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2008 Journal Article Nasal abnormalities in cystic fibrosis mice independent of infection and inflammationHilliard, Tom N., Zhu, Jie, Farley, Ray, Escudero-Garcia, Sara, Wainwright, Brandon J., Jeffery, Peter K., Griesenbach, Uta, Bush, Andrew, Davies, Jane C. and Alton, Eric W. F. W. (2008). Nasal abnormalities in cystic fibrosis mice independent of infection and inflammation. American Journal of Respiratory Cell and Molecular Biology, 39 (1), 19-25. doi: 10.1165/rcmb.2007-0284OC |
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2007 Journal Article Novel neutrophil-derived proteins in bronchoalveolar lavage fluid indicate an exaggerated inflammatory response in pediatric cystic fibrosis patientsMcMorran, Brendan J., Patat, Severine A. Ouvry, Carlin, John B., Grimwood, Keith, Jones, Alun, Armstrong, David S., Galati, John C., Cooper, Peter J., Byrnes, Catherine A., Francis, Paul W., Robertson, Colin F., Hume, David A., Borchers, Christoph H., Wainwright, Claire E. and Wainwright, Brandon J. (2007). Novel neutrophil-derived proteins in bronchoalveolar lavage fluid indicate an exaggerated inflammatory response in pediatric cystic fibrosis patients. Clinical Chemistry, 53 (10), 1782-1791. doi: 10.1373/clinchem.2007.087650 |
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2007 Journal Article Wnt2 coordinates the commitment of mesoderm to hematopoietic, endothelial, and cardiac lineages in embryoid bodiesWang, H., Gilner, J. B., Bautch, V. L., Wang, D. Z., Wainwright, B. J., Kirby, S. L. and Patterson, C. (2007). Wnt2 coordinates the commitment of mesoderm to hematopoietic, endothelial, and cardiac lineages in embryoid bodies. Journal of Biological Chemistry, 282 (1), 782-791. doi: 10.1074/jbc.M606610200 |
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2007 Journal Article Sendai virus-mediated CFTR gene transfer to the airway epitheliumFerrari, S., Griesenbach, U., Iida, A., Farley, R., Wright, A. M., Zhu, J., Munkonge, F. M., Smith, S. N., You, J., Ban, H., Inoue, M., Chan, M., Singh, C., Verdon, B., Argent, B. E., Wainwright, B., Jeffery, P. K., Geddes, D. M., Porteous, D. J., Hyde, S. C., Gray, M. A., Hasegawa, M. and Alton, E. W. F. W. (2007). Sendai virus-mediated CFTR gene transfer to the airway epithelium. Gene Therapy, 14 (19), 1371-1379. doi: 10.1038/sj.gt.3302991 |
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2007 Journal Article Chimeric constructs endow the human CFTR Cl(-)channel with the gating behavior of murine CFTRScott-Ward, T. S., Cai, Z. W., Dawson, E. S., Doherty, A., Da Paula, A. C., Davidson, H., Porteous, D. J., Wainwright, B. J., Amaral, M. D., Sheppard, D. N. and Boyd, A. C. (2007). Chimeric constructs endow the human CFTR Cl(-)channel with the gating behavior of murine CFTR. Proceedings of The National Academy of Sciences of The United States of America, 104 (41), 16365-16370. doi: 10.1073/pnas.0701562104 |
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2006 Journal Article Flagellin of Pseudomonas aeruginosa inhibits Na+ transport in airway epitheliaKunzelmann, Karl, Scheidt, Kerstin, Scharf, Birgit, Ousingsawat, Jiraporn, Schreiber, Rainer, Wainwright, Brandon and McMorran, Brendan (2006). Flagellin of Pseudomonas aeruginosa inhibits Na+ transport in airway epithelia. Faseb Journal, 20 (3), 545-546. doi: 10.1096/fj.05-4454fje |
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2006 Journal Article Patched1 functions as a gatekeeper by promoting cell cycle progressionAdolphe, Christelle, Hetherington, Rehan, Ellis, Tammy and Wainwright, Brandon (2006). Patched1 functions as a gatekeeper by promoting cell cycle progression. Cancer Research, 66 (4), 2081-2088. doi: 10.1158/0008-5472.CAN-05-2146 |
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2005 Journal Article Pax9 and Jagged1 act downstream of Gli3 in vertabrate limb developmentMcGlinn, Edwina, Lammerts van Bueren, Kelly, Fiorenza, Salvatore, Mo, Rong, Poh, Alisa M., Forrest, Alistair, Soares, Marcelo Bento, Bonaldo, Maria de Fatima, Grimmond, Sean, Hui, Chi-chung, Wainwright, Brandon and Wicking, Carol (2005). Pax9 and Jagged1 act downstream of Gli3 in vertabrate limb development. Mechanisms of Development, 122 (11), 1218-1233. doi: 10.1016/j.mod.2005.06.012 |
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2005 Journal Article DHPLC analysis of patients with nevoid basal cell carcinoma syndrome reveals novel PTCH missense mutations in the serol-sensing domainMarsh, A., Wicking, C. A., Wainwright, B. J. and Chenevix-Trench, G. (2005). DHPLC analysis of patients with nevoid basal cell carcinoma syndrome reveals novel PTCH missense mutations in the serol-sensing domain. Human Mutation, 26 (3) 836, 283-293. doi: 10.1002/humu.9365 |
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2005 Journal Article Pathways to improving skin regenerationAdolphe, C. M. and Wainwright, B. J. (2005). Pathways to improving skin regeneration. Expert Reviews in Molecular Medicine, 7 (20), 1-14. doi: 10.1017/S1462399405009890 |
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2004 Journal Article Failure of a medulloblastoma-derived mutant of SUFU to suppress WNT signalingTaylor, Michael D., Zhang, Xiaoyun, Liu, Ling, Hui, Chi-Chung, Mainprize, Todd G., Scherer, Stephen W., Wainwright, Brandon, Hogg, David and Rutka, James T. (2004). Failure of a medulloblastoma-derived mutant of SUFU to suppress WNT signaling. Oncogene, 23 (26), 4577-4583. doi: 10.1038/sj.onc.1207605 |
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2004 Journal Article Functional analysis in Drosophila indicates that the NBCCS/PTCH1 mutation G509V results in activation of smoothened through a dominant-negative mechanismHime, G. R., Lada, H., Fietz, M. J., Gillies, S., Passmore, A., Wicking, C. A. and Wainwright, B. J. (2004). Functional analysis in Drosophila indicates that the NBCCS/PTCH1 mutation G509V results in activation of smoothened through a dominant-negative mechanism. Developmental Dynamics, 229 (4), 780-790. doi: 10.1002/dvdy.10499 |
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2004 Journal Article An in vivo comparative study of sonic, desert and Indian hedgehog reveals that hedgehog pathway activity regulates epidermal stem cell homeostasisAdolphe, C., Narang, M., Ellis, T., Wicking, C., Kaur, P. and Wainwright, B. (2004). An in vivo comparative study of sonic, desert and Indian hedgehog reveals that hedgehog pathway activity regulates epidermal stem cell homeostasis. Development, 131 (20), 5009-5019. doi: 10.1242/dev.01367 |
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2004 Journal Article Krt6a-Cre transgenic mice direct LoxP-mediated recombination to the companion cell layer of the hair follicle and following induction by retinoic acid to the interfollicular epidermisSmyth, Ian, Ellis, Tammy, Hetherington, Rehan, Riley, Emily, Narang, Monica, Mahony, Donna, Wicking, Carol, Rothnagel, Joseph A. and Wainwright, Brandon J. (2004). Krt6a-Cre transgenic mice direct LoxP-mediated recombination to the companion cell layer of the hair follicle and following induction by retinoic acid to the interfollicular epidermis. Journal of Investigative Dermatology, 122 (1), 232-234. doi: 10.1046/j.0022-202X.2003.22122.x |
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2003 Journal Article Effector ExoU from the type III secretion system is an important modulator of gene expression in lung epithelial cells in response to Pseudomonas aeruginosa infectionMcMorran, B., Town, L., Costelloe, E., Palmer, J., Engel, J., Hume, D. and Wainwright, B. (2003). Effector ExoU from the type III secretion system is an important modulator of gene expression in lung epithelial cells in response to Pseudomonas aeruginosa infection. Infection And Immunity, 71 (10), 6035-6044. doi: 10.1128/IAI.71.10.6035-6044.2003 |
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2003 Journal Article Genetic control of the innate immune responseWells, C. A., Ravasi, T., Faulkner, G. J., Carninci, P., Okazaki, Y., Hayashizaki, Y., Sweet, M.J., Wainwright, B. J. and Hume, D. A. (2003). Genetic control of the innate immune response. BMC Immunology, 4 (Article 5) 5, 1-18. doi: 10.1186/1471-2172-4-5 |
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2003 Journal Article Fraser syndrome and mouse blebbed phenotype caused by mutations in FRAS1/Fras1 encoding a putative extracellular matrix protein (Letter)McGregor, Lesley, Makela, Vile, Darling, Susan M., Vrontou, Sofia, Chalepakis, Georges, Roberts, Catherine, Smart, Nicola, Rutland, Paul, Prescott, Natalie, Hopkins, Jason, Bentley, Elizabeth, Shaw, Alison, Roberts, Emma, Mueller, Robert, Jadeja, Shalini, Philip, Nicole, Nelson, John, Francannet, Christine, Perez-Aytes, Antonio, Megarbane, Andre, Kerr, Bronwyn, Wainwright, Brandon J., Woolf, Adrian S., Winter, Robin M. and Scambler, Peter J. (2003). Fraser syndrome and mouse blebbed phenotype caused by mutations in FRAS1/Fras1 encoding a putative extracellular matrix protein (Letter). Nature Genetics, 34 (2), 203-208. doi: 10.1038/ng1142 |
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2003 Journal Article GFP-tagged CFTR transgene is functional in the G551D cystic fibrosis mouse colonOceandy, D., McMorran, B., Schreiber, R., Wainwright, B. J. and Kunzelmann, K. (2003). GFP-tagged CFTR transgene is functional in the G551D cystic fibrosis mouse colon. Journal of Membrane Biology, 192 (3), 159-167. doi: 10.1007/s00232-002-1072-y |
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2003 Journal Article Patched 1 conditional null allele in miceEllis, Tammy, Smyth, Ian, Riley, Emily, Graham, Scott, Elliot, Kate, Narang, Monica, Kay, Graham F., Wicking, Carol and Wainwright, Brandon (2003). Patched 1 conditional null allele in mice. Genesis, 36 (3), 158-161. doi: 10.1002/gene.10208 |
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2003 Journal Article A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouseSasmono, R. T., Oceandy, D., Pollard, J. W., Tong, W., Pavli, P., Wainwright, B. J., Ostrowski, M. C., Himes, S. R. and Hume, D. A. (2003). A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse. Blood, 101 (3), 1155-1163. doi: 10.1182/blood-2002-02-1569 |
