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2026

Journal Article

Effects of 6-months of SSRI use on DNA-methylation and gene expression in blood

Barker, Lauren F., McRae, Allan F, Yuen, Hok Pan, Henders, Anjali K, Wallace, Leanne M, Lin, Tian, Davyson, Ella, Phassouliotis, Christina, Spark, Jessica, Kerr, Melissa, Street, Rebekah, Byrne, Enda M, Amminger, G.Paul, Nelson, Barnaby, Wray, Naomi R. and McGorry, Patrick D (2026). Effects of 6-months of SSRI use on DNA-methylation and gene expression in blood. Brain, Behavior, and Immunity, 135 106520, 106520. doi: 10.1016/j.bbi.2026.106520

Effects of 6-months of SSRI use on DNA-methylation and gene expression in blood

2026

Journal Article

Genetic and Phenotypic Associations With Sustained Antidepressant Use in Major Depressive Disorder

Walker, Alicia, Mitchell, Brittany L., Lin, Tian, Crouse, Jacob J., Albinana, Clara, Yap, Chloe X., Lynall, Mary Ellen, Lind, Penelope A., Cipriani, Andrea, Byrne, Enda M., Medland, Sarah E., Martin, Nicholas G., Taquet, Maxime, Hickie, Ian B. and Wray, Naomi R. (2026). Genetic and Phenotypic Associations With Sustained Antidepressant Use in Major Depressive Disorder. Jama Psychiatry, 83 (3), 247-258. doi: 10.1001/jamapsychiatry.2025.4372

Genetic and Phenotypic Associations With Sustained Antidepressant Use in Major Depressive Disorder

2026

Journal Article

Are There Causal Associations Between Obsessive-Compulsive Disorder and Cardiometabolic Phenotypes? A Genetic Correlation and Bi-Directional Mendelian Randomization Study

Wootton, Robyn E., Crowley, James J., Pol-Fuster, Josep, Holmberg, Anna, Rück, Christian, Strom, Nora I., Gerring, Zachary F., Galimberti, Marco, Yu, Dongmei, Halvorsen, Matthew W., Abdellaoui, Abdel, Rodriguez-Fontenla, Cristina, Sealock, Julia M., Bigdeli, Tim, Coleman, Jonathan R. I., Mahjani, Behrang, Thorp, Jackson G., Bey, Katharina Burton, Christie, L., Luykx, Jurjen J., Zai, Gwyneth, Alemany, Silvia, Andre, Christine, Askland, Kathleen D., Banaj, Nerisa, Barlassina, Cristina, Nissen, Becker, Bienvenu, Judith, Joseph, O. ... Fernández de la Cruz, Lorena (2026). Are There Causal Associations Between Obsessive-Compulsive Disorder and Cardiometabolic Phenotypes? A Genetic Correlation and Bi-Directional Mendelian Randomization Study. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics ajmgb.70003. doi: 10.1002/ajmgb.70003

Are There Causal Associations Between Obsessive-Compulsive Disorder and Cardiometabolic Phenotypes? A Genetic Correlation and Bi-Directional Mendelian Randomization Study

2026

Journal Article

Atypical Depression Is Associated With a Distinct Clinical, Neurobiological, Treatment Response, and Polygenic Risk Profile

Shin, Mirim, Crouse, Jacob J., Lin, Tian, Byrne, Enda M., Mitchell, Brittany L., Lind, Penelope A., Parker, Richard, Mckenna, Sarah, Tonini, Emiliana, Carpenter, Joanne S., Merikangas, Kathleen R., Wray, Naomi R., Medland, Sarah E., Martin, Nicholas G. and Hickie, Ian B. (2026). Atypical Depression Is Associated With a Distinct Clinical, Neurobiological, Treatment Response, and Polygenic Risk Profile. Biological Psychiatry. doi: 10.1016/j.biopsych.2026.01.003

Atypical Depression Is Associated With a Distinct Clinical, Neurobiological, Treatment Response, and Polygenic Risk Profile

2025

Journal Article

The Role of Genetic Data in Dissecting Depression Heterogeneity

Mitchell, Brittany L., Monistrol-Mula, Anna, Thomas, Jodi T. and Byrne, Enda M. (2025). The Role of Genetic Data in Dissecting Depression Heterogeneity. Biological Psychiatry. doi: 10.1016/j.biopsych.2025.10.029

The Role of Genetic Data in Dissecting Depression Heterogeneity

2025

Conference Publication

Unravelling sex differences in the genetic architecture of anxiety: a genome-wide association study in the UK biobank

Hu, Jihua, Lupton, Michelle, Byrne, Enda M., Martin, Nicholas G., Whiteman, David, Olsen, Catherine, Thomas, Jodi, Medland, Sarah E., Grasby, Katrina and Mitchell, Brittany (2025). Unravelling sex differences in the genetic architecture of anxiety: a genome-wide association study in the UK biobank. World Congress of Psychiatric Genetics (WCPG), Cancun, Mexico, 19-23 October 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2025.08.288

Unravelling sex differences in the genetic architecture of anxiety: a genome-wide association study in the UK biobank

2025

Journal Article

Genetic factors predicting risk of mood disorders in adolescents

Gangaraju, Swathi Hassan, Middeldorp, Christel M. and Byrne, Enda M. (2025). Genetic factors predicting risk of mood disorders in adolescents. Current Opinion in Psychiatry, 38 (6), 452-457. doi: 10.1097/yco.0000000000001044

Genetic factors predicting risk of mood disorders in adolescents

2025

Conference Publication

Distinct Clinical, Metabolic-Inflammatory-Genetic Characteristics and Treatment Responses of Atypical Depression

Shin, Mirim, Crouse, Jacob J., Lin, Tian, Byrne, Enda M., Mitchell, Brittany L., Lind, Penelope A., Parker, Richard, McKenna, Sarah, Tonini, Emiliana, Carpenter, Joanne S., Wray, Naomi, Medland, Sarah E., Martin, Nicholas G. and Hickie, Ian B. (2025). Distinct Clinical, Metabolic-Inflammatory-Genetic Characteristics and Treatment Responses of Atypical Depression. HOBOKEN: WILEY.

Distinct Clinical, Metabolic-Inflammatory-Genetic Characteristics and Treatment Responses of Atypical Depression

2025

Journal Article

Cell-type-specific DNA methylation dynamics in the prenatal and postnatal human cortex

Franklin, Alice, Davies, Jonathan P., Clifton, Nicholas E., Blake, Georgina E.T., Bamford, Rosemary, Walker, Emma M., Chioza, Barry, Frith, Martyn, Baron-Cohen, Simon, Allison, Carrie, Warrier, Varun, Tsompanidis, Alex, Adhya, Deep, Holt, Rosie, Davis, Joanna, Gu, Genie, Zhang, Yira, Okewole, Niran, Al-Rubaie, Omar, Geschwind, Daniel H., Ghoddousi, Ramin Ali Marandi, Heazell, Alexander E.P., Mill, Jonathan, Franklin, Alice, Bamford, Rosemary, Hurles, Matthew E., Martin, Hilary C., Mousa, Mahmoud, Rowitch, David H. ... Mill, Jonathan (2025). Cell-type-specific DNA methylation dynamics in the prenatal and postnatal human cortex. Cell Genomics, 5 (12) 101010, 101010-12. doi: 10.1016/j.xgen.2025.101010

Cell-type-specific DNA methylation dynamics in the prenatal and postnatal human cortex

2025

Conference Publication

Mental Health and Sleep Correlates of Self-Reported Outdoor Daylight Exposure in Over 13,000 Adults With Depression

Crouse, Jacob, Park, Shin Ho, Mitchell, Brittany, Byrne, Enda, Medland, Sarah, Lin, Tian, Scott, Jan, de Haan, Zsofi, Tonini, Emiliana, Iorfino, Frank, Wray, Naomi, Martin, Nicholas and Hickie, Ian (2025). Mental Health and Sleep Correlates of Self-Reported Outdoor Daylight Exposure in Over 13,000 Adults With Depression. HOBOKEN: WILEY.

Mental Health and Sleep Correlates of Self-Reported Outdoor Daylight Exposure in Over 13,000 Adults With Depression

2025

Journal Article

White blood cell proportions are associated with response to psychosocial therapy in young people at ultra-high risk for psychosis

Barker, Lauren F., McRae, Allan F., Yuen, Hok Pan, Henders, Anjali K., Wallace, Leanne M., Lin, Tian, Phassouliotis, Christina, Spark, Jessica, Kerr, Melissa, Byrne, Enda M., Amminger, G. Paul, Nelson, Barnaby, Wray, Naomi R. and McGorry, Patrick D. (2025). White blood cell proportions are associated with response to psychosocial therapy in young people at ultra-high risk for psychosis. Biological Psychiatry Global Open Science, 5 (5) 100546, 1-11. doi: 10.1016/j.bpsgos.2025.100546

White blood cell proportions are associated with response to psychosocial therapy in young people at ultra-high risk for psychosis

2025

Conference Publication

Circadian Depression Subtype in Adolescents: Validation Using the Brisbane Longitudinal Twin Study

Shin, Mirim, Crouse, Jacob J., Mitchell, Brittany L., Park, Shin Ho, Tonini, Emiliana, Carpenter, Joanne S., Mcaloney, Kerrie, Byrne, Enda, Medland, Sarah, Martin, Nicholas and Hickie, Ian B. (2025). Circadian Depression Subtype in Adolescents: Validation Using the Brisbane Longitudinal Twin Study. HOBOKEN: WILEY.

Circadian Depression Subtype in Adolescents: Validation Using the Brisbane Longitudinal Twin Study

2025

Conference Publication

Clinical and Genetic Correlates of Circadian Depression in the Australian Genetics of Depression Study

Tonini, Emiliana, Crouse, Jacob J., Byrne, Enda, Mitchell, Brittany L., Shin, Mirim, Carpenter, Joanne S., Medland, Sarah, Scott, Jan, Martin, Nicholas G. and Hickie, Ian B. (2025). Clinical and Genetic Correlates of Circadian Depression in the Australian Genetics of Depression Study. HOBOKEN: WILEY.

Clinical and Genetic Correlates of Circadian Depression in the Australian Genetics of Depression Study

2025

Conference Publication

Genome-Wide Association Study (GWAS) of Circadian Depression in the UK Biobank

Tonini, Emiliana, Crouse, Jacob J., Byrne, Enda, Mitchell, Brittany L., Shin, Mirim, Carpenter, Joanne S., Hindmarch, Gabrielle, Mckenna, Sarah, Iorfino, Frank and Hickie, Ian B. (2025). Genome-Wide Association Study (GWAS) of Circadian Depression in the UK Biobank. HOBOKEN: WILEY.

Genome-Wide Association Study (GWAS) of Circadian Depression in the UK Biobank

2025

Journal Article

Sex-stratified genome-wide association meta-analysis of major depressive disorder

Thomas, Jodi T., Thorp, Jackson G., Huider, Floris, Grimes, Poppy Z., Wang, Rujia, Youssef, Pierre, Coleman, Jonathan R. I., Byrne, Enda M., Adams, Mark, BIONIC consortium, van Loo, Hanna M., Penninx, Brenda W. J. H., The GLAD Study, Medland, Sarah E., Hickie, Ian B., Olsen, Catherine M., Whiteman, David C., Whalley, Heather C., Penninx, Brenda W.J.H., van Loo, Hanna M., Derks, Eske M., Eley, Thalia C., Breen, Gerome, Boomsma, Dorret I., Wray, Naomi R., Martin, Nicholas G. and Mitchell, Brittany L. (2025). Sex-stratified genome-wide association meta-analysis of major depressive disorder. Nature Communications, 16 (1) 7960, 1-15. doi: 10.1038/s41467-025-63236-1

Sex-stratified genome-wide association meta-analysis of major depressive disorder

2025

Conference Publication

Mitochondrial DNA Variants Influence Sleep in Individuals With Major Depressive Disorder

Dos Santos, Fernanda, Camacho, Natasha, Mendes-Silva, Ana Paula, Gordon, Scott D., Mitchell, Brittany L., Byrne, Enda M., Kennedy, James, Martin, Nicholas G., Melhuish-Beaupre, Lindsay and Goncalves, Vanessa (2025). Mitochondrial DNA Variants Influence Sleep in Individuals With Major Depressive Disorder. NEW YORK: ELSEVIER SCIENCE INC.

Mitochondrial DNA Variants Influence Sleep in Individuals With Major Depressive Disorder

2025

Journal Article

Systematic review and meta-analysis: predictors of relapsing, recurrent, and chronic depression in young people

Tagliaferri, Scott D., Han, Laura K.M., Khetan, Muskan, Nguyen, Joshua, Markulev, Connie, Rice, Simon, Cotton, Susan M., Berk, Michael, Byrne, Enda M., Rickwood, Debra, Davey, Christopher G., Koval, Peter, Ratheesh, Aswin, McGorry, Patrick D., Alvarez-Jimenez, Mario and Schmaal, Lianne (2025). Systematic review and meta-analysis: predictors of relapsing, recurrent, and chronic depression in young people. Journal of the American Academy of Child & Adolescent Psychiatry, 65 (2) PMID 8704565, 206-230. doi: 10.1016/j.jaac.2025.03.019

Systematic review and meta-analysis: predictors of relapsing, recurrent, and chronic depression in young people

2025

Journal Article

Caffeine consumption, psychological distress, and insomnia in a cohort of individuals with depression

McIntosh, Harry A., Borgas, Aleah J., Aouira, Nisreen, Mitchell, Brittany L., Crouse, Jacob J., Medland, Sarah E., Hickie, Ian B., Wray, Naomi R., Martin, Nicholas G., Middeldorp, Christel M. and Byrne, Enda M. (2025). Caffeine consumption, psychological distress, and insomnia in a cohort of individuals with depression. Complex Psychiatry, 11 (1), 37-49. doi: 10.1159/000545393

Caffeine consumption, psychological distress, and insomnia in a cohort of individuals with depression

2025

Journal Article

Markers of positive affect and brain state synchrony discriminate melancholic from non-melancholic depression using naturalistic stimuli

Mosley, Philip E., van der Meer, Johan N., Hamilton, Lachlan H. W., Fripp, Jurgen, Parker, Stephen, Jeganathan, Jayson, Breakspear, Michael, Parker, Richard, Holland, Rebecca, Mitchell, Brittany L., Byrne, Enda, Hickie, Ian B., Medland, Sarah E., Martin, Nicholas G. and Cocchi, Luca (2025). Markers of positive affect and brain state synchrony discriminate melancholic from non-melancholic depression using naturalistic stimuli. Molecular Psychiatry, 30 (3) 11605, 848-860. doi: 10.1038/s41380-024-02699-y

Markers of positive affect and brain state synchrony discriminate melancholic from non-melancholic depression using naturalistic stimuli

2025

Journal Article

Improving Outcomes in Mental Health (IOMH)—an Australian longitudinal clinical study of families with children with neurodevelopmental problems: cohort profile

Galligan, Dana E, Payne, Leanne, Sullivan, Daniel P., Bhadravathi Lokeshappa, Madhura, Ziser, Laura, Nunn, Lorelle, Wallace, Leanne M., Andersen, Isabella, Howarth, Sophie, Kato, Akina, Karunanithi, Mohan, Mingin, Cassandra, O’Scanaill, Sally, Aouira, Nisreen, Paramecwari, Ayu, Sanders, Matthew R., Cobham, Vanessa E., Wray, Naomi R., Henders, Anjali K., Byrne, Enda M., Heussler, Honey and Middeldorp, Christel M. (2025). Improving Outcomes in Mental Health (IOMH)—an Australian longitudinal clinical study of families with children with neurodevelopmental problems: cohort profile. BMJ Open, 15 (3) e091676, 1-12. doi: 10.1136/bmjopen-2024-091676

Improving Outcomes in Mental Health (IOMH)—an Australian longitudinal clinical study of families with children with neurodevelopmental problems: cohort profile