Skip to menu Skip to content Skip to footer

2019

Journal Article

Biomarker cruises in sepsis: who is the CAPTAIN? Discussion on “Circulating biomarkers may be unable to detect infection at the early phase of sepsis in ICU patients: the CAPTAIN prospective multicenter cohort study”

Briassoulis, George, Briassoulis, Panagiotis, Miliaraki, Marianna, Ilia, Stavroula, Parlato, Marianna, Philippart, François, Rouquette, Alexandra, Moucadel, Virginie, Cavaillon, Jean-Marc, Misset, Benoît, Combined Approach for The eArly diagnosis of INfection in sepsis (CAPTAIN) study group and Guimaraes, Fernando (2019). Biomarker cruises in sepsis: who is the CAPTAIN? Discussion on “Circulating biomarkers may be unable to detect infection at the early phase of sepsis in ICU patients: the CAPTAIN prospective multicenter cohort study”. Intensive Care Medicine, 45 (1), 132-133. doi: 10.1007/s00134-018-5451-y

Biomarker cruises in sepsis: who is the CAPTAIN? Discussion on “Circulating biomarkers may be unable to detect infection at the early phase of sepsis in ICU patients: the CAPTAIN prospective multicenter cohort study”

2019

Journal Article

Context-dependent role for T-bet in T follicular helper differentiation and germinal center function following viral infection

Sheikh, Amania A., Cooper, Lucy, Feng, Meiqi, Souza-Fonseca-Guimaraes, Fernando, Lafouresse, Fanny, Duckworth, Brigette C., Huntington, Nicholas D., Moon, James J., Pellegrini, Marc, Nutt, Stephen L., Belz, Gabrielle T., Good-Jacobson, Kim L. and Groom, Joanna R. (2019). Context-dependent role for T-bet in T follicular helper differentiation and germinal center function following viral infection. Cell Reports, 28 (7), 1758-1772.e4. doi: 10.1016/j.celrep.2019.07.034

Context-dependent role for T-bet in T follicular helper differentiation and germinal center function following viral infection

2018

Journal Article

NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease

Tye, Hazel, Yu, Chien-Hsiung, Simms, Lisa A., de Zoete, Marcel R., Kim, Man Lyang, Zakrzewski, Martha, Penington, Jocelyn S., Harapas, Cassandra R., Souza-Fonseca-Guimaraes, Fernando, Wockner, Leesa F., Preaudet, Adele, Mielke, Lisa A., Wilcox, Stephen A., Ogura, Yasunori, Corr, Sinead C., Kanojia, Komal, Kouremenos, Konstantinos A., De Souza, David P., McConville, Malcolm J., Flavell, Richard A., Gerlic, Motti, Kile, Benjamin T., Papenfuss, Anthony T., Putoczki, Tracy L., Radford-Smith, Graham L. and Masters, Seth L. (2018). NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease. Nature Communications, 9 (1) 3728, 3728. doi: 10.1038/s41467-018-06125-0

NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease

2018

Journal Article

Recipient BCL2 inhibition and NK cell ablation form part of a reduced intensity conditioning regime that improves allo-bone marrow transplantation outcomes

Jiao, Yuhao, Davis, Joanne E., Rautela, Jai, Carrington, Emma M., Ludford-Menting, Mandy J., Goh, Wilford, Delconte, Rebecca B., Souza-Fonseca-Guimaraes, Fernando, Koldej, Rachel, Gray, Daniel, Huang, David, Kile, Ben T., Lew, Andrew M., Ritchie, David S. and Huntington, Nicholas D. (2018). Recipient BCL2 inhibition and NK cell ablation form part of a reduced intensity conditioning regime that improves allo-bone marrow transplantation outcomes. Cell Death & Differentiation, 26 (8), 1516-1530. doi: 10.1038/s41418-018-0228-y

Recipient BCL2 inhibition and NK cell ablation form part of a reduced intensity conditioning regime that improves allo-bone marrow transplantation outcomes

2018

Journal Article

GM-CSF quantity has a selective effect on granulocytic vs. monocytic myeloid development and function

Sun, Li, Rautela, Jai, Delconte, Rebecca B., Souza-Fonseca-Guimaraes, Fernando, Carrington, Emma M., Schenk, Robyn L., Herold, Marco J., Huntington, Nicholas D., Lew, Andrew M., Xu, Yuekang and Zhan, Yifan (2018). GM-CSF quantity has a selective effect on granulocytic vs. monocytic myeloid development and function. Frontiers in Immunology, 9 1922. doi: 10.3389/fimmu.2018.01922

GM-CSF quantity has a selective effect on granulocytic vs. monocytic myeloid development and function

2018

Journal Article

Circulating biomarkers may be unable to detect infection at the early phase of sepsis in ICU patients: the CAPTAIN prospective multicenter cohort study

Parlato, Marianna, Philippart, François, Rouquette, Alexandra, Moucadel, Virginie, Puchois, Virginie, Blein, Sophie, Bedos, Jean-Pierre, Diehl, Jean-Luc, Hamzaoui, Olfa, Annane, Djillali, Journois, Didier, Ben Boutieb, Myriam, Estève, Laurent, Fitting, Catherine, Treluyer, Jean-Marc, Pachot, Alexandre, Adib-Conquy, Minou, Cavaillon, Jean-Marc, Misset, Benoît, Jacqmin, Sébastien, Lagrange, Alix, de Pinot de Villechenon, Gabrielle, Aissaoui, Nadia, Guerot, Emmanuel, Venot, Marion, Prat, Dominique, Sztrymf, Benjamin, Maxime, Virginie, Polito, Andrea ... Souza-Fonseca-Guimaraes, Fernando (2018). Circulating biomarkers may be unable to detect infection at the early phase of sepsis in ICU patients: the CAPTAIN prospective multicenter cohort study. Intensive Care Medicine, 44 (7), 1061-1070. doi: 10.1007/s00134-018-5228-3

Circulating biomarkers may be unable to detect infection at the early phase of sepsis in ICU patients: the CAPTAIN prospective multicenter cohort study

2018

Journal Article

Molecular insight into targeting the NK cell immune response to cancer

Rautela, Jai, Souza-Fonseca-Guimaraes, Fernando, Hediyeh-Zadeh, Soroor, Delconte, Rebecca B., Davis, Melissa J. and Huntington, Nicholas D. (2018). Molecular insight into targeting the NK cell immune response to cancer. Immunology and Cell Biology, 96 (5), 477-484. doi: 10.1111/imcb.12045

Molecular insight into targeting the NK cell immune response to cancer

2018

Journal Article

A2AR adenosine signaling suppresses natural killer cell maturation in the tumor microenvironment

Young, Arabella, Ngiow, Shin Foong, Gao, Yulong, Patch, Ann-Marie, Barkauskas, Deborah S., Messaoudene, Meriem, Lin, Gene, Coudert, Jerome D., Stannard, Kimberley A., Zitvogel, Laurence, Degli-Esposti, Mariapia A., Vivier, Eric, Waddell, Nicola, Linden, Joel, Huntington, Nicholas D., Souza-Fonseca-Guimaraes, Fernando and Smyth, Mark J. (2018). A2AR adenosine signaling suppresses natural killer cell maturation in the tumor microenvironment. Cancer Research, 78 (4), 1003-1016. doi: 10.1158/0008-5472.CAN-17-2826

A2AR adenosine signaling suppresses natural killer cell maturation in the tumor microenvironment

2018

Journal Article

Rapid loss of group 1 innate lymphoid cells during blood stage Plasmodium infection

Ng, Susanna S., Souza-Fonseca-Guimaraes, Fernando, Rivera, Fabian de Labastida, Amante, Fiona H., Kumar, Rajiv, Gao, Yulong, Sheel, Meru, Beattie, Lynette, de Oca, Marcela Montes, Guillerey, Camille, Edwards, Chelsea L., Faleiro, Rebecca J., Frame, Teija, Bunn, Patrick T., Vivier, Eric, Godfrey, Dale I., Pellicci, Daniel G., Lopez, J. Alejandro, Andrews, Katherine T., Huntington, Nicholas D., Smyth, Mark J., McCarthy, James and Engwerda, Christian R. (2018). Rapid loss of group 1 innate lymphoid cells during blood stage Plasmodium infection. Clinical and Translational Immunology, 7 (1) e1003, e1003. doi: 10.1002/cti2.1003

Rapid loss of group 1 innate lymphoid cells during blood stage Plasmodium infection

2018

Journal Article

A new checkpoint for Natural Killer cell activation

Souza-Fonseca-Guimaraes, Fernando and Huntington, Nicholas D. (2018). A new checkpoint for Natural Killer cell activation. Immunology and Cell Biology, 96 (1), 5-7. doi: 10.1111/imcb.1027

A new checkpoint for Natural Killer cell activation

2018

Conference Publication

Oncogenic-Drivers Dictate Immune Responses to Control Disease Progression in Acute Myeloid Leukaemia

Austin, Rebecca, Bywater, Megan, Straube, Jasmin, Cooper, Leanne T., Headlam, Madeleine, Dave, Keyur, Braun, Matthias, Bald, Tobias, Guimaraes, Fernando, Jacquelin, Sebastien, Witkowski, Matthew, Aifantis, Iannis, Hill, Geoffrey R., Smyth, Mark J. and Lane, Steven W. (2018). Oncogenic-Drivers Dictate Immune Responses to Control Disease Progression in Acute Myeloid Leukaemia. 60th Annual Meeting of the American-Society-of-Hematology (ASH), San Diego, CA, United States, 1-4 December 2018. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood-2018-99-112009

Oncogenic-Drivers Dictate Immune Responses to Control Disease Progression in Acute Myeloid Leukaemia

2017

Journal Article

Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cells

Gao, Yulong, Souza-Fonseca-Guimaraes, Fernando, Bald, Tobias, Ng, Susanna S., Young, Arabella, Ngiow, Shin Foong, Rautela, Jai, Straube, Jasmin, Waddell, Nic, Blake, Stephen J., Yan, Juming, Bartholin, Laurent, Lee, Jason S., Vivier, Eric, Takeda, Kazuyoshi, Messaoudene, Meriem, Zitvogel-, Laurence, Teng, Michele W. L., Belz, Gabrielle T., Engwerda, Christian R., Huntington, Nicholas D., Nakamura, Kyohei, Hoelzel, Michael and Smyth, Mark J. (2017). Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cells. Nature Immunology, 18 (9), 1004-1015. doi: 10.1038/ni.3800

Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cells

2017

Journal Article

NK cell heparanase controls tumor invasion and immune surveillance

Putz, Eva M., Mayfosh, Alyce J., Kos, Kevin, Barkauskas, Deborah S., Nakamura, Kyohei, Town, Liam, Goodall, Katharine J., Yee, Dean Y., Poon, Ivan K. H., Baschuk, Nikola, Souza-Fonseca-Guimaraes, Fernando, Hulett, Mark D. and Smyth, Mark J. (2017). NK cell heparanase controls tumor invasion and immune surveillance. Journal of Clinical Investigation, 127 (7), 2777-2788. doi: 10.1172/JCI92958

NK cell heparanase controls tumor invasion and immune surveillance

2017

Journal Article

Natural killer cell assessment in peripheral circulation and bronchoalveolar lavage fluid of patients with severe sepsis: a case control study

Souza-Fonseca-Guimaraes, Paulo, Guimaraes, Fernando, de Souza-Araujo, Caroline Natânia, Leite, Lidiane Maria Boldrini, Senegaglia, Alexandra Cristina, Nishiyama, Anita and Souza-Fonseca-Guimaraes, Fernando (2017). Natural killer cell assessment in peripheral circulation and bronchoalveolar lavage fluid of patients with severe sepsis: a case control study. International Journal of Molecular Sciences, 18 (3) 616, 616. doi: 10.3390/ijms18030616

Natural killer cell assessment in peripheral circulation and bronchoalveolar lavage fluid of patients with severe sepsis: a case control study

2017

Journal Article

Single-cell RNA-seq and computational analysis using temporal mixture modeling resolves TH1/TFHfate bifurcation in malaria

Lönnberg, Tapio, Svensson, Valentine, James, Kylie R., Fernandez-Ruiz, Daniel, Sebina, Ismail, Montandon, Ruddy, Soon, Megan S. F., Fogg, Lily G., Nair, Arya Sheela, Liligeto, Urijah N., Stubbington, Michael J. T., Ly, Lam-Ha, Bagger, Frederik Otzen, Zwiessele, Max, Lawrence, Neil D., Souza-Fonseca-Guimaraes, Fernando, Bunn, Patrick T., Engwerda, Christian R., Heath, William R., Billker, Oliver, Stegle, Oliver, Haque, Ashraful and Teichmann, Sarah A. (2017). Single-cell RNA-seq and computational analysis using temporal mixture modeling resolves TH1/TFHfate bifurcation in malaria. Science Immunology, 2 (9) eaal2192, eaal2192. doi: 10.1126/sciimmunol.aal2192

Single-cell RNA-seq and computational analysis using temporal mixture modeling resolves TH1/TFHfate bifurcation in malaria

2017

Journal Article

Cell cycle progression dictates the requirement for BCL2 in natural killer cell survival

Viant, Charlotte, Guia, Sophie, Hennessy, Robert J., Rautela, Jai, Pham, Kim, Bernat, Claire, Goh, Wilford, Jiao, Yuhao, Delconte, Rebecca, Roger, Michael, Simon, Vanina, Souza-Fonseca-Guimaraes, Fernando, Grabow, Stephanie, Belz, Gabrielle T., Kile, Benjamin T., Strasser, Andreas, Gray, Daniel, Hodgkin, Phillip D., Beutler, Bruce, Vivier, Eric, Ugolini, Sophie and Huntington, Nicholas D. (2017). Cell cycle progression dictates the requirement for BCL2 in natural killer cell survival. Journal of Experimental Medicine, 214 (2), 491-510. doi: 10.1084/jem.20160869

Cell cycle progression dictates the requirement for BCL2 in natural killer cell survival

2017

Journal Article

GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity

Bunting, Mark D., Varelias, Antiopi, Souza-Fonseca-Guimaraes, Fernando, Schuster, Iona S., Lineburg, Katie E., Kuns, Rachel D., Fleming, Peter, Locke, Kelly R., Huntington, Nicholas D., Blazar, Bruce R., Lane, Steven W., Tey, Siok-Keen, MacDonald, Kelli P. A., Smyth, Mark J., Degli-Esposti, Mariapia A. and Hill, Geoffrey R. (2017). GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity. Blood, 129 (5), 630-642. doi: 10.1182/blood-2016-08-734020

GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity

2016

Journal Article

IFNAR1-signalling obstructs ICOS-mediated humoral immunity during non-lethal blood-stage Plasmodium infection

Sebina, Ismail, James, Kylie R., Soon, Megan S. F., Fogg, Lily G., Best, Shannon E., Labastida Rivera, Fabian de, Montes de Oca, Marcela, Amante, Fiona H., Thomas, Bryce S., Beattie, Lynette, Souza-Fonseca-Guimaraes, Fernando, Smyth, Mark J., Hertzog, Paul J., Hill, Geoffrey R., Hutloff, Andreas, Engwerda, Christian R. and Haque, Ashraful (2016). IFNAR1-signalling obstructs ICOS-mediated humoral immunity during non-lethal blood-stage Plasmodium infection. PLoS Pathogens, 12 (11) e1005999, e1005999. doi: 10.1371/journal.ppat.1005999

IFNAR1-signalling obstructs ICOS-mediated humoral immunity during non-lethal blood-stage Plasmodium infection

2016

Journal Article

Autophagy-dependent regulatory T cells are critical for the control of graft-versus-host disease

Le Texier, Laetitia, Lineburg, Katie E., Cao, Benjamin, McDonald-Hyman, Cameron, Leveque-El Mouttie, Lucie, Nicholls, Jemma, Melino, Michelle, Nalkurthi, Blessy C., Alexander, Kylie A., Teal, Bianca, Blake, Stephen J., Souza-Fonseca-Guimaraes, Fernando, Engwerda, Christian R., Kuns, Rachel D., Lane, Steven W., Teng, Michele, Teh, Charis, Gray, Daniel, Clouston, Andrew D., Nilsson, Susan K., Blazar, Bruce R., Hill, Geoffrey R. and MacDonald, Kelli P. A. (2016). Autophagy-dependent regulatory T cells are critical for the control of graft-versus-host disease. JCI Insight, 1 (15) e86850, e86850. doi: 10.1172/jci.insight.86850

Autophagy-dependent regulatory T cells are critical for the control of graft-versus-host disease

2016

Journal Article

Anti-CD137 enhances anti-CD20 therapy of systemic B-cell lymphoma with altered immune homeostasis but negligible toxicity

Souza-Fonseca-Guimaraes, Fernando, Blake, Stephen J., Makkouk, Amani, Chester, Cariad, Kohrt, Holbrook E. and Smyth, Mark J. (2016). Anti-CD137 enhances anti-CD20 therapy of systemic B-cell lymphoma with altered immune homeostasis but negligible toxicity. OncoImmunology, 5 (7) e1192740, e1192740. doi: 10.1080/2162402X.2016.1192740

Anti-CD137 enhances anti-CD20 therapy of systemic B-cell lymphoma with altered immune homeostasis but negligible toxicity