: Implications for targeted drug delivery and vaccine engineering. Advanced Drug Delivery Reviews, 110, 169-187. doi: 10.1016/j.addr.2016.06.013

Recent advances in self-assembled peptides: Implications for targeted drug delivery and vaccine engineering

2017

Journal Article

The role of size in development of mucosal liposome-lipopeptide vaccine candidates against group A streptococcus

Ghaffar, Khairunnisa Abdul, Marasini, Nirmal, Giddam, Ashwini Kumar, Batzloff, Michael R., Good, Michael F., Skwarczynski, Mariusz and Toth, Istvan (2017). The role of size in development of mucosal liposome-lipopeptide vaccine candidates against group A streptococcus. Medicinal Chemistry, 13 (1), 22-27. doi: 10.2174/1573406412666160720093138

The role of size in development of mucosal liposome-lipopeptide vaccine candidates against group A streptococcus

2017

Journal Article

An overview of structural features of antibacterial glycoconjugate vaccines that influence their immunogenicity

Khatun, Farjana, Stephenson, Rachel J. and Toth, Istvan (2017). An overview of structural features of antibacterial glycoconjugate vaccines that influence their immunogenicity. Chemistry - A European Journal, 23 (18), 4233-4254. doi: 10.1002/chem.201603599

An overview of structural features of antibacterial glycoconjugate vaccines that influence their immunogenicity

2017

Journal Article

Design and evaluation of a stearylated multicomponent peptide-siRNA nanocomplex for efficient cellular siRNA delivery.

Wan, Yu, Moyle, Peter M., Gn, Pei Z. and Toth, Istvan (2017). Design and evaluation of a stearylated multicomponent peptide-siRNA nanocomplex for efficient cellular siRNA delivery.. Nanomedicine, 12 (4), 281-293. doi: 10.2217/nnm-2016-0354

Design and evaluation of a stearylated multicomponent peptide-siRNA nanocomplex for efficient cellular siRNA delivery.

2017

Journal Article

Evaluation of lipopeptides as toll-like receptor 2 ligands

Hussein, Waleed, Choi, Phil, Zhang, Cheng, Su, Mei, Sierecki, Emma, Johnston, Wayne, Fagan, Vincent, Alexandrov, Kirill, Skwarczynski, Mariusz, Gambin, Yann, Toth, Istvan and Simerska, P. (2017). Evaluation of lipopeptides as toll-like receptor 2 ligands. Current Drug Delivery, 14 (7), 935-943. doi: 10.2174/1567201813666160804114107

Evaluation of lipopeptides as toll-like receptor 2 ligands

2017

Journal Article

Polyelectrolyte coated liposome delivery systems against Group A Streptococcus (GAS) infection

Toth, Istvan (2017). Polyelectrolyte coated liposome delivery systems against Group A Streptococcus (GAS) infection. Journal of Nanomedicine & Nanotechnology, 08 (04) doi: 10.4172/2157-7439-c1-048

Polyelectrolyte coated liposome delivery systems against Group A Streptococcus (GAS) infection

2016

Journal Article

Novel platform technology for modular mucosal vaccine that protects against streptococcus

Zaman, Mehfuz, Ozberk, Victoria, Langshaw, Emma L., McPhun, Virginia, Powell, Jessica L., Phillips, Zachary N., Ho, Mei Fong, Calcutt, Ainslie, Batzloff, Michael R., Toth, Istvan, Hill, Geoffrey R., Pandey, Manisha and Good, Michael F. (2016). Novel platform technology for modular mucosal vaccine that protects against streptococcus. Scientific Reports, 6 (1) 39274, 1-11. doi: 10.1038/srep39274

Novel platform technology for modular mucosal vaccine that protects against streptococcus