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2016

Journal Article

The toll-like receptor 3 pathway in homeostasis, responses to injury and wound repair

Ramnath, Divya, Powell, Elizabeth E., Scholz, Glen M. and Sweet, Matthew J. (2016). The toll-like receptor 3 pathway in homeostasis, responses to injury and wound repair. Seminars in Cell and Developmental Biology, 61, 22-30. doi: 10.1016/j.semcdb.2016.08.014

The toll-like receptor 3 pathway in homeostasis, responses to injury and wound repair

2016

Conference Publication

A new Toll-like receptor adaptor protein that provides specificity to inflammatory cytokine production from macrophages

Luo, L., Bokil, N., Lansdaal, N., Wall, A., Marceline, F., Guo, Z., Alexandrov, K., Ross, I, Hibbs, M., Stow, J. and Sweet, M. (2016). A new Toll-like receptor adaptor protein that provides specificity to inflammatory cytokine production from macrophages. International Congress of Immunology (ICI), Melbourne Australia, 21-26 August 2016. HOBOKEN: Wiley-Blackwell.

A new Toll-like receptor adaptor protein that provides specificity to inflammatory cytokine production from macrophages

2016

Book Chapter

Co-transcriptomic analysis by RNA sequencing to simultaneously measure regulated gene expression in host and bacterial pathogen

Ravasi, Timothy, Mavromatis, Charalampos (Harris), Bokil, Nilesh J., Schembri, Mark A. and Sweet, Matthew J. (2016). Co-transcriptomic analysis by RNA sequencing to simultaneously measure regulated gene expression in host and bacterial pathogen. Toll-like receptors: practice and methods. (pp. 145-158) edited by Claire E. McCoy. Heidelberg, Germany: Springer. doi: 10.1007/978-1-4939-3335-8_10

Co-transcriptomic analysis by RNA sequencing to simultaneously measure regulated gene expression in host and bacterial pathogen

2015

Journal Article

The role of H4 flagella in Escherichia coli ST131 virulence

Kakkanat, Asha, Totsika, Makrina, Schaale, Kolja, Duell, Benjamin L., Lo, Alvin W., Phan, Minh-Duy, Moriel, Danilo G., Beatson, Scott A., Sweet, Matthew J., Ulett, Glen C. and Schembri, Mark A. (2015). The role of H4 flagella in Escherichia coli ST131 virulence. Scientific Reports, 5 (16149) 16149, 1-14. doi: 10.1038/srep16149

The role of H4 flagella in Escherichia coli ST131 virulence

2015

Journal Article

Inhibition of histone deacetylases permits lipopolysaccharide-mediated secretion of bioactive IL-1b via a caspase-1-independent mechanism

Stammler, Dominik, Eigenbrod, Tatjana, Menz, Sarah, Frick, Julia S., Sweet, Matthew J., Shakespear, Melanie R., Jantsch, Jonathan, Siegert, Isabel, Wolfle, Sabine, Langer, Julian D., Oehme, Ina, Schaefer, Liliana, Fischer, Andre, Knievel, Judith, Heeg, Klaus, Dalpke, Alexander H. and Bode, Konrad A. (2015). Inhibition of histone deacetylases permits lipopolysaccharide-mediated secretion of bioactive IL-1b via a caspase-1-independent mechanism. Journal of Immunology, 195 (11), 5421-5431. doi: 10.4049/jimmunol.1501195

Inhibition of histone deacetylases permits lipopolysaccharide-mediated secretion of bioactive IL-1b via a caspase-1-independent mechanism

2015

Journal Article

Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury

Irvine, Katharine M., Clouston, Andrew D., Gadd, Victoria L., Miller, Gregory C., Wong, Weng-Yew, Melino, Michelle, Maradana, Muralidhara Rao, MacDonald, Kelli, Lang, Richard A., Sweet, Matthew J., Blumenthal, Antje and Powell, Elizabeth E. (2015). Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury. Fibrogenesis and Tissue Repair, 8 (19) 19, 19. doi: 10.1186/s13069-015-0036-7

Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury

2015

Journal Article

Uropathogenic Escherichia coli engages CD14-dependent signaling to enable bladder macrophage-dependent control of acute urinary tract infection

Carey, Alison J., Sullivan, Matthew J., Duell, Benjamin L., Crossman, David K., Chattopadhyay, Debasish., Brooks, Andrew J., Tan, Chee K., Crowley, Michael., Sweet, Matthew J., Schembri, Mark A. and Ulett, Glen C. (2015). Uropathogenic Escherichia coli engages CD14-dependent signaling to enable bladder macrophage-dependent control of acute urinary tract infection. The Journal of infectious diseases, 213 (4), 659-668. doi: 10.1093/infdis/jiv424

Uropathogenic Escherichia coli engages CD14-dependent signaling to enable bladder macrophage-dependent control of acute urinary tract infection

2015

Journal Article

TLR3 drives IRF6-dependent IL-23p19 expression and p19/EBI3 heterodimer formation in keratinocytes

Ramnath, Divya, Tunny, Kathryn, Hohenhaus, Daniel M., Pitts, Claire M., Bergot, Anne-Sophie, Hogarth, P. Mark, Hamilton, John A., Kapetanovic, Ronan, Sturm, Richard A., Scholz, Glen M. and Sweet, Matthew J. (2015). TLR3 drives IRF6-dependent IL-23p19 expression and p19/EBI3 heterodimer formation in keratinocytes. Immunology and Cell Biology, 93 (9), 771-779. doi: 10.1038/icb.2015.77

TLR3 drives IRF6-dependent IL-23p19 expression and p19/EBI3 heterodimer formation in keratinocytes

2015

Journal Article

HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombi

Ahrens, Ingo, Chen, Yung-Chih, Topcic, Danijal, Bode, Michael, Haenel, David, Hagemeyer, Christoph E., Seeba, Hannah, Duerschmied, Daniel, Bassler, Nicole, Jandeleit-Dahm, Karin A., Sweet, Matthew J., Agrotis, Alex, Bobik, Alex and Peter, Karlheinz (2015). HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombi. Thrombosis and Haemostasis, 114 (5), 994-1003. doi: 10.1160/TH14-12-1073

HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombi

2015

Journal Article

Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice.

Sester, David P., Sagulenko, Vitaliya, Thygesen, Sara J., Cridland, Jasmyn A., Loi, Yen Siew, Cridland, Simon O., Masters, Seth L., Genske, Ulrich, Hornung, Veit, Andoniou, Christopher E., Sweet, Matthew J., Degli-Esposti, Mariapia A., Schroder, Kate and Stacey, Katryn J. (2015). Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice.. Journal of Immunology, 195 (3), 1233-1241. doi: 10.4049/jimmunol.1402859

Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice.

2015

Journal Article

Innate immune perturbations, accumulating DAMPs and inflammasome dysregulation: a ticking time bomb in ageing

Kapetanovic, Ronan, Bokil, Nilesh J. and Sweet, Matthew J. (2015). Innate immune perturbations, accumulating DAMPs and inflammasome dysregulation: a ticking time bomb in ageing. Ageing Research Reviews, 24 (Pt A), 40-53. doi: 10.1016/j.arr.2015.02.005

Innate immune perturbations, accumulating DAMPs and inflammasome dysregulation: a ticking time bomb in ageing

2015

Journal Article

The co-transcriptome of uropathogenic Escherichia coli-infected mouse macrophages reveals new insights into host–pathogen interactions

Mavromatis, Charalampos (Harris), Bokil, Nilesh J., Totsika, Makrina, Kakkanat, Asha, Schaale, Kolja, Cannistraci, Carlo V., Ryu, Taewoo, Beatson, Scott A., Ulett, Glen C., Schembri, Mark A., Sweet, Matthew J. and Ravasi, Timothy (2015). The co-transcriptome of uropathogenic Escherichia coli-infected mouse macrophages reveals new insights into host–pathogen interactions. Cellular Microbiology, 17 (5), 730-746. doi: 10.1111/cmi.12397

The co-transcriptome of uropathogenic Escherichia coli-infected mouse macrophages reveals new insights into host–pathogen interactions

2014

Journal Article

Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration

Irvine, Katharine M., Skoien, Richard, Bokil, Nilesh J., Melino, Michelle, Thomas, Gethin P., Loo, Dorothy, Gabrielli, Brian, Hill, Michelle M., Sweet, Matthew J., Clouston, Andrew D. and Powell, Elizabeth E. (2014). Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration. World Journal of Gastroenterology, 20 (47), 17851-17862. doi: 10.3748/wjg.v20.i47.17851

Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration

2014

Journal Article

Receptor-interacting protein kinase 4 and interferon regulatory factor 6 function as a signaling axis to regulate keratinocyte differentiation

Kwa, Mei Qi, Huynh, Jennifer, Aw, Jiamin, Zhang, Lianyi, Nguyen, Thao, Reynolds, Eric C., Sweet, Matthew J., Hamilton, John A. and Scholz, Glen M. (2014). Receptor-interacting protein kinase 4 and interferon regulatory factor 6 function as a signaling axis to regulate keratinocyte differentiation. Journal of Biological Chemistry, 289 (45), 31077-31087. doi: 10.1074/jbc.M114.589382

Receptor-interacting protein kinase 4 and interferon regulatory factor 6 function as a signaling axis to regulate keratinocyte differentiation

2014

Journal Article

The Neutrophil NLRC4 Inflammasome Selectively Promotes IL-1β Maturation without Pyroptosis during Acute Salmonella Challenge

Chen, Kaiwen W., Groß, Christina J., Vasquez Sotomayor, Flor, Stacey, Katryn J., Tschopp, Jurg, Sweet, Matthew J. and Schroder, Kate (2014). The Neutrophil NLRC4 Inflammasome Selectively Promotes IL-1β Maturation without Pyroptosis during Acute Salmonella Challenge. Cell Reports, 8 (2), 570-582. doi: 10.1016/j.celrep.2014.06.028

The Neutrophil NLRC4 Inflammasome Selectively Promotes IL-1β Maturation without Pyroptosis during Acute Salmonella Challenge

2014

Journal Article

Interferon regulatory factor 6 differentially regulates toll-like receptor 2-dependent chemokine gene expression in epithelial cells

Kwa, Mei Qi, Nguyen, Thao, Huynh, Jennifer, Ramnath, Divya, De Nardo, Dominic, Lam, Pei Yeng, Reynolds, Eric C., Hamilton, John A., Sweet, Matthew J. and Scholz, Glen M. (2014). Interferon regulatory factor 6 differentially regulates toll-like receptor 2-dependent chemokine gene expression in epithelial cells. Journal of Biological Chemistry, 289 (28), 19758-19768. doi: 10.1074/jbc.M114.584540

Interferon regulatory factor 6 differentially regulates toll-like receptor 2-dependent chemokine gene expression in epithelial cells

2014

Journal Article

Towards selective lysophospholipid GPCR modulators

Archbold, Julia K., Martin, Jennifer L. and Sweet, Matthew J. (2014). Towards selective lysophospholipid GPCR modulators. Trends in Pharmacological Sciences, 35 (5), 219-226. doi: 10.1016/j.tips.2014.03.004

Towards selective lysophospholipid GPCR modulators

2014

Journal Article

Tumor cell-expressed SerpinB2 is present on microparticles and inhibits metastasis

Schroder, Wayne A., Major, Lee D., Le, Thuy T., Gardner, Joy, Sweet, Matthew J., Janciauskiene, Sabina and Suhrbier, Andreas (2014). Tumor cell-expressed SerpinB2 is present on microparticles and inhibits metastasis. Cancer Medicine, 3 (3), 500-513. doi: 10.1002/cam4.229

Tumor cell-expressed SerpinB2 is present on microparticles and inhibits metastasis

2014

Journal Article

Protective role for toll-like receptor-9 in the development of atherosclerosis in apolipoprotein e-deficient mice

Koulis, Christine, Chen, Yung-Chih, Hausding, Christian, Ahrens, Ingo, Kyaw, Tin Soe, Tay, Christopher, Allen, Terri, Jandeleit-Dahm, Karin, Sweet, Matthew J., Akira, Shizuo, Bobik, Alexander, Peter, Karlheinz and Agrotis, Alex (2014). Protective role for toll-like receptor-9 in the development of atherosclerosis in apolipoprotein e-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology, 34 (3), 516-525. doi: 10.1161/ATVBAHA.113.302407

Protective role for toll-like receptor-9 in the development of atherosclerosis in apolipoprotein e-deficient mice

2014

Book Chapter

Evolutionary divergence in human versus mouse innate immune genes

Kapetanovic, Ronan, Ariffin, Juliana K. and Sweet, Matthew J. (2014). Evolutionary divergence in human versus mouse innate immune genes. Evolutionary biology: genome evolution, speciation, coevolution and origin of life. (pp. 115-155) edited by Pierre Pontarotti. Heidelberg, Germany: Springer. doi: 10.1007/978-3-319-07623-2_6

Evolutionary divergence in human versus mouse innate immune genes