2023 Journal Article Copper chelation suppresses epithelial-mesenchymal transition by inhibition of canonical and non-canonical TGF-β signaling pathways in cancerPoursani, Ensieh M., Mercatelli, Daniele, Raninga, Prahlad, Bell, Jessica L., Saletta, Federica, Kohane, Felix V., Neumann, Daniel P., Zheng, Ye, Rouaen, Jourdin R. C., Jue, Toni Rose, Michniewicz, Filip T., Schadel, Piper, Kasiou, Erin, Tsoli, Maria, Cirillo, Giuseppe, Waters, Shafagh, Shai-Hee, Tyler, Cazzoli, Riccardo, Brettle, Merryn, Slapetova, Iveta, Kasherman, Maria, Whan, Renee, Souza-Fonseca-Guimaraes, Fernando, Vahdat, Linda, Ziegler, David, Lock, John G., Giorgi, Federico M., Khanna, KumKum and Vittorio, Orazio (2023). Copper chelation suppresses epithelial-mesenchymal transition by inhibition of canonical and non-canonical TGF-β signaling pathways in cancer. Cell and Bioscience, 13 (1) 132, 132. doi: 10.1186/s13578-023-01083-7 |
2023 Conference Publication TIGIT limits anti-bacterial immunity and is a potential target for immunotherapySouza-Fonseca-Guimaraes, Fernando, Rossi, Gustavo Rodrigues, Wells, Timothy and McCulloch, Timothy Ryan (2023). TIGIT limits anti-bacterial immunity and is a potential target for immunotherapy. IMMUNOLOGY2023™ Meeting, Washington, DC, United States, 11 - 15 May 2023. Rockville, MD, United States: The American Association of Immunologists. doi: 10.4049/jimmunol.210.supp.64.14 |
2023 Conference Publication Differential regulation of natural killer cells by tumor necrosis factor receptors 1 and 2McCulloch, Timothy R., Rossi, Gustavo Rodrigues, Lam, Allie, Wong, Joshua, Kane, Lawrence P., Herold, Marco, Wells, Timothy and Souza-Fonseca-Guimaraes, Fernando (2023). Differential regulation of natural killer cells by tumor necrosis factor receptors 1 and 2. Immunology 2023™ Meeting, Washington, DC United States, 11-15 May 2023. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.210.supp.72.28 |
2023 Journal Article Oncogenic drivers dictate immune control of acute myeloid leukemiaAustin, Rebecca J., Straube, Jasmin, Halder, Rohit, Janardhanan, Yashaswini, Bruedigam, Claudia, Witkowski, Matthew, Cooper, Leanne, Porter, Amy, Braun, Matthias, Souza-Fonseca-Guimaraes, Fernando, Minnie, Simone A., Cooper, Emily, Jacquelin, Sebastien, Song, Axia, Bald, Tobias, Nakamura, Kyohei, Hill, Geoffrey R., Aifantis, Iannis, Lane, Steven W. and Bywater, Megan J. (2023). Oncogenic drivers dictate immune control of acute myeloid leukemia. Nature Communications, 14 (1) 2155, 1-14. doi: 10.1038/s41467-023-37592-9 |
2023 Journal Article Weaponizing natural killer cells for solid cancer immunotherapyWong, Joshua K.M., Dolcetti, Riccardo, Rhee, Handoo, Simpson, Fiona and Souza-Fonseca-Guimaraes, Fernando (2023). Weaponizing natural killer cells for solid cancer immunotherapy. Trends in Cancer, 9 (2), 111-121. doi: 10.1016/j.trecan.2022.10.009 |
2023 Journal Article IFI27 transcription is an early predictor for COVID-19 outcomes, a multi-cohort observational studyShojaei, Maryam, Shamshirian, Amir, Monkman, James, Grice, Laura, Tran, Minh, Tan, Chin Wee, Teo, Siok Min, Rodrigues Rossi, Gustavo, McCulloch, Timothy R., Nalos, Marek, Raei, Maedeh, Razavi, Alireza, Ghasemian, Roya, Gheibi, Mobina, Roozbeh, Fatemeh, Sly, Peter D., Spann, Kirsten M., Chew, Keng Yih, Zhu, Yanshan, Xia, Yao, Wells, Timothy J., Senegaglia, Alexandra Cristina, Kuniyoshi, Carmen Lúcia, Franck, Claudio Luciano, dos Santos, Anna Flavia Ribeiro, Noronha, Lucia de, Motamen, Sepideh, Valadan, Reza, Amjadi, Omolbanin ... Tang, Benjamin (2023). IFI27 transcription is an early predictor for COVID-19 outcomes, a multi-cohort observational study. Frontiers in Immunology, 13 1060438, 1-14. doi: 10.3389/fimmu.2022.1060438 |
2022 Journal Article CIS controls the functional polarization of GM-CSF-derived macrophagesZhang, Shengbo, Rautela, Jai, Bediaga, Naiara G., Kolesnik, Tatiana B., You, Yue, Nie, Junli, Dagley, Laura F., Bedo, Justin, Wang, Hanqing, Sun, Li, Sutherland, Robyn, Surgenor, Elliot, Iannarella, Nadia, Allan, Rhys, Souza-Fonseca-Guimaraes, Fernando, Xie, Yi, Wang, Qike, Zhang, Yuxia, Xu, Yuekang, Nutt, Stephen L., Lew, Andrew M., Huntington, Nicholas D., Nicholson, Sandra E., Chopin, Michaël and Zhan, Yifan (2022). CIS controls the functional polarization of GM-CSF-derived macrophages. Cellular and Molecular Immunology, 20 (1), 65-79. doi: 10.1038/s41423-022-00957-z |
2022 Conference Publication Deep single-cell, proteogenomic insights from SARS-CoV-2 infected lung tissuesKulasinghe, Arutha, Tan, Chin Wee, Liu, Ning, Monkman, James, Killingbeck, Emily, Kim, Youngmi, Pan, Liuliu, Blick, Tony, Bhuva, Dharmesh, Feher, Kristen, Leon, Michael, Gregory, Mark, Short, Kirsty, Guimaraes, Fernando, Rhodes, Michael, Belz, Gabrielle and Davis, Melissa (2022). Deep single-cell, proteogenomic insights from SARS-CoV-2 infected lung tissues. SITC 37th Annual Meeting (SITC 2022), Boston, MA USA, 8-12 November 2022. London, United Kingdom: BMJ Publishing Group. doi: 10.1136/jitc-2022-sitc2022.0923 |
2022 Journal Article Clustering ICU patients with sepsis based on the patterns of their circulating biomarkers: A secondary analysis of the CAPTAIN prospective multicenter cohort studyMisset, Benoît, Philippart, François, Fitting, Catherine, Bedos, Jean-Pierre, Diehl, Jean-Luc, Hamzaoui, Olfa, Annane, Djillali, Journois, Didier, Parlato, Marianna, Moucadel, Virginie, Cavaillon, Jean-Marc, Coste, Joël, Jacqmin, Sébastien, Journois, Didier, Lagrange, Alix, Pinot de Ville-Chenon, Gabrielle, Aissaoui, Nadia, Diehl, Jean-Luc, Guerot, Emmanuel, Venot, Marion, Hamzaoui, Olfa, Prat, Dominique, Sztrymf, Benjamin, Annane, Djillali, Maxime, Virginie, Polito, Andrea, Bouhemad, Belaïd, Bruel, Cédric, Ethuin, Frédéric ... Souza-Fonseca-Guimaraes, Fernando (2022). Clustering ICU patients with sepsis based on the patterns of their circulating biomarkers: A secondary analysis of the CAPTAIN prospective multicenter cohort study. PLoS One, 17 (10) e0267517, 1-17. doi: 10.1371/journal.pone.0267517 |
2022 Journal Article The cancer cell-derived extracellular vesicle glycocode in immunoevasionGoncalves, Jenifer P., Deliwala, Vatsal J., Kolarich, Daniel, Souza-Fonseca-Guimaraes, Fernando and Wolfram, Joy (2022). The cancer cell-derived extracellular vesicle glycocode in immunoevasion. Trends in Immunology, 43 (11), 864-867. doi: 10.1016/j.it.2022.09.004 |
2022 Journal Article Transcriptomic profiling of cardiac tissues from SARS‐CoV ‐2 patients identifies DNA damageKulasinghe, Arutha, Liu, Ning, Tan, Chin Wee, Monkman, James, Sinclair, Jane E., Bhuva, Dharmesh D., Godbolt, David, Pan, Liuliu, Nam, Andy, Sadeghirad, Habib, Sato, Kei, Bassi, Gianluigi Li, O'Byrne, Ken, Hartmann, Camila, Miggiolaro, Anna Flavia Ribeiro dos Santos, Marques, Gustavo Lenci, Moura, Lidia Zytynski, Richard, Derek, Adams, Mark, Noronha, Lucia de, Baena, Cristina Pellegrino, Suen, Jacky Y., Arora, Rakesh, Belz, Gabrielle T., Short, Kirsty R., Davis, Melissa J., Souza‐Fonseca Guimaraes, Fernando and Fraser, John F. (2022). Transcriptomic profiling of cardiac tissues from SARS‐CoV ‐2 patients identifies DNA damage. Immunology, 168 (3), 403-419. doi: 10.1111/imm.13577 |
2022 Journal Article Nanobiomaterials to modulate natural killer cell responses for effective cancer immunotherapyRaza, Aun, Rossi, Gustavo Rodrigues, Janjua, Taskeen Iqbal, Souza-Fonseca-Guimaraes, Fernando and Popat, Amirali (2022). Nanobiomaterials to modulate natural killer cell responses for effective cancer immunotherapy. Trends in Biotechnology, 41 (1), 77-92. doi: 10.1016/j.tibtech.2022.06.011 |
2022 Journal Article TGF-β and CIS inhibition overcomes NK cell suppression to restore anti-tumor immunitySouza-Fonseca Guimaraes, Fernando, Rossi, Gustavo R., Dagley, Laura F., Foroutan, Momeneh, McCulloch, Timothy R., Yousef, Jumana, Park, Hae-Young, Gunter, Jennifer H., Beavis, Paul A., Lin, Cheng-Yu, Hediyeh-zadeh, Soroor, Camilleri, Tania, Davis, Melissa J. and Huntington, Nicholas D. (2022). TGF-β and CIS inhibition overcomes NK cell suppression to restore anti-tumor immunity. Cancer Immunology Research, 10 (9), 1047-1054. doi: 10.1158/2326-6066.cir-21-1052 |
2022 Journal Article Editorial: Cancer Immunotherapies: From Efficacy to Resistance MechanismsChandra, Janin, Hansen, Morten, Labarriere, Nathalie, Marigo, Ilaria, Souza-Fonseca-Guimaraes, Fernando, Vujanovic, Lazar, Koguchi, Yoshinobu and Jacquelot, Nicolas (2022). Editorial: Cancer Immunotherapies: From Efficacy to Resistance Mechanisms. Frontiers in Immunology, 13 939789, 939789. doi: 10.3389/fimmu.2022.939789 |
2022 Journal Article CIS and TGF ‐β regulatory pathways influence immunity to bacterial infectionMcCulloch, Timothy R., Rossi, Gustavo R., Schreuder, Jaring, Belz, Gabrielle T., Wells, Timothy J. and Souza‐Fonseca‐Guimaraes, Fernando (2022). CIS and TGF ‐β regulatory pathways influence immunity to bacterial infection. Immunology, 167 (1), 54-63. doi: 10.1111/imm.13516 |
2022 Conference Publication TGF-β and CIS inhibition synergistically enhance natural killer cell-based immunitySouza-Fonseca-Guimaraes, Fernando (2022). TGF-β and CIS inhibition synergistically enhance natural killer cell-based immunity. Immunology 2022 Meeting, Portland, OR United States, 6-10 May 2022. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.208.supp.164.01 |
2022 Conference Publication Mapping the spatial biology of COVID-19 immunopathology in placenta tissuesMa, Ning, Braubach, Oliver, Rebutini, Patricia Zadorosnei, Machado-Souza, Cleber, Stonoga, Emanuele Therezinha Schueda, de Noronha, Lucia, Souza-Fonseca-Guimaraes, Fernando and Kulasinghe, Arutha (2022). Mapping the spatial biology of COVID-19 immunopathology in placenta tissues. Immunology 2022 Meeting, Portland, OR United States, 6-10 May 2022. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.208.supp.125.20 |
2022 Journal Article Profiling of lung SARS-CoV-2 and influenza virus infection dissects virus-specific host responses and gene signaturesKulasinghe, Arutha, Tan, Chin Wee, dos Santos Miggiolaro, Anna Flavia Ribeiro, Monkman, James, SadeghiRad, Habib, Bhuva, Dharmesh D., da Silva Motta Junior, Jarbas, Vaz de Paula, Caroline Busatta, Nagashima, Seigo, Baena, Cristina Pellegrino, Souza-Fonseca-Guimaraes, Paulo, de Noronha, Lucia, McCulloch, Timothy, Rodrigues Rossi, Gustavo, Cooper, Caroline, Tang, Benjamin, Short, Kirsty R., Davis, Melissa J., Souza-Fonseca-Guimaraes, Fernando, Belz, Gabrielle T. and O'Byrne, Ken (2022). Profiling of lung SARS-CoV-2 and influenza virus infection dissects virus-specific host responses and gene signatures. European Respiratory Journal, 59 (6) 2101881, 1-19. doi: 10.1183/13993003.01881-2021 |
2021 Journal Article Transcriptome sequencing and multi-plex imaging of prostate cancer microenvironment reveals a dominant role for monocytic cells in progressionMangiola, Stefano, McCoy, Patrick, Modrak, Martin, Souza-Fonseca-Guimaraes, Fernando, Blashki, Daniel, Stuchbery, Ryan, Keam, Simon P., Kerger, Michael, Chow, Ken, Nasa, Chayanica, Le Page, Melanie, Lister, Natalie, Monard, Simon, Peters, Justin, Dundee, Phil, Williams, Scott G., Costello, Anthony J., Neeson, Paul J., Pal, Bhupinder, Huntington, Nicholas D., Corcoran, Niall M., Papenfuss, Anthony T. and Hovens, Christopher M. (2021). Transcriptome sequencing and multi-plex imaging of prostate cancer microenvironment reveals a dominant role for monocytic cells in progression. BMC Cancer, 21 (1) 846, 846. doi: 10.1186/s12885-021-08529-6 |
2021 Other Outputs Salmonella Typhimurium infection drives NK cell loss and conversion to ILC1-like cells, and CIS inhibition enhances antibacterial immunityMcCulloch, Timothy R., Rossi, Gustavo R., Wells, Timothy J. and Souza-Fonseca-Guimaraes, Fernando (2021). Salmonella Typhimurium infection drives NK cell loss and conversion to ILC1-like cells, and CIS inhibition enhances antibacterial immunity. doi: 10.1101/2021.11.29.470332 |