2016 Journal Article Double adjuvanting strategy for peptide-based vaccines: trimethyl chitosan nanoparticles for lipopeptide deliveryMarasini, Nirmal, Giddam, Ashwini K., Khalil, Zeinab G., Hussein, Waleed M., Capon, Robert J., Batzloff, Michael R., Good, Michael F., Toth, Istvan and Skwarczynski, Mariusz (2016). Double adjuvanting strategy for peptide-based vaccines: trimethyl chitosan nanoparticles for lipopeptide delivery. Nanomedicine, 11 (24), 3223-3235. doi: 10.2217/nnm-2016-0291 |
2016 Journal Article Towards the development of synthetic antibiotics: designs inspired by natural antimicrobial peptidesAzmi, Fazren, Skwarczynski, Mariusz and Toth, Istvan (2016). Towards the development of synthetic antibiotics: designs inspired by natural antimicrobial peptides. Current Medicinal Chemistry, 23 (41), 4610-4624. doi: 10.2174/0929867323666160825162435 |
2016 Journal Article Lipid core peptide/poly(lactic-co-glycolic acid) as a highly potent intranasal vaccine delivery system against Group A streptococcusMarasini, Nirmal, Khalil, Zeinab G., Giddam, Ashwini K., Abdul Ghaffar, Khairunnisa, Hussein, Waleed M., Capon, Robert J., Batzloff, Michael R., Good, Michael F., Skwarczynski, Mariusz and Toth, Istvan (2016). Lipid core peptide/poly(lactic-co-glycolic acid) as a highly potent intranasal vaccine delivery system against Group A streptococcus. International Journal of Pharmaceutics, 513 (1-2), 410-420. doi: 10.1016/j.ijpharm.2016.09.057 |
2016 Journal Article Investigation of Bombesin peptide as a targeting ligand for the gastrin releasing peptide (GRP) receptorBegum, Anjuman Ara, Moyle, Peter M. and Toth, Istvan (2016). Investigation of Bombesin peptide as a targeting ligand for the gastrin releasing peptide (GRP) receptor. Bioorganic and Medicinal Chemistry, 24 (22), 5834-5841. doi: 10.1016/j.bmc.2016.09.039 |
2016 Journal Article A semi-synthetic whole parasite vaccine designed to protect against blood stage malariaGiddam, Ashwini Kumar, Reiman, Jennifer M., Zaman, Mehfuz, Skwarczynski, Mariusz, Toth, Istvan and Good, Michael F. (2016). A semi-synthetic whole parasite vaccine designed to protect against blood stage malaria. Acta Biomaterialia, 44, 295-303. doi: 10.1016/j.actbio.2016.08.020 |
2016 Journal Article Multiantigenic peptide-polymer conjugates as therapeutic vaccines against cervical cancerHussein, Waleed M., Liu, Tzu-Yu, Jia, Zhongfan, McMillan, Nigel A. J., Monteiro, Michael J., Toth, Istvan and Skwarczynski, Mariusz (2016). Multiantigenic peptide-polymer conjugates as therapeutic vaccines against cervical cancer. Bioorganic and Medicinal Chemistry, 24 (18), 4372-4380. doi: 10.1016/j.bmc.2016.07.036 |
2016 Journal Article Synthesis, characterization and in vitro evaluation of amphiphilic ion pairs of erythromycin and kanamycin antibiotics with liposaccharidesPignatello, Rosario, Simerska, Pavla, Leonardi, Antonio, Abdelrahim, Adel S., Petronio, Giulio Petronio, Fuochi, Virginia, Furneri, Pio Maria, Ruozi, Barbara and Toth, Istvan (2016). Synthesis, characterization and in vitro evaluation of amphiphilic ion pairs of erythromycin and kanamycin antibiotics with liposaccharides. European Journal of Medicinal Chemistry, 120, 329-337. doi: 10.1016/j.ejmech.2016.04.074 |
2016 Journal Article Linear and branched polyacrylates as a delivery platform for peptide-based vaccinesChandrudu, Saranya, Bartlett, Stacey, Khalil, Zeinab G., Jia, Zhongfan, Hussein, Waleed M., Capon, Robert J., Batzloff, Michael R., Good, Michael F., Monteiro, Michael J., Skwarczynski, Mariusz and Toth, Istvan (2016). Linear and branched polyacrylates as a delivery platform for peptide-based vaccines. Therapeutic Delivery, 7 (9), 601-609. doi: 10.4155/tde-2016-0037 |
2016 Journal Article A study on liposomal encapsulation of a lipophilic prodrug of LHRHPignatello, Rosario, Musumeci, Teresa, Graziano, Adriana C. E., Lo Furno, Debora, Varamini, Pegah, Mansfeld, Friederike M., Cardile, Venera and Toth, Istvan (2016). A study on liposomal encapsulation of a lipophilic prodrug of LHRH. Pharmaceutical Development and Technology, 21 (6), 664-671. doi: 10.3109/10837450.2015.1041045 |
2016 Journal Article Identification of host insulin binding sites on Schistosoma japonicum insulin receptorsStephenson, Rachel J., Toth, Istvan, Liang, Jiening, Mangat, Amanjot, McManus, Donald P. and You, Hong (2016). Identification of host insulin binding sites on Schistosoma japonicum insulin receptors. PLoS One, 11 (7) e0159704, e0159704. doi: 10.1371/journal.pone.0159704 |
2016 Journal Article Peptide-based multicomponent oligonucleotide delivery systems: optimisation of poly-l-lysine dendrons for plasmid DNA deliveryKamaruzaman, Khairul A., Moyle, Peter M. and Toth, Istvan (2016). Peptide-based multicomponent oligonucleotide delivery systems: optimisation of poly-l-lysine dendrons for plasmid DNA delivery. International Journal of Peptide Research and Therapeutics, 23 (1), 1-16. doi: 10.1007/s10989-016-9545-5 |
2016 Journal Article Differing efficacies of lead Group A Streptococcal vaccine candidates and full-length M protein in cutaneous and invasive disease modelsRivera-Hernandez, Tania, Pandey, Manisha, Henningham, Anna, Cole, Jason, Choudhury, Biswa, Cork, Amanda J., Gillen, Christine M., Ghaffar, Khairunnisa Abdul, West, Nicholas P., Silvestri, Guido, Good, Michael F., Moyle, Peter M., Toth, Istvan, Nizet, Victor, Batzloff, Michael R. and Walker, Mark J. (2016). Differing efficacies of lead Group A Streptococcal vaccine candidates and full-length M protein in cutaneous and invasive disease models. mBio, 7 (3) e00618-16, e00618-16.1-e00618-16.9. doi: 10.1128/mBio.00618-16 |
2016 Journal Article Short cationic lipopeptides as effective antibacterial agents: design, physicochemical properties and biological evaluationAzmi, Fazren, Elliott, Alysha G., Marasini, Nirmal, Ramu, Soumya, Ziora, Zyta, Kavanagh, Angela M., Blaskovich, Mark A. T., Cooper, Matthew A., Skwarczynski, Mariusz and Toth, Istvan (2016). Short cationic lipopeptides as effective antibacterial agents: design, physicochemical properties and biological evaluation. Bioorganic and Medicinal Chemistry, 24 (10), 2235-2241. doi: 10.1016/j.bmc.2016.03.053 |
2016 Journal Article Synthesis of glycolipid-based drug delivery systems for oral administrationLee, Wan Ling, Toth, Istvan and Simerska, Pavla (2016). Synthesis of glycolipid-based drug delivery systems for oral administration. Drug Delivery Letters, 6 (1), 38-45. doi: 10.2174/2210303106666160506155139 |
2016 Journal Article Multilayer engineered nanoliposomes as a novel tool for oral delivery of lipopeptide-based vaccines against group A StreptococcusMarasini, Nirmal, Giddam, Ashwini K., Ghaffar, Khairunnisa A., Batzloff, Michael R., Good, Michael F., Skwarczynski, Mariusz and Toth, Istvan (2016). Multilayer engineered nanoliposomes as a novel tool for oral delivery of lipopeptide-based vaccines against group A Streptococcus. Nanomedicine, 11 (10), 1223-1236. doi: 10.2217/nnm.16.36 |
2016 Journal Article Liposome-based intranasal Delivery of lipopeptide vaccine candidates against Group A StreptococcusGhaffar, Khairunnisa Abdul, Marasini, Nirmal, Giddam, Ashwini K., Batzloff, Michael, Good, Michael, Skwarczynski, Mariusz and Toth, Istvan (2016). Liposome-based intranasal Delivery of lipopeptide vaccine candidates against Group A Streptococcus. Acta Biomaterialia, 41, 161-168. doi: 10.1016/j.actbio.2016.04.012 |
2016 Journal Article Nanosized, peptide-based multicomponent DNA delivery systems: optimization of endosome escape activityWan, Yu, Moyle, Peter M., Christie, Michelle P. and Toth, Istvan (2016). Nanosized, peptide-based multicomponent DNA delivery systems: optimization of endosome escape activity. Nanomedicine, 11 (8), 907-919. doi: 10.2217/nnm.16.27 |
2016 Journal Article Peptide-based synthetic vaccinesSkwarczynski, Mariusz and Toth, Istvan (2016). Peptide-based synthetic vaccines. Chemical Science, 7 (2), 842-854. doi: 10.1039/c5sc03892h |
2016 Journal Article PrefaceToth, Istvan (2016). Preface. Current Drug Delivery, 13 (1), 3-3. doi: 10.2174/156720181301160314153150 |
2016 Journal Article Glycosylation, an effective synthetic strategy to improve the bioavailability of therapeutic peptidesMoradi, Shayli Varasteh, Hussein, Waleed M., Varamini, Pegah, Simerska, Pavla and Toth, Istvan (2016). Glycosylation, an effective synthetic strategy to improve the bioavailability of therapeutic peptides. Chemical Science, 7 (4), 2492-2500. doi: 10.1039/C5SC04392A |