Dr Lotten Ragnarsson
Dr

Lotten Ragnarsson

Email: 
Phone: 
+61 7 334 62722

Availability

Dr Lotten Ragnarsson is:
Available for supervision

Fields of research

Neurosciences

Qualifications

  • Masters (Research) of Science, University of Kalmar
  • Licentiate of Immunology, University of Uppsala
  • Doctor of Philosophy of Biochemistry and Molecular Biology, The University of Queensland

Search Professor Lotten Ragnarsson’s works on UQ eSpace

52 works between 1998 and 2024
All (52) Journal Article (34) Book Chapter (3) Conference Publication (15)

1 - 20 of 52 works

2024

Journal Article

Novel scorpion toxin ω-Buthitoxin-Hf1a selectively inhibits calcium influx via CaV3.3 and CaV3.2 and alleviates allodynia in a mouse model of acute postsurgical pain

Wang, Dan, Herzig, Volker, Dekan, Zoltan, Rosengren, K. Johan, Payne, Colton D., Hasan, Md. Mahadhi, Zhuang, Jiajie, Bourinet, Emmanuel, Ragnarsson, Lotten, Alewood, Paul F. and Lewis, Richard J. (2024). Novel scorpion toxin ω-Buthitoxin-Hf1a selectively inhibits calcium influx via CaV3.3 and CaV3.2 and alleviates allodynia in a mouse model of acute postsurgical pain. International Journal of Molecular Sciences, 25 (9) 4745, 4745. doi: 10.3390/ijms25094745

Novel scorpion toxin ω-Buthitoxin-Hf1a selectively inhibits calcium influx via CaV3.3 and CaV3.2 and alleviates allodynia in a mouse model of acute postsurgical pain

2024

Journal Article

Erythromelalgia caused by the missense mutation p.Arg220Pro in an alternatively spliced exon of SCN9A (NaV1.7)

Deuis, Jennifer R., Kumble, Smitha, Keramidas, Angelo, Ragnarsson, Lotten, Simons, Cas, Pais, Lynn, White, Susan M and Vetter, Irina (2024). Erythromelalgia caused by the missense mutation p.Arg220Pro in an alternatively spliced exon of SCN9A (NaV1.7). Human Molecular Genetics, 33 (2), 103-109. doi: 10.1093/hmg/ddad152

Erythromelalgia caused by the missense mutation p.Arg220Pro in an alternatively spliced exon of SCN9A (NaV1.7)

2023

Journal Article

GRIN1 variants associated with neurodevelopmental disorders reveal channel gating pathomechanisms

Ragnarsson, Lotten, Zhang, Zihan, Das, Sooraj S., Tran, Poanna, Andersson, Åsa, Portes, Vincent Des, Demestre, Cecilia Altuzzara, Remerand, Ganaelle, Labalme, Audrey, Chatron, Nicolas, Sanlaville, Damien, Lesca, Gaetan, Anggono, Victor, Vetter, Irina and Keramidas, Angelo (2023). GRIN1 variants associated with neurodevelopmental disorders reveal channel gating pathomechanisms. Epilepsia, 64 (12), 3377-3388. doi: 10.1111/epi.17776

GRIN1 variants associated with neurodevelopmental disorders reveal channel gating pathomechanisms

2023

Journal Article

Structural conformation and activity of spider-derived inhibitory cystine knot peptide Pn3a are modulated by pH

Tran, Poanna, Crawford, Theo, Ragnarsson, Lotten, Deuis, Jennifer R., Mobli, Mehdi, Sharpe, Simon J., Schroeder, Christina I. and Vetter, Irina (2023). Structural conformation and activity of spider-derived inhibitory cystine knot peptide Pn3a are modulated by pH. ACS Omega, 8 (29), 26276-26286. doi: 10.1021/acsomega.3c02664

Structural conformation and activity of spider-derived inhibitory cystine knot peptide Pn3a are modulated by pH

2023

Journal Article

Changes in potency and subtype selectivity of bivalent NaV toxins are knot-specific

Tran, Poanna, Tran, Hue N. T., McMahon, Kirsten L., Deuis, Jennifer R., Ragnarsson, Lotten, Norman, Alexander, Sharpe, Simon J., Payne, Richard J., Vetter, Irina and Schroeder, Christina I. (2023). Changes in potency and subtype selectivity of bivalent NaV toxins are knot-specific. Bioconjugate Chemistry, 34 (6), 1072-1083. doi: 10.1021/acs.bioconjchem.3c00135

Changes in potency and subtype selectivity of bivalent NaV toxins are knot-specific

2023

Journal Article

Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function

Jami, Sina, Deuis, Jennifer R., Klasfauseweh, Tabea, Cheng, Xiaoyang, Kurdyukov, Sergey, Chung, Felicity, Okorokov, Andrei L., Li, Shengnan, Zhang, Jiangtao, Cristofori-Armstrong, Ben, Israel, Mathilde R., Ju, Robert J., Robinson, Samuel D., Zhao, Peng, Ragnarsson, Lotten, Andersson, Åsa, Tran, Poanna, Schendel, Vanessa, McMahon, Kirsten L., Tran, Hue N. T., Chin, Yanni K.-Y., Zhu, Yifei, Liu, Junyu, Crawford, Theo, Purushothamvasan, Saipriyaa, Habib, Abdella M., Andersson, David A., Rash, Lachlan D., Wood, John N. ... Vetter, Irina (2023). Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function. Nature Communications, 14 (1) 2442. doi: 10.1038/s41467-023-37963-2

Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function

2023

Book Chapter

Role of Ionotropic Glutamate receptors in neurodegenerative and other disorders

Ragnarsson, Lotten, Dodd, Peter R. and Latif, Matthew R. (2023). Role of Ionotropic Glutamate receptors in neurodegenerative and other disorders. Handbook of neurotoxicity. (pp. 1969-1997) edited by Richard M. Kostrzewa. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-031-15080-7_144

Role of Ionotropic Glutamate receptors in neurodegenerative and other disorders

2022

Journal Article

Neurotoxic and cytotoxic peptides underlie the painful stings of the tree nettle Urtica ferox

Xie, Jing, Robinson, Samuel D., Gilding, Edward K., Jami, Sina, Deuis, Jennifer R., Rehm, Fabian B.H., Yap, Kuok, Ragnarsson, Lotten, Chan, Lai Yue, Hamilton, Brett R., Harvey, Peta J., Craik, David J., Vetter, Irina and Durek, Thomas (2022). Neurotoxic and cytotoxic peptides underlie the painful stings of the tree nettle Urtica ferox. Journal of Biological Chemistry, 298 (8) 102218, 1-12. doi: 10.1016/j.jbc.2022.102218

Neurotoxic and cytotoxic peptides underlie the painful stings of the tree nettle Urtica ferox

2022

Journal Article

Diindolylmethane derivatives: new selective blockers for T-type calcium channels

Wang, Dan, Neupane, Pratik, Ragnarsson, Lotten, Capon, Robert and Lewis, Richard (2022). Diindolylmethane derivatives: new selective blockers for T-type calcium channels. Membranes, 12 (8) 749, 1-13. doi: 10.3390/membranes12080749

Diindolylmethane derivatives: new selective blockers for T-type calcium channels

2022

Journal Article

The structural conformation of the tachykinin domain drives the anti‐tumoral activity of an octopus peptide in melanoma BRAF <sup>V600E</sup>

Moral‐Sanz, Javier, Fernandez‐Rojo, Manuel A., Colmenarejo, Gonzalo, Kurdyukov, Sergey, Brust, Andreas, Ragnarsson, Lotten, Andersson, Åsa, Vila, Sabela F., Cabezas‐Sainz, Pablo, Wilhelm, Patrick, Vela‐Sebastian, Ana, Fernández‐Carrasco, Isabel, Chin, Yanni K. Y., López‐ Mancheño, Yaiza, Smallwood, Taylor B., Clark, Richard J., Fry, Bryan G., King, Glenn F., Ramm, Grant A., Alewood, Paul F., Lewis, Richard J., Mulvenna, Jason P., Boyle, Glen M., Sanchez, Laura E., Neely, G. Gregory, Miles, John J. and Ikonomopoulou, Maria P. (2022). The structural conformation of the tachykinin domain drives the anti‐tumoral activity of an octopus peptide in melanoma BRAF V600E. British Journal of Pharmacology, 179 (20), 4878-4896. doi: 10.1111/bph.15923

The structural conformation of the tachykinin domain drives the anti‐tumoral activity of an octopus peptide in melanoma BRAF <sup>V600E</sup>

2022

Journal Article

Low potency inhibition of NaV1.7 by externally applied QX-314 via a depolarizing shift in the voltage-dependence of activation

Klasfauseweh, Tabea, Israel, Mathilde R., Ragnarsson, Lotten, Cox, James J., Durek, Thomas, Carter, David A., Leffler, Andreas, Vetter, Irina and Deuis, Jennifer R. (2022). Low potency inhibition of NaV1.7 by externally applied QX-314 via a depolarizing shift in the voltage-dependence of activation. European Journal of Pharmacology, 925 175013, 175013. doi: 10.1016/j.ejphar.2022.175013

Low potency inhibition of NaV1.7 by externally applied QX-314 via a depolarizing shift in the voltage-dependence of activation

2022

Journal Article

The tarantula venom peptide Eo1a binds to the domain II S3-S4 extracellular loop of voltage-gated sodium channel NaV1.8 to enhance activation

Deuis, Jennifer R., Ragnarsson, Lotten, Robinson, Samuel D., Dekan, Zoltan, Chan, Lerena, Jin, Ai-Hua, Tran, Poanna, McMahon, Kirsten L., Li, Shengnan, Wood, John N., Cox, James J., King, Glenn F., Herzig, Volker and Vetter, Irina (2022). The tarantula venom peptide Eo1a binds to the domain II S3-S4 extracellular loop of voltage-gated sodium channel NaV1.8 to enhance activation. Frontiers in Pharmacology, 12 789570, 789570. doi: 10.3389/fphar.2021.789570

The tarantula venom peptide Eo1a binds to the domain II S3-S4 extracellular loop of voltage-gated sodium channel NaV1.8 to enhance activation

2021

Journal Article

Transfection methods for high-throughput cellular assays of voltage-gated calcium and sodium channels involved in pain

Hasan, Md. Mahadhi, Ragnarsson, Lotten, Cardoso, Fernanda C. and Lewis, Richard J. (2021). Transfection methods for high-throughput cellular assays of voltage-gated calcium and sodium channels involved in pain. PLOS ONE, 16 (3) e0243645, e0243645. doi: 10.1371/journal.pone.0243645

Transfection methods for high-throughput cellular assays of voltage-gated calcium and sodium channels involved in pain

2021

Conference Publication

Subcutaneous analgesic actions and mode of action of binding of ω-conotoxins at Cav2.2

Hasan, Mahadhi, Abraham, Nikita, Cardoso, Fernanda C., Ragnarsson, Lotten, Starobova, Hana, Mueller, Alexander, Vetter, Irina and Lewis, Richard J. (2021). Subcutaneous analgesic actions and mode of action of binding of ω-conotoxins at Cav2.2. Venom to Drugs, Daydream Island, QLD Australia, 15 - 19 March 2021.

Subcutaneous analgesic actions and mode of action of binding of ω-conotoxins at Cav2.2

2020

Journal Article

Characterisation of δ-Conotoxin TxVIA as a mammalian T-type calcium channel modulator

Wang, Dan, Himaya, S.W.A., Giacomotto, Jean, Hasan, Md. Mahadhi, Cardoso, Fernanda C., Ragnarsson, Lotten and Lewis, Richard J. (2020). Characterisation of δ-Conotoxin TxVIA as a mammalian T-type calcium channel modulator. Marine Drugs, 18 (7) 343, 1-13. doi: 10.3390/md18070343

Characterisation of δ-Conotoxin TxVIA as a mammalian T-type calcium channel modulator

2020

Journal Article

Structure and allosteric activity of a single-disulfide conopeptide from Conus zonatus at human α3β4 and α7 nicotinic acetylcholine receptors

Mohan, Madhan Kumar, Abraham, Nikita, Rajesh, R. P., Jayaseelan, Benjamin Franklin, Ragnarsson, Lotten, Lewis, Richard J. and Sarma, Siddhartha P. (2020). Structure and allosteric activity of a single-disulfide conopeptide from Conus zonatus at human α3β4 and α7 nicotinic acetylcholine receptors. Journal of Biological Chemistry, 295 (20), 7096-7112. doi: 10.1074/jbc.RA119.012098

Structure and allosteric activity of a single-disulfide conopeptide from Conus zonatus at human α3β4 and α7 nicotinic acetylcholine receptors

2020

Journal Article

Synthesis, pharmacological and structural characterization of novel conopressins from Conus miliaris

Giribaldi, Julien, Ragnarsson, Lotten, Pujante, Tom, Enjalbal, Christine, Wilson, David, Daly, Norelle L., Lewis, Richard J. and Dutertre, Sebastien (2020). Synthesis, pharmacological and structural characterization of novel conopressins from Conus miliaris. Marine Drugs, 18 (3) md18030150, 150. doi: 10.3390/md18030150

Synthesis, pharmacological and structural characterization of novel conopressins from Conus miliaris

2020

Journal Article

Structure-function of the high affinity substrate binding site (S1) of human norepinephrine transporter

Jha, Prerna, Ragnarsson, Lotten and Lewis, Richard J. (2020). Structure-function of the high affinity substrate binding site (S1) of human norepinephrine transporter. Frontiers in Pharmacology, 11 217, 217. doi: 10.3389/fphar.2020.00217

Structure-function of the high affinity substrate binding site (S1) of human norepinephrine transporter

2020

Journal Article

The toxicological intersection between allergen and toxin: a structural comparison of the cat dander allergenic protein Fel d1 and the slow loris brachial gland secretion protein

Scheib, Holger, Nekaris, K. Anne-Isola, Rode-Margono, Johanna, Ragnarsson, Lotten, Baumann, Kate, Dobson, James S., Wirdateti, Wirdateti, Nouwens, Amanda, Nijman, Vincent, Martelli, Paolo, Ma, Rui, Lewis, Richard J., Kwok, Hang Fai and Fry, Bryan Grieg (2020). The toxicological intersection between allergen and toxin: a structural comparison of the cat dander allergenic protein Fel d1 and the slow loris brachial gland secretion protein. Toxins, 12 (2) toxins12020086, 86. doi: 10.3390/toxins12020086

The toxicological intersection between allergen and toxin: a structural comparison of the cat dander allergenic protein Fel d1 and the slow loris brachial gland secretion protein

2020

Conference Publication

Re-evaluating the nirvana cabal deployed by piscivorous cone snails

Dutt, Mriga, Giacomotto, Jean, Ragnarsson, Lotten, Andersson, Asa, Brust, Andreas, Deakan, Zoltan, Alewood, Paul F. and Lewis, Richard J. (2020). Re-evaluating the nirvana cabal deployed by piscivorous cone snails. 20th World Congress of the International Society on Toxinology, Buenos Aires, Argentina, 8-13 September 2019. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.toxicon.2019.10.044

Re-evaluating the nirvana cabal deployed by piscivorous cone snails

Availability

Dr Lotten Ragnarsson is:
Available for supervision

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Supervision history

Completed supervision

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