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2025

Journal Article

Sex-stratified genome-wide association meta-analysis of major depressive disorder

Thomas, Jodi T., Thorp, Jackson G., Huider, Floris, Grimes, Poppy Z., Wang, Rujia, Youssef, Pierre, Coleman, Jonathan R. I., Byrne, Enda M., Adams, Mark, BIONIC consortium, van Loo, Hanna M., Penninx, Brenda W. J. H., The GLAD Study, Medland, Sarah E., Hickie, Ian B., Olsen, Catherine M., Whiteman, David C., Whalley, Heather C., Penninx, Brenda W.J.H., van Loo, Hanna M., Derks, Eske M., Eley, Thalia C., Breen, Gerome, Boomsma, Dorret I., Wray, Naomi R., Martin, Nicholas G. and Mitchell, Brittany L. (2025). Sex-stratified genome-wide association meta-analysis of major depressive disorder. Nature Communications, 16 (1) 7960, 1-15. doi: 10.1038/s41467-025-63236-1

Sex-stratified genome-wide association meta-analysis of major depressive disorder

2025

Journal Article

Genome-wide analyses identify 30 loci associated with obsessive–compulsive disorder

Strom, Nora I., Gerring, Zachary F., Galimberti, Marco, Yu, Dongmei, Halvorsen, Matthew W., Abdellaoui, Abdel, Rodriguez-Fontenla, Cristina, Sealock, Julia M., Bigdeli, Tim, Coleman, Jonathan R., Mahjani, Behrang, Thorp, Jackson G., Bey, Katharina, Burton, Christie L., Luykx, Jurjen J., Zai, Gwyneth, Alemany, Silvia, Andre, Christine, Askland, Kathleen D., Bäckman, Julia, Banaj, Nerisa, Barlassina, Cristina, Nissen, Judith Becker, Bienvenu, O. Joseph, Black, Donald, Bloch, Michael H., Børte, Sigrid, Bosch, Rosa, Breen, Michael ... Mattheisen, Manuel (2025). Genome-wide analyses identify 30 loci associated with obsessive–compulsive disorder. Nature Genetics, 57 (6) 230, 1389-1401. doi: 10.1038/s41588-025-02189-z

Genome-wide analyses identify 30 loci associated with obsessive–compulsive disorder

2025

Conference Publication

Mitochondrial DNA Variants Influence Sleep in Individuals With Major Depressive Disorder

Dos Santos, Fernanda, Camacho, Natasha, Mendes-Silva, Ana Paula, Gordon, Scott D., Mitchell, Brittany L., Byrne, Enda M., Kennedy, James, Martin, Nicholas G., Melhuish-Beaupre, Lindsay and Goncalves, Vanessa (2025). Mitochondrial DNA Variants Influence Sleep in Individuals With Major Depressive Disorder. NEW YORK: ELSEVIER SCIENCE INC.

Mitochondrial DNA Variants Influence Sleep in Individuals With Major Depressive Disorder

2025

Conference Publication

Distinct Clinical, Metabolic-Inflammatory-Genetic Characteristics and Treatment Responses of Atypical Depression<i> </i>

Shin, Mirim, Crouse, Jacob, Lin, Tian, Byrne, Enda, Mitchell, Brittany, Lind, Penelope A., Parker, Richard, Mckenna, Sarah, Tonini, Emiliana and Carpenter, Joanne (2025). Distinct Clinical, Metabolic-Inflammatory-Genetic Characteristics and Treatment Responses of Atypical Depression . HOBOKEN: WILEY.

Distinct Clinical, Metabolic-Inflammatory-Genetic Characteristics and Treatment Responses of Atypical Depression<i> </i>

2025

Conference Publication

Mental Health and Sleep Correlates of Self-Reported Outdoor Daylight Exposure in Over 13,000 Adults With Depression<i> </i>

Crouse, Jacob, Park, Shin Ho, Mitchell, Brittany, Byrne, Enda, Medland, Sarah, Lin, Tian, Scott, Jan, de Haan, Zsofi, Tonini, Emiliana and Iorfino, Frank (2025). Mental Health and Sleep Correlates of Self-Reported Outdoor Daylight Exposure in Over 13,000 Adults With Depression . HOBOKEN: WILEY.

Mental Health and Sleep Correlates of Self-Reported Outdoor Daylight Exposure in Over 13,000 Adults With Depression<i> </i>

2025

Journal Article

Systematic review and meta-analysis: predictors of relapsing, recurrent, and chronic depression in young people

Tagliaferri, Scott D., Han, Laura K.M., Khetan, Muskan, Nguyen, Joshua, Markulev, Connie, Rice, Simon, Cotton, Susan M., Berk, Michael, Byrne, Enda M., Rickwood, Debra, Davey, Christopher G., Koval, Peter, Ratheesh, Aswin, McGorry, Patrick D., Alvarez-Jimenez, Mario and Schmaal, Lianne (2025). Systematic review and meta-analysis: predictors of relapsing, recurrent, and chronic depression in young people. Journal of the American Academy of Child & Adolescent Psychiatry, 65 (2) PMID 8704565, 206-230. doi: 10.1016/j.jaac.2025.03.019

Systematic review and meta-analysis: predictors of relapsing, recurrent, and chronic depression in young people

2025

Journal Article

Caffeine consumption, psychological distress, and insomnia in a cohort of individuals with depression

McIntosh, Harry A., Borgas, Aleah J., Aouira, Nisreen, Mitchell, Brittany L., Crouse, Jacob J., Medland, Sarah E., Hickie, Ian B., Wray, Naomi R., Martin, Nicholas G., Middeldorp, Christel M. and Byrne, Enda M. (2025). Caffeine consumption, psychological distress, and insomnia in a cohort of individuals with depression. Complex Psychiatry, 11 (1), 37-49. doi: 10.1159/000545393

Caffeine consumption, psychological distress, and insomnia in a cohort of individuals with depression

2025

Journal Article

Improving Outcomes in Mental Health (IOMH)—an Australian longitudinal clinical study of families with children with neurodevelopmental problems: cohort profile

Galligan, Dana E, Payne, Leanne, Sullivan, Daniel P., Bhadravathi Lokeshappa, Madhura, Ziser, Laura, Nunn, Lorelle, Wallace, Leanne M., Andersen, Isabella, Howarth, Sophie, Kato, Akina, Karunanithi, Mohan, Mingin, Cassandra, O’Scanaill, Sally, Aouira, Nisreen, Paramecwari, Ayu, Sanders, Matthew R., Cobham, Vanessa E., Wray, Naomi R., Henders, Anjali K., Byrne, Enda M., Heussler, Honey and Middeldorp, Christel M. (2025). Improving Outcomes in Mental Health (IOMH)—an Australian longitudinal clinical study of families with children with neurodevelopmental problems: cohort profile. BMJ Open, 15 (3) e091676, 1-12. doi: 10.1136/bmjopen-2024-091676

Improving Outcomes in Mental Health (IOMH)—an Australian longitudinal clinical study of families with children with neurodevelopmental problems: cohort profile

2025

Journal Article

Markers of positive affect and brain state synchrony discriminate melancholic from non-melancholic depression using naturalistic stimuli

Mosley, Philip E., van der Meer, Johan N., Hamilton, Lachlan H. W., Fripp, Jurgen, Parker, Stephen, Jeganathan, Jayson, Breakspear, Michael, Parker, Richard, Holland, Rebecca, Mitchell, Brittany L., Byrne, Enda, Hickie, Ian B., Medland, Sarah E., Martin, Nicholas G. and Cocchi, Luca (2025). Markers of positive affect and brain state synchrony discriminate melancholic from non-melancholic depression using naturalistic stimuli. Molecular Psychiatry, 30 (3) 11605, 848-860. doi: 10.1038/s41380-024-02699-y

Markers of positive affect and brain state synchrony discriminate melancholic from non-melancholic depression using naturalistic stimuli

2025

Journal Article

Mental health and sleep correlates of self-reported outdoor daylight exposure in over 13,000 adults with depression

Crouse, Jacob J., Park, Shin Ho, Mitchell, Brittany L., Byrne, Enda M., Medland, Sarah E., Lin, Tian, Scott, Jan, de Haan, Zsofi, Tonini, Emiliana, Iorfino, Frank, Wray, Naomi R., Martin, Nicholas G. and Hickie, Ian B. (2025). Mental health and sleep correlates of self-reported outdoor daylight exposure in over 13,000 adults with depression. European Psychiatry, 68 (1) e41, 1-9. doi: 10.1192/j.eurpsy.2025.20

Mental health and sleep correlates of self-reported outdoor daylight exposure in over 13,000 adults with depression

2025

Journal Article

Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies

Adams, Mark J., Streit, Fabian, Meng, Xiangrui, Awasthi, Swapnil, Adey, Brett N., Choi, Karmel W., Chundru, V. Kartik, Coleman, Jonathan R.I., Ferwerda, Bart, Foo, Jerome C., Gerring, Zachary F., Giannakopoulou, Olga, Gupta, Priya, Hall, Alisha S.M., Harder, Arvid, Howard, David M., Hübel, Christopher, Kwong, Alex S.F., Levey, Daniel F., Mitchell, Brittany L. (Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium member), Ni, Guiyan, Ota, Vanessa K., Pain, Oliver, Pathak, Gita A., Schulte, Eva C., Shen, Xueyi, Thorp, Jackson G., Walker, Alicia, Yao, Shuyang ... McIntosh, Andrew M. (2025). Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies. Cell, 188 (3), 640-652.e9. doi: 10.1016/j.cell.2024.12.002

Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies

2024

Conference Publication

EXAMINING VARIANTS IN MITOCHONDRIAL DNA AND SLEEP MEASURES IN INDIVIDUALS WITH DEPRESSION

dos Santos, Fernanda, Camasho, Natasha, Gordon, Scott D., Mitchell, Brittany L., Byrne, Enda M., Kennedy, James, Martin, Nicholas G., Melhuish-Beaupre, Lindsay and Goncalves, Vanessa (2024). EXAMINING VARIANTS IN MITOCHONDRIAL DNA AND SLEEP MEASURES IN INDIVIDUALS WITH DEPRESSION. 63rd Annual Meeting of the American-College-of-Neuropsychopharmacology (ACNP), Phoenix Az, Dec 08-11, 2024. LONDON: SPRINGERNATURE.

EXAMINING VARIANTS IN MITOCHONDRIAL DNA AND SLEEP MEASURES IN INDIVIDUALS WITH DEPRESSION

2024

Journal Article

The effect of polygenic liability to mental disorders on COVID-19 outcomes in people with depression: the mediating role of anxiety

Monistrol-Mula, Anna, Felez-Nobrega, Mireia, Byrne, Enda M., Lind, Penelope A., Hickie, Ian B., Martin, Nicholas G., Medland, Sarah E., Colodro-Conde, Lucía and Mitchell, Brittany L. (2024). The effect of polygenic liability to mental disorders on COVID-19 outcomes in people with depression: the mediating role of anxiety. Psychological Medicine, 54 (15), 4140-4149. doi: 10.1017/s0033291724001983

The effect of polygenic liability to mental disorders on COVID-19 outcomes in people with depression: the mediating role of anxiety

2024

Journal Article

Development and temporal validation of a clinical prediction model of transition to psychosis in individuals at ultra-high risk in the UHR 1000+ cohort

Hartmann, Simon, Dwyer, Dominic, Cavve, Blake, Byrne, Enda M., Scott, Isabelle, Gao, Caroline, Wannan, Cassandra, Yuen, Hok Pan, Hartmann, Jessica, Lin, Ashleigh, Wood, Stephen J., Wigman, Johanna T.W., Middeldorp, Christel M., Thompson, Andrew, Amminger, Paul, Schlögelhofer, Monika, Riecher-Rössler, Anita, Chen, Eric Y.H., Hickie, Ian B., Phillips, Lisa J., Schäfer, Miriam R., Mossaheb, Nilufar, Smesny, Stefan, Berger, Gregor, de Haan, Lieuwe, Nordentoft, Merete, Verma, Swapna, Nieman, Dorien H., McGorry, Patrick D. ... Nelson, Barnaby (2024). Development and temporal validation of a clinical prediction model of transition to psychosis in individuals at ultra-high risk in the UHR 1000+ cohort. World Psychiatry, 23 (3), 400-410. doi: 10.1002/wps.21240

Development and temporal validation of a clinical prediction model of transition to psychosis in individuals at ultra-high risk in the UHR 1000+ cohort

2024

Conference Publication

Cohort Profile: Improving Outcomes Of Mental Health (IOMH) A Longitudinal Clinical Study Of Families With Children With Neurodevelopmental Problems

Galligan, Dana, Payne, Leanne, Sullivan, Daniel, Bhadravathi Lokeshappa, Madhura, Ziser, Laura, Nunn, Lorelle, Wallace, Leanne, Sanders, Matthew, Cobham, Vanessa, Wray, Naomi, Henders, Anjali, Byrne, Enda, Heussler, Helen and Middeldorp, Christel M. (2024). Cohort Profile: Improving Outcomes Of Mental Health (IOMH) A Longitudinal Clinical Study Of Families With Children With Neurodevelopmental Problems. World Congress of Psychiatric Genetics WCPG 2024, Singapore, 15-19 October 2024. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2024.08.469

Cohort Profile: Improving Outcomes Of Mental Health (IOMH) A Longitudinal Clinical Study Of Families With Children With Neurodevelopmental Problems

2024

Journal Article

Genome-wide meta-analysis of ascertainment and symptom structures of major depression in case-enriched and community cohorts

Adams, Mark J., Thorp, Jackson G., Jermy, Bradley S., Kwong, Alex S. F., Kõiv, Kadri, Grotzinger, Andrew D., Nivard, Michel G., Marshall, Sally, Milaneschi, Yuri, Baune, Bernhard T., Müller-Myhsok, Bertram, Penninx, Brenda W. J. H., Boomsma, Dorret I., Levinson, Douglas F., Breen, Gerome, Pistis, Giorgio, Grabe, Hans J., Tiemeier, Henning, Berger, Klaus, Rietschel, Marcella, Magnusson, Patrik K., Uher, Rudolf, Hamilton, Steven P., Lucae, Susanne, Lehto, Kelli, Li, Qingqin S., Byrne, Enda M., Hickie, Ian B., Martin, Nicholas G. ... Derks, Eske M. (2024). Genome-wide meta-analysis of ascertainment and symptom structures of major depression in case-enriched and community cohorts. Psychological Medicine, 54 (12), 3459-3468. doi: 10.1017/s0033291724001880

Genome-wide meta-analysis of ascertainment and symptom structures of major depression in case-enriched and community cohorts

2024

Journal Article

Patterns of stressful life events and polygenic scores for five mental disorders and neuroticism among adults with depression

Crouse, Jacob J., Park, Shin Ho, Byrne, Enda M., Mitchell, Brittany L., Scott, Jan, Medland, Sarah E., Lin, Tian, Wray, Naomi R., Martin, Nicholas G. and Hickie, Ian B. (2024). Patterns of stressful life events and polygenic scores for five mental disorders and neuroticism among adults with depression. Molecular Psychiatry, 29 (9), 2765-2773. doi: 10.1038/s41380-024-02492-x

Patterns of stressful life events and polygenic scores for five mental disorders and neuroticism among adults with depression

2024

Journal Article

Combining clinical with cognitive or magnetic resonance imaging data for predicting transition to psychosis in ultra high-risk patients: data from the PACE 400 cohort

Hartmann, Simon, Cearns, Micah, Pantelis, Christos, Dwyer, Dominic, Cavve, Blake, Byrne, Enda, Scott, Isabelle, Yuen, Hok Pan, Gao, Caroline, Allott, Kelly, Lin, Ashleigh, Wood, Stephen J., Wigman, Johanna T.W., Amminger, G. Paul, McGorry, Patrick D., Yung, Alison R., Nelson, Barnaby and Clark, Scott R. (2024). Combining clinical with cognitive or magnetic resonance imaging data for predicting transition to psychosis in ultra high-risk patients: data from the PACE 400 cohort. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 9 (4), 417-428. doi: 10.1016/j.bpsc.2023.11.009

Combining clinical with cognitive or magnetic resonance imaging data for predicting transition to psychosis in ultra high-risk patients: data from the PACE 400 cohort

2024

Journal Article

Comprehensive sex-stratified genetic analysis of 28 blood biomarkers and depression reveals a significant association between depression and low levels of total protein in females

Kiewa, Jacqueline, Meltzer-Brody, Samantha, Milgrom, Jeannette, Guintivano, Jerry, Hickie, Ian B., Whiteman, David C., Olsen, Catherine M., Medland, Sarah E., Martin, Nicholas G., Wray, Naomi R. and Byrne, Enda M. (2024). Comprehensive sex-stratified genetic analysis of 28 blood biomarkers and depression reveals a significant association between depression and low levels of total protein in females. Complex Psychiatry, 10 (1-4), 19-34. doi: 10.1159/000538058

Comprehensive sex-stratified genetic analysis of 28 blood biomarkers and depression reveals a significant association between depression and low levels of total protein in females

2024

Journal Article

Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference

Meng, Xiangrui, Navoly, Georgina, Giannakopoulou, Olga, Levey, Daniel F., Koller, Dora, Pathak, Gita A., Koen, Nastassja, Lin, Kuang, Adams, Mark J., Rentería, Miguel E., Feng, Yanzhe, Gaziano, J. Michael, Stein, Dan J., Zar, Heather J., Campbell, Megan L., van Heel, David A., Trivedi, Bhavi, Finer, Sarah, McQuillin, Andrew, Bass, Nick, Chundru, V. Kartik, Martin, Hilary C., Huang, Qin Qin, Valkovskaya, Maria, Chu, Chia-Yi, Kanjira, Susan, Kuo, Po-Hsiu, Chen, Hsi-Chung, Tsai, Shih-Jen ... BioBank Japan Project (2024). Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference. Nature Genetics, 56 (2), 222-233. doi: 10.1038/s41588-023-01596-4

Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference