
Overview
Background
- Deputy Director & Nuclear Medicine Specialist, Department of Nuclear Medicine & Specialised PET Services, Royal Brisbane & Women’s Hospital
- Theranostics Lead, Department of Nuclear Medicine & Specialised PET Services, Royal Brisbane & Women's Hospital
- Co-Director of Training, Department of Nuclear Medicine & Specialised PET Services, Royal Brisbane & Women’s Hospital
- Associate Professor, School of Medicine, University of Queensland
David underwent dual specialty training in both Endocrinology and Nuclear Medicine at Royal Melbourne Hospital, Austin Hospital and Peter MacCallum Cancer Centre in Melbourne. He was appointed a staff specialist at Peter MacCallum Cancer Centre at the completion of his training, where he continued to gain experience in a quaternary referral centre for theranostics treating patients from across south-east Australia and New Zealand. In 2016 he moved to Royal Brisbane & Women’s Hospital where he is currently the Deputy Director of Department of Nuclear Medicine & Specialised PET Services and nuclear medicine lead for the RBWH radionuclide therapy service.
Availability
- Associate Professor David Pattison is:
- Available for supervision
Qualifications
- Bachelor (Honours) of Medicine Surgery, University of Melbourne
- Masters (Coursework) of Public Health, James Cook University
- Royal Australasian College of Physicians, Royal Australasian College of Physicians
Research impacts
David’s major research areas are at the intersection of his two medical specialties – Nuclear Medicine and Endocrinology – with a focus on theranostics for neuroendocrine tumours, thyroid cancer and prostate cancer, in addition to PET imaging of other malignancies. He has been a chief investigator on numerous competitive grants for theranostics, including neuroendocrine tumours (STOPNET $1.25 million MRFF 2024), Australian Research Network for Translation of Targeted Alpha Therapies ($9.76 million MRFF 2022), redifferentiation of radioactive iodine refractory thyroid cancer (I-FIRST $2.7 million MRFF 2021) and prostate cancer (UpFrontPSMA $4 million Movember/Cancer Australia 2019).
David has published 61 peer-reviewed papers, 2 book chapters and over 50 conference abstracts. A/Prof Pattison has delivered 37 invited speaker presentations in the past 5 years. He has been a Principal investigator of numerous prospective theranostics clinical trials, including TheraP, the first randomised controlled trial of [177Lu]Lu-PSMA-617 for metastatic castrate resistant prostate cancer, UpFrontPSMA, ENZA-P and I-FIRST and lead an Australian-first prospective PET imaging trials evaluating [18F]PSMA-1007. He is a member of Australia and New Zealand Urogenital & Prostate (ANZUP) Cancer Trials Group and Australasian Gastro-Intestinal Trials Group (AGITG), and sits on various national trial Management Committees.
David has a prominent national / international profile and professional involvement. Internationally, he sits on the Thyroid and Head and Neck Cancer (THANC) Foundation Medical Advisory Board for Thyroid International Recommendations Online, as the Committee lead for the section on the role of radioactive iodine in diagnostics and therapeutics. Nationally, he is a Board Director for the Australasian Association of Nuclear Medicine Specialists (AANMS) and sits on the AANMS Training Site Advisory Committee and also Theranostics Committee. He was Deputy Chair of the AANMS working group that developed national guidelines for best practice of theranostics in Australia. He is Chair of the Australian Nuclear Science and Technology Organisation (ANSTO) Lutetitium Working Group and is co-author of the Neuroendocrine Tumour Imaging section of the current Clinical Oncology Society of Australia (COSA) Guidelines. He has sat on various national Medical Advisory Boards and the Herston Imaging Research Facility Research Advisory Group, and was the inaugral Chair of the Department of Nuclear Medicine & Specalised PET Services Research Committee. He is a regular reviewer for 10 national and international medical journals in nuclear medicine and endocrinology.
David is enthusiastic about training and mentoring of clinicians, and supervises postgraduate students (University of Queensland) in addition to nuclear medicine advanced trainees (Director of Nuclear Medicine Training at RBWH). As inaugral Chair of the AANMS Theranostics Course & Case Library Committee he convened the successful AANMS Theranostics Course in 2022 and 2024, and contributes to the ANZSNM Scientific & Education Committee since 2022. He is passionate about medical education and was appointed to the Royal Australasian College of Physicians Committee for Joint Clinical Training (JCT) between 2015-2019, including 2 years as National Co-ordinator of Advanced Training in Nuclear Medicine. He regularly provides post-graduate teaching presentations in both Endocrinology and Nuclear Medicine and is a regular examiner for the Nuclear Medicine Oral Assessment Task. He has significant experience with mentoring and innovative introduction of new technology, including leadership of a multidisciplinary team to implement I-124 PET/CT protocol for advanced thyroid cancer, and clinical use of other new PET tracers including [18F]PSMA-1007 & [18F]Fluorocholine.
Works
Search Professor David Pattison’s works on UQ eSpace
2024
Book Chapter
Role of Functional Imaging in NENs
Chan, David L., Pattison, David A. and Kong, Grace (2024). Role of Functional Imaging in NENs. Endocrinology. (pp. 1-24) Cham, Switzerland: Springer. doi: 10.1007/978-3-030-67823-4_8-1
2023
Journal Article
Cardiac metastases from neuroendocrine neoplasms: complementary role of SSTR PET/CT and cardiac MRI
Arnfield, Evyn G., Tam, Laura, Pattison, David A., Younger, John, Chikatamarla, Venkata Avinash, Wyld, David, Burge, Matthew, McCormack, Louise, Ladwa, Rahul and Ramsay, Stuart (2023). Cardiac metastases from neuroendocrine neoplasms: complementary role of SSTR PET/CT and cardiac MRI. Journal of Nuclear Cardiology, 30 (6), 2676-2691. doi: 10.1007/s12350-023-03345-w
2023
Journal Article
Clinical impact of Prostate-Specific Membrane Antigen Positron Emission Tomography (PET) on intensification or deintensification of advanced renal cell carcinoma management
Pathmanathan, Shivanshan, Tariq, Arsalan, Pearce, Adam, Rhee, Handoo, Kyle, Samuel, Raveenthiran, Sheliyan, Wong, David, McBean, Rhiannon, Marsh, Phillip, Goodman, Steven, Dhiantravan, Nattakorn, Esler, Rachel, Dunglison, Nigel, Navaratnam, Anojan, Yaxley, John, Thomas, Paul, Pattison, David A., Goh, Jeffrey C., Gan, Chun Loo and Roberts, Matthew J. (2023). Clinical impact of Prostate-Specific Membrane Antigen Positron Emission Tomography (PET) on intensification or deintensification of advanced renal cell carcinoma management. European Journal of Nuclear Medicine and Molecular Imaging, 51 (1), 295-303. doi: 10.1007/s00259-023-06380-4
2023
Journal Article
Delineation and agreement of FET PET biological volumes in glioblastoma: results of the nuclear medicine credentialing program from the prospective, multi-centre trial evaluating FET PET In Glioblastoma (FIG) study—TROG 18.06
Barry, Nathaniel, Francis, Roslyn J., Ebert, Martin A., Koh, Eng-Siew, Rowshanfarzad, Pejman, Hassan, Ghulam Mubashar, Kendrick, Jake, Gan, Hui K., Lee, Sze T., Lau, Eddie, Moffat, Bradford A., Fitt, Greg, Moore, Alisha, Thomas, Paul, Pattison, David A., Akhurst, Tim, Alipour, Ramin, Thomas, Elizabeth L., Hsiao, Edward, Schembri, Geoffrey P., Lin, Peter, Ly, Tam, Yap, June, Kirkwood, Ian, Vallat, Wilson, Khan, Shahroz, Krishna, Dayanethee, Ngai, Stanley, Yu, Chris ... Scott, Andrew M. (2023). Delineation and agreement of FET PET biological volumes in glioblastoma: results of the nuclear medicine credentialing program from the prospective, multi-centre trial evaluating FET PET In Glioblastoma (FIG) study—TROG 18.06. European Journal of Nuclear Medicine and Molecular Imaging, 50 (13), 3970-3981. doi: 10.1007/s00259-023-06371-5
2023
Conference Publication
Initial diagnostic accuracy of FDG-PET compared to PSMA-PET for newly diagnosed high risk prostate cancer prior to treatment: FIND Trial
Roberts, Matthew, Roberts, Natasha, Harley, Simon, Cullen, Karla, Pelecanos, Anita, Vela, Ian, Yaxley, John, Kuchel, Anna, Dhiantravan, Nattakorn, Thomas, Paul and Pattison, David (2023). Initial diagnostic accuracy of FDG-PET compared to PSMA-PET for newly diagnosed high risk prostate cancer prior to treatment: FIND Trial. 2023 ANZUP Annual Scientific Meeting, Bouncing Back, Melbourne, VIC, Australia, 9-11 July 2023. Hoboken, NJ, United States: Wiley.
2023
Journal Article
Australasian consensus statement on the identification, prevention and management of hormonal crises in patients with neuroendocrine neoplasms (NENs) undergoing peptide receptor radionuclide therapy (PRRT)
Li, Minmin, Chan, David L., Tapia Rico, Gonzalo, Cehic, Gabrielle, Lawrence, Ben, Wyld, David, Pattison, David A., Kong, Grace, Hicks, Rodney, Michael, Michael, Kiberu, Andrew Ddembe, Lim, Jennifer, Clifton-Bligh, Roderick, Tsang, Venessa, Roach, Paul J., Leyden, John, Diakos, Connie I., Price, Timothy J. and Pavlakis, Nick (2023). Australasian consensus statement on the identification, prevention and management of hormonal crises in patients with neuroendocrine neoplasms (NENs) undergoing peptide receptor radionuclide therapy (PRRT). Neuroendocrinology, 113 (3), 281-288. doi: 10.1159/000526848
2023
Conference Publication
Evolution: Phase II study of radionuclide <sup>177</sup>Lu-PSMA-617 therapy versus <sup>177</sup>Lu-PSMA-617 in combination with ipilimumab and nivolumab for men with metastatic castration-resistant prostate cancer (mCRPC; ANZUP 2001)
Sandhu, Shahneen, Subramaniam, Shalini, Hofman, Michael S., Stockler, Martin R., Martin, Andrew James, Pokorski, Izabella, Goh, Jeffrey C., Pattison, David A., Dhiantravan, Nattakorn, Gedye, Craig, Rutherford, Natalie K., Joshua, Anthony M., Tan, Thean Hsiang, Kirkwood, Ian D., Lee, Sze Ting, Weickhardt, Andrew James, Alipour, Ramin, Nguyen, Andrew, Davis, Ian D., Emmett, Louise and The Australian and New Zealand Urogenital and Prostate Cancer Trials Group (ANZUP) (2023). Evolution: Phase II study of radionuclide 177Lu-PSMA-617 therapy versus 177Lu-PSMA-617 in combination with ipilimumab and nivolumab for men with metastatic castration-resistant prostate cancer (mCRPC; ANZUP 2001). 2023 ASCO Genitourinary Cancers Symposium, San Francisco, CA United States, 16-18 February 2023. Alexandria, VA United States: American Society of Clinical Oncology. doi: 10.1200/jco.2023.41.6_suppl.tps271
2022
Journal Article
Regional differences in the reduction in cerebral FDG uptake induced by the ketogenic diet
Bennett, O. A., Ramsay, S. C., Malacova, E., Bourgeat, P., Goodman, S. J., Dunn, C. J., Robinson, B. M., Lee, K. and Pattison, D. A. (2022). Regional differences in the reduction in cerebral FDG uptake induced by the ketogenic diet. European Journal of Hybrid Imaging, 6 (1) 29, 1-16. doi: 10.1186/s41824-022-00150-5
2022
Journal Article
PSMA and FDG-PET as predictive and prognostic biomarkers in patients given [177Lu]Lu-PSMA-617 versus cabazitaxel for metastatic castration-resistant prostate cancer (TheraP): a biomarker analysis from a randomised, open-label, phase 2 trial
Buteau, James P, Martin, Andrew J, Emmett, Louise, Iravani, Amir, Sandhu, Shahneen, Joshua, Anthony M, Francis, Roslyn J, Zhang, Alison Y, Scott, Andrew M, Lee, Sze-Ting, Azad, Arun A, McJannett, Margaret M, Stockler, Martin R, Williams, Scott G, Davis, Ian D, Hofman, Michael S, Akhurst, Tim, Alipour, Ramin, Banks, Patricia, Beaulieu, Alexis, Chua, Wei, Dhiantravan, Nattakorn, Ford, Kate, Gedye, Craig, Goh, Jeffrey C, Guminski, Alex, Hamid, Anis, Haskali, Mohammad B, Hicks, Rodney J ... for the TheraP Trial Investigators and the Australian and New Zealand Urogenital and Prostate Cancer Trials Group (2022). PSMA and FDG-PET as predictive and prognostic biomarkers in patients given [177Lu]Lu-PSMA-617 versus cabazitaxel for metastatic castration-resistant prostate cancer (TheraP): a biomarker analysis from a randomised, open-label, phase 2 trial. The Lancet Oncology, 23 (11), 1389-1397. doi: 10.1016/S1470-2045(22)00605-2
2022
Journal Article
99mTc-Sestamibi Thyroid Scintigraphy in Amiodarone-Induced Thyrotoxicosis: Functional Imaging-Histopathologic Correlation
Wang, Ray, Better, Nathan, Sivaratnam, Dinesh, Westcott, James, Forehan, Simon, Christie, Michael, Pattison, David A. and Fourlanos, Spiros (2022). 99mTc-Sestamibi Thyroid Scintigraphy in Amiodarone-Induced Thyrotoxicosis: Functional Imaging-Histopathologic Correlation. Clinical Nuclear Medicine, 47 (9), E582-E584. doi: 10.1097/RLU.0000000000004332
2022
Journal Article
Characterization of tumor thrombus in renal cell carcinoma with prostate specific membrane antigen (PSMA) positron emission tomography (PET)/computed tomography (CT)
Tariq, Arsalan, McGeorge, Stephen, Pearce, Adam, Rhee, Handoo, Wood, Simon, Kyle, Samuel, Marsh, Philip, Raveenthiran, Sheliyan, Wong, David, McBean, Rhiannon, Westera, Jurjen, Dunglison, Nigel, Esler, Rachel, Navaratnam, Anojan, Yaxley, John, Thomas, Paul, Pattison, David A. and Roberts, Matthew J. (2022). Characterization of tumor thrombus in renal cell carcinoma with prostate specific membrane antigen (PSMA) positron emission tomography (PET)/computed tomography (CT). Urologic Oncology: Seminars and Original Investigations, 40 (6), 276.e1-276.e9. doi: 10.1016/j.urolonc.2022.03.007
2022
Conference Publication
TheraP: <sup>177</sup>Lu-PSMA-617 (LuPSMA) versus cabazitaxel in metastatic castration-resistant prostate cancer (mCRPC) progressing after docetaxel-Overall survival after median follow-up of 3 years (ANZUP 1603)
Hofman, Michael S., Emmett, Louise, Sandhu, Shahneen, Iravani, Amir, Joshua, Anthony M., Goh, Jeffrey C., Pattison, David A., Tan, Thean Hsiang, Kirkwood, Ian D., Francis, Roslyn J., Gedye, Craig, Rutherford, Natalie K., Zhang, Alison Yan, McJannett, Margaret Mary, Stockler, Martin R., Williams, Scott, Martin, Andrew James and Davis, Ian D. (2022). TheraP: 177Lu-PSMA-617 (LuPSMA) versus cabazitaxel in metastatic castration-resistant prostate cancer (mCRPC) progressing after docetaxel-Overall survival after median follow-up of 3 years (ANZUP 1603). Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Virtual, 3-7 June 2022. Philadelphia, PA USA: Lippincott Williams & Wilkins.
2022
Conference Publication
Prostate-specific membrane antigen (PSMA) positron emission tomography (PET) compared to computed tomography (CT) for advanced renal cell carcinoma (RCC)
Pathmanathan, Shivanshan, Tariq, Arsalan, Gan, Chun Loo, Pearce, Adam, Rhee, Handoo, Kyle, Samuel, Raveenthiran, Sheliyan, Wong, David, McBean, Rhiannon, Marsh, Philip, Goodman, Steven, Dhiantravan, Nattakorn, Esler, Rachel, Dunglison, Nigel, Navaratnam, Anojan, Yaxley, John, Thomas, Paul, Pattison, David A., Goh, Jeffrey C. and Roberts, Matthew (2022). Prostate-specific membrane antigen (PSMA) positron emission tomography (PET) compared to computed tomography (CT) for advanced renal cell carcinoma (RCC). Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Electr Network, 3-7 June 2022. Alexandria, VA, United States: American Society of Clinical Oncology. doi: 10.1200/JCO.2022.40.16_suppl.4540
2022
Journal Article
All Prostate-specific Membrane Antigen Peptides Are Equal, but Some Are More Equal than Others
Emmett, Louise, Pattison, David A. and Roberts, Matthew J. (2022). All Prostate-specific Membrane Antigen Peptides Are Equal, but Some Are More Equal than Others. European urology oncology, 5 (3), 283-284. doi: 10.1016/j.euo.2022.04.002
2022
Journal Article
The importance of training, accreditation, and guidelines for the practice of theranostics: the Australian perspective
Lee, Sze Ting, Emmett, Louise M., Pattison, David A., Hofman, Michael S., Bailey, Dale L., Latter, Melissa J., Francis, Roslyn J. and Scott, Andrew M. (2022). The importance of training, accreditation, and guidelines for the practice of theranostics: the Australian perspective. Journal of Nuclear Medicine, 63 (6), 819-822. doi: 10.2967/jnumed.122.263996
2022
Conference Publication
Australasian Gastrointestinal Trials Group (AGITG) CONTROL NET Study: <SUP>177</SUP>Lu-DOTATATE peptide receptor radionuclide therapy (PRRT) and capecitabine plus temozolomide (CAPTEM) for pancreas and midgut neuroendocrine tumours (pNETS, mNETS)-Final results
Pavlakis, Nick, Ransom, David Turner, Wyld, David, Sjoquist, Katrin Marie, Wilson, Kate, Gebski, Val, Murray, James, Kiberu, Andrew Ddembe, Burge, Matthew E., Macdonald, William, Roach, Paul, Pattison, David A., Butler, Patrick, Price, Timothy Jay, Michael, Michael, Lawrence, Benjamin James, Bailey, Dale L., Leyden, Simone, Zalcberg, John Raymond and Turner, Harvey (2022). Australasian Gastrointestinal Trials Group (AGITG) CONTROL NET Study: 177Lu-DOTATATE peptide receptor radionuclide therapy (PRRT) and capecitabine plus temozolomide (CAPTEM) for pancreas and midgut neuroendocrine tumours (pNETS, mNETS)-Final results. Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Electr Network, Jun 03-07, 2022. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.
2022
Journal Article
The role of dual tracer PSMA and FDG PET/CT in renal cell carcinoma (RCC) compared to conventional imaging: A multi-institutional case series with intra-individual comparison
Tariq, Arsalan, Kwok, Michael, Pearce, Adam, Rhee, Handoo, Kyle, Samuel, Marsh, Phillip, Raveenthiran, Sheliyan, Wong, David, McBean, Rhiannon, Westera, Jurjen, Dunglison, Nigel, Esler, Rachel, Navaratnam, Anojan, Yaxley, John W., Thomas, Paul, Pattison, David A. and Roberts, Matthew J. (2022). The role of dual tracer PSMA and FDG PET/CT in renal cell carcinoma (RCC) compared to conventional imaging: A multi-institutional case series with intra-individual comparison. Urologic Oncology: Seminars and Original Investigations, 40 (2) 66.e1, 66.e1-66.e9. doi: 10.1016/j.urolonc.2021.11.006
2022
Journal Article
[18F]GE-180 PET/CT assessment of enterocytic translocator protein (TSPO) over-expression: a pilot study in gastrointestinal GVHD
Scott, Ashleigh P., Thomas, Paul, Pattison, David A., Francis, Leo, Ridge, Paula, Tey, Siok-Keen and Kennedy, Glen A. (2022). [18F]GE-180 PET/CT assessment of enterocytic translocator protein (TSPO) over-expression: a pilot study in gastrointestinal GVHD. Bone Marrow Transplantation, 57 (3), 517-519. doi: 10.1038/s41409-022-01571-3
2022
Journal Article
Lymph node classification in E-PSMA reporting guidelines for PSMA-PET
Arnfield, Evyn G., Roberts, Matthew J. and Pattison, David A. (2022). Lymph node classification in E-PSMA reporting guidelines for PSMA-PET. European Journal of Nuclear Medicine and Molecular Imaging, 50 (1), 1-2. doi: 10.1007/s00259-022-05943-1
2021
Journal Article
Risk of metastatic disease using [18F]PSMA-1007 PET/CT for primary prostate cancer staging
Chikatamarla, Venkata Avinash, Okano, Satomi, Jenvey, Peter, Ansaldo, Alexander, Roberts, Matthew J., Ramsay, Stuart C., Thomas, Paul A. and Pattison, David A. (2021). Risk of metastatic disease using [18F]PSMA-1007 PET/CT for primary prostate cancer staging. EJNMMI Research, 11 (1) 128, 128. doi: 10.1186/s13550-021-00869-5
Funding
Past funding
Supervision
Availability
- Associate Professor David Pattison is:
- Available for supervision
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Supervision history
Current supervision
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Master Philosophy
State-of-the-art imaging and genetic testing for phaeochromocytomas and paragangliomas: the Royal Brisbane & Women's Hospital experience
Principal Advisor
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Doctor Philosophy
PARA-PET: a randomised trial of [18F]FCH vs conventional imaging for primary hyperparathyroidism
Principal Advisor
Completed supervision
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2024
Master Philosophy
21st Century Approaches for Imaging and Genetic Testing for Phaeochromocytomas and Paragangliomas
Principal Advisor
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2020
Master Philosophy
Predictors of dosimetry and outcome to peptide receptor radionuclide therapy in metastatic neuroendocrine tumour.
Associate Advisor
Other advisors: Associate Professor David Wyld
Media
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