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2025 Journal Article Enhancement of anti-sarcoma immunity by NK cells engineered with mRNA for expression of a EphA2-targeted CARLam, Pui Yeng, Omer, Natacha, Wong, Josh K. M., Tu, Cui, Alim, Louisa, Rossi, Gustavo R., Victorova, Maria, Tompkins, Hannah, Lin, Cheng-Yu, Mehdi, Ahmed M., Choo, Amos, Elliott, Melissa R., Coleborn, Elaina, Sun, Jane, Mercer, Timothy, Vittorio, Orazio, Dobson, Lachlan J., Mclellan, Alexander D., Brooks, Andrew, Tuong, Zewen Kelvin, Cheetham, Seth W., Nicholls, Wayne and Souza-Fonseca-Guimaraes, Fernando (2025). Enhancement of anti-sarcoma immunity by NK cells engineered with mRNA for expression of a EphA2-targeted CAR. Clinical and Translational Medicine, 15 (1) e70140, 1-21. doi: 10.1002/ctm2.70140 |
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2025 Journal Article Engineered iPSC‐derived natural killer cells: recent innovations in translational innate anti‐cancer immunotherapySun, Jane, Elliott, Melissa and Souza‐Fonseca‐Guimaraes, Fernando (2025). Engineered iPSC‐derived natural killer cells: recent innovations in translational innate anti‐cancer immunotherapy. Clinical and Translational Immunology, 14 (7) e70045, 1-15. doi: 10.1002/cti2.70045 |
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2025 Conference Publication Probing extracellular vesicle interactions with lipoproteins in healthy and disease contextsGhebosu, Raluca, Pendiuk Goncalves, Jenifer, Fitri, Nur Indah, Iannotta, Dalila, Sharifpour, Mohammad Farouq, Coleborn, Elaina, Loukas, Alex, Souza-Fonseca-Guimaraes, Fernando and Wolfram, Joy (2025). Probing extracellular vesicle interactions with lipoproteins in healthy and disease contexts. International Society for Extracellular Vesicles Annual Meeting, Vienna, Austria, 23-27 April 2025. |
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2024 Conference Publication Unravelling immune mechanisms and precision therapies for cancers and infectious diseasesSouza-Fonseca-Guimaraes, Fernando (2024). Unravelling immune mechanisms and precision therapies for cancers and infectious diseases. Multi-Omics 2024, Brisbane, QLD, Australia, 1-3 December 2024. |
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2024 Conference Publication Advances in NK cell biologySouza-Fonseca-Guimaraes, Fernando (2024). Advances in NK cell biology. Australasian Society of Immunology - Annual Meeting, Sydney, NSW, Australia, 26-29 November 2024. |
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2024 Conference Publication Towards immunotherapy development for bacterial infectionSouza-Fonseca-Guimaraes, Fernando (2024). Towards immunotherapy development for bacterial infection. Australian Infectious Diseases Research Centre - 2024 Symposium, Brisbane, QLD, Australia, 21 November 2024. |
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2024 Journal Article Dichotomous outcomes of TNFR1 and TNFR2 signaling in NK cell-mediated immune responses during inflammationMcCulloch, Timothy R., Rossi, Gustavo R., Alim, Louisa, Lam, Pui Yeng, Wong, Joshua K. M., Coleborn, Elaina, Kumari, Snehlata, Keane, Colm, Kueh, Andrew J., Herold, Marco J., Wilhelm, Christoph, Knolle, Percy A., Kane, Lawrence, Wells, Timothy J. and Souza-Fonseca-Guimaraes, Fernando (2024). Dichotomous outcomes of TNFR1 and TNFR2 signaling in NK cell-mediated immune responses during inflammation. Nature Communications, 15 (1) 9871, 1-16. doi: 10.1038/s41467-024-54232-y |
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2024 Conference Publication Natural killer cell-based therapy for sarcomaSouza-Fonseca-Guimaraes, Fernando (2024). Natural killer cell-based therapy for sarcoma. 2024 Sarcoma Symposium, Sydney, NSW, Australia, 8 Nov 2024. |
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2024 Conference Publication Unlocking the anti-cancer immunity: advancements in immunotherapy against sarcomaSouza-Fonseca-Guimaraes, Fernando (2024). Unlocking the anti-cancer immunity: advancements in immunotherapy against sarcoma. 22nd International Society of Limb Salvage General Meeting, Brisbane, QLD, Australia, 11-13 October 2024. |
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2024 Journal Article A scalable, spin‐free approach to generate enhanced induced pluripotent stem cell–derived natural killer cells for cancer immunotherapyRossi, Gustavo R., Sun, Jane, Lin, Cheng‐Yu, Wong, Joshua K.M., Alim, Louisa, Lam, Pui Yeng, Khosrotehrani, Kiarash, Wolvetang, Ernst, Cheetham, Seth W., Derrick, Emily B., Amoako, Akwasi, Lehner, Christoph, Brooks, Andrew J., Beavis, Paul A. and Souza‐Fonseca‐Guimaraes, Fernando (2024). A scalable, spin‐free approach to generate enhanced induced pluripotent stem cell–derived natural killer cells for cancer immunotherapy. Immunology & Cell Biology, 102 (10), 1-11. doi: 10.1111/imcb.12820 |
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2024 Journal Article The current molecular and cellular landscape of chronic obstructive pulmonary disease (COPD): a review of therapies and efforts towards personalized treatmentFarrell, Luke A., O’Rourke, Matthew B., Padula, Matthew P., Souza-Fonseca-Guimaraes, Fernando, Caramori, Gaetano, Wark, Peter A. B., Dharmage, Shymali C. and Hansbro, Phillip M. (2024). The current molecular and cellular landscape of chronic obstructive pulmonary disease (COPD): a review of therapies and efforts towards personalized treatment. Proteomes, 12 (3) 23, 1-31. doi: 10.3390/proteomes12030023 |
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2024 Other Outputs Potential new treatment pathway for bladder cancerGuimaraes, Fernando S. F. (2024, 08 21). Potential new treatment pathway for bladder cancer UQ News |
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2024 Conference Publication Trastuzumab-induced cardiotoxicity involves antibody dependent cell cytotoxicity (ADCC)Griffiths, L., Ho, U., Burt, K., Watson, S., Patel, K., Bradford, J., Tan, C., Bhavsar, C., Palpant, N., Souza-Fonseca-Guimaraes, F., Wu, S., Reichelt, M. and Thomas, W. (2024). Trastuzumab-induced cardiotoxicity involves antibody dependent cell cytotoxicity (ADCC). 72nd Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, Perth, WA Australia, 1-4 August 2024. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2024.06.397 |
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2024 Journal Article Highlight of 2023: Unlocking the therapeutic potential of natural killer cells—advances in adaptive functions, cellular engineering and immunotherapyLam, Pui Yeng and Souza‐Fonseca‐Guimaraes, Fernando (2024). Highlight of 2023: Unlocking the therapeutic potential of natural killer cells—advances in adaptive functions, cellular engineering and immunotherapy. Immunology and Cell Biology, 102 (6), 444-447. doi: 10.1111/imcb.12769 |
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2024 Journal Article The immune checkpoint TIGIT is upregulated on T cells during bacterial infection and is a potential target for immunotherapyMcCulloch, Timothy R., Rossi, Gustavo R., Miranda‐Hernandez, Socorro, Valencia‐Hernandez, Ana Maria, Alim, Louisa, Belle, Clemence J., Krause, Andrew, Zacchi, Lucia F., Lam, Pui Yeng, Nakamura, Kyohei, Kupz, Andreas, Wells, Timothy J. and Souza‐Fonseca‐Guimaraes, Fernando (2024). The immune checkpoint TIGIT is upregulated on T cells during bacterial infection and is a potential target for immunotherapy. Immunology and Cell Biology, 102 (8), 721-733. doi: 10.1111/imcb.12794 |
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2024 Journal Article TGF-β signalling limits effector function capacity of NK cell anti-tumour immunity in human bladder cancerWong, Joshua K. M., McCulloch, Timothy R., Alim, Louisa, Omer, Natacha, Mehdi, Ahmed M., Tuong, Zewen Kelvin, Bonfim-Melo, Alexis, Chung, Eric, Nicol, Alice, Simpson, Fiona, Rhee, Handoo, Rossi, Gustavo Rodrigues and Souza-Fonseca-Guimaraes, Fernando (2024). TGF-β signalling limits effector function capacity of NK cell anti-tumour immunity in human bladder cancer. EBioMedicine, 104 105176, 1-15. doi: 10.1016/j.ebiom.2024.105176 |
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2024 Conference Publication Natural Killer cell-based cancer immunotherapy for rhabdomyosarcomaRossi, Gustavo Rodrigues, Lam, Pui Yeng, Omer, Natacha, Tu, Cui and Souza-Fonseca-Guimaraes, Fernando (2024). Natural Killer cell-based cancer immunotherapy for rhabdomyosarcoma. Annual Meeting of the American Association of Immunologists (IMMUNOLOGY), Chicago, IL, United States, 3-7 May 2024. Cary, NC, United States: Oxford University Press. doi: 10.4049/jimmunol.212.supp.1399.5214 |
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2024 Conference Publication TGF-β signaling limits effector function capacity of NK cell anti-cancer immunity in human bladder cancerWong, Joshua, Rossi, Gustavo Rodrigues and Guimaraes, Fernando (2024). TGF-β signaling limits effector function capacity of NK cell anti-cancer immunity in human bladder cancer. Annual Meeting of the American Association of Immunologists (IMMUNOLOGY), Chicago, IL, United States, 3-7 May 2024. Cary, NC, United States: Oxford University Press. doi: 10.4049/jimmunol.212.supp.1431.4524 |
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2024 Conference Publication Spatial profiling of pediatric rhabdomyosarcoma to elucidate their immunosuppressive tumor microenvironmentTu, Cui, Tan, Chin Wee, Liu, Ning, Kulasinghe, Arutha and Souza-Fonseca-Guimaraes, Fernando (2024). Spatial profiling of pediatric rhabdomyosarcoma to elucidate their immunosuppressive tumor microenvironment. American Association for Cancer Research Annual Meeting 2024, San Diego, CA United States, 5-10 April 2024. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2024-73 |
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2024 Journal Article In situ single-cell profiling sheds light on IFI27 localisation during SARS-CoV-2 infectionTan, Chin Wee, Chen, Jinjin, Liu, Ning, Bhuva, Dharmesh D., Blick, Tony, Monkman, James, Cooper, Caroline, Kharbanda, Malvika, Feher, Kristen, Phipson, Belinda, Killingbeck, Emily E., Pan, Liuliu, Kim, Youngmi, Liang, Yan, Nam, Andy, Leon, Michael, Souza-Fonseca-Guimaraes, Paulo, Nagashima, Seigo, Camargo Martins, Ana Paula, Machado-Souza, Cleber, de Noronha, Lucia, Tang, Benjamin, Short, Kirsty, Fraser, John, Belz, Gabrielle T., Souza-Fonseca-Guimaraes, Fernando, Kulasinghe, Arutha and Davis, Melissa J. (2024). In situ single-cell profiling sheds light on IFI27 localisation during SARS-CoV-2 infection. eBioMedicine, 101 105016, 1-4. doi: 10.1016/j.ebiom.2024.105016 |