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2020

Journal Article

Harnessing natural killer immunity in metastatic SCLC

Best, Sarah A., Hess, Jonas B., Souza-Fonseca-Guimaraes, Fernando, Cursons, Joseph, Kersbergen, Ariena, Dong, Xueyi, Rautela, Jai, Hyslop, Stephanie R., Ritchie, Matthew E., Davis, Melissa J., Leong, Tracy L., Irving, Louis, Steinfort, Daniel, Huntington, Nicholas D. and Sutherland, Kate D. (2020). Harnessing natural killer immunity in metastatic SCLC. Journal of Thoracic Oncology, 15 (9), 1507-1521. doi: 10.1016/j.jtho.2020.05.008

Harnessing natural killer immunity in metastatic SCLC

2020

Journal Article

Erratum:NK cell-derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS (Journal of Experimental Medicine (2020) 217:5 DOI: 10.1084/jem.20191421)

Louis, Cynthia, Souza-Fonseca-Guimaraes, Fernando, Yang, Yuyan, D'Silva, Damian, Kratina, Tobias, Dagley, Laura, Hediyeh-Zadeh, Soroor, Rautela, Jai, Masters, Seth Lucian, Davis, Melissa J., Babon, Jeffrey J., Ciric, Bogoljub, Vivier, Eric, Alexander, Warren S., Huntington, Nicholas D. and Wicks, Ian P. (2020). Erratum:NK cell-derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS (Journal of Experimental Medicine (2020) 217:5 DOI: 10.1084/jem.20191421). Journal of Experimental Medicine, 217 (5) e2019142103192020c. doi: 10.1084/jem.2019142103192020c

Erratum:NK cell-derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS (Journal of Experimental Medicine (2020) 217:5 DOI: 10.1084/jem.20191421)

2020

Conference Publication

Awakening Natural Killer (NK) cells for cancer therapy: the cure can be inside us

Souza-Fonseca-Guimaraes, Fernando (2020). Awakening Natural Killer (NK) cells for cancer therapy: the cure can be inside us. UQ Faculty of Medicine - Research Expo, Virtual, 18 March 2020.

Awakening Natural Killer (NK) cells for cancer therapy: the cure can be inside us

2020

Journal Article

Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies

Chew, Hui Yi, De Lima, Priscila O., Gonzalez Cruz, Jazmina L., Banushi, Blerida, Echejoh, Godwins, Hu, Lingbo, Joseph, Shannon R., Lum, Benedict, Rae, James, O'Donnell, Jake S., Merida de Long, Lilia, Okano, Satomi, King, Brigid, Barry, Rachael, Moi, Davide, Mazzieri, Roberta, Thomas, Ranjeny, Souza-Fonseca-Guimaraes, Fernando, Foote, Matthew, McCluskey, Adam, Robinson, Phillip J., Frazer, Ian H., Saunders, Nicholas A., Parton, Robert G., Dolcetti, Riccardo, Cuff, Katharine, Martin, Jennifer H., Panizza, Benedict, Walpole, Euan ... Simpson, Fiona (2020). Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies. Cell, 180 (5), 895-914.e27. doi: 10.1016/j.cell.2020.02.019

Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies

2020

Journal Article

NK cell–derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS

Louis, Cynthia, Souza-Fonseca-Guimaraes, Fernando, Yang, Yuyan, D’Silva, Damian, Kratina, Tobias, Dagley, Laura, Hediyeh-Zadeh, Soroor, Rautela, Jai, Masters, Seth Lucian, Davis, Melissa J., Babon, Jeffrey J., Ciric, Bogoljub, Vivier, Eric, Alexander, Warren S., Huntington, Nicholas D. and Wicks, Ian P. (2020). NK cell–derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS. Journal of Experimental Medicine, 217 (5) e20191421. doi: 10.1084/jem.20191421

NK cell–derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS

2020

Journal Article

NK cell priming from endogenous homeostatic signals is modulated by CIS

Delconte, Rebecca B., Guittard, Geoffrey, Goh, Wilford, Hediyeh-Zadeh, Soroor, Hennessy, Robert J., Rautela, Jai, Davis, Melissa J., Souza-Fonseca-Guimaraes, Fernando, Nunes, Jacques A. and Huntington, Nicholas D. (2020). NK cell priming from endogenous homeostatic signals is modulated by CIS. Frontiers in Immunology, 11 75, 75. doi: 10.3389/fimmu.2020.00075

NK cell priming from endogenous homeostatic signals is modulated by CIS

2020

Journal Article

Tumor microenvironment-associated extracellular matrix components regulate NK cell function

Rossi, Gustavo Rodrigues, Trindade, Edvaldo S. and Souza-Fonseca-Guimaraes, Fernando (2020). Tumor microenvironment-associated extracellular matrix components regulate NK cell function. Frontiers in Immunology, 11 73, 73. doi: 10.3389/fimmu.2020.00073

Tumor microenvironment-associated extracellular matrix components regulate NK cell function

2019

Conference Publication

Therapeutic blockade of TGF-b superfamily members improves NK cell function and anti-tumour immunity

Souza-Fonseca-Guimaraes, Fernando (2019). Therapeutic blockade of TGF-b superfamily members improves NK cell function and anti-tumour immunity. Annual Scientific Meeting of The Australian and New Zealand Society for Immunology, Adelaide, SA, Australia, 8-12 December 2019.

Therapeutic blockade of TGF-b superfamily members improves NK cell function and anti-tumour immunity

2019

Conference Publication

Therapeutic blockade of TGF-b improves NK cell function and anti-tumour immunity

Souza-Fonseca-Guimaraes, Fernando (2019). Therapeutic blockade of TGF-b improves NK cell function and anti-tumour immunity. Keystone Symposia on Cancer Evolution and Combinatorial Cancer, Banff, AB, Canada, 2-5 December 2019.

Therapeutic blockade of TGF-b improves NK cell function and anti-tumour immunity

2019

Conference Publication

Emergence of natural killer cells as a major target in immunotherapy

Souza-Fonseca-Guimaraes, Fernando (2019). Emergence of natural killer cells as a major target in immunotherapy. Brisbane Cancer Conference Annual Meeting, Brisbane, QLD, Australia, 28-29 November 2019.

Emergence of natural killer cells as a major target in immunotherapy

2019

Journal Article

Generation of novel Id2 and E2-2, E2A and HEB antibodies reveals novel Id2 binding partners and species-specific expression of E-proteins in NK cells

Rautela, Jai, Dagley, Laura F., Kratina, Tobias, Anthony, Angaleena, Goh, Wilford, Surgenor, Elliot, Delconte, Rebecca B., Webb, Andrew I., Elwood, Ngaire, Groom, Joanna R., Souza-Fonseca-Guimaraes, Fernando, Corcoran, Lynn and Huntington, Nicholas D. (2019). Generation of novel Id2 and E2-2, E2A and HEB antibodies reveals novel Id2 binding partners and species-specific expression of E-proteins in NK cells. Molecular Immunology, 115, 56-63. doi: 10.1016/j.molimm.2018.08.017

Generation of novel Id2 and E2-2, E2A and HEB antibodies reveals novel Id2 binding partners and species-specific expression of E-proteins in NK cells

2019

Journal Article

Therapeutic blockade of activin-A improves NK cell function and antitumor immunity

Rautela, Jai, Dagley, Laura F., de Oliveira, Carolina C., Schuster, Iona S., Hediyeh-Zadeh, Soroor, Delconte, Rebecca B., Cursons, Joseph, Hennessy, Robert, Hutchinson, Dana S., Harrison, Craig, Kita, Badia, Vivier, Eric, Webb, Andrew I., Degli-Esposti, Mariapia A., Davis, Melissa J., Huntington, Nicholas D. and Souza-Fonseca-Guimaraes, Fernando (2019). Therapeutic blockade of activin-A improves NK cell function and antitumor immunity. Science Signaling, 12 (596) aat7527, eaat7527. doi: 10.1126/scisignal.aat7527

Therapeutic blockade of activin-A improves NK cell function and antitumor immunity

2019

Conference Publication

The emergence of natural killer cells as a major target in immunotherapy

Souza-Fonseca-Guimaraes, Fernando (2019). The emergence of natural killer cells as a major target in immunotherapy. Araucaria Symposium 2019, Curitiba, PR, Brazil, 15-17 June 2019.

The emergence of natural killer cells as a major target in immunotherapy

2019

Journal Article

A gene signature predicting natural killer cell infiltration and improved survival in melanoma patients

Cursons, Joseph, Souza-Fonseca-Guimaraes, Fernando, Foroutan, Momeneh, Anderson, Ashley, Hollande, Frédéric, Hediyeh-Zadeh, Soroor, Behren, Andreas, Huntington, Nicholas D. and Davis, Melissa J. (2019). A gene signature predicting natural killer cell infiltration and improved survival in melanoma patients. Cancer Immunology Research, 7 (7), 1162-1174. doi: 10.1158/2326-6066.cir-18-0500

A gene signature predicting natural killer cell infiltration and improved survival in melanoma patients

2019

Journal Article

Loss-of-Function in SMAD4 Might Not Be Critical for Human Natural Killer Cell Responsiveness to TGF-β

Healy, Lachlan P., Rossi, Gustavo R., Rautela, Jai, Slade, Charlotte A., Huntington, Nicholas D., Winship, Ingrid M. and Souza-Fonseca-Guimaraes, Fernando (2019). Loss-of-Function in SMAD4 Might Not Be Critical for Human Natural Killer Cell Responsiveness to TGF-β. Frontiers in Immunology, 10 (MAY) 904. doi: 10.3389/fimmu.2019.00904

Loss-of-Function in SMAD4 Might Not Be Critical for Human Natural Killer Cell Responsiveness to TGF-β

2019

Journal Article

A novel immunogenic mouse model of melanoma for the preclinical assessment of combination targeted and immune-based therapy

Lelliott, Emily J., Cullinane, Carleen, Martin, Claire A., Walker, Rachael, Ramsbottom, Kelly M., Souza-Fonseca-Guimaraes, Fernando, Abuhammad, Shatha, Michie, Jessica, Kirby, Laura, Young, Richard J., Slater, Alison, Lau, Peter, Meeth, Katrina, Oliaro, Jane, Haynes, Nicole, McArthur, Grant A. and Sheppard, Karen E. (2019). A novel immunogenic mouse model of melanoma for the preclinical assessment of combination targeted and immune-based therapy. Scientific Reports, 9 (1) 1225. doi: 10.1038/s41598-018-37883-y

A novel immunogenic mouse model of melanoma for the preclinical assessment of combination targeted and immune-based therapy

2019

Journal Article

The Emergence of Natural Killer Cells as a Major Target in Cancer Immunotherapy

Souza-Fonseca-Guimaraes, Fernando, Cursons, Joseph and Huntington, Nicholas D. (2019). The Emergence of Natural Killer Cells as a Major Target in Cancer Immunotherapy. Trends in Immunology, 40 (2), 142-158. doi: 10.1016/j.it.2018.12.003

The Emergence of Natural Killer Cells as a Major Target in Cancer Immunotherapy

2019

Journal Article

Context-dependent role for T-bet in T follicular helper differentiation and germinal center function following viral infection

Sheikh, Amania A., Cooper, Lucy, Feng, Meiqi, Souza-Fonseca-Guimaraes, Fernando, Lafouresse, Fanny, Duckworth, Brigette C., Huntington, Nicholas D., Moon, James J., Pellegrini, Marc, Nutt, Stephen L., Belz, Gabrielle T., Good-Jacobson, Kim L. and Groom, Joanna R. (2019). Context-dependent role for T-bet in T follicular helper differentiation and germinal center function following viral infection. Cell Reports, 28 (7), 1758-1772.e4. doi: 10.1016/j.celrep.2019.07.034

Context-dependent role for T-bet in T follicular helper differentiation and germinal center function following viral infection

2019

Journal Article

Biomarker cruises in sepsis: who is the CAPTAIN? Discussion on “Circulating biomarkers may be unable to detect infection at the early phase of sepsis in ICU patients: the CAPTAIN prospective multicenter cohort study”

Briassoulis, George, Briassoulis, Panagiotis, Miliaraki, Marianna, Ilia, Stavroula, Parlato, Marianna, Philippart, François, Rouquette, Alexandra, Moucadel, Virginie, Cavaillon, Jean-Marc, Misset, Benoît, Combined Approach for The eArly diagnosis of INfection in sepsis (CAPTAIN) study group and Guimaraes, Fernando (2019). Biomarker cruises in sepsis: who is the CAPTAIN? Discussion on “Circulating biomarkers may be unable to detect infection at the early phase of sepsis in ICU patients: the CAPTAIN prospective multicenter cohort study”. Intensive Care Medicine, 45 (1), 132-133. doi: 10.1007/s00134-018-5451-y

Biomarker cruises in sepsis: who is the CAPTAIN? Discussion on “Circulating biomarkers may be unable to detect infection at the early phase of sepsis in ICU patients: the CAPTAIN prospective multicenter cohort study”

2018

Journal Article

NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease

Tye, Hazel, Yu, Chien-Hsiung, Simms, Lisa A., de Zoete, Marcel R., Kim, Man Lyang, Zakrzewski, Martha, Penington, Jocelyn S., Harapas, Cassandra R., Souza-Fonseca-Guimaraes, Fernando, Wockner, Leesa F., Preaudet, Adele, Mielke, Lisa A., Wilcox, Stephen A., Ogura, Yasunori, Corr, Sinead C., Kanojia, Komal, Kouremenos, Konstantinos A., De Souza, David P., McConville, Malcolm J., Flavell, Richard A., Gerlic, Motti, Kile, Benjamin T., Papenfuss, Anthony T., Putoczki, Tracy L., Radford-Smith, Graham L. and Masters, Seth L. (2018). NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease. Nature Communications, 9 (1) 3728, 3728. doi: 10.1038/s41467-018-06125-0

NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease