
Overview
Background
- Deputy Director & Nuclear Medicine Specialist, Department of Nuclear Medicine & Specialised PET Services, Royal Brisbane & Women’s Hospital
- Theranostics Lead, Department of Nuclear Medicine & Specialised PET Services, Royal Brisbane & Women's Hospital
- Co-Director of Training, Department of Nuclear Medicine & Specialised PET Services, Royal Brisbane & Women’s Hospital
- Associate Professor, School of Medicine, University of Queensland
David underwent dual specialty training in both Endocrinology and Nuclear Medicine at Royal Melbourne Hospital, Austin Hospital and Peter MacCallum Cancer Centre in Melbourne. He was appointed a staff specialist at Peter MacCallum Cancer Centre at the completion of his training, where he continued to gain experience in a quaternary referral centre for theranostics treating patients from across south-east Australia and New Zealand. In 2016 he moved to Royal Brisbane & Women’s Hospital where he is currently the Deputy Director of Department of Nuclear Medicine & Specialised PET Services and nuclear medicine lead for the RBWH radionuclide therapy service.
Availability
- Associate Professor David Pattison is:
- Available for supervision
Qualifications
- Bachelor (Honours) of Medicine Surgery, University of Melbourne
- Masters (Coursework) of Public Health, James Cook University
- Royal Australasian College of Physicians, Royal Australasian College of Physicians
Research impacts
David’s major research areas are at the intersection of his two medical specialties – Nuclear Medicine and Endocrinology – with a focus on theranostics for neuroendocrine tumours, thyroid cancer and prostate cancer, in addition to PET imaging of other malignancies. He has been a chief investigator on numerous competitive grants for theranostics, including neuroendocrine tumours (STOPNET $1.25 million MRFF 2024), Australian Research Network for Translation of Targeted Alpha Therapies ($9.76 million MRFF 2022), redifferentiation of radioactive iodine refractory thyroid cancer (I-FIRST $2.7 million MRFF 2021) and prostate cancer (UpFrontPSMA $4 million Movember/Cancer Australia 2019).
David has published 61 peer-reviewed papers, 2 book chapters and over 50 conference abstracts. A/Prof Pattison has delivered 37 invited speaker presentations in the past 5 years. He has been a Principal investigator of numerous prospective theranostics clinical trials, including TheraP, the first randomised controlled trial of [177Lu]Lu-PSMA-617 for metastatic castrate resistant prostate cancer, UpFrontPSMA, ENZA-P and I-FIRST and lead an Australian-first prospective PET imaging trials evaluating [18F]PSMA-1007. He is a member of Australia and New Zealand Urogenital & Prostate (ANZUP) Cancer Trials Group and Australasian Gastro-Intestinal Trials Group (AGITG), and sits on various national trial Management Committees.
David has a prominent national / international profile and professional involvement. Internationally, he sits on the Thyroid and Head and Neck Cancer (THANC) Foundation Medical Advisory Board for Thyroid International Recommendations Online, as the Committee lead for the section on the role of radioactive iodine in diagnostics and therapeutics. Nationally, he is a Board Director for the Australasian Association of Nuclear Medicine Specialists (AANMS) and sits on the AANMS Training Site Advisory Committee and also Theranostics Committee. He was Deputy Chair of the AANMS working group that developed national guidelines for best practice of theranostics in Australia. He is Chair of the Australian Nuclear Science and Technology Organisation (ANSTO) Lutetitium Working Group and is co-author of the Neuroendocrine Tumour Imaging section of the current Clinical Oncology Society of Australia (COSA) Guidelines. He has sat on various national Medical Advisory Boards and the Herston Imaging Research Facility Research Advisory Group, and was the inaugral Chair of the Department of Nuclear Medicine & Specalised PET Services Research Committee. He is a regular reviewer for 10 national and international medical journals in nuclear medicine and endocrinology.
David is enthusiastic about training and mentoring of clinicians, and supervises postgraduate students (University of Queensland) in addition to nuclear medicine advanced trainees (Director of Nuclear Medicine Training at RBWH). As inaugral Chair of the AANMS Theranostics Course & Case Library Committee he convened the successful AANMS Theranostics Course in 2022 and 2024, and contributes to the ANZSNM Scientific & Education Committee since 2022. He is passionate about medical education and was appointed to the Royal Australasian College of Physicians Committee for Joint Clinical Training (JCT) between 2015-2019, including 2 years as National Co-ordinator of Advanced Training in Nuclear Medicine. He regularly provides post-graduate teaching presentations in both Endocrinology and Nuclear Medicine and is a regular examiner for the Nuclear Medicine Oral Assessment Task. He has significant experience with mentoring and innovative introduction of new technology, including leadership of a multidisciplinary team to implement I-124 PET/CT protocol for advanced thyroid cancer, and clinical use of other new PET tracers including [18F]PSMA-1007 & [18F]Fluorocholine.
Works
Search Professor David Pattison’s works on UQ eSpace
2021
Journal Article
The additive diagnostic value of prostate-specific membrane antigen positron emission tomography computed tomography to multiparametric magnetic resonance imaging triage in the diagnosis of prostate cancer (PRIMARY): a prospective multicentre study
Emmett, Louise, Buteau, James, Papa, Nathan, Moon, Daniel, Thompson, James, Roberts, Matthew J., Rasiah, Kris, Pattison, David A., Yaxley, John, Thomas, Paul, Hutton, Anthony C., Agrawal, Shikha, Amin, Amer, Blazevski, Alexandar, Chalasani, Venu, Ho, Bao, Nguyen, Andrew, Liu, Victor, Lee, Jonathan, Sheehan-Dare, Gemma, Kooner, Raji, Coughlin, Geoff, Chan, Lyn, Cusick, Thomas, Namdarian, Benjamin, Kapoor, Jada, Alghazo, Omar, Woo, Henry H., Lawrentschuk, Nathan ... Stricker, Phillip (2021). The additive diagnostic value of prostate-specific membrane antigen positron emission tomography computed tomography to multiparametric magnetic resonance imaging triage in the diagnosis of prostate cancer (PRIMARY): a prospective multicentre study. European Urology, 80 (6), 682-689. doi: 10.1016/j.eururo.2021.08.002
2021
Journal Article
Utility of 68Ga-DOTA-Exendin-4 PET/CT imaging in distinguishing between insulinoma and nesidioblastosis in patients with confirmed endogenous hyperinsulinaemic hypoglycaemia
Kalff, Victor, Iravani, Amir, Ackhurst, Timothy, Pattison, David A., Eu, Peter, Hofman, Michael S. and Hicks, Rodney J. (2021). Utility of 68Ga-DOTA-Exendin-4 PET/CT imaging in distinguishing between insulinoma and nesidioblastosis in patients with confirmed endogenous hyperinsulinaemic hypoglycaemia. Internal Medicine Journal, 51 (10) imj.15141, 1657-1664. doi: 10.1111/imj.15141
2021
Journal Article
Identification of Isolated Hepatic Sarcoidosis With 18F-FDG PET/CT and MRI
Arnfield, Evyn and Pattison, David A (2021). Identification of Isolated Hepatic Sarcoidosis With 18F-FDG PET/CT and MRI. Clinical Nuclear Medicine, 46 (9), e448-e450. doi: 10.1097/rlu.0000000000003613
2021
Journal Article
Dual-tracer positron-emission tomography using prostate-specific membrane antigen and fluorodeoxyglucose for staging of prostate cancer: a systematic review
McGeorge, Stephen, Kwok, Michael, Jiang, Andrew, Emmett, Louise, Pattison, David A., Thomas, Paul A., Yaxley, John W. and Roberts, Matthew J. (2021). Dual-tracer positron-emission tomography using prostate-specific membrane antigen and fluorodeoxyglucose for staging of prostate cancer: a systematic review. Advances in Urology, 2021 1544208, 1544208. doi: 10.1155/2021/1544208
2021
Conference Publication
177Lu-DOTATATE peptide receptor radionuclide therapy (PRRT) in patients with somatostatin-expressing neuroendocrine tumors: a real-world retrospective review of efficacy and safety from an Australian tertiary cancer Center
Nalder, Mark, Ladwa, Rahul, Raina, Anant, Burge, Matthew E., Love, Amanda, Pattison, David A., Ramsay, Stuart and Wyld, David (2021). 177Lu-DOTATATE peptide receptor radionuclide therapy (PRRT) in patients with somatostatin-expressing neuroendocrine tumors: a real-world retrospective review of efficacy and safety from an Australian tertiary cancer Center. 2021 ASCO Annual Meeting I, Virtual, 4-8 June 2021. Alexandria, VA USA: American Society of Clinical Oncology. doi: 10.1200/jco.2021.39.15_suppl.e16198
2021
Journal Article
UpFrontPSMA: a randomized phase 2 study of sequential 177Lu-PSMA-617 and docetaxel vs docetaxel in metastatic hormone-naive prostate cancer (clinical trial protocol)
Dhiantravan, Nattakorn, Emmett, Louise, Joshua, Anthony M., Pattison, David A., Francis, Roslyn J., Williams, Scott, Sandhu, Shahneen, Davis, Ian D., Vela, Ian, Neha, Nitika, Bressel, Mathias, Murphy, Declan G., Hofman, Michael S. and Azad, Arun A. (2021). UpFrontPSMA: a randomized phase 2 study of sequential 177Lu-PSMA-617 and docetaxel vs docetaxel in metastatic hormone-naive prostate cancer (clinical trial protocol). BJU International, 128 (3) bju.15384, 331-342. doi: 10.1111/bju.15384
2021
Journal Article
124I-PET/CT-guided diagnosis and personalized treatment of metastatic papillary thyroid cancer to the pancreas
Wong, Bernadette Z Y, Dickie, Graeme, Garcia, Peter, Scott, Dominique and Pattison, David A. (2021). 124I-PET/CT-guided diagnosis and personalized treatment of metastatic papillary thyroid cancer to the pancreas. Clinical Nuclear Medicine, 46 (4), 337-339. doi: 10.1097/rlu.0000000000003499
2021
Journal Article
Dual Positron Emission Tomography imaging in bronchial neuroendocrine neoplasms (NENs): the NETPET score as a prognostic biomarker
Chan, David L., Ulaner, Gary A., Pattison, David A., Wyld, David, Ladwa, Rahul, Kirchner, Julian, Li, Bob T, Lai, W Victoria, Pavlakis, Nick, Roach, Paul J and Bailey, Dale L (2021). Dual Positron Emission Tomography imaging in bronchial neuroendocrine neoplasms (NENs): the NETPET score as a prognostic biomarker. Journal of Nuclear Medicine, 62 (9), 1278-1284. doi: 10.2967/jnumed.120.257659
2021
Journal Article
Correction to: 68Ga-PSMA PET/CT tumour intensity pre-operatively predicts adverse pathological outcomes and progression-free survival in localised prostate cancer (European Journal of Nuclear Medicine and Molecular Imaging, (2021), 48, 2, (477-482), 10.1007/s00259-020-04944-2)
Roberts, Matthew J., Morton, Andrew, Donato, Peter, Kyle, Samuel, Pattison, David A., Thomas, Paul, Coughlin, Geoff, Esler, Rachel, Dunglison, Nigel, Gardiner, Robert A., Doi, Suhail A., Emmett, Louise and Yaxley, John (2021). Correction to: 68Ga-PSMA PET/CT tumour intensity pre-operatively predicts adverse pathological outcomes and progression-free survival in localised prostate cancer (European Journal of Nuclear Medicine and Molecular Imaging, (2021), 48, 2, (477-482), 10.1007/s00259-020-04944-2). European Journal of Nuclear Medicine and Molecular Imaging, 48 (2), 655-656. doi: 10.1007/s00259-020-04983-9
2021
Journal Article
Prospective intra-individual blinded comparison of [18F]PSMA-1007 and [68 Ga]Ga-PSMA-11 PET/CT imaging in patients with confirmed prostate cancer
Pattison, David A., Debowski, Maciej, Gulhane, Brook, Arnfield, Evyn G., Pelecanos, Anita M., Garcia, Peter L., Latter, Melissa J., Lin, Charles Y., Roberts, Matthew J., Ramsay, Stuart C. and Thomas, Paul A. (2021). Prospective intra-individual blinded comparison of [18F]PSMA-1007 and [68 Ga]Ga-PSMA-11 PET/CT imaging in patients with confirmed prostate cancer. European Journal of Nuclear Medicine and Molecular Imaging, 49 (2), 763-776. doi: 10.1007/s00259-021-05520-y
2021
Journal Article
Correction to: Prospective intra‑individual blinded comparison of [18F]PSMA‑1007 and [68 Ga]Ga‑PSMA‑11 PET/CT imaging in patients with confirmed prostate cancer (European Journal of Nuclear Medicine and Molecular Imaging, (2021), 10.1007/s00259-021-05520-y)
Pattison, David A., Debowski, Maciej, Gulhane, Brook, Arnfield, Evyn G., Pelecanos, Anita M., Garcia, Peter L., Latter, Melissa J., Lin, Charles Y., Roberts, Matthew J., Ramsay, Stuart C. and Thomas, Paul A. (2021). Correction to: Prospective intra‑individual blinded comparison of [18F]PSMA‑1007 and [68 Ga]Ga‑PSMA‑11 PET/CT imaging in patients with confirmed prostate cancer (European Journal of Nuclear Medicine and Molecular Imaging, (2021), 10.1007/s00259-021-05520-y). European Journal of Nuclear Medicine and Molecular Imaging, 49 (2), 789-789. doi: 10.1007/s00259-021-05548-0
2020
Journal Article
Octreotide for resuscitation of cardiac arrest due to carcinoid crisis precipitated by novel peptide receptor radionuclide therapy (PRRT): A case report
Dhanani, Jayesh, Pattison, David A., Burge, Matthew, Williams, Julian, Riedel, Bernhard, Hicks, Rodney J. and Reade, Michael C. (2020). Octreotide for resuscitation of cardiac arrest due to carcinoid crisis precipitated by novel peptide receptor radionuclide therapy (PRRT): A case report. Journal of Critical Care, 60, 319-322. doi: 10.1016/j.jcrc.2020.08.011
2020
Journal Article
The utility of pharmacological and radiological interventions to optimize diagnostic information from PET/CT
Dudoignon, David, Pattison, David A., Legallois, Damien, Hicks, Rodney J. and Aide, Nicolas (2020). The utility of pharmacological and radiological interventions to optimize diagnostic information from PET/CT. Cancer Imaging, 20 (1) 68, 1-12. doi: 10.1186/s40644-020-00344-9
2020
Journal Article
68Ga-PSMA PET/CT tumour intensity pre-operatively predicts adverse pathological outcomes and progression-free survival in localised prostate cancer
Roberts, Matthew J., Morton, Andrew, Donato, Peter, Kyle, Samuel, Pattison, David A., Thomas, Paul, Coughlin, Geoff, Esler, Rachel, Dunglison, Nigel, Gardiner, Robert A., Doi, Suhail A., Emmett, Louise and Yaxley, John (2020). 68Ga-PSMA PET/CT tumour intensity pre-operatively predicts adverse pathological outcomes and progression-free survival in localised prostate cancer. European Journal of Nuclear Medicine and Molecular Imaging, 48 (2), 655-656. doi: 10.1007/s00259-020-04944-2
2020
Journal Article
Long-term follow-up and outcomes of retreatment in an expanded 50-patient single-center phase II prospective trial of 177Lu-PSMA-617 theranostics in metastatic castration-resistant prostate cancer
Violet, John, Sandhu, Shahneen, Iravani, Amir, Ferdinandus, Justin, Sue-Ping Thang, , Kong, Grace, Kumar, Aravind Ravi, Akhurst, Tim, Pattison, David, Beaulieu, Alexis, Mooi, Jennifer, Tran, Ben, Guo, Christina, Kalff, Victor, Murphy, Declan G., Jackson, Price, Eu, Peter, Scalzo, Mark, Williams, Scott G., Hicks, Rod J., Hofman, Michael S. and Tran, Ben (2020). Long-term follow-up and outcomes of retreatment in an expanded 50-patient single-center phase II prospective trial of 177Lu-PSMA-617 theranostics in metastatic castration-resistant prostate cancer. Journal of Nuclear Medicine, 61 (6), 857-865. doi: 10.2967/jnumed.119.236414
2020
Journal Article
Re: Long Term Follow-Up and Outcomes of Re-Treatment in an Expanded 50 Patient Single-Center Phase II Prospective Trial of Lutetium-177 (177Lu) PSMA-617 Theranostics in Metastatic Castrate-Resistant Prostate Cancer
Violet, J., Sandhu, S., Iravani, A., Ferdinandus, J., Thang, S. P., Kong, G., Kumar, A. Ravi, Akhurst, T., Pattison, D. A., Beaulieu, A., Mooi, J., Guo, C., Kalff, V., Murphy, D. G., Jackson, P., Eu, P., Scalzo, M., Williams, S., Hicks, R. J. and Hofman, M. S. (2020). Re: Long Term Follow-Up and Outcomes of Re-Treatment in an Expanded 50 Patient Single-Center Phase II Prospective Trial of Lutetium-177 (177Lu) PSMA-617 Theranostics in Metastatic Castrate-Resistant Prostate Cancer. Journal of Urology, 203 (5). doi: 10.1097/JU.0000000000000779.01
2019
Conference Publication
Combination of avelumabwith peptide receptor radionuclide therapy (PRRT) or conventional fractionated radiotherapy (RT) in metastatic merkel cell carcinoma (mMCC) [GoTHAM study]
Sandhu, Shahneen, Tothill, Richard, Scolyer, Richard, Guminski, Alexander, Becker, Juergen, Poulsen, Michael, Atkinson, Victoria, Neeson, Paul, Shackleton, Mark, Pattison, David, Williams, Narelle and Paton, Elizabeth (2019). Combination of avelumabwith peptide receptor radionuclide therapy (PRRT) or conventional fractionated radiotherapy (RT) in metastatic merkel cell carcinoma (mMCC) [GoTHAM study]. COSA's 46th Annual Scientific Meeting, Urological cancer; Age and gender in cancer practice; Digital health in cancer, Adelaide, SA, Australia, 12–14 November 2019. Hoboken, NJ, United States: Wiley.
2019
Conference Publication
A prospective intra-individual blinded comparison of 18F-PSMA-1007 and 68GA-PSMA-11 PET/CT imaging in patients with confirmed prostate cancer
Debowski, M., Gulhane, B., Ramsay, S. C., Thomas, P. A., Garcia, P., Latter, M., Tapper, S. and Pattison, D. A. (2019). A prospective intra-individual blinded comparison of 18F-PSMA-1007 and 68GA-PSMA-11 PET/CT imaging in patients with confirmed prostate cancer. Australian and New Zealand Society of Nuclear Medicine (ANZSNM) 49th ASM, Adelaide, SA, Australia, 26–28 April 2019. Hoboken, NJ, United States: Wiley.
2018
Conference Publication
Targeted Molecular Imaging of Translocator Protein (TSPO) Using (18F)GE180-PET for the Diagnosis of Gastrointestinal Graft Versus host Disease (GI-GVHD)
Scott, Ashleigh P., Tey, Siok-Keen, Thomas, Paul, Pattison, David and Kennedy, Glen A. (2018). Targeted Molecular Imaging of Translocator Protein (TSPO) Using (18F)GE180-PET for the Diagnosis of Gastrointestinal Graft Versus host Disease (GI-GVHD). 60th Annual Meeting of the American Society of Hematology (ASH), San Diego, CA United States, 1-4 December 2018. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2018-99-114114
2018
Journal Article
64Cu-SARTATE PET imaging of patients with neuroendocrine tumors demonstrates high tumor uptake and retention, potentially allowing prospective dosimetry for peptide receptor radionuclide therapy
Hicks, Rodney J., Jackson, Price, Kong, Grace, Ware, Robert E., Hofman, Michael S., Pattison, David A., Akhurst, Timothy A., Drummond, Elizabeth, Roselt, Peter, Callahan, Jason, Price, Roger, Jeffery, Charmaine M., Hong, Emily, Noonan, Wayne, Herschtal, Alan, Hicks, Lauren J., Hedt, Amos, Harris, Matthew, Paterson, Brett M. and Donnelly, Paul S. (2018). 64Cu-SARTATE PET imaging of patients with neuroendocrine tumors demonstrates high tumor uptake and retention, potentially allowing prospective dosimetry for peptide receptor radionuclide therapy. Journal of Nuclear Medicine, 60 (6), 777-785. doi: 10.2967/jnumed.118.217745
Funding
Past funding
Supervision
Availability
- Associate Professor David Pattison is:
- Available for supervision
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Supervision history
Current supervision
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Master Philosophy
State-of-the-art imaging and genetic testing for phaeochromocytomas and paragangliomas: the Royal Brisbane & Women's Hospital experience
Principal Advisor
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Doctor Philosophy
PARA-PET: a randomised trial of [18F]FCH vs conventional imaging for primary hyperparathyroidism
Principal Advisor
Completed supervision
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2024
Master Philosophy
21st Century Approaches for Imaging and Genetic Testing for Phaeochromocytomas and Paragangliomas
Principal Advisor
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2020
Master Philosophy
Predictors of dosimetry and outcome to peptide receptor radionuclide therapy in metastatic neuroendocrine tumour.
Associate Advisor
Other advisors: Associate Professor David Wyld
Media
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