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2014

Journal Article

Self-adjuvanting vaccine against group A streptococcus: application of fibrillized peptide and immunostimulatory lipid as adjuvant

Azmi, Fazren, Ahmad Fuaad, Abdullah Al Hadi, Giddam, Ashwini Kumar, Batzloff, Michael R., Good, Michael F., Skwarczynski, Mariusz and Toth, Istvan (2014). Self-adjuvanting vaccine against group A streptococcus: application of fibrillized peptide and immunostimulatory lipid as adjuvant. Bioorganic and Medicinal Chemistry, 22 (22), 6401-6408. doi: 10.1016/j.bmc.2014.09.042

Self-adjuvanting vaccine against group A streptococcus: application of fibrillized peptide and immunostimulatory lipid as adjuvant

2014

Journal Article

Stability, Permeability and Growth-Inhibitory Properties of Gonadotropin-Releasing Hormone Liposaccharides

Goodwin, Daryn, Varamini, Pegah, Simerska, Pavla and Toth, Istvan (2014). Stability, Permeability and Growth-Inhibitory Properties of Gonadotropin-Releasing Hormone Liposaccharides. Pharmaceutical Research, 32 (5), 1570-1584. doi: 10.1007/s11095-014-1558-1

Stability, Permeability and Growth-Inhibitory Properties of Gonadotropin-Releasing Hormone Liposaccharides

2014

Journal Article

Targeting the mannose receptor with mannosylated subunit vaccines

Sedaghat, B., Stephenson, R. and Toth, I. (2014). Targeting the mannose receptor with mannosylated subunit vaccines. Current Medicinal Chemistry, 21 (30), 3405-3418. doi: 10.2174/0929867321666140826115552

Targeting the mannose receptor with mannosylated subunit vaccines

2014

Journal Article

Active immunisation of mice with GnRH lipopeptide vaccine candidates: importance of T helper or multi-dimer GnRH epitope

Goodwin, Daryn, Simerska, Pavla, Chang, Cheng-Hung, Mansfeld, Friederike M., Varamini, Pegah, D'Occhio, Michael J. and Toth, Istvan (2014). Active immunisation of mice with GnRH lipopeptide vaccine candidates: importance of T helper or multi-dimer GnRH epitope. Bioorganic and Medicinal Chemistry, 22 (17), 4848-4854. doi: 10.1016/j.bmc.2014.06.052

Active immunisation of mice with GnRH lipopeptide vaccine candidates: importance of T helper or multi-dimer GnRH epitope

2014

Journal Article

Schistosome vaccine adjuvants in preclinical and clinical research

Stephenson, Rachel, You, Hong, McManus, Donald P. and Toth, Istvan (2014). Schistosome vaccine adjuvants in preclinical and clinical research. Vaccines, 2 (3), 654-685. doi: 10.3390/vaccines2030654

Schistosome vaccine adjuvants in preclinical and clinical research

2014

Journal Article

The transport and efflux of glycosylated luteinising hormone-releasing hormone analogues in Caco-2 cell model: contributions of glucose transporters and efflux systems

Moradi, Shayli Varasteh, Varamini, Pegah and Toth, Istvan (2014). The transport and efflux of glycosylated luteinising hormone-releasing hormone analogues in Caco-2 cell model: contributions of glucose transporters and efflux systems. Journal of Pharmaceutical Sciences, 103 (10), 3217-3224. doi: 10.1002/jps.24120

The transport and efflux of glycosylated luteinising hormone-releasing hormone analogues in Caco-2 cell model: contributions of glucose transporters and efflux systems

2014

Journal Article

Oral delivery of nanoparticle-based vaccines

Marasini, Nirmal, Skwarczynski, Mariusz and Toth, Istvan (2014). Oral delivery of nanoparticle-based vaccines. Expert Review of Vaccines, Early Online (11), 1361-1376. doi: 10.1586/14760584.2014.936852

Oral delivery of nanoparticle-based vaccines

2014

Journal Article

Effect of lipidated gonadotropin-releasing hormone peptides on receptor mediated binding and uptake into prostate cancer cells in vitro

Stephenson, Rachel, Varamini, Pegah, Butcher, Neville, Minchin, Rodney and Toth, Istvan (2014). Effect of lipidated gonadotropin-releasing hormone peptides on receptor mediated binding and uptake into prostate cancer cells in vitro. Nanomedicine: Nanotechnology, Biology and Medicine, 10 (8), 1799-1808. doi: 10.1016/j.nano.2014.06.015

Effect of lipidated gonadotropin-releasing hormone peptides on receptor mediated binding and uptake into prostate cancer cells in vitro

2014

Journal Article

Convergent synthetic methodology for the construction of self-adjuvanting lipopeptide vaccines using a novel carbohydrate scaffold

Fagan, Vincent, Toth, Istvan and Simerska, Pavla (2014). Convergent synthetic methodology for the construction of self-adjuvanting lipopeptide vaccines using a novel carbohydrate scaffold. Beilstein Journal of Organic Chemistry, 10 (1), 1741-1748. doi: 10.3762/bjoc.10.181

Convergent synthetic methodology for the construction of self-adjuvanting lipopeptide vaccines using a novel carbohydrate scaffold

2014

Journal Article

Site-specific incorporation of three toll-like receptor 2 targeting adjuvants into semisynthetic, molecularly defined nanoparticles: application to group A streptococcal vaccines

Moyle, Peter M., Dai, Wei, Zhang, Yingkai, Batzloff, Michael R., Good, Michael F. and Toth, Istvan (2014). Site-specific incorporation of three toll-like receptor 2 targeting adjuvants into semisynthetic, molecularly defined nanoparticles: application to group A streptococcal vaccines. Bioconjugate Chemistry, 25 (5), 965-978. doi: 10.1021/bc500108b

Site-specific incorporation of three toll-like receptor 2 targeting adjuvants into semisynthetic, molecularly defined nanoparticles: application to group A streptococcal vaccines

2014

Journal Article

Calorimetry and Langmuir-Blodgett studies on the interaction of a lipophilic prodrug of LHRH with biomembrane models

Sarpietro, Maria G., Accolla, Maria L., Santoro, Nancy, Mansfeld, Friederike M., Pignatello, Rosario, Toth, Istvan and Castelli, Francesco (2014). Calorimetry and Langmuir-Blodgett studies on the interaction of a lipophilic prodrug of LHRH with biomembrane models. Journal of Colloid and Interface Science, 421, 122-131. doi: 10.1016/j.jcis.2014.01.040

Calorimetry and Langmuir-Blodgett studies on the interaction of a lipophilic prodrug of LHRH with biomembrane models

2014

Journal Article

Use of virulence determinants and seropathotypes to distinguish high- and low-risk Escherichia coli O157 and non-O157 isolates from Europe

Anjum, M. F., Jones, E., Morrison, V., Tozzoli, R., Morabito, S., Toth, I., Nagy, B., Smith, G., Aspan, A., Nielsen, E. M., Fach, P., Herrera-León, S., Woodward, M. J. and La Ragione, R. M. (2014). Use of virulence determinants and seropathotypes to distinguish high- and low-risk Escherichia coli O157 and non-O157 isolates from Europe. Epidemiology and Infection, 142 (5), 1019-1028. doi: 10.1017/S0950268813001635

Use of virulence determinants and seropathotypes to distinguish high- and low-risk Escherichia coli O157 and non-O157 isolates from Europe

2014

Journal Article

Liposomes as Nanovaccine Delivery Systems

Ghaffar, Khairunnisa Abdul, Giddam, Ashwini Kumar, Zaman, Mehfuz, Skwarczynski, Mariusz and Toth, Istvan (2014). Liposomes as Nanovaccine Delivery Systems. Current Topics in Medicinal Chemistry, 14 (9), 1194-1208. doi: 10.2174/1568026614666140329232757

Liposomes as Nanovaccine Delivery Systems

2014

Journal Article

A drug delivery strategy: binding enkephalin to asialoglycoprotein receptor by enzymatic galactosylation

Christie, Michelle P., Simerská, Pavla, Jen, Freda E.-C., Hussein, Waleed M., Rawi, Mohamad F. M., Hartley-Tassell, Lauren E., Day, Christopher J., Jennings, Michael P. and Toth, Istvan (2014). A drug delivery strategy: binding enkephalin to asialoglycoprotein receptor by enzymatic galactosylation. PLoS One, 9 (4) e95024, e95024.1-e95024.10. doi: 10.1371/journal.pone.0095024

A drug delivery strategy: binding enkephalin to asialoglycoprotein receptor by enzymatic galactosylation

2014

Journal Article

Toll-like receptor agonists: a patent review (2011 - 2013)

Hussein, Waleed M., Liu, Tzu-Yu, Skwarczynski, Mariusz and Toth, Istvan (2014). Toll-like receptor agonists: a patent review (2011 - 2013). Expert Opinion on Therapeutic Patents, 24 (4), 453-470. doi: 10.1517/13543776.2014.880691

Toll-like receptor agonists: a patent review (2011 - 2013)

2014

Journal Article

Recent progress in adjuvant discovery for peptide-based subunit vaccines

Azmi, Fazren, Fuaad, Abdullah Al Hadi Ahmad, Skwarczynski, Mariusz and Toth, Istvan (2014). Recent progress in adjuvant discovery for peptide-based subunit vaccines. Human Vaccines and Immunotherapeutics, 10 (3), 778-796. doi: 10.4161/hv.27332

Recent progress in adjuvant discovery for peptide-based subunit vaccines

2014

Journal Article

Delivery of a lactose derivative of endomorphin 1 to the brain via the olfactory epithelial pathway

Cros, Cécile D., Toth, Istvan and Blanchfield, Joanne T. (2014). Delivery of a lactose derivative of endomorphin 1 to the brain via the olfactory epithelial pathway. Bioorganic and Medicinal Chemistry Letters, 24 (5), 1373-1375. doi: 10.1016/j.bmcl.2014.01.041

Delivery of a lactose derivative of endomorphin 1 to the brain via the olfactory epithelial pathway

2014

Journal Article

Ovalbumin lipid core peptide vaccines and their CD4+ and CD8+ T cell responses

Simerska, Pavla, Suksamran, Tittaya, Ziora, Zyta Maria, Rivera, Fabian de Labastida, Engwerda, Christian and Toth, Istvan (2014). Ovalbumin lipid core peptide vaccines and their CD4+ and CD8+ T cell responses. Vaccine, 32 (37), 4743-4750. doi: 10.1016/j.vaccine.2014.06.049

Ovalbumin lipid core peptide vaccines and their CD4+ and CD8+ T cell responses

2014

Journal Article

Polymer–peptide hybrids as a highly immunogenic single-dose nanovaccine

Ahmad Fuaad, Abdullah A. H., Jia, Zhongfan, Hartas, Jon, Ziora, Zyta M., Lin, I-Chun, Moyle, Peter M., Batzloff, Michael R., Good, Michael F., Monteiro, Michael J., Skwarczynski, Mariusz and Toth, Istvan (2014). Polymer–peptide hybrids as a highly immunogenic single-dose nanovaccine. Nanomedicine, 9 (1), 35-43. doi: 10.2217/NNM.13.7

Polymer–peptide hybrids as a highly immunogenic single-dose nanovaccine

2014

Journal Article

Lipid core peptide targeting the cathepsin D hemoglobinase of Schistosoma mansoni as a component of a schistosomiasis vaccine

Dougall, Annette M., Skwarczynski, Mariusz, Khoshnejad, Makan, Chandrudu, Saranya, Daly, Norelle L., Toth, Istvan and Loukas, Alex (2014). Lipid core peptide targeting the cathepsin D hemoglobinase of Schistosoma mansoni as a component of a schistosomiasis vaccine. Human Vaccines and Immunotherapeutics, 10 (2), 399-409. doi: 10.4161/hv.27057

Lipid core peptide targeting the cathepsin D hemoglobinase of Schistosoma mansoni as a component of a schistosomiasis vaccine