|
2017 Journal Article Activated Hedgehog-GLI Signaling Causes Congenital Ureteropelvic Junction ObstructionSheybani-Deloui, Sepideh, Chi, Lijun, Staite, Marian V., Cain, Jason E., Nieman, Brain J., Henkelman, R. Mark, Wainwright, Brandon J., Potter, S. Steven, Bagli, Darius J., Lorenzo, Armando J. and Rosenblum, Norman D. (2017). Activated Hedgehog-GLI Signaling Causes Congenital Ureteropelvic Junction Obstruction. Journal of the American Society of Nephrology : JASN, 29 (2), 532-544. doi: 10.1681/ASN.2017050482 |
|
2017 Journal Article A compartmentalized phosphoinositide signaling axis at cilia is regulated by INPP5E to maintain cilia and promote Sonic Hedgehog medulloblastomaConduit, S. E., Ramaswamy, V., Remke, M., Watkins, D. N., Wainwright, B. J., Taylor, M. D., Mitchell, C. A. and Dyson, J. M. (2017). A compartmentalized phosphoinositide signaling axis at cilia is regulated by INPP5E to maintain cilia and promote Sonic Hedgehog medulloblastoma. Oncogene, 36 (43), 5969-5984. doi: 10.1038/onc.2017.208 |
|
2017 Journal Article Inhibition of CDK4/6 by palbociclib significantly extends survival in medulloblastoma patient-derived xenograft mouse modelsSangar, Michelle L. Cook, Genovesi, Laura A., Nakamoto, Madison W., Davis, Melissa J., Knobluagh, Sue E., Ji, Pengxiang, Millar, Amanda, Wainwright, Brandon J. and Olson, James M. (2017). Inhibition of CDK4/6 by palbociclib significantly extends survival in medulloblastoma patient-derived xenograft mouse models. Clinical Cancer Research, 23 (19), 5802-5813. doi: 10.1158/1078-0432.CCR-16-2943 |
|
2017 Journal Article Patched1 patterns fibroblast growth factor 10 and forkhead box F1 expression during pulmonary branch formationHo, Uda Y. and Wainwright, Brandon J. (2017). Patched1 patterns fibroblast growth factor 10 and forkhead box F1 expression during pulmonary branch formation. Mechanisms of Development, 147, 37-48. doi: 10.1016/j.mod.2017.09.001 |
|
2017 Journal Article Downregulation of the Sonic Hedgehog/Gli pathway transcriptional target Neogenin-1 is associated with basal cell carcinoma aggressivenessCasas, Bárbara S., Adolphe, Christelle, Lois, Pablo, Navarrete, Nelson, Solís, Natalia, Bustamante, Eva, Gac, Patricio, Cabané, Patricio, Gallegos, Ivan, Wainwright, Brandon J. and Palma, Verónica (2017). Downregulation of the Sonic Hedgehog/Gli pathway transcriptional target Neogenin-1 is associated with basal cell carcinoma aggressiveness. Oncotarget, 8 (48), 84006-84018. doi: 10.18632/oncotarget.21061 |
|
2016 Journal Article The many faces of elongator in neurodevelopment and diseaseKojic, Marija and Wainwright, Brandon (2016). The many faces of elongator in neurodevelopment and disease. Frontiers in Molecular Neuroscience, 9 (NOV2016) 115, 115. doi: 10.3389/fnmol.2016.00115 |
|
2016 Journal Article MicroRNA biogenesis and hedgehog-patched signaling cooperate to regulate an important developmental transition in granule cell developmentConstantin, Lena, Constantin, Myrna and Wainwright, Brandon J. (2016). MicroRNA biogenesis and hedgehog-patched signaling cooperate to regulate an important developmental transition in granule cell development. Genetics, 202 (3), 1105-1118. doi: 10.1534/genetics.115.184176 |
|
2016 Journal Article Patched receptors sense, interpret and establish an epidermal Hedgehog signalling gradientAdolphe, Christelle, Junker, Jan Phillipp, Lyubimova, Anna, van Oudenaarden, Alexander and Wainwright, Brandon (2016). Patched receptors sense, interpret and establish an epidermal Hedgehog signalling gradient. Journal of Investigative Dermatology, 137 (1), 179-186. doi: 10.1016/j.jid.2016.06.632 |
|
2016 Journal Article Cell-type-specific expression of NFIX in the developing and adult cerebellumFraser, James, Essebier, Alexandra, Gronostajski, Richard M., Boden, Mikael, Wainwright, Brandon J., Harvey, Tracey J. and Piper, Michael (2016). Cell-type-specific expression of NFIX in the developing and adult cerebellum. Brain Structure and Function, 222 (5), 1-20. doi: 10.1007/s00429-016-1340-8 |
|
2015 Journal Article Nuclear factor one transcription factors: divergent functions in developmental versus adult stem cell populationsHarris, Lachlan, Genovesi, Laura A., Gronostajski, Richard M., Wainwright, Brandon J. and Piper, Michael (2015). Nuclear factor one transcription factors: divergent functions in developmental versus adult stem cell populations. Developmental Dynamics, 244 (3), 227-238. doi: 10.1002/dvdy.24182 |
|
2015 Journal Article MicroRNAs promote granule cell expansion in the cerebellum through Gli2Constantin, Lena and Wainwright, Brandon J. (2015). MicroRNAs promote granule cell expansion in the cerebellum through Gli2. Cerebellum, 14 (6), 688-698. doi: 10.1007/s12311-015-0672-x |
|
2014 Journal Article Zfx facilitates tumorigenesis caused by activation of the hedgehog pathwayPalmer, Colin J., Galan-Caridad, Jose M., Weisberg, Stuart P., Lei, Liang, Esquilin, Jose M., Croft, Gist F., Wainwright, Brandon, Canoll, Peter, Owens, David M. and Reizis, Boris (2014). Zfx facilitates tumorigenesis caused by activation of the hedgehog pathway. Cancer Research, 74 (20), 5914-5924. doi: 10.1158/0008-5472.CAN-14-0834 |
|
2014 Journal Article Patched 1 and Patched 2 redundancy has a key role in regulating epidermal differentiationAdolphe, Christelle, Nieuwenhuis, Erica, Villani, Rehan, Li, Zhu Juan, Kaur, Pritinder, Hui, Chi-chung and Wainwright, Brandon J. (2014). Patched 1 and Patched 2 redundancy has a key role in regulating epidermal differentiation. Journal of Investigative Dermatology, 134 (7), 1981-1990. doi: 10.1038/jid.2014.63 |
|
2014 Journal Article Neogenin1 is a Sonic Hedgehog target in medulloblastoma and is necessary for cell cycle progressionMilla, Luis A., Arros, Andrea, Espinoza, Natalie, Remke. Marc, Kool, Marcel, Taylor, Michael D., Pfister, Stefan M., Wainwright, Brandon J. and Palma, Verónica (2014). Neogenin1 is a Sonic Hedgehog target in medulloblastoma and is necessary for cell cycle progression. International Journal of Cancer, 134 (1), 21-31. doi: 10.1002/ijc.28330 |
|
2013 Journal Article Sleeping Beauty mutagenesis in a mouse medulloblastoma model defines networks that discriminate between human molecular subgroupsGenovesi, Laura A., Ng, Ching Ging, Davis, Melissa J., Remke, Marc, Taylor, Michael D., Adams, David J., Rust, Alistair G., Ward, Jerrold M., Ban, Kenneth H., Jenkins, Nancy A., Copeland, Neal G. and Wainwright, Brandon J. (2013). Sleeping Beauty mutagenesis in a mouse medulloblastoma model defines networks that discriminate between human molecular subgroups. Proceedings of the National Academy of Sciences of the United States of America, 110 (46), E4325-E4334. doi: 10.1073/pnas.1318639110 |
|
2013 Journal Article Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiationCalao, M., Sekyere, E. O., Cui, H. J., Cheung, B. B., Thomas, W. D., Keating, J., Chen, J. B., Raif, A., Jankowski, K., Davies, N. P., Bekkum, M. V., Chen, B., Tan, O., Ellis, T., Norris, M. D., Haber, M., Kim. E. S., Shohet, J. M., Trahair, T. N., Lui, T., Wainwright, B. J., Ding, H. F. and Marshall, G. M. (2013). Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation. Oncogene, 32 (31), 3616-3626. doi: 10.1038/onc.2012.368 |
|
2013 Journal Article Patched1 is required in neural crest cells for the prevention of orofacial cleftsMetzis, Vicki, Courtney, Andrew D., Kerr, Markus C., Ferguson, Charles, Rondón Galeano, Maria C., Parton, Robert G., Wainwright, Brandon J. and Wicking, Carol (2013). Patched1 is required in neural crest cells for the prevention of orofacial clefts. Human Molecular Genetics, Advance Access (24) ddt353, 1-10. doi: 10.1093/hmg/ddt353 |
|
2013 Journal Article Proliferation of Murine Midbrain Neural Stem Cells Depends upon an Endogenous Sonic Hedgehog (Shh) SourceMartinez, Constanza, Hugo Cornejo, Victor, Lois, Pablo, Ellis, Tammy, Solis, Natalia P., Wainwright, Brandon J. and Palma, Veronica (2013). Proliferation of Murine Midbrain Neural Stem Cells Depends upon an Endogenous Sonic Hedgehog (Shh) Source. PLoS One, 8 (6) e65818, e65818.1-e65818.10. doi: 10.1371/journal.pone.0065818 |
|
2013 Journal Article Murine basal cell carcinoma leads to tumor mediated alterations in endocrine lgf1 signalingVillani, Rehan M., Waters, Michael J. and Wainwright, Brandon J. (2013). Murine basal cell carcinoma leads to tumor mediated alterations in endocrine lgf1 signaling. Endocrine - Related Cancer, 20 (3), 273-281. doi: 10.1530/ERC-12-0307 |
|
2012 Journal Article Kif7 regulates Gli2 through Sufu-dependent and -independent functions during skin development and tumorigenesisLi, Zhu Juan, Nieuwenhuis, Erica, Nien, Weilun, Zhang, Xiaoyun, Zhang, Jennifer, Puviindran, Vijitha, Wainwright, Brandon J., Kim, Peter C. W. and Hui, Chi-chung (2012). Kif7 regulates Gli2 through Sufu-dependent and -independent functions during skin development and tumorigenesis. Development, 139 (22), 4152-4161. doi: 10.1242/dev.081190 |
