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2021

Journal Article

A potent vaccine delivery system

Zhao, Guangzu, Azuar, Armira, Toth, Istvan and Skwarczynski, Mariusz (2021). A potent vaccine delivery system. Bio-protocol, 11 (7) e3973, e3973. doi: 10.21769/bioprotoc.3973

A potent vaccine delivery system

2021

Journal Article

Antibodies to neutralising epitopes synergistically block the interaction of the receptor-binding domain of SARS-CoV-2 to ACE 2

Pandey, Manisha, Ozberk, Victoria, Eskandari, Sharareh, Shalash, Ahmed O., Joyce, Michael A., Saffran, Holly A., Day, Christopher J., Lepletier, Ailin, Spillings, Belinda L., Mills, Jamie-Lee, Calcutt, Ainslie, Fan, Fan, Williams, James T., Stanisic, Danielle I., Hattingh, Laetitia, Gerrard, John, Skwarczynski, Mariusz, Mak, Johnson, Jennings, Michael P., Toth, Istvan, Tyrrell, D. Lorne and Good, Michael F. (2021). Antibodies to neutralising epitopes synergistically block the interaction of the receptor-binding domain of SARS-CoV-2 to ACE 2. Clinical and Translational Immunology, 10 (3) e1260, e1260. doi: 10.1002/cti2.1260

Antibodies to neutralising epitopes synergistically block the interaction of the receptor-binding domain of SARS-CoV-2 to ACE 2

2020

Journal Article

A dual-adjuvanting strategy for peptide-based subunit vaccines against group A Streptococcus: lipidation and polyelectrolyte complexes

Zhao, Lili, Yang, Jieru, Nahar, Ummey Jannatun, Khalil, Zeinab G., Capon, Robert J., Hussein, Waleed M., Skwarczynski, Mariusz and Toth, Istvan (2020). A dual-adjuvanting strategy for peptide-based subunit vaccines against group A Streptococcus: lipidation and polyelectrolyte complexes. Bioorganic and Medicinal Chemistry, 28 (24) 115823, 115823. doi: 10.1016/j.bmc.2020.115823

A dual-adjuvanting strategy for peptide-based subunit vaccines against group A Streptococcus: lipidation and polyelectrolyte complexes

2020

Journal Article

Erratum for: An experimental group a Streptococcus vaccine that reduces pharyngitis and tonsillitis in a nonhuman primate model (mBio, (2019) 10, 2, 10.1128/mBio.00693-19)

Rivera-Hernandez, Tania, Carnathan, Diane G., Jones, Scott, Cork, Amanda J., Davies, Mark R., Moyle, Peter M., Toth, Istvan, Batzloff, Michael R., McCarthy, James, Nizet, Victor, Goldblatt, David, Silvestri, Guido and Walker, Mark J. (2020). Erratum for: An experimental group a Streptococcus vaccine that reduces pharyngitis and tonsillitis in a nonhuman primate model (mBio, (2019) 10, 2, 10.1128/mBio.00693-19). mBio, 11 (6) e02995-20, 1-1. doi: 10.1128/mBio.02995-20

Erratum for: An experimental group a Streptococcus vaccine that reduces pharyngitis and tonsillitis in a nonhuman primate model (mBio, (2019) 10, 2, 10.1128/mBio.00693-19)

2020

Journal Article

Carbohydrate immune adjuvants in subunit vaccines

Bashiri, Sahra, Koirala, Prashamsa, Toth, Istvan and Skwarczynski, Mariusz (2020). Carbohydrate immune adjuvants in subunit vaccines. Pharmaceutics, 12 (10) 965, 965-33. doi: 10.3390/pharmaceutics12100965

Carbohydrate immune adjuvants in subunit vaccines

2020

Journal Article

Polyethylenimine: an intranasal adjuvant for liposomal peptide-based subunit vaccine against Group A Streptococcus

Dai, Charles C., Yang, Jieru, Hussein, Waleed M., Zhao, Lili, Wang, Xiumin, Khalil, Zeinab G., Capon, Robert J., Toth, Istvan and Stephenson, Rachel J. (2020). Polyethylenimine: an intranasal adjuvant for liposomal peptide-based subunit vaccine against Group A Streptococcus. ACS Infectious Diseases, 6 (9) acsinfecdis.0c00452, 2502-2512. doi: 10.1021/acsinfecdis.0c00452

Polyethylenimine: an intranasal adjuvant for liposomal peptide-based subunit vaccine against Group A Streptococcus

2020

Journal Article

Progress in the development of subunit vaccines against malaria

Skwarczynski, Mariusz, Chandrudu, Saranya, Rigau-Planella, Berta, Islam, Md. Tanjir, Cheong, Yee S., Liu, Genan, Wang, Xiumin, Toth, Istvan and Hussein, Waleed M. (2020). Progress in the development of subunit vaccines against malaria. Vaccines, 8 (3) 373, 1-19. doi: 10.3390/vaccines8030373

Progress in the development of subunit vaccines against malaria

2020

Journal Article

Opsonic activity of conservative versus variable regions of the Group A Streptococcus M protein

Dai, Chuankai, Khalil, Zeinab G., Hussein, Waleed M., Yang, Jieru, Wang, Xiumin, Zhao, Lili, Capon, Robert J., Toth, Istvan and Stephenson, Rachel J. (2020). Opsonic activity of conservative versus variable regions of the Group A Streptococcus M protein. Vaccines, 8 (2) 210, 210. doi: 10.3390/vaccines8020210

Opsonic activity of conservative versus variable regions of the Group A Streptococcus M protein

2020

Journal Article

Structure–activity analysis of cyclic multicomponent lipopeptide self-adjuvanting vaccine candidates presenting Group A Streptococcus antigens

Madge, Harrison Y. R., Sharma, Hansa, Hussein, Waleed M., Khalil, Zeinab G., Capon, Robert John, Toth, Istvan and Stephenson, Rachel (2020). Structure–activity analysis of cyclic multicomponent lipopeptide self-adjuvanting vaccine candidates presenting Group A Streptococcus antigens. Journal of Medicinal Chemistry, 63 (10) acs.jmedchem.0c00203, 5387-5397. doi: 10.1021/acs.jmedchem.0c00203

Structure–activity analysis of cyclic multicomponent lipopeptide self-adjuvanting vaccine candidates presenting Group A Streptococcus antigens

2020

Journal Article

Development of polyelectrolyte complexes for the delivery of peptide-based subunit vaccines against group A streptococcus

Zhao, Lili, Jin, Wanli, Cruz, Jazmina Gonzalez, Marasini, Nirmal, Khalil, Zeinab G., Capon, Robert J., Hussein, Waleed M., Skwarczynski, Mariusz and Toth, Istvan (2020). Development of polyelectrolyte complexes for the delivery of peptide-based subunit vaccines against group A streptococcus. Nanomaterials, 10 (5) 823, 823. doi: 10.3390/nano10050823

Development of polyelectrolyte complexes for the delivery of peptide-based subunit vaccines against group A streptococcus

2020

Journal Article

Immunology of carbohydrate-based vaccines

Khatun, Farjana, Toth, Istvan and Stephenson, Rachel J. (2020). Immunology of carbohydrate-based vaccines. Advanced Drug Delivery Reviews, 165-166, 117-126. doi: 10.1016/j.addr.2020.04.006

Immunology of carbohydrate-based vaccines

2020

Journal Article

Lipopeptide-based oral vaccine against hookworm infection

Bartlett, Stacey, Eichenberger, Ramon M., Nevagi, Reshma J., Ghaffar, Khairunnisa Abdul, Marasini, Nirmal, Dai, Yang, Loukas, Alex, Toth, Istvan and Skwarczynski, Mariusz (2020). Lipopeptide-based oral vaccine against hookworm infection. The Journal of Infectious Diseases, 221 (6), 934-942. doi: 10.1093/infdis/jiz528

Lipopeptide-based oral vaccine against hookworm infection

2020

Journal Article

Non-invasive mucosal vaccine delivery: advantages, challenges and the future

Skwarczynski, Mariusz and Toth, Istvan (2020). Non-invasive mucosal vaccine delivery: advantages, challenges and the future. Expert Opinion on Drug Delivery, 17 (4), 1-3. doi: 10.1080/17425247.2020.1731468

Non-invasive mucosal vaccine delivery: advantages, challenges and the future

2020

Journal Article

Development of natural and unnatural amino acid delivery systems against hookworm infection

Bartlett, Stacey, Skwarczynski, Mariusz, Xie, Xin, Toth, Istvan, Loukas, Alex and Eichenberger, Ramon M. (2020). Development of natural and unnatural amino acid delivery systems against hookworm infection. Precision Nanomedicine, 3 (1), 471-482. doi: 10.33218/prnano3(1).191210.1

Development of natural and unnatural amino acid delivery systems against hookworm infection

2020

Journal Article

Poly(amino acids) as a potent self-adjuvanting delivery system for peptide-based nanovaccines

Skwarczynski, Mariusz, Zhao, Guangzu, Boer, Jennifer C., Ozberk, Victoria, Azuar, Armira, Gonzalez Cruz, Jazmina, Kumar Giddam, Ashwini, Khalil, Zeinab G., Pandey, Manisha, Shibu, Mohini A., Hussein, Waleed M., Nevagi, Reshma J., Batzloff, Michael R., Wells, James W., Capon, Robert J., Plebanski, Magdalena, Good, Michael F. and Toth, Istvan (2020). Poly(amino acids) as a potent self-adjuvanting delivery system for peptide-based nanovaccines. Science Advances, 6 (5) eaax2285, eaax2285. doi: 10.1126/sciadv.aax2285

Poly(amino acids) as a potent self-adjuvanting delivery system for peptide-based nanovaccines

2020

Journal Article

Polyacrylate–peptide antigen conjugate as a single-dose oral vaccine against Group A Streptococcus

Faruck, Mohammad Omer, Zhao, Lili, Hussein, Waleed M., Khalil, Zeinab G., Capon, Robert J., Skwarczynski, Mariusz and Toth, Istvan (2020). Polyacrylate–peptide antigen conjugate as a single-dose oral vaccine against Group A Streptococcus. Vaccines, 8 (1) 23, 1-10. doi: 10.3390/vaccines8010023

Polyacrylate–peptide antigen conjugate as a single-dose oral vaccine against Group A Streptococcus

2020

Journal Article

Lipids as activators of innate immunity in peptide vaccine delivery

Bartlett, Stacey, Skwarczynski, Mariusz and Toth, Istvan (2020). Lipids as activators of innate immunity in peptide vaccine delivery. Current Medicinal Chemistry, 25 (17), 2887-2901. doi: 10.2174/0929867325666181026100849

Lipids as activators of innate immunity in peptide vaccine delivery

2020

Journal Article

Application of Fmoc-SPPS, thiol-maleimide conjugation, and copper(I)-catalyzed alkyne-azide cycloaddition "click" reaction in the synthesis of a complex peptide-based vaccine candidate against Group A Streptococcus

Dai, Chuankai, Stephenson, Rachel J., Skwarczynski, Mariusz and Toth, Istvan (2020). Application of Fmoc-SPPS, thiol-maleimide conjugation, and copper(I)-catalyzed alkyne-azide cycloaddition "click" reaction in the synthesis of a complex peptide-based vaccine candidate against Group A Streptococcus. Methods in Molecular Biology, 2103, 13-27. doi: 10.1007/978-1-0716-0227-0_2

Application of Fmoc-SPPS, thiol-maleimide conjugation, and copper(I)-catalyzed alkyne-azide cycloaddition "click" reaction in the synthesis of a complex peptide-based vaccine candidate against Group A Streptococcus

2019

Journal Article

Mannosylated liposomes formulated with whole parasite P. falciparum blood-stage antigens are highly immunogenic in mice

Ssemaganda, Aloysious, Giddam, Ashwini Kumar, Low, Leanne M., Liu, Xue Q., Ho, Mei-Fong, Zaman, Mehfuz, Hussein, Waleed M., Skwarczynski, Mariusz, Toth, Istvan, Stanisic, Danielle I. and Good, Michael F. (2019). Mannosylated liposomes formulated with whole parasite P. falciparum blood-stage antigens are highly immunogenic in mice. Vaccine, 38 (6), 1494-1504. doi: 10.1016/j.vaccine.2019.11.063

Mannosylated liposomes formulated with whole parasite P. falciparum blood-stage antigens are highly immunogenic in mice

2019

Journal Article

Polyelectrolyte-based platforms for the delivery of peptides and proteins

Zhao, Lili, Skwarczynski, Mariusz and Toth, Istvan (2019). Polyelectrolyte-based platforms for the delivery of peptides and proteins. ACS Biomaterials Science & Engineering, 5 (10) acsbiomaterials.9b01135, 4937-4950. doi: 10.1021/acsbiomaterials.9b01135

Polyelectrolyte-based platforms for the delivery of peptides and proteins