|
2025 Journal Article Cancer-derived extracellular vesicles in natural killer cell immune evasion: molecular mechanisms and therapeutic insightsColeborn, Elaina, Ghebosu, Raluca, Wolfram, Joy and Souza-Fonseca-Guimaraes, Fernando (2025). Cancer-derived extracellular vesicles in natural killer cell immune evasion: molecular mechanisms and therapeutic insights. Molecular Therapy, 33 (9), 4113-4129. doi: 10.1016/j.ymthe.2025.05.038 |
|
2025 Journal Article Coordinated development of immune cell populations in vascularized skin organoids from human induced pluripotent stem cellsMostina, Mitchell, Sun, Jane, Sim, Seen Ling, Ahmed, Imaan A., Souza-Fonesca-Guimaraes, Fernando, Wolvetang, Ernst J., Brown, Jason, Kumari, Snehlata, Khosrotehrani, Kiarash and Shafiee, Abbas (2025). Coordinated development of immune cell populations in vascularized skin organoids from human induced pluripotent stem cells. Advanced Healthcare Materials e02108, e02108. doi: 10.1002/adhm.202502108 |
|
2025 Journal Article Lymph-node-derived stem-like but not tumor-tissue-resident CD8+ T cells fuel anticancer immunityWijesinghe, Sharanya K. M., Rausch, Lisa, Gabriel, Sarah S., Galletti, Giovanni, De Luca, Marco, Qin, Lei, Wen, Lifen, Tsui, Carlson, Man, Kevin, Heyden, Leonie, Mason, Teisha, Newland, Lewis D., Kueh, Andrew, Liao, Yang, Chisanga, David, Swatler, Julian, Voulaz, Emanuele, Marulli, Giuseppe, Errico, Valentina, Losurdo, Agnese, Rossi, Gustavo R., Souza-Fonseca-Guimaraes, Fernando, Huntington, Nicholas D., Gebhardt, Thomas, Utzschneider, Daniel T., Herold, Marco J., Shi, Wei, Schroeder, Jan, Lugli, Enrico and Kallies, Axel (2025). Lymph-node-derived stem-like but not tumor-tissue-resident CD8+ T cells fuel anticancer immunity. Nature Immunology, 26 (8), 1367-1383. doi: 10.1038/s41590-025-02219-2 |
|
2025 Journal Article Tumor site-directed A1R expression enhances CAR T cell function and improves efficacy against solid tumorsSek, Kevin, Chen, Amanda X. Y., Cole, Thomas, Armitage, Jesse D., Tong, Junming, Yap, Kah Min, Munoz, Isabelle, Dunbar, Phoebe A., Wu, Shiyi, van Elsas, Marit J., Hidajat, Olivia, Scheffler, Christina, Giuffrida, Lauren, Henderson, Melissa A., Meyran, Deborah, Souza-Fonseca-Guimaraes, Fernando, Nguyen, Dat, Huang, Yu-Kuan, de Menezes, Maria N., Derrick, Emily B., Chan, Cheok Weng, Todd, Kirsten L., Chan, Jack D., Li, Jasmine, Lai, Junyun, Petley, Emma V., Mardiana, Sherly, Bosco, Anthony, Waithman, Jason ... Beavis, Paul A. (2025). Tumor site-directed A1R expression enhances CAR T cell function and improves efficacy against solid tumors. Nature Communications, 16 (1) 6123, 1-17. doi: 10.1038/s41467-025-59021-9 |
|
2025 Journal Article Highlights of 2024. Broadening anti‐cancer immunotherapy modalities with antibody–drug conjugates: emerging insights from clinical studiesJose, Jiya, Hooper, John D. and Souza‐Fonseca‐Guimaraes, Fernando (2025). Highlights of 2024. Broadening anti‐cancer immunotherapy modalities with antibody–drug conjugates: emerging insights from clinical studies. Immunology and Cell Biology, 103 (6), 530-534. doi: 10.1111/imcb.70017 |
|
2025 Journal Article Highlights of 2024: unleashing the power of NK cells—cancer's worst nightmareBourel, Capucine, Souza‐Fonseca‐Guimaraes, Fernando and Lesage, Sylvie (2025). Highlights of 2024: unleashing the power of NK cells—cancer's worst nightmare. Immunology & Cell Biology, 103 (6), 526-529. doi: 10.1111/imcb.70037 |
|
2025 Journal Article Highlights of 2024: Cytokines and ligands modulating NK cell effector functionsShajan, Aneena Mary, Alim, Louisa and Souza‐Fonseca‐Guimaraes, Fernando (2025). Highlights of 2024: Cytokines and ligands modulating NK cell effector functions. Immunology and Cell Biology, 103 (6), 522-525. doi: 10.1111/imcb.70014 |
|
2025 Journal Article Enhancement of anti-sarcoma immunity by NK cells engineered with mRNA for expression of a EphA2-targeted CARLam, Pui Yeng, Omer, Natacha, Wong, Josh K. M., Tu, Cui, Alim, Louisa, Rossi, Gustavo R., Victorova, Maria, Tompkins, Hannah, Lin, Cheng-Yu, Mehdi, Ahmed M., Choo, Amos, Elliott, Melissa R., Coleborn, Elaina, Sun, Jane, Mercer, Timothy, Vittorio, Orazio, Dobson, Lachlan J., Mclellan, Alexander D., Brooks, Andrew, Tuong, Zewen Kelvin, Cheetham, Seth W., Nicholls, Wayne and Souza-Fonseca-Guimaraes, Fernando (2025). Enhancement of anti-sarcoma immunity by NK cells engineered with mRNA for expression of a EphA2-targeted CAR. Clinical and Translational Medicine, 15 (1) e70140, 1-21. doi: 10.1002/ctm2.70140 |
|
2025 Journal Article Engineered iPSC‐derived natural killer cells: recent innovations in translational innate anti‐cancer immunotherapySun, Jane, Elliott, Melissa and Souza‐Fonseca‐Guimaraes, Fernando (2025). Engineered iPSC‐derived natural killer cells: recent innovations in translational innate anti‐cancer immunotherapy. Clinical and Translational Immunology, 14 (7) e70045, 1-15. doi: 10.1002/cti2.70045 |
|
2024 Journal Article Dichotomous outcomes of TNFR1 and TNFR2 signaling in NK cell-mediated immune responses during inflammationMcCulloch, Timothy R., Rossi, Gustavo R., Alim, Louisa, Lam, Pui Yeng, Wong, Joshua K. M., Coleborn, Elaina, Kumari, Snehlata, Keane, Colm, Kueh, Andrew J., Herold, Marco J., Wilhelm, Christoph, Knolle, Percy A., Kane, Lawrence, Wells, Timothy J. and Souza-Fonseca-Guimaraes, Fernando (2024). Dichotomous outcomes of TNFR1 and TNFR2 signaling in NK cell-mediated immune responses during inflammation. Nature Communications, 15 (1) 9871, 1-16. doi: 10.1038/s41467-024-54232-y |
|
2024 Journal Article A scalable, spin‐free approach to generate enhanced induced pluripotent stem cell–derived natural killer cells for cancer immunotherapyRossi, Gustavo R., Sun, Jane, Lin, Cheng‐Yu, Wong, Joshua K.M., Alim, Louisa, Lam, Pui Yeng, Khosrotehrani, Kiarash, Wolvetang, Ernst, Cheetham, Seth W., Derrick, Emily B., Amoako, Akwasi, Lehner, Christoph, Brooks, Andrew J., Beavis, Paul A. and Souza‐Fonseca‐Guimaraes, Fernando (2024). A scalable, spin‐free approach to generate enhanced induced pluripotent stem cell–derived natural killer cells for cancer immunotherapy. Immunology & Cell Biology, 102 (10), 1-11. doi: 10.1111/imcb.12820 |
|
2024 Journal Article The current molecular and cellular landscape of chronic obstructive pulmonary disease (COPD): a review of therapies and efforts towards personalized treatmentFarrell, Luke A., O’Rourke, Matthew B., Padula, Matthew P., Souza-Fonseca-Guimaraes, Fernando, Caramori, Gaetano, Wark, Peter A. B., Dharmage, Shymali C. and Hansbro, Phillip M. (2024). The current molecular and cellular landscape of chronic obstructive pulmonary disease (COPD): a review of therapies and efforts towards personalized treatment. Proteomes, 12 (3) 23, 1-31. doi: 10.3390/proteomes12030023 |
|
2024 Journal Article Highlight of 2023: Unlocking the therapeutic potential of natural killer cells—advances in adaptive functions, cellular engineering and immunotherapyLam, Pui Yeng and Souza‐Fonseca‐Guimaraes, Fernando (2024). Highlight of 2023: Unlocking the therapeutic potential of natural killer cells—advances in adaptive functions, cellular engineering and immunotherapy. Immunology and Cell Biology, 102 (6), 444-447. doi: 10.1111/imcb.12769 |
|
2024 Journal Article The immune checkpoint TIGIT is upregulated on T cells during bacterial infection and is a potential target for immunotherapyMcCulloch, Timothy R., Rossi, Gustavo R., Miranda‐Hernandez, Socorro, Valencia‐Hernandez, Ana Maria, Alim, Louisa, Belle, Clemence J., Krause, Andrew, Zacchi, Lucia F., Lam, Pui Yeng, Nakamura, Kyohei, Kupz, Andreas, Wells, Timothy J. and Souza‐Fonseca‐Guimaraes, Fernando (2024). The immune checkpoint TIGIT is upregulated on T cells during bacterial infection and is a potential target for immunotherapy. Immunology and Cell Biology, 102 (8), 721-733. doi: 10.1111/imcb.12794 |
|
2024 Journal Article TGF-β signalling limits effector function capacity of NK cell anti-tumour immunity in human bladder cancerWong, Joshua K. M., McCulloch, Timothy R., Alim, Louisa, Omer, Natacha, Mehdi, Ahmed M., Tuong, Zewen Kelvin, Bonfim-Melo, Alexis, Chung, Eric, Nicol, Alice, Simpson, Fiona, Rhee, Handoo, Rossi, Gustavo Rodrigues and Souza-Fonseca-Guimaraes, Fernando (2024). TGF-β signalling limits effector function capacity of NK cell anti-tumour immunity in human bladder cancer. EBioMedicine, 104 105176, 105176. doi: 10.1016/j.ebiom.2024.105176 |
|
2024 Journal Article In situ single-cell profiling sheds light on IFI27 localisation during SARS-CoV-2 infectionTan, Chin Wee, Chen, Jinjin, Liu, Ning, Bhuva, Dharmesh D., Blick, Tony, Monkman, James, Cooper, Caroline, Kharbanda, Malvika, Feher, Kristen, Phipson, Belinda, Killingbeck, Emily E., Pan, Liuliu, Kim, Youngmi, Liang, Yan, Nam, Andy, Leon, Michael, Souza-Fonseca-Guimaraes, Paulo, Nagashima, Seigo, Camargo Martins, Ana Paula, Machado-Souza, Cleber, de Noronha, Lucia, Tang, Benjamin, Short, Kirsty, Fraser, John, Belz, Gabrielle T., Souza-Fonseca-Guimaraes, Fernando, Kulasinghe, Arutha and Davis, Melissa J. (2024). In situ single-cell profiling sheds light on IFI27 localisation during SARS-CoV-2 infection. eBioMedicine, 101 105016, 1-4. doi: 10.1016/j.ebiom.2024.105016 |
|
2024 Journal Article Minimal information for studies of extracellular vesicles (MISEV2023): from basic to advanced approaches: Position paperWelsh, Joshua A., Goberdhan, Deborah C. I., O'Driscoll, Lorraine, Buzas, Edit I., Blenkiron, Cherie, Bussolati, Benedetta, Cai, Houjian, Di Vizio, Dolores, Driedonks, Tom A. P., Erdbrugger, Uta, Falcon-Perez, Juan M., Fu, Qing-Ling, Hill, Andrew F., Lenassi, Metka, Lim, Sai Kiang, Mahoney, My G., Mohanty, Sujata, Moller, Andreas, Nieuwland, Rienk, Ochiya, Takahiro, Sahoo, Susmita, Torrecilhas, Ana C., Zheng, Lei, Zijlstra, Andries, Abuelreich, Sarah, Bagabas, Reem, Bergese, Paolo, Bridges, Esther M., Brucale, Marco ... Guanzon, Dominic (2024). Minimal information for studies of extracellular vesicles (MISEV2023): from basic to advanced approaches: Position paper. Journal of Extracellular Vesicles, 13 (2) e12404, 1-84. doi: 10.1002/jev2.12404 |
|
2024 Journal Article Whole transcriptome profiling of placental pathobiology in SARS‐CoV‐2 pregnancies identifies placental dysfunction signaturesStylianou, Nataly, Sebina, Ismail, Matigian, Nicholas, Monkman, James, Doehler, Hadeel, Röhl, Joan, Allenby, Mark, Nam, Andy, Pan, Liuliu, Rockstroh, Anja, Sadeghirad, Habib, Chung, Kimberly, Sobanski, Thais, O'Byrne, Ken, Almeida, Ana Clara Simoes Florido, Rebutini, Patricia Zadorosnei, Machado‐Souza, Cleber, Stonoga, Emanuele Therezinha Schueda, Warkiani, Majid E., Salomon, Carlos, Short, Kirsty, McClements, Lana, de Noronha, Lucia, Huang, Ruby, Belz, Gabrielle T., Souza‐Fonseca‐Guimaraes, Fernando, Clifton, Vicki and Kulasinghe, Arutha (2024). Whole transcriptome profiling of placental pathobiology in SARS‐CoV‐2 pregnancies identifies placental dysfunction signatures. Clinical and Translational Immunology, 13 (2) e1488, 1-11. doi: 10.1002/cti2.1488 |
|
2024 Journal Article Molecular mechanisms of tumour necrosis factor signalling via TNF receptor 1 and TNF receptor 2 in the tumour microenvironmentAlim, Louisa F., Keane, Colm and Souza-Fonseca-Guimaraes, Fernando (2024). Molecular mechanisms of tumour necrosis factor signalling via TNF receptor 1 and TNF receptor 2 in the tumour microenvironment. Current Opinion in Immunology, 86 102409, 102409. doi: 10.1016/j.coi.2023.102409 |
|
2024 Journal Article IKAROS and AIOLOS directly regulate AP-1 transcriptional complexes and are essential for NK cell developmentGoh, Wilford, Sudholz, Harrison, Foroutan, Momeneh, Scheer, Sebastian, Pfefferle, Aline, Delconte, Rebecca B., Meng, Xiangpeng, Shen, Zihan, Hennessey, Robert, Kong, Isabella Y., Schuster, Iona S., Andoniou, Christopher E., Davis, Melissa J., Hediyeh-Zadeh, Soroor, Souza-Fonseca-Guimaraes, Fernando, Parish, Ian A., Beavis, Paul, Thiele, Daniel, Chopin, Michael, Degli-Esposti, Mariapia A., Cursons, Joe, Kallies, Axel, Rautela, Jai, Nutt, Stephen L. and Huntington, Nicholas D. (2024). IKAROS and AIOLOS directly regulate AP-1 transcriptional complexes and are essential for NK cell development. Nature Immunology, 25 (2), 240-255. doi: 10.1038/s41590-023-01718-4 |
