Overview
Availability
- Dr Natalie Saez is:
- Available for supervision
Qualifications
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Natalie Saez’s works on UQ eSpace
2015
Journal Article
Molecular dynamics and functional studies define a hot spot of crystal contacts essential for PcTx1 inhibition of acid-sensing ion channel 1a
Saez, Natalie J., Deplazes, Evelyne, Cristofori-Armstrong, Ben, Chassagnon, Irene R., Lin, Xiaozhen, Mobli, Mehdi, Mark, Alan E., Rash, Lachlan D. and King, Glenn F. (2015). Molecular dynamics and functional studies define a hot spot of crystal contacts essential for PcTx1 inhibition of acid-sensing ion channel 1a. British Journal of Pharmacology, 172 (20), 4985-4995. doi: 10.1111/bph.13267
2014
Journal Article
High throughput quantitative expression screening and purification applied to recombinant disulfide-rich venom proteins produced in E. coli
Saez, Natalie J., Nozach, Herve, Blemont, Marilyne and Vincentelli, Renaud (2014). High throughput quantitative expression screening and purification applied to recombinant disulfide-rich venom proteins produced in E. coli. Journal of Visualized Experiments, 1091 (89) e51464, 33-53. doi: 10.3791/51464
2014
Book Chapter
High-throughput expression screening and purification of recombinant proteins in E-coli
Saez, Natalie J. and Vincentelli, Renaud (2014). High-throughput expression screening and purification of recombinant proteins in E-coli. Structural genomics: General applications. (pp. 33-53) edited by Yu Wai Chen. New York United States: Humana Press. doi: 10.1007/978-1-62703-691-7_3
2013
Journal Article
Production of recombinant disulfide-rich venom peptides for structural and functional analysis via expression in the periplasm of E. coli
Klint, Julie K., Senff, Sebastian, Saez, Natalie J., Seshadri, Radha, Lau, Ho Yee, Bende, Nira J., Undheim, Eivind A. B., Rash, Lachlan D., Mobli, Mehdi and King, Glenn F. (2013). Production of recombinant disulfide-rich venom peptides for structural and functional analysis via expression in the periplasm of E. coli. PLoS One, 8 (5) e63865, e63865.1-e63865.12. doi: 10.1371/journal.pone.0063865
2013
Journal Article
High throughput screening identifies disulfide isomerase DsbC as a very efficient partner for recombinant expression of small disulfide-rich proteins in E. coli
Nozach, Hervé, Fruchart-Gaillard, Carole, Fenaille, François, Beau, Fabrice, Ramos, Oscar Henrique Pereira, Douzi, Badreddine, Saez, Natalie J., Moutiez, Mireille, Servent, Denis, Gondry, Muriel, Thaï, Robert, Cuniasse, Philippe, Vincentelli, Renaud and Dive, Vincent (2013). High throughput screening identifies disulfide isomerase DsbC as a very efficient partner for recombinant expression of small disulfide-rich proteins in E. coli. Microbial Cell Factories, 12 (37) 37, 1-16. doi: 10.1186/1475-2859-12-37
2013
Other Outputs
Characterising the molecular basis of the interaction between the putative drug target ASIC1a and π-TRTX-Pc1a
Saez, Natalie Jose (2013). Characterising the molecular basis of the interaction between the putative drug target ASIC1a and π-TRTX-Pc1a. PhD Thesis, Institute for Molecular Bioscience, The University of Queensland.
2011
Journal Article
A dynamic pharmacophore drives the interaction between psalmotoxin-1 and the putative drug target acid-sensing ion channel 1a
Saez, Natalie J., Mobli, Mehdi, Bieri, Michael, Chassagnon, Irene R., Malde, Alpeshkumar K., Gamsjaeger, Roland, Mark, Alan E., Gooley, Paul R., Rash. Lachlan D. and King, Glenn F. (2011). A dynamic pharmacophore drives the interaction between psalmotoxin-1 and the putative drug target acid-sensing ion channel 1a. Molecular Pharmacology, 80 (5), 796-808. doi: 10.1124/mol.111.072207
2011
Journal Article
Possible roles for Munc18-1 domain 3a and Syntaxin1 N-peptide and C-terminal anchor in SNARE complex formation
Hu, Shu-Hong, Christie, Michelle P., Saez, Natalie J., Latham, Catherine F., Jarrott, Russell, Lua, Linda H. L., Collins, Brett M. and Martin, Jennifer L. (2011). Possible roles for Munc18-1 domain 3a and Syntaxin1 N-peptide and C-terminal anchor in SNARE complex formation. Proceedings of the National Academy of Sciences of the United States of America, 108 (3), 1040-1045. doi: 10.1073/pnas.0914906108
2010
Journal Article
Spider-venom peptides as therapeutics
Seaz, Natalie J., Senff, Sebastian, Jensen, Jonas E., Er, Sing Yan, Herzig, Volker, Rash, Lachlan D. and King, Glenn F. (2010). Spider-venom peptides as therapeutics. Toxins, 2 (12), 2851-2871. doi: 10.3390/toxins2122851
Funding
Past funding
Supervision
Availability
- Dr Natalie Saez is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Development of a first-in-class biologic drug for stroke
Associate Advisor
Other advisors: Professor Glenn King
Media
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