Overview
Background
- Director, Department of Nuclear Medicine & PET Services, Royal Brisbane & Women’s Hospital
- Theranostics Lead, Department of Nuclear Medicine & Specialised PET Services, Royal Brisbane & Women's Hospital
- Co-Director of Training, Department of Nuclear Medicine & Specialised PET Services, Royal Brisbane & Women’s Hospital
- Professor, School of Medicine, University of Queensland
David underwent dual specialty training in both Endocrinology and Nuclear Medicine at Royal Melbourne Hospital, Austin Hospital and Peter MacCallum Cancer Centre in Melbourne. He was appointed a staff specialist at Peter MacCallum Cancer Centre at the completion of his training, where he continued to gain experience in a quaternary referral centre for theranostics treating patients from across south-east Australia and New Zealand. In 2016 he moved to Royal Brisbane & Women’s Hospital where he is currently the Director of Department of Nuclear Medicine & PET Services and nuclear medicine lead for the RBWH radionuclide therapy service.
Availability
- Professor David Pattison is:
- Not available for supervision
Qualifications
- Bachelor (Honours) of Medicine Surgery, University of Melbourne
- Masters (Coursework) of Public Health, James Cook University
- Royal Australasian College of Physicians, Royal Australasian College of Physicians
Research impacts
David’s major research areas are at the intersection of his two medical specialties – Nuclear Medicine and Endocrinology – with a focus on theranostics for neuroendocrine tumours, thyroid cancer and prostate cancer, in addition to PET imaging of other malignancies. He has been a chief investigator on numerous competitive grants for theranostics, including neuroendocrine tumours (STOPNET $1.25 million MRFF 2024), Australian Research Network for Translation of Targeted Alpha Therapies ($9.76 million MRFF 2022), redifferentiation of radioactive iodine refractory thyroid cancer (I-FIRST $2.7 million MRFF 2021) and prostate cancer (UpFrontPSMA $4 million Movember/Cancer Australia 2019).
David has published 63 peer-reviewed papers, 3 book chapters and over 50 conference abstracts. Prof Pattison has delivered 37 invited speaker presentations in the past 5 years. He has been a Principal investigator of numerous prospective theranostics clinical trials, including TheraP, the first randomised controlled trial of [177Lu]Lu-PSMA-617 for metastatic castrate resistant prostate cancer, UpFrontPSMA, ENZA-P and I-FIRST and lead an Australian-first prospective PET imaging trials evaluating [18F]PSMA-1007. He is a member of Australia and New Zealand Urogenital & Prostate (ANZUP) Cancer Trials Group and Australasian Gastro-Intestinal Trials Group (AGITG), and sits on various national trial Management Committees.
David has a prominent national / international profile and professional involvement. Internationally, he sits on the Thyroid and Head and Neck Cancer (THANC) Foundation Medical Advisory Board for Thyroid International Recommendations Online, as the Committee lead for the section on the role of radioactive iodine in diagnostics and therapeutics. Nationally, he is a Board Director for the Australasian Association of Nuclear Medicine Specialists (AANMS) and sits on the AANMS Training Site Advisory Committee and also Theranostics Committee. He was Deputy Chair of the AANMS working group that developed national guidelines for best practice of theranostics in Australia. He is Chair of the Australian Nuclear Science and Technology Organisation (ANSTO) Lutetitium Working Group and is co-author of the Neuroendocrine Tumour Imaging section of the current Clinical Oncology Society of Australia (COSA) Guidelines. He has sat on various national Medical Advisory Boards and the Herston Imaging Research Facility Research Advisory Group, and was the inaugral Chair of the Department of Nuclear Medicine & Specalised PET Services Research Committee. He is a regular reviewer for 10 national and international medical journals in nuclear medicine and endocrinology.
David is enthusiastic about training and mentoring of clinicians, and supervises postgraduate students (University of Queensland) in addition to nuclear medicine advanced trainees (Director of Nuclear Medicine Training at RBWH). As inaugral Chair of the AANMS Theranostics Course & Case Library Committee he convened the successful AANMS Theranostics Course in 2022 and 2024, and contributes to the ANZSNM Scientific & Education Committee since 2022. He is passionate about medical education and was appointed to the Royal Australasian College of Physicians Committee for Joint Clinical Training (JCT) between 2015-2019, including 2 years as National Co-ordinator of Advanced Training in Nuclear Medicine. He regularly provides post-graduate teaching presentations in both Endocrinology and Nuclear Medicine and is a regular examiner for the Nuclear Medicine Oral Assessment Task. He has significant experience with mentoring and innovative introduction of new technology, including leadership of a multidisciplinary team to implement I-124 PET/CT protocol for advanced thyroid cancer, and clinical use of other new PET tracers including [18F]PSMA-1007 & [18F]Fluorocholine.
Works
Search Professor David Pattison’s works on UQ eSpace
2018
Conference Publication
Positron Emission Tomography (PET) predictors of tumor response to Peptide Receptor Radionuclide Therapy (PRRT) in metastatic Neuroendocrine Tumors (NET)
Ladwa, R., Pattison, D., Smith, J., Goodman, S., Burge, M., Rose, S., Dowson, N. and Wyld, D. (2018). Positron Emission Tomography (PET) predictors of tumor response to Peptide Receptor Radionuclide Therapy (PRRT) in metastatic Neuroendocrine Tumors (NET). 15th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocrine Tumor Disease, Barcelona, Spain, 7-9 March 2018. Basel, Switzerland: S. Karger AG.
2018
Conference Publication
Tumor absorbed dosimetry and response of radionuclide therapy in metastatic neuroendocrine tumor
Ladwa, R., Pattison, D., Smith, J., Goodman, S., Burge, M., Rose, S., Dowson, N. and Wyld, D. (2018). Tumor absorbed dosimetry and response of radionuclide therapy in metastatic neuroendocrine tumor. 15th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocrine Tumor Disease, Barcelona, Spain, 7-9 March 2018. Basel, Switzerland: S. Karger AG.
2018
Journal Article
Localisation of occult extra-pancreatic insulinoma using glucagon-like peptide-1 receptor molecular imaging
Mossman, Anna K., Pattison, David A., Hicks, Rodney J., Hamblin, Peter S. and Yates, Christopher J. (2018). Localisation of occult extra-pancreatic insulinoma using glucagon-like peptide-1 receptor molecular imaging. Internal Medicine Journal, 48 (1), 97-98. doi: 10.1111/imj.13664
2018
Book Chapter
Management of distant metastasis in differentiated thyroid cancer
Pattison, David A., Miller, Julie A., Khavar, Bhadrakant and Tie, Jeanne (2018). Management of distant metastasis in differentiated thyroid cancer. Evidence-Based Endocrine Surgery. (pp. 121-140) Singapore: Springer Singapore. doi: 10.1007/978-981-10-1124-5_11
2017
Journal Article
Efficacy of Peptide Receptor Radionuclide Therapy for Functional Metastatic Paraganglioma and Pheochromocytoma
Kong, Grace, Grozinsky-Glasberg, Simona, Hofman, Michael S., Callahan, Jason, Meirovitz, Amichay, Maimon, Ofra, Pattison, David A., Gross, David J. and Hicks, Rodney J. (2017). Efficacy of Peptide Receptor Radionuclide Therapy for Functional Metastatic Paraganglioma and Pheochromocytoma. The Journal of Clinical Endocrinology & Metabolism, 102 (9), 3278-3287. doi: 10.1210/jc.2017-00816
2017
Conference Publication
177Lu-DOTA-OCTREOTATE PEPTIDE RECEPTOR RADIONUCLIDE THERAPY (PRRT) IN PATIENTS WITH FUNCTIONAL AND METASTATIC PHAEOCHROMOCYTOMA (PCC) OR PARAGANGLIOMA (PGL)
Kong, G., Grozinsky-Glasberg, S., Callahan, J., Hofman, M. S., Meirovitz, A., Maimon, O., Pattison, D. A., Gross, D. J. and Hicks, R. J. (2017). 177Lu-DOTA-OCTREOTATE PEPTIDE RECEPTOR RADIONUCLIDE THERAPY (PRRT) IN PATIENTS WITH FUNCTIONAL AND METASTATIC PHAEOCHROMOCYTOMA (PCC) OR PARAGANGLIOMA (PGL). HOBOKEN: WILEY.
2017
Conference Publication
USING A FORMULA BASED ON BMI AND BSL FOR ADMINISTRATION OF ACTRAPID FOR FDG-PET SCANS WHERE THE PATIENT'S BSL IS ELEVATED ON ARRIVAL
MacFarlane, L. and Pattison, D. (2017). USING A FORMULA BASED ON BMI AND BSL FOR ADMINISTRATION OF ACTRAPID FOR FDG-PET SCANS WHERE THE PATIENT'S BSL IS ELEVATED ON ARRIVAL. HOBOKEN: WILEY.
2017
Conference Publication
The management of refractory catecholamine associated symptoms in malignant phaeochromocytoma
Mossman, Anna, Pattison, David, Inchley, Fiona and Hamblin, P. Shane (2017). The management of refractory catecholamine associated symptoms in malignant phaeochromocytoma. HOBOKEN: WILEY-BLACKWELL.
2017
Conference Publication
Peptide Receptor Radionuclide Therapy (PRRT) for Treatment of Functional and Metastatic Phaeochromocytoma (PCC) and Paraganglioma (PGL)
Kong, G., Grozinsky-Glasberg, S., Callahan, J., Hofman, M., Meirovitz, A., Maimon, O., Pattison, D., Gross, D. and Hicks, R. (2017). Peptide Receptor Radionuclide Therapy (PRRT) for Treatment of Functional and Metastatic Phaeochromocytoma (PCC) and Paraganglioma (PGL). 14th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocrine Tumor Disease, Barcelona Spain, Mar 08-10, 2017. BASEL: KARGER.
2016
Journal Article
High clinical and morphologic response using 90Y-DOTA-octreotate sequenced with 177Lu-DOTA-octreotate induction peptide receptor chemoradionuclide therapy (PRCRT) for bulky neuroendocrine tumours
Kong, Grace, Callahan, Jason, Hofman, Michael S., Pattison, David A., Akhurst, Tim, Michael, Michael, Eu, Peter and Hicks, Rodney J. (2016). High clinical and morphologic response using 90Y-DOTA-octreotate sequenced with 177Lu-DOTA-octreotate induction peptide receptor chemoradionuclide therapy (PRCRT) for bulky neuroendocrine tumours. European Journal of Nuclear Medicine and Molecular Imaging, 44 (3), 476-489. doi: 10.1007/s00259-016-3527-x
2016
Journal Article
THYROPET Study: Is It Biology or Technology That Is the Issue?
Pattison, David A. and Hicks, Rodney J. (2016). THYROPET Study: Is It Biology or Technology That Is the Issue?. Journal of Nuclear Medicine, 58 (2), 354-354. doi: 10.2967/jnumed.116.181420
2016
Journal Article
68Ga-DOTATATE and 18F-FDG PET/CT in Paraganglioma and Pheochromocytoma: utility, patterns and heterogeneity
Chang, Chian A., Pattison, David A., Tothill, Richard W., Kong, Grace, Akhurst, Tim J., Hicks, Rodney J. and Hofman, Michael S. (2016). 68Ga-DOTATATE and 18F-FDG PET/CT in Paraganglioma and Pheochromocytoma: utility, patterns and heterogeneity. Cancer Imaging, 16 (1) 22. doi: 10.1186/s40644-016-0084-2
2016
Journal Article
Intense focal pituitary FDG uptake due to intravascular large B-cell lymphoma in pyrexia of unknown origin : FDG-Avid Pituitary & Intravascular Lymphoma
Pattison, David A., Hofman, Michael S., Bazargan, Ali, Colman, Peter and Hicks, Rodney J. (2016). Intense focal pituitary FDG uptake due to intravascular large B-cell lymphoma in pyrexia of unknown origin : FDG-Avid Pituitary & Intravascular Lymphoma. American Journal of Hematology, 91 (11), 1167-1168. doi: 10.1002/ajh.24469
2016
Conference Publication
PRELIMINARY RESULTS OF (68)GA EXENDIN-4 PET/CT IMAGING OF NEUROENDOCRINE TUMOURS (NETS)
Pattison, D., Kong, G., Messazos, B., Hamblin, P., Fourlanos, S., Lee, M., Michael, M., Hong, E., Eu, P. and Hicks, R. (2016). PRELIMINARY RESULTS OF (68)GA EXENDIN-4 PET/CT IMAGING OF NEUROENDOCRINE TUMOURS (NETS). HOBOKEN: WILEY-BLACKWELL.
2016
Conference Publication
HIGH EFFICACY FROM A PERSONALISED APPROACH USING Y-90-DOTA-OCTREOTATE SEQUENCED WITH (LU)-L-177-DOTA-OCTREOTATE INDUCTION PEPTIDE RECEPTOR CHEMORADIONUCLIDE THERAPY (PRCRT) FOR BULKY NEUROENDOCRINE TUMOURS
Kong, G., Callahan, J., Hofman, M., Pattison, D., Akhurst, T., Michael, M., Eu, P. and Hicks, R. (2016). HIGH EFFICACY FROM A PERSONALISED APPROACH USING Y-90-DOTA-OCTREOTATE SEQUENCED WITH (LU)-L-177-DOTA-OCTREOTATE INDUCTION PEPTIDE RECEPTOR CHEMORADIONUCLIDE THERAPY (PRCRT) FOR BULKY NEUROENDOCRINE TUMOURS. HOBOKEN: WILEY-BLACKWELL.
2016
Journal Article
A New Theranostic Paradigm for Advanced Thyroid Cancer
Pattison, David A., Solomon, Benjamin and Hicks, Rodney J. (2016). A New Theranostic Paradigm for Advanced Thyroid Cancer. Journal of Nuclear Medicine, 57 (10), 1493-1494. doi: 10.2967/jnumed.116.173534
2016
Conference Publication
Favourable responses in Patients with Bulky Neuroendocrine Tumours (NET) A Personalised Approach Using 90Y-DOTA-Octreotate Sequenced with 177Lu-DOTA-Octreotate Induction Peptide Receptor Chemoradionuclide Therapy (PRCRT)
Kong, G., Callahan, J., Hofman, M., Pattison, D., Akhurst, T., Michael, M., Eu, P. and Hicks, R. (2016). Favourable responses in Patients with Bulky Neuroendocrine Tumours (NET) A Personalised Approach Using 90Y-DOTA-Octreotate Sequenced with 177Lu-DOTA-Octreotate Induction Peptide Receptor Chemoradionuclide Therapy (PRCRT). 13th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocrine Tumor Disease, Barcelona Spain, Mar 09-11, 2016. BASEL: KARGER.
2015
Conference Publication
MANAGEMENT OF HYPERTENSIVE CRISIS IN PARAGANGLIOMA-A CASE REPORT
Jackson, Cheryl, Lingaratnam, Senthil, Michael, Michael and Pattison, David (2015). MANAGEMENT OF HYPERTENSIVE CRISIS IN PARAGANGLIOMA-A CASE REPORT. HOBOKEN: WILEY-BLACKWELL.
2015
Journal Article
Role of Fluorodeoxyglucose PET/Computed Tomography in Targeted Radionuclide Therapy for Endocrine Malignancies
Pattison, David A. and Hofman, Michael S. (2015). Role of Fluorodeoxyglucose PET/Computed Tomography in Targeted Radionuclide Therapy for Endocrine Malignancies. PET Clinics, 10 (4), 461-476. doi: 10.1016/j.cpet.2015.05.005
2015
Conference Publication
GA-68 DOTA-OCTREOTATE (GATATE) AND F-18 FLUORODEOXYGLUCOSE (FDG) PET/CT IN THE ASSESSMENT OF PARAGANGLIOMAS AND PHEOCHROMOCYTOMAS
Chang, C. A., Hofman, M., Thompson, M., Pattison, D. and Hicks, R. (2015). GA-68 DOTA-OCTREOTATE (GATATE) AND F-18 FLUORODEOXYGLUCOSE (FDG) PET/CT IN THE ASSESSMENT OF PARAGANGLIOMAS AND PHEOCHROMOCYTOMAS. HOBOKEN: WILEY-BLACKWELL.
Funding
Past funding
Supervision
Availability
- Professor David Pattison is:
- Not available for supervision
Supervision history
Current supervision
-
Doctor Philosophy
PARA-PET: a randomised trial of [18F]FCH vs conventional imaging for primary hyperparathyroidism
Principal Advisor
Other advisors: Professor Roslyn Francis
Completed supervision
-
2024
Master Philosophy
21st Century Approaches for Imaging and Genetic Testing for Phaeochromocytomas and Paragangliomas
Principal Advisor
-
2020
Master Philosophy
Predictors of dosimetry and outcome to peptide receptor radionuclide therapy in metastatic neuroendocrine tumour.
Associate Advisor
Other advisors: Associate Professor David Wyld
Media
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