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2025

Journal Article

Enhancement of anti-sarcoma immunity by NK cells engineered with mRNA for expression of a EphA2-targeted CAR

Lam, Pui Yeng, Omer, Natacha, Wong, Josh K. M., Tu, Cui, Alim, Louisa, Rossi, Gustavo R., Victorova, Maria, Tompkins, Hannah, Lin, Cheng-Yu, Mehdi, Ahmed M., Choo, Amos, Elliott, Melissa R., Coleborn, Elaina, Sun, Jane, Mercer, Timothy, Vittorio, Orazio, Dobson, Lachlan J., Mclellan, Alexander D., Brooks, Andrew, Tuong, Zewen Kelvin, Cheetham, Seth W., Nicholls, Wayne and Souza-Fonseca-Guimaraes, Fernando (2025). Enhancement of anti-sarcoma immunity by NK cells engineered with mRNA for expression of a EphA2-targeted CAR. Clinical and Translational Medicine, 15 (1) e70140, 1-21. doi: 10.1002/ctm2.70140

Enhancement of anti-sarcoma immunity by NK cells engineered with mRNA for expression of a EphA2-targeted CAR

2025

Journal Article

Engineered iPSC‐derived natural killer cells: recent innovations in translational innate anti‐cancer immunotherapy

Sun, Jane, Elliott, Melissa and Souza‐Fonseca‐Guimaraes, Fernando (2025). Engineered iPSC‐derived natural killer cells: recent innovations in translational innate anti‐cancer immunotherapy. Clinical and Translational Immunology, 14 (7) e70045, 1-15. doi: 10.1002/cti2.70045

Engineered iPSC‐derived natural killer cells: recent innovations in translational innate anti‐cancer immunotherapy

2025

Conference Publication

Probing extracellular vesicle interactions with lipoproteins in healthy and disease contexts

Ghebosu, Raluca, Pendiuk Goncalves, Jenifer, Fitri, Nur Indah, Iannotta, Dalila, Sharifpour, Mohammad Farouq, Coleborn, Elaina, Loukas, Alex, Souza-Fonseca-Guimaraes, Fernando and Wolfram, Joy (2025). Probing extracellular vesicle interactions with lipoproteins in healthy and disease contexts. International Society for Extracellular Vesicles Annual Meeting, Vienna, Austria, 23-27 April 2025.

Probing extracellular vesicle interactions with lipoproteins in healthy and disease contexts

2024

Conference Publication

Unravelling immune mechanisms and precision therapies for cancers and infectious diseases

Souza-Fonseca-Guimaraes, Fernando (2024). Unravelling immune mechanisms and precision therapies for cancers and infectious diseases. Multi-Omics 2024, Brisbane, QLD, Australia, 1-3 December 2024.

Unravelling immune mechanisms and precision therapies for cancers and infectious diseases

2024

Conference Publication

Advances in NK cell biology

Souza-Fonseca-Guimaraes, Fernando (2024). Advances in NK cell biology. Australasian Society of Immunology - Annual Meeting, Sydney, NSW, Australia, 26-29 November 2024.

Advances in NK cell biology

2024

Conference Publication

Towards immunotherapy development for bacterial infection

Souza-Fonseca-Guimaraes, Fernando (2024). Towards immunotherapy development for bacterial infection. Australian Infectious Diseases Research Centre - 2024 Symposium, Brisbane, QLD, Australia, 21 November 2024.

Towards immunotherapy development for bacterial infection

2024

Journal Article

Dichotomous outcomes of TNFR1 and TNFR2 signaling in NK cell-mediated immune responses during inflammation

McCulloch, Timothy R., Rossi, Gustavo R., Alim, Louisa, Lam, Pui Yeng, Wong, Joshua K. M., Coleborn, Elaina, Kumari, Snehlata, Keane, Colm, Kueh, Andrew J., Herold, Marco J., Wilhelm, Christoph, Knolle, Percy A., Kane, Lawrence, Wells, Timothy J. and Souza-Fonseca-Guimaraes, Fernando (2024). Dichotomous outcomes of TNFR1 and TNFR2 signaling in NK cell-mediated immune responses during inflammation. Nature Communications, 15 (1) 9871, 1-16. doi: 10.1038/s41467-024-54232-y

Dichotomous outcomes of TNFR1 and TNFR2 signaling in NK cell-mediated immune responses during inflammation

2024

Conference Publication

Natural killer cell-based therapy for sarcoma

Souza-Fonseca-Guimaraes, Fernando (2024). Natural killer cell-based therapy for sarcoma. 2024 Sarcoma Symposium, Sydney, NSW, Australia, 8 Nov 2024.

Natural killer cell-based therapy for sarcoma

2024

Conference Publication

Unlocking the anti-cancer immunity: advancements in immunotherapy against sarcoma

Souza-Fonseca-Guimaraes, Fernando (2024). Unlocking the anti-cancer immunity: advancements in immunotherapy against sarcoma. 22nd International Society of Limb Salvage General Meeting, Brisbane, QLD, Australia, 11-13 October 2024.

Unlocking the anti-cancer immunity: advancements in immunotherapy against sarcoma

2024

Journal Article

A scalable, spin‐free approach to generate enhanced induced pluripotent stem cell–derived natural killer cells for cancer immunotherapy

Rossi, Gustavo R., Sun, Jane, Lin, Cheng‐Yu, Wong, Joshua K.M., Alim, Louisa, Lam, Pui Yeng, Khosrotehrani, Kiarash, Wolvetang, Ernst, Cheetham, Seth W., Derrick, Emily B., Amoako, Akwasi, Lehner, Christoph, Brooks, Andrew J., Beavis, Paul A. and Souza‐Fonseca‐Guimaraes, Fernando (2024). A scalable, spin‐free approach to generate enhanced induced pluripotent stem cell–derived natural killer cells for cancer immunotherapy. Immunology & Cell Biology, 102 (10), 1-11. doi: 10.1111/imcb.12820

A scalable, spin‐free approach to generate enhanced induced pluripotent stem cell–derived natural killer cells for cancer immunotherapy

2024

Journal Article

The current molecular and cellular landscape of chronic obstructive pulmonary disease (COPD): a review of therapies and efforts towards personalized treatment

Farrell, Luke A., O’Rourke, Matthew B., Padula, Matthew P., Souza-Fonseca-Guimaraes, Fernando, Caramori, Gaetano, Wark, Peter A. B., Dharmage, Shymali C. and Hansbro, Phillip M. (2024). The current molecular and cellular landscape of chronic obstructive pulmonary disease (COPD): a review of therapies and efforts towards personalized treatment. Proteomes, 12 (3) 23, 1-31. doi: 10.3390/proteomes12030023

The current molecular and cellular landscape of chronic obstructive pulmonary disease (COPD): a review of therapies and efforts towards personalized treatment

2024

Other Outputs

Potential new treatment pathway for bladder cancer

Guimaraes, Fernando S. F. (2024, 08 21). Potential new treatment pathway for bladder cancer UQ News

Potential new treatment pathway for bladder cancer

2024

Conference Publication

Trastuzumab-induced cardiotoxicity involves antibody dependent cell cytotoxicity (ADCC)

Griffiths, L., Ho, U., Burt, K., Watson, S., Patel, K., Bradford, J., Tan, C., Bhavsar, C., Palpant, N., Souza-Fonseca-Guimaraes, F., Wu, S., Reichelt, M. and Thomas, W. (2024). Trastuzumab-induced cardiotoxicity involves antibody dependent cell cytotoxicity (ADCC). 72nd Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, Perth, WA Australia, 1-4 August 2024. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2024.06.397

Trastuzumab-induced cardiotoxicity involves antibody dependent cell cytotoxicity (ADCC)

2024

Journal Article

Highlight of 2023: Unlocking the therapeutic potential of natural killer cells—advances in adaptive functions, cellular engineering and immunotherapy

Lam, Pui Yeng and Souza‐Fonseca‐Guimaraes, Fernando (2024). Highlight of 2023: Unlocking the therapeutic potential of natural killer cells—advances in adaptive functions, cellular engineering and immunotherapy. Immunology and Cell Biology, 102 (6), 444-447. doi: 10.1111/imcb.12769

Highlight of 2023: Unlocking the therapeutic potential of natural killer cells—advances in adaptive functions, cellular engineering and immunotherapy

2024

Journal Article

The immune checkpoint TIGIT is upregulated on T cells during bacterial infection and is a potential target for immunotherapy

McCulloch, Timothy R., Rossi, Gustavo R., Miranda‐Hernandez, Socorro, Valencia‐Hernandez, Ana Maria, Alim, Louisa, Belle, Clemence J., Krause, Andrew, Zacchi, Lucia F., Lam, Pui Yeng, Nakamura, Kyohei, Kupz, Andreas, Wells, Timothy J. and Souza‐Fonseca‐Guimaraes, Fernando (2024). The immune checkpoint TIGIT is upregulated on T cells during bacterial infection and is a potential target for immunotherapy. Immunology and Cell Biology, 102 (8), 721-733. doi: 10.1111/imcb.12794

The immune checkpoint TIGIT is upregulated on T cells during bacterial infection and is a potential target for immunotherapy

2024

Journal Article

TGF-β signalling limits effector function capacity of NK cell anti-tumour immunity in human bladder cancer

Wong, Joshua K. M., McCulloch, Timothy R., Alim, Louisa, Omer, Natacha, Mehdi, Ahmed M., Tuong, Zewen Kelvin, Bonfim-Melo, Alexis, Chung, Eric, Nicol, Alice, Simpson, Fiona, Rhee, Handoo, Rossi, Gustavo Rodrigues and Souza-Fonseca-Guimaraes, Fernando (2024). TGF-β signalling limits effector function capacity of NK cell anti-tumour immunity in human bladder cancer. EBioMedicine, 104 105176, 1-15. doi: 10.1016/j.ebiom.2024.105176

TGF-β signalling limits effector function capacity of NK cell anti-tumour immunity in human bladder cancer

2024

Conference Publication

Natural Killer cell-based cancer immunotherapy for rhabdomyosarcoma

Rossi, Gustavo Rodrigues, Lam, Pui Yeng, Omer, Natacha, Tu, Cui and Souza-Fonseca-Guimaraes, Fernando (2024). Natural Killer cell-based cancer immunotherapy for rhabdomyosarcoma. Annual Meeting of the American Association of Immunologists (IMMUNOLOGY), Chicago, IL, United States, 3-7 May 2024. Cary, NC, United States: Oxford University Press. doi: 10.4049/jimmunol.212.supp.1399.5214

Natural Killer cell-based cancer immunotherapy for rhabdomyosarcoma

2024

Conference Publication

TGF-β signaling limits effector function capacity of NK cell anti-cancer immunity in human bladder cancer

Wong, Joshua, Rossi, Gustavo Rodrigues and Guimaraes, Fernando (2024). TGF-β signaling limits effector function capacity of NK cell anti-cancer immunity in human bladder cancer. Annual Meeting of the American Association of Immunologists (IMMUNOLOGY), Chicago, IL, United States, 3-7 May 2024. Cary, NC, United States: Oxford University Press. doi: 10.4049/jimmunol.212.supp.1431.4524

TGF-β signaling limits effector function capacity of NK cell anti-cancer immunity in human bladder cancer

2024

Conference Publication

Spatial profiling of pediatric rhabdomyosarcoma to elucidate their immunosuppressive tumor microenvironment

Tu, Cui, Tan, Chin Wee, Liu, Ning, Kulasinghe, Arutha and Souza-Fonseca-Guimaraes, Fernando (2024). Spatial profiling of pediatric rhabdomyosarcoma to elucidate their immunosuppressive tumor microenvironment. American Association for Cancer Research Annual Meeting 2024, San Diego, CA United States, 5-10 April 2024. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2024-73

Spatial profiling of pediatric rhabdomyosarcoma to elucidate their immunosuppressive tumor microenvironment

2024

Journal Article

In situ single-cell profiling sheds light on IFI27 localisation during SARS-CoV-2 infection

Tan, Chin Wee, Chen, Jinjin, Liu, Ning, Bhuva, Dharmesh D., Blick, Tony, Monkman, James, Cooper, Caroline, Kharbanda, Malvika, Feher, Kristen, Phipson, Belinda, Killingbeck, Emily E., Pan, Liuliu, Kim, Youngmi, Liang, Yan, Nam, Andy, Leon, Michael, Souza-Fonseca-Guimaraes, Paulo, Nagashima, Seigo, Camargo Martins, Ana Paula, Machado-Souza, Cleber, de Noronha, Lucia, Tang, Benjamin, Short, Kirsty, Fraser, John, Belz, Gabrielle T., Souza-Fonseca-Guimaraes, Fernando, Kulasinghe, Arutha and Davis, Melissa J. (2024). In situ single-cell profiling sheds light on IFI27 localisation during SARS-CoV-2 infection. eBioMedicine, 101 105016, 1-4. doi: 10.1016/j.ebiom.2024.105016

In situ single-cell profiling sheds light on IFI27 localisation during SARS-CoV-2 infection