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2016

Journal Article

Anti-CD137 enhances anti-CD20 therapy of systemic B-cell lymphoma with altered immune homeostasis but negligible toxicity

Souza-Fonseca-Guimaraes, Fernando, Blake, Stephen J., Makkouk, Amani, Chester, Cariad, Kohrt, Holbrook E. and Smyth, Mark J. (2016). Anti-CD137 enhances anti-CD20 therapy of systemic B-cell lymphoma with altered immune homeostasis but negligible toxicity. OncoImmunology, 5 (7) e1192740, e1192740. doi: 10.1080/2162402X.2016.1192740

Anti-CD137 enhances anti-CD20 therapy of systemic B-cell lymphoma with altered immune homeostasis but negligible toxicity

2016

Conference Publication

Resolving T helper cell fate decisions using single-cell RNA-sequencing

Loennberg, Tapio, James, Kylie, Svensson, Valentine, Fernandez-Ruiz, Daniel, Sebina, Ismail, Montandon, Ruddy, Soon, Megan, Stubbington, Michael, Souza-Fonseca-Guimaraes, Fernando, Heath, William, Billker, Oliver, Haque, Ashraful and Teichmann, Sarah (2016). Resolving T helper cell fate decisions using single-cell RNA-sequencing. 43rd Meeting of the Scandinavian Society for Immunology (SSI), Turku, Finland, 10-13 May 2016. Chichester, West Sussex United Kingdom: Wiley-Blackwell Publishing.

Resolving T helper cell fate decisions using single-cell RNA-sequencing

2016

Conference Publication

Autophagy-dependent TIGIT+ Treg are critical for the maintenance of tolerance

MacDonald, Kelli P. A., Le Texier, Laetitia, Leveque-ElMouttie, Lucie, Lineburg, Katie, Nicholls, Jemma, Guimaraes, Fernando Souza-Fonseca, Alexander, Kylie, Clouston, Andrew, Blazar, Bruce R. and Hill, Geoff R. (2016). Autophagy-dependent TIGIT+ Treg are critical for the maintenance of tolerance. Immunology 2016 Meeting, Seattle, WA United States, 13-17 May 2016. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.196.supp.125.14

Autophagy-dependent TIGIT+ Treg are critical for the maintenance of tolerance

2016

Journal Article

NK cell-based immunotherapies: awakening the innate anti-cancer response

Souza-Fonseca-Guimaraes, Fernando (2016). NK cell-based immunotherapies: awakening the innate anti-cancer response. Discovery Medicine, 21 (115), 197-203.

NK cell-based immunotherapies: awakening the innate anti-cancer response

2016

Journal Article

TGF-beta inhibits the activation and functions of NK cells by repressing the mTOR pathway

Viel, Sebastien, Marcais, Antoine, Guimaraes, Fernando Souza-Fonseca, Loftus, Roisin, Rabilloud, Jessica, Grau, Morgan, Degouve, Sophie, Djebali, Sophia, Sanlaville, Amelien, Charrier, Emily, Bienvenu, Jacques, Marie, Julien C., Caux, Christophe, Marvel, Jacqueline, Town, Liam, Huntington, Nicholas D., Bartholin, Laurent, Finlay, David, Smyth, Mark J. and Walzer, Thierry (2016). TGF-beta inhibits the activation and functions of NK cells by repressing the mTOR pathway. Science Signaling, 9 (415) ra19, ra19-ra19. doi: 10.1126/scisignal.aad1884

TGF-beta inhibits the activation and functions of NK cells by repressing the mTOR pathway

2016

Journal Article

Pravastatina induz parada no ciclo celular e diminuição na produção de VEGF e bFGF em linhagem de mieloma multiplo

Trojan, P. J.J., Bohatch-Junior, M. S., Otuki, M. F., Souza-Fonseca-Guimarães, F., Svidnicki, P. V., Nogaroto, V., Fernandes, D., Krum, E. A. and Favero, G. M. (2016). Pravastatina induz parada no ciclo celular e diminuição na produção de VEGF e bFGF em linhagem de mieloma multiplo. Brazilian Journal of Biology, 76 (1), 59-65. doi: 10.1590/1519-6984.11914

Pravastatina induz parada no ciclo celular e diminuição na produção de VEGF e bFGF em linhagem de mieloma multiplo

2016

Conference Publication

EphA2KO mice survive longer in a mouse model of sepsis

Kumar, V., Woodruff, T., Ting, M., Boyd, A., Coulthard, M., Souza-Fonseca-Guimaraes, F. and Smyth, M. (2016). EphA2KO mice survive longer in a mouse model of sepsis. International Congress of Immunology (ICI), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley - VCH. doi: 10.1002/eji.201670200

EphA2KO mice survive longer in a mouse model of sepsis

2016

Conference Publication

Adenosine impairs the proliferative capacity of terminally mature NK cells

Young, A., Souza-Fonseca-Guimaraes, F., Ngiow, S. F., Gao, Y., Linden, J., Huntington, N. D. and Smyth, M. J. (2016). Adenosine impairs the proliferative capacity of terminally mature NK cells. International Congress of Immunology (ICI), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley - VCH. doi: 10.1002/eji.201670200

Adenosine impairs the proliferative capacity of terminally mature NK cells

2015

Journal Article

Bench to bedside: NK cells and control of metastasis

Krasnova, Yelena, Putz, Eva Maria, Smyth, Mark J. and Souza-Fonseca-Guimaraes, Fernando (2015). Bench to bedside: NK cells and control of metastasis. Clinical Immunology, 177, 50-59. doi: 10.1016/j.clim.2015.10.001

Bench to bedside: NK cells and control of metastasis

2015

Journal Article

DNAM-1 expression marks an alternative program of NK cell maturation

Martinet, Ludovic, FerrariDeAndrade, Lucas, Guillerey, Camille, Lee, Jason S, Liu, Jing, Souza-Fonseca-Guimaraes, Fernando, Hutchinson, Dana S, Kolesnik, Tatiana B, Nicholson, Sandra E, Huntington, Nicholas D and Smyth, Mark J (2015). DNAM-1 expression marks an alternative program of NK cell maturation. Cell Reports, 11 (1), 85-97. doi: 10.1016/j.celrep.2015.03.006

DNAM-1 expression marks an alternative program of NK cell maturation

2015

Journal Article

CD3 bright signals on γδ T cells identify IL-17A-producing Vγ6Vδ1+T cells

Paget, C., Chow, M. T., Gherardin, N. A., Beavis, P. A., Uldrich, A. P., Duret, H., Hassane, M., Souza-Fonseca-Guimaraes, F., Mogilenko, D. A., Staumont-Salle, D., Escalante, N. K., Hill, G. R., Neeson, P., Ritchie, D. S., Dombrowicz, D., Mallevaey, T., Trottein, F., Belz, G. T., Godfrey, D. I. and Smyth, M. J. (2015). CD3 bright signals on γδ T cells identify IL-17A-producing Vγ6Vδ1+T cells. Immunology and Cell Biology, 93 (2), 198-212. doi: 10.1038/icb.2014.94

CD3 bright signals on γδ T cells identify IL-17A-producing Vγ6Vδ1+T cells

2015

Journal Article

IFN type III: In vivo NK cell response

Souza-Fonseca-Guimaraes, Fernando, Young, Arabella and Smyth, Mark J. (2015). IFN type III: In vivo NK cell response. Oncotarget, 6 (24), 19960-19961. doi: 10.18632/oncotarget.4758

IFN type III: In vivo NK cell response

2014

Journal Article

Innate immunodeficiency following genetic ablation of Mcl1 in natural killer cells

Sathe, Priyanka, Delconte, Rebecca B., Souza-Fonseca-Guimaraes, Fernando, Seillet, Cyril, Chopin, Michael, Vandenberg, Cassandra J., Rankin, Lucille C., Mielke, Lisa A., Vikstrom, Ingela, Kolesnik, Tatiana B., Nicholson, Sandra E., Vivier, Eric, Smyth, Mark J., Nutt, Stephen L., Glaser, Stefan P., Strasser, Andreas, Belz, Gabrielle T., Carotta, Sebastian and Huntington, Nicholas D. (2014). Innate immunodeficiency following genetic ablation of Mcl1 in natural killer cells. Nature Communications, 5 (1) 4539, 1-10. doi: 10.1038/ncomms5539

Innate immunodeficiency following genetic ablation of Mcl1 in natural killer cells

2014

Journal Article

TLR-mediated activation of NK cells and their role in bacterial/viral immune responses in mammals

Adib-Conquy, Minou, Scott-Algara, Daniel, Cavaillon, Jean-Marc and Souza-Fonseca-Guimaraes, Fernando (2014). TLR-mediated activation of NK cells and their role in bacterial/viral immune responses in mammals. Immunology and Cell Biology, 92 (3), 256-262. doi: 10.1038/icb.2013.99

TLR-mediated activation of NK cells and their role in bacterial/viral immune responses in mammals

2014

Journal Article

CD24-triggered caspase-dependent apoptosis via mitochondrial membrane depolarization and reactive oxygen species production of human neutrophils is impaired in sepsis

Parlato, Marianna, Souza-Fonseca-Guimaraes, Fernando, Philippart, François, Misset, Benoît, Adib-Conquy, Minou and Cavaillon, Jean-Marc (2014). CD24-triggered caspase-dependent apoptosis via mitochondrial membrane depolarization and reactive oxygen species production of human neutrophils is impaired in sepsis. Journal of Immunology, 192 (5), 2449-2459. doi: 10.4049/jimmunol.1301055

CD24-triggered caspase-dependent apoptosis via mitochondrial membrane depolarization and reactive oxygen species production of human neutrophils is impaired in sepsis

2014

Conference Publication

Checkpoints and interferons in tumor control

Souza-Fonseca-Guimaraes, Fernando, Martinet, Ludovic, Hill, Geoffrey R., Teng, Michele W. L. and Smyth, Mark (2014). Checkpoints and interferons in tumor control. 2nd Annual Meeting of the International-Cytokine-and-Interferon-Society (ICIS), Melbourne, Australia, 26-29 October 2014. LONDON: ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD. doi: 10.1016/j.cyto.2014.07.244

Checkpoints and interferons in tumor control

2014

Journal Article

The receptors CD96 and CD226 oppose each other in the regulation of natural killer cell functions

Chan, Christopher J., Martinet, Ludovic, Gilfillan, Susan, Souza-Fonseca-Guimaraes, Fernando, Chow, Melvyn T., Town, Liam, Ritchie, David S., Colonna, Marco, Andrews, Daniel M. and Smyth, Mark J. (2014). The receptors CD96 and CD226 oppose each other in the regulation of natural killer cell functions. Nature Immunology, 15 (5), 431-438. doi: 10.1038/ni.2850

The receptors CD96 and CD226 oppose each other in the regulation of natural killer cell functions

2013

Journal Article

Highly diluted natural complex M-1 inhibits melanoma growth in vivo

de Andrade, Lucas Ferrari, Biscaia, Stellee Marcela Petris, Rossi, Gustavo, Leck, Aline Raquell, da Costa, Cleber Rafael Vieira, Mozeleski, Brian, de Souza Fonseca Guimarães, Fernando, Zotz, Rafael, Gabardo, Juarez, de Oliveira, Carolina Camargo, de Freitas Buchi, Dorly and da Silva Trindade, Edvaldo (2013). Highly diluted natural complex M-1 inhibits melanoma growth in vivo. International Journal of High Dilution Research, 12 (44), 95-97.

Highly diluted natural complex M-1 inhibits melanoma growth in vivo

2013

Journal Article

Bench-to-bedside review: natural killer cells in sepsis - guilty or not guilty?

Souza-Fonseca-Guimaraes, Fernando, Cavaillon, Jean-Marc and Adib-Conquy, Minou (2013). Bench-to-bedside review: natural killer cells in sepsis - guilty or not guilty?. Critical Care, 17 (4) 235. doi: 10.1186/cc12700

Bench-to-bedside review: natural killer cells in sepsis - guilty or not guilty?

2013

Journal Article

In the spotlight: myeloid TGF-beta responsiveness promotes metastases

Souza-Fonseca-Guimaraes, Fernando and Smyth, Mark J. (2013). In the spotlight: myeloid TGF-beta responsiveness promotes metastases. Cancer Discovery, 3 (8), 846-848. doi: 10.1158/2159-8290.CD-13-0271

In the spotlight: myeloid TGF-beta responsiveness promotes metastases