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2021

Journal Article

Comorbid chronic pain and depression: shared risk factors and differential antidepressant effectiveness

Roughan, William H., Campos, Adrián I., García-Marín, Luis M., Cuéllar-Partida, Gabriel, Lupton, Michelle K., Hickie, Ian B., Medland, Sarah E., Wray, Naomi R., Byrne, Enda M., Ngo, Trung Thanh, Martin, Nicholas G. and Rentería, Miguel E. (2021). Comorbid chronic pain and depression: shared risk factors and differential antidepressant effectiveness. Frontiers in Psychiatry, 12 643609, 1-13. doi: 10.3389/fpsyt.2021.643609

Comorbid chronic pain and depression: shared risk factors and differential antidepressant effectiveness

2021

Journal Article

Can network analysis of self-reported psychopathology shed light on the core phenomenology of bipolar disorders in adolescents and young adults?

Scott, Jan, Crouse, Jacob J., Ho, Nicholas, Carpenter, Joanne, Martin, Nicholas, Medland, Sarah, Parker, Richard, Byrne, Enda, Couvy-Duchesne, Baptiste, Mitchell, Brittany, Merikangas, Kathleen, Gillespie, Nathan A. and Hickie, Ian (2021). Can network analysis of self-reported psychopathology shed light on the core phenomenology of bipolar disorders in adolescents and young adults?. Bipolar Disorders, 23 (6), 584-594. doi: 10.1111/bdi.13067

Can network analysis of self-reported psychopathology shed light on the core phenomenology of bipolar disorders in adolescents and young adults?

2021

Journal Article

GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression

Wu, Yeda, Murray, Graham K., Byrne, Enda M., Sidorenko, Julia, Visscher, Peter M. and Wray, Naomi R. (2021). GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression. Nature Communications, 12 (1) 1146, 1-17. doi: 10.1038/s41467-021-21280-7

GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression

2021

Journal Article

Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

Blokland, Gabriëlla A.M., Grove, Jakob, Chen, Chia-Yen, Cotsapas, Chris, Tobet, Stuart, Handa, Robert, Ripke, Stephan, Neale, Benjamin M., Corvin, Aiden, Walters, James T.R., Farh, Kai-How, Holmans, Peter A., Lee, Phil, Bulik-Sullivan, Brendan, Collier, David A., Huang, Hailiang, Pers, Tune H., Agartz, Ingrid, Agerbo, Esben, Albus, Margot, Alexander, Madeline, Amin, Farooq, Bacanu, Silviu A., Begemann, Martin, Belliveau, Richard A., Bene, Judit, Bergen, Sarah E., Bevilacqua, Elizabeth, Bigdeli, Tim B. ... iPSYCH (2021). Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Biological Psychiatry, 91 (1), 102-117. doi: 10.1016/j.biopsych.2021.02.972

Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

2021

Journal Article

Schizophrenia polygenic risk scores in youth mental health: preliminary associations with diagnosis, clinical stage and functioning

Crouse, Jacob J., Carpenter, Joanne S., Iorfino, Frank, Lin, Tian, Ho, Nicholas, Byrne, Enda M., Henders, Anjali K., Wallace, Leanne, Hermens, Daniel F., Scott, Elizabeth M., Wray, Naomi R. and Hickie, Ian B. (2021). Schizophrenia polygenic risk scores in youth mental health: preliminary associations with diagnosis, clinical stage and functioning. BJPsych Open, 7 (2) e58, e58. doi: 10.1192/bjo.2021.14

Schizophrenia polygenic risk scores in youth mental health: preliminary associations with diagnosis, clinical stage and functioning

2021

Journal Article

A meta-analysis of the relationship between subjective sleep and depressive symptoms in adolescence

O’Callaghan, Victoria S., Couvy-Duchesne, Baptiste, Strike, Lachlan T., McMahon, Katie L., Byrne, Enda M. and Wright, Margaret J. (2021). A meta-analysis of the relationship between subjective sleep and depressive symptoms in adolescence. Sleep Medicine, 79, 134-144. doi: 10.1016/j.sleep.2021.01.011

A meta-analysis of the relationship between subjective sleep and depressive symptoms in adolescence

2020

Journal Article

Short communication: Self-reported sleep-wake disturbances preceding onset of full-threshold mood and/or psychotic syndromes in community residing adolescents and young adults

Scott, Jan, Byrne, Enda, Medland, Sarah and Hickie, Ian (2020). Short communication: Self-reported sleep-wake disturbances preceding onset of full-threshold mood and/or psychotic syndromes in community residing adolescents and young adults. Journal of Affective Disorders, 277, 592-595. doi: 10.1016/j.jad.2020.08.083

Short communication: Self-reported sleep-wake disturbances preceding onset of full-threshold mood and/or psychotic syndromes in community residing adolescents and young adults

2020

Journal Article

A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

Shen, Xueyi, Howard, David M., Adams, Mark J., Hill, W. David, Clarke, Toni-Kim, Adams, Mark J., Clarke, Toni-Kim, McIntosh, Andrew M., Deary, Ian J., Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Agerbo, Esben, Air, Tracy M., Andlauer, Till F. M., Bacanu, Silviu-Alin, Bækvad-Hansen, Marie, Beekman, Aartjan T. F., Bigdeli, Tim B., Binder, Elisabeth B., Bryois, Julien, Buttenschøn, Henriette N., Bybjerg-Grauholm, Jonas, Cai, Na, Castelao, Enrique, Christensen, Jane Hvarregaard ... McIntosh, Andrew M. (2020). A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank. Nature Communications, 11 (1) 2301. doi: 10.1038/s41467-020-16022-0

A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

2020

Journal Article

Refining attention-deficit/hyperactivity disorder and autism spectrum disorder genetic loci by integrating summary data from genome-wide association, gene expression and DNA methylation studies

Hammerschlag, Anke R., Byrne, Enda M., Bartels, Meike, Wray, Naomi R., Middeldorp, Christel M., eQTLGen Consortium, BIOS Consortium, Ahsan, Habibul, Alves, Isabel, Andiappan, Anand, Arindrarto, Wibowo, Awadalla, Philip, Battle, Alexis, Beutner, Frank, Bonder, Marc Jan, Boomsma, Dorret I., Christiansen, Mark, Claringbould, Annique, Deelen, Patrick, Esko, Tõnu, Favé, Marie-Julie, Franke, Lude, Frayling, Timothy, Gharib, Sina A., Gibson, Gregory, Heijmans, Bastiaan T., Hemani, Gibran, Jansen, Rick, Kähönen, Mika, Kalnapenkis, Anette ... Agbessi, Mawussé (2020). Refining attention-deficit/hyperactivity disorder and autism spectrum disorder genetic loci by integrating summary data from genome-wide association, gene expression and DNA methylation studies. Biological Psychiatry, 88 (6), 470-479. doi: 10.1016/j.biopsych.2020.05.002

Refining attention-deficit/hyperactivity disorder and autism spectrum disorder genetic loci by integrating summary data from genome-wide association, gene expression and DNA methylation studies

2020

Journal Article

Genetic control of temperament traits across species: association of autism spectrum disorder risk genes with cattle temperament

Costilla, Roy, Kemper, Kathryn E., Byrne, Enda M., Porto-Neto, Laercio R., Carvalheiro, Roberto, Purfield, Deirdre C., Doyle, Jennifer L., Berry, Donagh P., Moore, Stephen S., Wray, Naomi R. and Hayes, Ben J. (2020). Genetic control of temperament traits across species: association of autism spectrum disorder risk genes with cattle temperament. Genetics Selection Evolution, 52 (1) 51, 51. doi: 10.1186/s12711-020-00569-z

Genetic control of temperament traits across species: association of autism spectrum disorder risk genes with cattle temperament

2020

Journal Article

Cohort profile: the Australian genetics of depression study

Byrne, Enda M., Kirk, Katherine M., Medland, Sarah E., McGrath, John J., Colodro-Conde, Lucia, Parker, Richard, Cross, Simone, Sullivan, Lenore, Statham, Dixie J., Levinson, Douglas F., Licinio, Julio, Wray, Naomi R, Hickie, Ian B. and Martin, Nicholas G. (2020). Cohort profile: the Australian genetics of depression study. BMJ Open, 10 (5) e032580, e032580. doi: 10.1136/bmjopen-2019-032580

Cohort profile: the Australian genetics of depression study

2020

Journal Article

Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders

Byrne, Enda M., Zhu, Zhihong, Qi, Ting, Skene, Nathan G., Bryois, Julien, Pardinas, Antonio F., Stahl, Eli, Bipolar Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Rietschel, Marcella, Smoller, Jordan W., Owen, Michael J., Walters, James T. R., O’Donovan, Michael C., McGrath, John G., Hjerling-Leffler, Jens, Sullivan, Patrick F., Goddard, Michael E., Visscher, Peter M., Yang, Jian and Wray, Naomi R. (2020). Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders. Molecular Psychiatry, 26 (6), 2070-2081. doi: 10.1038/s41380-020-0705-9

Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders

2020

Journal Article

Minimal phenotyping yields genome-wide association signals of low specificity for major depression

Cai, Na, Revez, Joana A., Adams, Mark J., Andlauer, Till F. M., Breen, Gerome, Byrne, Enda M., Clarke, Toni-Kim, Forstner, Andreas J., Grabe, Hans J., Hamilton, Steven P., Levinson, Douglas F., Lewis, Cathryn M., Lewis, Glyn, Martin, Nicholas G., Milaneschi, Yuri, Mors, Ole, Müller-Myhsok, Bertram, Penninx, Brenda W. J. H., Perlis, Roy H., Pistis, Giorgio, Potash, James B., Preisig, Martin, Shi, Jianxin, Smoller, Jordan W., Streit, Fabien, Tiemeier, Henning, Uher, Rudolf, Van der Auwera, Sandra, Viktorin, Alexander ... Flint, Jonathan (2020). Minimal phenotyping yields genome-wide association signals of low specificity for major depression. Nature Genetics, 52 (4), 437-447. doi: 10.1038/s41588-020-0594-5

Minimal phenotyping yields genome-wide association signals of low specificity for major depression

2020

Journal Article

Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

Amare, Azmeraw T., Schubert, Klaus Oliver, Hou, Liping, Clark, Scott R., Papiol, Sergi, Cearns, Micah, Heilbronner, Urs, Degenhardt, Franziska, Tekola-Ayele, Fasil, Hsu, Yi-Hsiang, Shekhtman, Tatyana, Adli, Mazda, Akula, Nirmala, Akiyama, Kazufumi, Ardau, Raffaella, Arias, Bárbara, Aubry, Jean-Michel, Backlund, Lena, Bhattacharjee, Abesh Kumar, Bellivier, Frank, Benabarre, Antonio, Bengesser, Susanne, Biernacka, Joanna M., Birner, Armin, Brichant-Petitjean, Clara, Cervantes, Pablo, Chen, Hsi-Chung, Chillotti, Caterina, Cichon, Sven ... Baune, Bernhard T. (2020). Association of polygenic score for major depression with response to lithium in patients with bipolar disorder. Molecular Psychiatry, 26 (6), 2457-2470. doi: 10.1038/s41380-020-0689-5

Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

2020

Journal Article

Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank

Campos, Adrián I., García-Marín, Luis M., Byrne, Enda M., Martin, Nicholas G., Cuéllar-Partida, Gabriel and Rentería, Miguel E. (2020). Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank. Nature Communications, 11 (1) 817, 817. doi: 10.1038/s41467-020-14625-1

Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank

2020

Journal Article

Genome-wide association study of dietary intake in the UK biobank study and its associations with schizophrenia and other traits

Niarchou, Maria, Byrne, Enda M., Trzaskowski, Maciej, Sidorenko, Julia, Kemper, Kathryn E., McGrath, John J., O’ Donovan, Michael C., Owen, Michael J. and Wray, Naomi R. (2020). Genome-wide association study of dietary intake in the UK biobank study and its associations with schizophrenia and other traits. Translational Psychiatry, 10 (1) 51, 1-11. doi: 10.1038/s41398-020-0688-y

Genome-wide association study of dietary intake in the UK biobank study and its associations with schizophrenia and other traits

2020

Journal Article

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

Coleman, Jonathan R. I., Peyrot, Wouter J., Purves, Kirstin L., Davis, Katrina A. S., Rayner, Christopher, Choi, Shing Wan, Hübel, Christopher, Gaspar, Héléna A., Kan, Carol, Van der Auwera, Sandra, Adams, Mark James, Lyall, Donald M., Choi, Karmel W., Dunn, Erin C., Vassos, Evangelos, Danese, Andrea, Maughan, Barbara, Grabe, Hans J., Lewis, Cathryn M., O’Reilly, Paul F., McIntosh, Andrew M., Smith, Daniel J., Wray, Naomi R., Hotopf, Matthew, Eley, Thalia C., Breen, Gerome, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Trzaskowski, Maciej, Byrne, Enda M. ... Middeldorp, Christel M. (2020). Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank. Molecular Psychiatry, 25 (7), 1430-1446. doi: 10.1038/s41380-019-0546-6

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

2020

Journal Article

Nick Martin and the genetics of depression: sample size, sample size, sample size

Byrne, Enda M., Henders, Anjali K., Hickie, Ian B., Middeldorp, Christel M. and Wray, Naomi R. (2020). Nick Martin and the genetics of depression: sample size, sample size, sample size. Twin Research and Human Genetics, 23 (2), 1-3. doi: 10.1017/thg.2020.13

Nick Martin and the genetics of depression: sample size, sample size, sample size

2019

Journal Article

Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders

Lee, Phil H., Anttila, Verneri, Won, Hyejung, Feng, Yen-Chen A., Rosenthal, Jacob, Zhu, Zhaozhong, Tucker-Drob, Elliot M., Nivard, Michel G., Grotzinger, Andrew D., Posthuma, Danielle, Wang, Meg M.-J., Yu, Dongmei, Stahl, Eli A., Walters, Raymond K., Anney, Richard J.L., Duncan, Laramie E., Ge, Tian, Adolfsson, Rolf, Banaschewski, Tobias, Belangero, Sintia, Cook, Edwin H., Coppola, Giovanni, Derks, Eske M., Hoekstra, Pieter J., Kaprio, Jaakko, Keski-Rahkonen, Anna, Kirov, George, Kranzler, Henry R., Luykx, Jurjen J. ... Smoller, Jordan W. (2019). Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders. Cell, 179 (7), 1469-1482.e11. doi: 10.1016/j.cell.2019.11.020

Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders

2019

Journal Article

Shared and specific genetic risk factors for lifetime major depression, depressive symptoms and neuroticism in three population-based twin samples

Kendler, Kenneth S., Gardner, Charles O., Neale, Michael C., Aggen, Steve, Heath, Andrew, Colodro-Conde, Lucía, Couvyduchesne, Baptiste, Byrne, Enda M., Martin, Nicholas G. and Gillespie, Nathan A. (2019). Shared and specific genetic risk factors for lifetime major depression, depressive symptoms and neuroticism in three population-based twin samples. Psychological Medicine, 49 (16), 2745-2753. doi: 10.1017/S003329171800377X

Shared and specific genetic risk factors for lifetime major depression, depressive symptoms and neuroticism in three population-based twin samples