Overview
Availability
- Dr Lotten Ragnarsson is:
- Available for supervision
Fields of research
Qualifications
- Masters (Research) of Science, University of Kalmar
- Licentiate of Immunology, unknown
- Doctor of Philosophy of Biochemistry and Molecular Biology, The University of Queensland
Works
Search Professor Lotten Ragnarsson’s works on UQ eSpace
2020
Conference Publication
The antiproliferative profile of a linear octopus-derived peptide in melanoma of BRAF-mutation
Fernandez-Rojo, Manuel A., Brust, Andreas, Potriquet, Jeremy, Daley, Joshua, Ragnarsson, Lotten, Andersson, Asa, Mukhopadhyay, Pamela, Wilhelm, Patrick, Chin, Yanni, Smallwood, Taylor, Clark, Richard, King, Glenn, Ramm, Grant, Waddell, Nic, Lewis, Richard, Boyle, Glen, Fry, Bryan, Alewood, Paul, Mulvenna, Jason, Miles, John and Ikonomopoulou, Maria P. (2020). The antiproliferative profile of a linear octopus-derived peptide in melanoma of BRAF-mutation. 20th World Congress of the International Society on Toxinology, Buenos Aires, Argentina, 8-13 September 2019. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.toxicon.2019.10.014
2019
Journal Article
The α1-adrenoceptor inhibitor ρ-TIA facilitates net hunting in piscivorous Conus tulipa
Dutt, Mriga, Giacomotto, Jean, Ragnarsson, Lotten, Andersson, Åsa, Brust, Andreas, Dekan, Zoltan, Alewood, Paul F. and Lewis, Richard J. (2019). The α1-adrenoceptor inhibitor ρ-TIA facilitates net hunting in piscivorous Conus tulipa. Scientific Reports, 9 (1) 17841, 17841. doi: 10.1038/s41598-019-54186-y
2019
Journal Article
Mutations in the NPxxY motif stabilize pharmacologically distinct conformational states of the α1B- and β2-adrenoceptors
Ragnarsson, Lotten, Andersson, Åsa, Thomas, Walter G. and Lewis, Richard J. (2019). Mutations in the NPxxY motif stabilize pharmacologically distinct conformational states of the α1B- and β2-adrenoceptors. Science Signaling, 12 (572) eaas9485, eaas9485. doi: 10.1126/scisignal.aas9485
2019
Journal Article
Insight into T-type calcium channel structure, function and modulation
Wang, Dan, Ragnarsson, Lotten and Lewis, Richard J. (2019). Insight into T-type calcium channel structure, function and modulation. Current medicinal chemistry, 27 (19), 3098-3122. doi: 10.2174/0929867325666181001112821
2018
Journal Article
Synthesis of Pseudellone Analogs and Characterization as Novel T-type Calcium Channel Blockers
Wang, Dan, Neupane, Pratik, Ragnarsson, Lotten, Capon, Robert J. and Lewis, Richard J. (2018). Synthesis of Pseudellone Analogs and Characterization as Novel T-type Calcium Channel Blockers. Marine Drugs, 16 (12) 475, 475. doi: 10.3390/md16120475
2018
Journal Article
Novel analgesic ω-conotoxins from the vermivorous cone snail Conus moncuri provide new insights into the evolution of conopeptides
Sousa, Silmara R., McArthur, Jeffrey R., Brust, Andreas, Bhola, Rebecca F., Rosengren, K. Johan, Ragnarsson, Lotten, Dutertre, Sebastien, Alewood, Paul F., Christie, Macdonald J., Adams, David J., Vetter, Irina and Lewis, Richard J. (2018). Novel analgesic ω-conotoxins from the vermivorous cone snail Conus moncuri provide new insights into the evolution of conopeptides. Scientific Reports, 8 (1) 13397, 13397. doi: 10.1038/s41598-018-31245-4
2017
Journal Article
Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species
Muttenthaler, Markus, Andersson, Asa, Vetter, Irina, Menon, Rohit, Busnelli, Marta, Ragnarsson, Lotten, Bergmayr, Christian, Arrowsmith, Sarah, Deuis, Jennifer R., Chiu, Han Sheng, Palpant, Nathan J., O'Brien, Margaret, Smith, Terry J., Wray, Susan, Neumann, Inga D., Gruber, Christian W., Lewis, Richard J. and Alewood, Paul F. (2017). Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species. Science Signaling, 10 (508) eaan3398, 1-13. doi: 10.1126/scisignal.aan3398
2017
Journal Article
Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingi
Sousa, Silmara R., Wingerd, Joshua S., Brust, Andreas, Bladen, Christopher, Ragnarsson, Lotten, Herzig, Volker, Deuis, Jennifer R., Dutertre, Sebastien, Vetter, Irina, Zamponi, Gerald W., King, Glenn F., Alewood, Paul F. and Lewis, Richard J. (2017). Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingi. PLoS One, 12 (9) e0182848, e0182848. doi: 10.1371/journal.pone.0182848
2017
Journal Article
Structural mechanisms for α-conotoxin activity at the human α3β4 nicotinic acetylcholine receptor
Abraham, Nikita, Healy, Michael, Ragnarsson, Lotten, Brust, Andreas, Alewood, Paul F. and Lewis, Richard J. (2017). Structural mechanisms for α-conotoxin activity at the human α3β4 nicotinic acetylcholine receptor. Scientific Reports, 7 (1) 45466, 45466. doi: 10.1038/srep45466
2017
Journal Article
Synthesis of multivalent [Lys8]-oxytocin dendrimers that inhibit visceral nociceptive responses
Wan, Jingjing, Mobli, Mehdi, Brust, Andreas, Muttenthaler, Markus, Andersson, Asa, Ragnarsson, Lotten, Castro, Joel, Vetter, Irina, Huang, Johnny X., Nilsson, Mathias, Brierley, Stuart M., Cooper, Matthew A., Lewis, Richard J. and Alewood, Paul F. (2017). Synthesis of multivalent [Lys8]-oxytocin dendrimers that inhibit visceral nociceptive responses. Australian Journal of Chemistry, 70 (2), 162-171. doi: 10.1071/CH16407
2017
Conference Publication
Defining ω-conotoxin binding site and delineating the role of the α2δ1 subunit in ω-conotoxin binding
Hassan, Mahadhi, Abraham, Nikita, Ragnarsson, Lotten K.N., Cardoso, Fernanda C. and Lewis, Richard J. (2017). Defining ω-conotoxin binding site and delineating the role of the α2δ1 subunit in ω-conotoxin binding. Venom to Drugs Conference 2017, Noosa Heads, QLD Australia, 9-14 October 2017.
2017
Conference Publication
High-throughput cell-based assays for screening Cav3.2 modulators from venoms
Wang, D., Herzig, V., Dekan, Z., Ragnarsson, Lotten K. N., Cardoso, Fernanda C. and Lewis, Richard J. (2017). High-throughput cell-based assays for screening Cav3.2 modulators from venoms. Venom to Drugs Conference 2017, Noosa Heads, QLD, Australia, 9-14 October 2017.
2016
Journal Article
Escherichia coli protein expression system for Acetylcholine Binding Proteins (AChBPs)
Abraham, Nikita, Paul, Blessy, Ragnarsson, Lotten and Lewis, Richard J. (2016). Escherichia coli protein expression system for Acetylcholine Binding Proteins (AChBPs). PLoS One, 11 (6) e0157363, e0157363. doi: 10.1371/journal.pone.0157363
2016
Journal Article
Conopeptide-derived κ-opioid agonists (conorphins): potent, selective, and metabolic stable dynorphin a mimetics with antinociceptive properties
Brust, Andreas, Croker, Daniel, Colless, Barbara, Ragnarsson, Lotten K. N., Andersson, Asa, Jain, Kapil, Garcia-Caraballo, Sonia, Castro, Joel, Brierley, Stuart M., Alewood, Paul F. and Lewis, Richard J. (2016). Conopeptide-derived κ-opioid agonists (conorphins): potent, selective, and metabolic stable dynorphin a mimetics with antinociceptive properties. Journal of Medicinal Chemistry, 59 (6), 2381-2395. doi: 10.1021/acs.jmedchem.5b00911
2016
Conference Publication
Miklos Bodanszky Award Lecture Probing the Functional Complexity of Ancient Oxytocin in Health and Disease
Muttenthaler, Markus, Andersson, Asa, Ragnarsson, Lotten, Vetter, Irina, Busnelli, Marta, Chini, Bice, Arrowsmith, Sarah, Wray, Susan, de Araujo, Aline Dantas, Dutertre, Sebastien, Mobli, Mehdi, Lewis, Richard J., Gruber, Christian W. and Alewood, Paul F. (2016). Miklos Bodanszky Award Lecture Probing the Functional Complexity of Ancient Oxytocin in Health and Disease. 34th European Peptide Symposium, Leipzig, Germany, 4‐9 September 2016. Hoboken, NJ United States: Wiley.
2015
Journal Article
Extracellular surface residues of theα1b-adrenoceptor critical for g protein -coupled receptor functions
Ragnarsson, Lotten, Andersson, Åsa, Thomas, Walter G. and Lewis, Richard J. (2015). Extracellular surface residues of theα1b-adrenoceptor critical for g protein -coupled receptor functions. Molecular Pharmacology, 87 (1), 121-129. doi: 10.1124/mol.114.094557
2015
Book Chapter
Research methods
Fry, B. G., Undheim, E. A. B., Jackson, T. N. W., Georgieva, D., Vetter, I., Calvete, J. J., Schieb, H., Cribb, B. W., Yang, D. C., Daly, N. L., Manchadi, M. L. Roy, Gutierrez, J. M., Roelants, K., Lomonte, B., Nicholson, G. M., Dziemborowicz, S., Lavergne, V., Ragnarsson, L., Rash, L. D., Mobli, M., Hodgson, W. C., Casewell, N. R., Nouwens, A., Wagstaff, S. C., Ali, S. A., Whitehead, D. L., Herzig, V., Monagle, P., Kurniawan, N. D. ... Sunagar, K. (2015). Research methods. Venomous reptiles and their toxins: evolution, pathophysiology and biodiscovery. (pp. 153-214) New York, NY, United States: Oxford University Press.
2014
Book Chapter
Role of ionotropic glutamate receptors in neurodegenerative and other disorders
Ragnarsson, Lotten, Dodd, Peter R. and Hynd, Matthew R. (2014). Role of ionotropic glutamate receptors in neurodegenerative and other disorders. Handbook of neurotoxicity. (pp. 1039-1070) New York, NY, United States: Springer Science+Business Media. doi: 10.1007/978-1-4614-5836-4_144
2013
Journal Article
Expression and pharmacology of endogenous Ca-v channels in SH-SY5Y human neuroblastoma cells
Sousa, Silmara R., Vetter, Irina, Ragnarsson, Lotten and Lewis, Richard J. (2013). Expression and pharmacology of endogenous Ca-v channels in SH-SY5Y human neuroblastoma cells. PloS One, 8 (3) e59293, e59293. doi: 10.1371/journal.pone.0059293
2013
Journal Article
Conopeptide p-tia defines a new allosteric site on the extracellular surface of the α1b-adrenoceptor
Ragnarsson, Lotten, Wang, Ching-I Anderson, Andersson, Asa, Fajarningsih, Dewi, Monks, Thea, Brust, Andreas, Rosengren, K. Johan and Lewis, Richard J. (2013). Conopeptide p-tia defines a new allosteric site on the extracellular surface of the α1b-adrenoceptor. Journal of Biological Chemistry, 288 (3), 1814-1827. doi: 10.1074/jbc.M112.430785
Supervision
Availability
- Dr Lotten Ragnarsson is:
- Available for supervision
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Supervision history
Completed supervision
-
2020
Doctor Philosophy
Discovery and Characterisation of Venom Peptide and Small Molecule Modulators for T-type Calcium Channels
Associate Advisor
Other advisors: Professor Richard Lewis
-
2018
Doctor Philosophy
Applying the conopeptide discovery pipeline to reveal the venom peptide complexity of the piscivorous cone snail, Conus tulipa
Associate Advisor
Other advisors: Professor Richard Lewis
-
2016
Doctor Philosophy
Investigating nAChR structure and function using AChBP and alpha-conotoxins.
Associate Advisor
Other advisors: Professor Richard Lewis
-
2016
Doctor Philosophy
Structure-function studies of norepinephrine and the allosteric inhibitor Chi-MrIA at the human norepinephrine transporter
Associate Advisor
Other advisors: Professor Richard Lewis
-
2014
Doctor Philosophy
Discovery and Characterisation of Novel Analgesic Neurotoxins, hCav2.2 Channel inhibitors, from Cone Snail and Spider Venoms
Associate Advisor
Other advisors: Professor Richard Lewis, Professor Irina Vetter
-
Master Philosophy
Characterisation of the Alpha1B-Adrenoceptor by Modeling, Dynamics and Virtual Screening
Associate Advisor
Other advisors: Professor Richard Lewis
Media
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