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Associate Professor David Pattison
Associate Professor

David Pattison

Email: 

Overview

Background

  • Director, Department of Nuclear Medicine & PET Services, Royal Brisbane & Women’s Hospital
  • Theranostics Lead, Department of Nuclear Medicine & Specialised PET Services, Royal Brisbane & Women's Hospital
  • Co-Director of Training, Department of Nuclear Medicine & Specialised PET Services, Royal Brisbane & Women’s Hospital
  • Associate Professor, School of Medicine, University of Queensland

David underwent dual specialty training in both Endocrinology and Nuclear Medicine at Royal Melbourne Hospital, Austin Hospital and Peter MacCallum Cancer Centre in Melbourne. He was appointed a staff specialist at Peter MacCallum Cancer Centre at the completion of his training, where he continued to gain experience in a quaternary referral centre for theranostics treating patients from across south-east Australia and New Zealand. In 2016 he moved to Royal Brisbane & Women’s Hospital where he is currently the Director of Department of Nuclear Medicine & PET Services and nuclear medicine lead for the RBWH radionuclide therapy service.

Availability

Associate Professor David Pattison is:
Available for supervision

Qualifications

  • Bachelor (Honours) of Medicine Surgery, University of Melbourne
  • Masters (Coursework) of Public Health, James Cook University
  • Royal Australasian College of Physicians, Royal Australasian College of Physicians

Research impacts

David’s major research areas are at the intersection of his two medical specialties – Nuclear Medicine and Endocrinology – with a focus on theranostics for neuroendocrine tumours, thyroid cancer and prostate cancer, in addition to PET imaging of other malignancies. He has been a chief investigator on numerous competitive grants for theranostics, including neuroendocrine tumours (STOPNET $1.25 million MRFF 2024), Australian Research Network for Translation of Targeted Alpha Therapies ($9.76 million MRFF 2022), redifferentiation of radioactive iodine refractory thyroid cancer (I-FIRST $2.7 million MRFF 2021) and prostate cancer (UpFrontPSMA $4 million Movember/Cancer Australia 2019).

David has published 63 peer-reviewed papers, 3 book chapters and over 50 conference abstracts. A/Prof Pattison has delivered 37 invited speaker presentations in the past 5 years. He has been a Principal investigator of numerous prospective theranostics clinical trials, including TheraP, the first randomised controlled trial of [177Lu]Lu-PSMA-617 for metastatic castrate resistant prostate cancer, UpFrontPSMA, ENZA-P and I-FIRST and lead an Australian-first prospective PET imaging trials evaluating [18F]PSMA-1007. He is a member of Australia and New Zealand Urogenital & Prostate (ANZUP) Cancer Trials Group and Australasian Gastro-Intestinal Trials Group (AGITG), and sits on various national trial Management Committees.

David has a prominent national / international profile and professional involvement. Internationally, he sits on the Thyroid and Head and Neck Cancer (THANC) Foundation Medical Advisory Board for Thyroid International Recommendations Online, as the Committee lead for the section on the role of radioactive iodine in diagnostics and therapeutics. Nationally, he is a Board Director for the Australasian Association of Nuclear Medicine Specialists (AANMS) and sits on the AANMS Training Site Advisory Committee and also Theranostics Committee. He was Deputy Chair of the AANMS working group that developed national guidelines for best practice of theranostics in Australia. He is Chair of the Australian Nuclear Science and Technology Organisation (ANSTO) Lutetitium Working Group and is co-author of the Neuroendocrine Tumour Imaging section of the current Clinical Oncology Society of Australia (COSA) Guidelines. He has sat on various national Medical Advisory Boards and the Herston Imaging Research Facility Research Advisory Group, and was the inaugral Chair of the Department of Nuclear Medicine & Specalised PET Services Research Committee. He is a regular reviewer for 10 national and international medical journals in nuclear medicine and endocrinology.

David is enthusiastic about training and mentoring of clinicians, and supervises postgraduate students (University of Queensland) in addition to nuclear medicine advanced trainees (Director of Nuclear Medicine Training at RBWH). As inaugral Chair of the AANMS Theranostics Course & Case Library Committee he convened the successful AANMS Theranostics Course in 2022 and 2024, and contributes to the ANZSNM Scientific & Education Committee since 2022. He is passionate about medical education and was appointed to the Royal Australasian College of Physicians Committee for Joint Clinical Training (JCT) between 2015-2019, including 2 years as National Co-ordinator of Advanced Training in Nuclear Medicine. He regularly provides post-graduate teaching presentations in both Endocrinology and Nuclear Medicine and is a regular examiner for the Nuclear Medicine Oral Assessment Task. He has significant experience with mentoring and innovative introduction of new technology, including leadership of a multidisciplinary team to implement I-124 PET/CT protocol for advanced thyroid cancer, and clinical use of other new PET tracers including [18F]PSMA-1007 & [18F]Fluorocholine.

Works

Search Professor David Pattison’s works on UQ eSpace

108 works between 2008 and 2025

61 - 80 of 108 works

2020

Journal Article

68Ga-PSMA PET/CT tumour intensity pre-operatively predicts adverse pathological outcomes and progression-free survival in localised prostate cancer

Roberts, Matthew J., Morton, Andrew, Donato, Peter, Kyle, Samuel, Pattison, David A., Thomas, Paul, Coughlin, Geoff, Esler, Rachel, Dunglison, Nigel, Gardiner, Robert A., Doi, Suhail A., Emmett, Louise and Yaxley, John (2020). 68Ga-PSMA PET/CT tumour intensity pre-operatively predicts adverse pathological outcomes and progression-free survival in localised prostate cancer. European Journal of Nuclear Medicine and Molecular Imaging, 48 (2), 655-656. doi: 10.1007/s00259-020-04944-2

68Ga-PSMA PET/CT tumour intensity pre-operatively predicts adverse pathological outcomes and progression-free survival in localised prostate cancer

2020

Journal Article

Long-term follow-up and outcomes of retreatment in an expanded 50-patient single-center phase II prospective trial of 177Lu-PSMA-617 theranostics in metastatic castration-resistant prostate cancer

Violet, John, Sandhu, Shahneen, Iravani, Amir, Ferdinandus, Justin, Sue-Ping Thang, , Kong, Grace, Kumar, Aravind Ravi, Akhurst, Tim, Pattison, David, Beaulieu, Alexis, Mooi, Jennifer, Tran, Ben, Guo, Christina, Kalff, Victor, Murphy, Declan G., Jackson, Price, Eu, Peter, Scalzo, Mark, Williams, Scott G., Hicks, Rod J., Hofman, Michael S. and Tran, Ben (2020). Long-term follow-up and outcomes of retreatment in an expanded 50-patient single-center phase II prospective trial of 177Lu-PSMA-617 theranostics in metastatic castration-resistant prostate cancer. Journal of Nuclear Medicine, 61 (6), 857-865. doi: 10.2967/jnumed.119.236414

Long-term follow-up and outcomes of retreatment in an expanded 50-patient single-center phase II prospective trial of 177Lu-PSMA-617 theranostics in metastatic castration-resistant prostate cancer

2020

Journal Article

Re: Long Term Follow-Up and Outcomes of Re-Treatment in an Expanded 50 Patient Single-Center Phase II Prospective Trial of Lutetium-177 (177Lu) PSMA-617 Theranostics in Metastatic Castrate-Resistant Prostate Cancer

Violet, J., Sandhu, S., Iravani, A., Ferdinandus, J., Thang, S. P., Kong, G., Kumar, A. Ravi, Akhurst, T., Pattison, D. A., Beaulieu, A., Mooi, J., Guo, C., Kalff, V., Murphy, D. G., Jackson, P., Eu, P., Scalzo, M., Williams, S., Hicks, R. J. and Hofman, M. S. (2020). Re: Long Term Follow-Up and Outcomes of Re-Treatment in an Expanded 50 Patient Single-Center Phase II Prospective Trial of Lutetium-177 (177Lu) PSMA-617 Theranostics in Metastatic Castrate-Resistant Prostate Cancer. Journal of Urology, 203 (5). doi: 10.1097/JU.0000000000000779.01

Re: Long Term Follow-Up and Outcomes of Re-Treatment in an Expanded 50 Patient Single-Center Phase II Prospective Trial of Lutetium-177 (177Lu) PSMA-617 Theranostics in Metastatic Castrate-Resistant Prostate Cancer

2019

Conference Publication

Combination of avelumabwith peptide receptor radionuclide therapy (PRRT) or conventional fractionated radiotherapy (RT) in metastatic merkel cell carcinoma (mMCC) [GoTHAM study]

Sandhu, Shahneen, Tothill, Richard, Scolyer, Richard, Guminski, Alexander, Becker, Juergen, Poulsen, Michael, Atkinson, Victoria, Neeson, Paul, Shackleton, Mark, Pattison, David, Williams, Narelle and Paton, Elizabeth (2019). Combination of avelumabwith peptide receptor radionuclide therapy (PRRT) or conventional fractionated radiotherapy (RT) in metastatic merkel cell carcinoma (mMCC) [GoTHAM study]. COSA's 46th Annual Scientific Meeting, Urological cancer; Age and gender in cancer practice; Digital health in cancer, Adelaide, SA, Australia, 12–14 November 2019. Hoboken, NJ, United States: Wiley.

Combination of avelumabwith peptide receptor radionuclide therapy (PRRT) or conventional fractionated radiotherapy (RT) in metastatic merkel cell carcinoma (mMCC) [GoTHAM study]

2019

Conference Publication

A prospective intra-individual blinded comparison of 18F-PSMA-1007 and 68GA-PSMA-11 PET/CT imaging in patients with confirmed prostate cancer

Debowski, M., Gulhane, B., Ramsay, S. C., Thomas, P. A., Garcia, P., Latter, M., Tapper, S. and Pattison, D. A. (2019). A prospective intra-individual blinded comparison of 18F-PSMA-1007 and 68GA-PSMA-11 PET/CT imaging in patients with confirmed prostate cancer. Australian and New Zealand Society of Nuclear Medicine (ANZSNM) 49th ASM, Adelaide, SA, Australia, 26–28 April 2019. Hoboken, NJ, United States: Wiley.

A prospective intra-individual blinded comparison of 18F-PSMA-1007 and 68GA-PSMA-11 PET/CT imaging in patients with confirmed prostate cancer

2018

Conference Publication

Targeted Molecular Imaging of Translocator Protein (TSPO) Using (18F)GE180-PET for the Diagnosis of Gastrointestinal Graft Versus host Disease (GI-GVHD)

Scott, Ashleigh P., Tey, Siok-Keen, Thomas, Paul, Pattison, David and Kennedy, Glen A. (2018). Targeted Molecular Imaging of Translocator Protein (TSPO) Using (18F)GE180-PET for the Diagnosis of Gastrointestinal Graft Versus host Disease (GI-GVHD). 60th Annual Meeting of the American Society of Hematology (ASH), San Diego, CA United States, 1-4 December 2018. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2018-99-114114

Targeted Molecular Imaging of Translocator Protein (TSPO) Using (18F)GE180-PET for the Diagnosis of Gastrointestinal Graft Versus host Disease (GI-GVHD)

2018

Journal Article

64Cu-SARTATE PET imaging of patients with neuroendocrine tumors demonstrates high tumor uptake and retention, potentially allowing prospective dosimetry for peptide receptor radionuclide therapy

Hicks, Rodney J., Jackson, Price, Kong, Grace, Ware, Robert E., Hofman, Michael S., Pattison, David A., Akhurst, Timothy A., Drummond, Elizabeth, Roselt, Peter, Callahan, Jason, Price, Roger, Jeffery, Charmaine M., Hong, Emily, Noonan, Wayne, Herschtal, Alan, Hicks, Lauren J., Hedt, Amos, Harris, Matthew, Paterson, Brett M. and Donnelly, Paul S. (2018). 64Cu-SARTATE PET imaging of patients with neuroendocrine tumors demonstrates high tumor uptake and retention, potentially allowing prospective dosimetry for peptide receptor radionuclide therapy. Journal of Nuclear Medicine, 60 (6), 777-785. doi: 10.2967/jnumed.118.217745

64Cu-SARTATE PET imaging of patients with neuroendocrine tumors demonstrates high tumor uptake and retention, potentially allowing prospective dosimetry for peptide receptor radionuclide therapy

2018

Journal Article

Lymphangitic carcinomatosis from prostate cancer identified with gallium-68 prostate-specific membrane antigen positron emission tomography imaging

Tang, Victor, Campbell, Patrina and Pattison, David A. (2018). Lymphangitic carcinomatosis from prostate cancer identified with gallium-68 prostate-specific membrane antigen positron emission tomography imaging. Urology, 114, e1-e2. doi: 10.1016/j.urology.2017.12.010

Lymphangitic carcinomatosis from prostate cancer identified with gallium-68 prostate-specific membrane antigen positron emission tomography imaging

2018

Conference Publication

(18)FDG PET/CT CARDIAC SARCOID IMAGING: MONITORING KETONE LEVELS TO AVOID INADEQUATE SUPPRESSION OF PHYSIOLOGIC MYOCARDIAL UPTAKE

Robinson, B., Pattison, D. and Lee, K. (2018). (18)FDG PET/CT CARDIAC SARCOID IMAGING: MONITORING KETONE LEVELS TO AVOID INADEQUATE SUPPRESSION OF PHYSIOLOGIC MYOCARDIAL UPTAKE. HOBOKEN: WILEY.

(18)FDG PET/CT CARDIAC SARCOID IMAGING: MONITORING KETONE LEVELS TO AVOID INADEQUATE SUPPRESSION OF PHYSIOLOGIC MYOCARDIAL UPTAKE

2018

Journal Article

Diagnostic challenges in a patient with an occult insulinoma:68 Ga-DOTA-exendin-4 PET/CT and68Ga-DOTATATE PET/CT

Bongetti, Elisa, Lee, Melissa H., Pattison, David A., Hicks, Rodney J., Norris, Richard, Sachithanandan, Nirupa and MacIsaac, Richard J. (2018). Diagnostic challenges in a patient with an occult insulinoma:68 Ga-DOTA-exendin-4 PET/CT and68Ga-DOTATATE PET/CT. Clinical Case Reports, 6 (4), 719-722. doi: 10.1002/ccr3.1448

Diagnostic challenges in a patient with an occult insulinoma:68 Ga-DOTA-exendin-4 PET/CT and68Ga-DOTATATE PET/CT

2018

Journal Article

Tumor cystic necrosis following peptide receptor radionuclide therapy in neuroendocrine tumors

Ladwa, Rahul, Wen Hong, Hooi, Wyld, David, Pattison, David A. and Burge, Matthew (2018). Tumor cystic necrosis following peptide receptor radionuclide therapy in neuroendocrine tumors. Clinical Nuclear Medicine, 43 (3), 186-187. doi: 10.1097/RLU.0000000000001970

Tumor cystic necrosis following peptide receptor radionuclide therapy in neuroendocrine tumors

2018

Conference Publication

Pretherapeutic predictors of tumor absorbed dosimetry in radionuclide therapy for metastatic neuroendocrine tumors

Ladwa, R., Pattison, D., Smith, J., Goodman, S., Burg, M., Rose, S., Dowson, N. and Wyld, D. (2018). Pretherapeutic predictors of tumor absorbed dosimetry in radionuclide therapy for metastatic neuroendocrine tumors. 15th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocrine Tumor Disease, Barcelona, Spain, 7-9 March 2018. Basel, Switzerland: S. Karger AG.

Pretherapeutic predictors of tumor absorbed dosimetry in radionuclide therapy for metastatic neuroendocrine tumors

2018

Conference Publication

Validation of Abbreviated 177Lu-DOTATATE Renal and Lesional Dosimetry Protocol using Quantitative SPECT

Goodman, Steven , Patford, Shaun , Ladwa, Rahul , Smith, Jye , Wyld, David and Pattison, David A. (2018). Validation of Abbreviated 177Lu-DOTATATE Renal and Lesional Dosimetry Protocol using Quantitative SPECT. 12th Congress of the World Federation of Nuclear Medicine and Biology., Melbourne Australia, 20-24 April 2018.

Validation of Abbreviated 177Lu-DOTATATE Renal and Lesional Dosimetry Protocol using Quantitative SPECT

2018

Conference Publication

Positron Emission Tomography (PET) predictors of tumor response to Peptide Receptor Radionuclide Therapy (PRRT) in metastatic Neuroendocrine Tumors (NET)

Ladwa, R., Pattison, D., Smith, J., Goodman, S., Burge, M., Rose, S., Dowson, N. and Wyld, D. (2018). Positron Emission Tomography (PET) predictors of tumor response to Peptide Receptor Radionuclide Therapy (PRRT) in metastatic Neuroendocrine Tumors (NET). 15th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocrine Tumor Disease, Barcelona, Spain, 7-9 March 2018. Basel, Switzerland: S. Karger AG.

Positron Emission Tomography (PET) predictors of tumor response to Peptide Receptor Radionuclide Therapy (PRRT) in metastatic Neuroendocrine Tumors (NET)

2018

Conference Publication

Tumor absorbed dosimetry and response of radionuclide therapy in metastatic neuroendocrine tumor

Ladwa, R., Pattison, D., Smith, J., Goodman, S., Burge, M., Rose, S., Dowson, N. and Wyld, D. (2018). Tumor absorbed dosimetry and response of radionuclide therapy in metastatic neuroendocrine tumor. 15th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocrine Tumor Disease, Barcelona, Spain, 7-9 March 2018. Basel, Switzerland: S. Karger AG.

Tumor absorbed dosimetry and response of radionuclide therapy in metastatic neuroendocrine tumor

2018

Journal Article

Localisation of occult extra-pancreatic insulinoma using glucagon-like peptide-1 receptor molecular imaging

Mossman, Anna K., Pattison, David A., Hicks, Rodney J., Hamblin, Peter S. and Yates, Christopher J. (2018). Localisation of occult extra-pancreatic insulinoma using glucagon-like peptide-1 receptor molecular imaging. Internal Medicine Journal, 48 (1), 97-98. doi: 10.1111/imj.13664

Localisation of occult extra-pancreatic insulinoma using glucagon-like peptide-1 receptor molecular imaging

2018

Book Chapter

Management of distant metastasis in differentiated thyroid cancer

Pattison, David A., Miller, Julie A., Khavar, Bhadrakant and Tie, Jeanne (2018). Management of distant metastasis in differentiated thyroid cancer. Evidence-Based Endocrine Surgery. (pp. 121-140) Singapore: Springer Singapore. doi: 10.1007/978-981-10-1124-5_11

Management of distant metastasis in differentiated thyroid cancer

2017

Journal Article

Efficacy of Peptide Receptor Radionuclide Therapy for Functional Metastatic Paraganglioma and Pheochromocytoma

Kong, Grace, Grozinsky-Glasberg, Simona, Hofman, Michael S., Callahan, Jason, Meirovitz, Amichay, Maimon, Ofra, Pattison, David A., Gross, David J. and Hicks, Rodney J. (2017). Efficacy of Peptide Receptor Radionuclide Therapy for Functional Metastatic Paraganglioma and Pheochromocytoma. The Journal of Clinical Endocrinology & Metabolism, 102 (9), 3278-3287. doi: 10.1210/jc.2017-00816

Efficacy of Peptide Receptor Radionuclide Therapy for Functional Metastatic Paraganglioma and Pheochromocytoma

2017

Conference Publication

177Lu-DOTA-OCTREOTATE PEPTIDE RECEPTOR RADIONUCLIDE THERAPY (PRRT) IN PATIENTS WITH FUNCTIONAL AND METASTATIC PHAEOCHROMOCYTOMA (PCC) OR PARAGANGLIOMA (PGL)

Kong, G., Grozinsky-Glasberg, S., Callahan, J., Hofman, M. S., Meirovitz, A., Maimon, O., Pattison, D. A., Gross, D. J. and Hicks, R. J. (2017). 177Lu-DOTA-OCTREOTATE PEPTIDE RECEPTOR RADIONUCLIDE THERAPY (PRRT) IN PATIENTS WITH FUNCTIONAL AND METASTATIC PHAEOCHROMOCYTOMA (PCC) OR PARAGANGLIOMA (PGL). HOBOKEN: WILEY.

177Lu-DOTA-OCTREOTATE PEPTIDE RECEPTOR RADIONUCLIDE THERAPY (PRRT) IN PATIENTS WITH FUNCTIONAL AND METASTATIC PHAEOCHROMOCYTOMA (PCC) OR PARAGANGLIOMA (PGL)

2017

Conference Publication

USING A FORMULA BASED ON BMI AND BSL FOR ADMINISTRATION OF ACTRAPID FOR FDG-PET SCANS WHERE THE PATIENT'S BSL IS ELEVATED ON ARRIVAL

MacFarlane, L. and Pattison, D. (2017). USING A FORMULA BASED ON BMI AND BSL FOR ADMINISTRATION OF ACTRAPID FOR FDG-PET SCANS WHERE THE PATIENT'S BSL IS ELEVATED ON ARRIVAL. HOBOKEN: WILEY.

USING A FORMULA BASED ON BMI AND BSL FOR ADMINISTRATION OF ACTRAPID FOR FDG-PET SCANS WHERE THE PATIENT'S BSL IS ELEVATED ON ARRIVAL

Funding

Past funding

  • 2021
    Staging of aggressive prostate cancer 'invisible' to PSMA-PET: The FDG-PET for INvisible Disease (FIND) Trial
    Metro North Hospital and Health Service
    Open grant

Supervision

Availability

Associate Professor David Pattison is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    PARA-PET: a randomised trial of [18F]FCH vs conventional imaging for primary hyperparathyroidism

    Principal Advisor

Completed supervision

Media

Enquiries

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