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2020

Journal Article

Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

Amare, Azmeraw T., Schubert, Klaus Oliver, Hou, Liping, Clark, Scott R., Papiol, Sergi, Cearns, Micah, Heilbronner, Urs, Degenhardt, Franziska, Tekola-Ayele, Fasil, Hsu, Yi-Hsiang, Shekhtman, Tatyana, Adli, Mazda, Akula, Nirmala, Akiyama, Kazufumi, Ardau, Raffaella, Arias, Bárbara, Aubry, Jean-Michel, Backlund, Lena, Bhattacharjee, Abesh Kumar, Bellivier, Frank, Benabarre, Antonio, Bengesser, Susanne, Biernacka, Joanna M., Birner, Armin, Brichant-Petitjean, Clara, Cervantes, Pablo, Chen, Hsi-Chung, Chillotti, Caterina, Cichon, Sven ... Baune, Bernhard T. (2020). Association of polygenic score for major depression with response to lithium in patients with bipolar disorder. Molecular Psychiatry, 26 (6), 2457-2470. doi: 10.1038/s41380-020-0689-5

Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

2020

Journal Article

Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank

Campos, Adrián I., García-Marín, Luis M., Byrne, Enda M., Martin, Nicholas G., Cuéllar-Partida, Gabriel and Rentería, Miguel E. (2020). Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank. Nature Communications, 11 (1) 817, 817. doi: 10.1038/s41467-020-14625-1

Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank

2020

Journal Article

Genome-wide association study of dietary intake in the UK biobank study and its associations with schizophrenia and other traits

Niarchou, Maria, Byrne, Enda M., Trzaskowski, Maciej, Sidorenko, Julia, Kemper, Kathryn E., McGrath, John J., O’ Donovan, Michael C., Owen, Michael J. and Wray, Naomi R. (2020). Genome-wide association study of dietary intake in the UK biobank study and its associations with schizophrenia and other traits. Translational Psychiatry, 10 (1) 51, 1-11. doi: 10.1038/s41398-020-0688-y

Genome-wide association study of dietary intake in the UK biobank study and its associations with schizophrenia and other traits

2020

Journal Article

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

Coleman, Jonathan R. I., Peyrot, Wouter J., Purves, Kirstin L., Davis, Katrina A. S., Rayner, Christopher, Choi, Shing Wan, Hübel, Christopher, Gaspar, Héléna A., Kan, Carol, Van der Auwera, Sandra, Adams, Mark James, Lyall, Donald M., Choi, Karmel W., Dunn, Erin C., Vassos, Evangelos, Danese, Andrea, Maughan, Barbara, Grabe, Hans J., Lewis, Cathryn M., O’Reilly, Paul F., McIntosh, Andrew M., Smith, Daniel J., Wray, Naomi R., Hotopf, Matthew, Eley, Thalia C., Breen, Gerome, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Trzaskowski, Maciej, Byrne, Enda M. ... Middeldorp, Christel M. (2020). Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank. Molecular Psychiatry, 25 (7), 1430-1446. doi: 10.1038/s41380-019-0546-6

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

2020

Journal Article

Nick Martin and the genetics of depression: sample size, sample size, sample size

Byrne, Enda M., Henders, Anjali K., Hickie, Ian B., Middeldorp, Christel M. and Wray, Naomi R. (2020). Nick Martin and the genetics of depression: sample size, sample size, sample size. Twin Research and Human Genetics, 23 (2), 1-3. doi: 10.1017/thg.2020.13

Nick Martin and the genetics of depression: sample size, sample size, sample size

2019

Journal Article

Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders

Lee, Phil H., Anttila, Verneri, Won, Hyejung, Feng, Yen-Chen A., Rosenthal, Jacob, Zhu, Zhaozhong, Tucker-Drob, Elliot M., Nivard, Michel G., Grotzinger, Andrew D., Posthuma, Danielle, Wang, Meg M.-J., Yu, Dongmei, Stahl, Eli A., Walters, Raymond K., Anney, Richard J.L., Duncan, Laramie E., Ge, Tian, Adolfsson, Rolf, Banaschewski, Tobias, Belangero, Sintia, Cook, Edwin H., Coppola, Giovanni, Derks, Eske M., Hoekstra, Pieter J., Kaprio, Jaakko, Keski-Rahkonen, Anna, Kirov, George, Kranzler, Henry R., Luykx, Jurjen J. ... Smoller, Jordan W. (2019). Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders. Cell, 179 (7), 1469-1482.e11. doi: 10.1016/j.cell.2019.11.020

Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders

2019

Journal Article

Shared and specific genetic risk factors for lifetime major depression, depressive symptoms and neuroticism in three population-based twin samples

Kendler, Kenneth S., Gardner, Charles O., Neale, Michael C., Aggen, Steve, Heath, Andrew, Colodro-Conde, Lucía, Couvyduchesne, Baptiste, Byrne, Enda M., Martin, Nicholas G. and Gillespie, Nathan A. (2019). Shared and specific genetic risk factors for lifetime major depression, depressive symptoms and neuroticism in three population-based twin samples. Psychological Medicine, 49 (16), 2745-2753. doi: 10.1017/S003329171800377X

Shared and specific genetic risk factors for lifetime major depression, depressive symptoms and neuroticism in three population-based twin samples

2019

Journal Article

Genetic risk scores for major psychiatric disorders and the risk of postpartum psychiatric disorders

Bauer, Anna E., Liu, Xiaoqin, Byrne, Enda M., Sullivan, Patrick F., Wray, Naomi R., Agerbo, Esben, Nyegaard, Mette, Grove, Jakob, Musliner, Katherine L., Ingstrup, Katja G., Johannsen, Benedicte M. W., Mægbæk, Merete L., Wang, Yunpeng, Nordentoft, Merete, Mors, Ole, Børglum, Anders D., Werge, Thomas, Hougaard, David M., Mortensen, Preben Bo, Munk-Olsen, Trine and Meltzer-Brody, Samantha (2019). Genetic risk scores for major psychiatric disorders and the risk of postpartum psychiatric disorders. Translational Psychiatry, 9 (1) 288, 288. doi: 10.1038/s41398-019-0629-9

Genetic risk scores for major psychiatric disorders and the risk of postpartum psychiatric disorders

2019

Journal Article

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

Andlauer, Till F. M., Guzman-Parra, Jose, Streit, Fabian, Strohmaier, Jana, González, Maria José, Gil Flores, Susana, Cabaleiro Fabeiro, Francisco J., del Río Noriega, Francisco, Perez, Fermin Perez, Haro González, Jesus, Orozco Diaz, Guillermo, de Diego-Otero, Yolanda, Moreno-Küstner, Berta, Auburger, Georg, Degenhardt, Franziska, Heilmann-Heimbach, Stefanie, Herms, Stefan, Hoffmann, Per, Frank, Josef, Foo, Jerome C., Treutlein, Jens, Witt, Stephanie H., Cichon, Sven, Kogevinas, Manolis, Stahl, Eli A, Breen, Gerome, Forstner, Andreas J, McQuillin, Andrew, Ripke, Stephan ... Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2019). Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders. Molecular Psychiatry, 26 (4), 1286-1298. doi: 10.1038/s41380-019-0558-2

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

2019

Journal Article

The genetics of the mood disorder spectrum: Genome-wide association analyses of more than 185,000 cases and 439,000 controls

Coleman, Jonathan R.I., Gaspar, Héléna A., Bryois, Julien, Byrne, Enda M., Forstner, Andreas J., Holmans, Peter A., de Leeuw, Christiaan A., Mattheisen, Manuel, McQuillin, Andrew, Whitehead Pavlides, Jennifer M., Pers, Tune H., Ripke, Stephan, Stahl, Eli A., Steinberg, Stacy, Trubetskoy, Vassily, Trzaskowski, Maciej, Wang, Yunpeng, Abbott, Liam, Abdellaoui, Abdel, Adams, Mark J., Adolfsson, Annelie Nordin, Agerbo, Esben, Akil, Huda, Albani, Diego, Alliey-Rodriguez, Ney, Als, Thomas D., Andlauer, Till F.M., Anjorin, Adebayo, Antilla, Verneri ... Breen, Gerome (2019). The genetics of the mood disorder spectrum: Genome-wide association analyses of more than 185,000 cases and 439,000 controls. Biological Psychiatry, 88 (2), 169-184. doi: 10.1016/j.biopsych.2019.10.015

The genetics of the mood disorder spectrum: Genome-wide association analyses of more than 185,000 cases and 439,000 controls

2019

Other Outputs

Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank (n=408,317)

Campos, Adrián I., García-Marín, Luis M., Byrne, Enda M., Martin, Nicholas G., Cuéllar-Partida, Gabriel and Rentería, Miguel E. (2019). Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank (n=408,317). doi: 10.1101/808691

Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank (n=408,317)

2019

Journal Article

The relationship between insomnia and complex diseases-insights from genetic data

Byrne, Enda M. (2019). The relationship between insomnia and complex diseases-insights from genetic data. Genome Medicine, 11 (1) 57, 57. doi: 10.1186/s13073-019-0668-0

The relationship between insomnia and complex diseases-insights from genetic data

2019

Journal Article

Classical human leukocyte antigen alleles and C4 haplotypes are not significantly associated With depression

Glanville, Kylie P., Coleman, Jonathan R. I., Hanscombe, Ken B., Euesden, Jack, Choi, Shing Wan, Purves, Kirstin L., Breen, Gerome, Air, Tracy M., Andlauer, Till F. M., Baune, Bernhard T., Binder, Elisabeth B., Blackwood, Douglas H. R., Boomsma, Dorret I., Buttenschøn, Henriette N., Colodro-Conde, Lucía, Dannlowski, Udo, Direk, Nese, Dunn, Erin C., Forstner, Andreas J., de Geus, Eco J. C., Grabe, Hans J., Hamilton, Steven P., Jones, Ian, Jones, Lisa A., Knowles, James A., Kutalik, Zoltán, Levinson, Douglas F., Lewis, Glyn, Lind, Penelope A. ... Børglum, Anders D. (2019). Classical human leukocyte antigen alleles and C4 haplotypes are not significantly associated With depression. Biological Psychiatry, 87 (5), 419-430. doi: 10.1016/j.biopsych.2019.06.031

Classical human leukocyte antigen alleles and C4 haplotypes are not significantly associated With depression

2019

Journal Article

GWAS of suicide attempt in psychiatric disorders and association with major depression polygenic risk scores

Mullins, Niamh, Bigdeli, Tim B., Børglum, Anders D., Coleman, Jonathan R.I., Demontis, Ditte, Mehta, Divya, Power, Robert A., Ripke, Stephan, Stahl, Eli A., Starnawska, Anna, Anjorin, Adebayo, Corvin, Aiden, Sanders, Alan R., Forstner, Andreas J., Reif, Andreas, Koller, Anna C., Tkowska, Beata Swia, Baune, Bernhard T., Müller-Myhsok, Bertram, Penninx, Brenda W.J.H., Pato, Carlos, Zai, Clement, Rujescu, Dan, Hougaard, David M., Quested, Digby, Levinson, Douglas F., Binder, Elisabeth B., Byrne, Enda M., Agerbo, Esben ... Lewis, Cathryn M. (2019). GWAS of suicide attempt in psychiatric disorders and association with major depression polygenic risk scores. American Journal of Psychiatry, 176 (8), 651-660. doi: 10.1176/appi.ajp.2019.18080957

GWAS of suicide attempt in psychiatric disorders and association with major depression polygenic risk scores

2019

Journal Article

Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

Pardiñas, Antonio F., Holmans, Peter, Pocklington, Andrew J., Escott-Price, Valentina, Ripke, Stephan, Carrera, Noa, Legge, Sophie E., Bishop, Sophie, Cameron, Darren, Hamshere, Marian L., Han, Jun, Hubbard, Leon, Lynham, Amy, Mantripragada, Kiran, Rees, Elliott, MacCabe, James H., McCarroll, Steven A., Baune, Bernhard T., Breen, Gerome, Byrne, Enda M., Dannlowski, Udo, Eley, Thalia C., Hayward, Caroline, Martin, Nicholas G., McIntosh, Andrew M., Plomin, Robert, Porteous, David J., Wray, Naomi R., Caballero, Armando ... Walters, James T. R. (2019). Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection. Nature Genetics, 51 (7), 1193-1193. doi: 10.1038/s41588-019-0450-7

Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

2019

Other Outputs

The Australian Genetics of Depression Study: Study Description and Sample Characteristics

Byrne, Enda M, Kirk, Katherine M, Medland, Sarah E, McGrath, John J, Parker, Richard, Cross, Simone, Sullivan, Lenore, Statham, Dixie J, Levinson, Douglas F, Licinio, Julio, Wray, Naomi R, Hickie, Ian B and Martin, Nicholas G (2019). The Australian Genetics of Depression Study: Study Description and Sample Characteristics. doi: 10.1101/626762

The Australian Genetics of Depression Study: Study Description and Sample Characteristics

2019

Journal Article

Genome-wide association study identifies 30 loci associated with bipolar disorder

Stahl, Eli A., Breen, Gerome, Forstner, Andreas J., McQuillin, Andrew, Ripke, Stephan, Trubetskoy, Vassily, Mattheisen, Manuel, Wang, Yunpeng, Coleman, Jonathan R. I., Gaspar, Héléna A., de Leeuw, Christiaan A., Steinberg, Stacy, Pavlides, Jennifer M. Whitehead, Trzaskowski, Maciej, Byrne, Enda M., Pers, Tune H., Holmans, Peter A., Richards, Alexander L., Abbott, Liam, Agerbo, Esben, Akil, Huda, Albani, Diego, Alliey-Rodriguez, Ney, Als, Thomas D., Anjorin, Adebayo, Antilla, Verneri, Awasthi, Swapnil, Badner, Judith A., Bækvad-Hansen, Marie ... Sklar, Pamela (2019). Genome-wide association study identifies 30 loci associated with bipolar disorder. Nature Genetics, 51 (5), 793-803. doi: 10.1038/s41588-019-0397-8

Genome-wide association study identifies 30 loci associated with bipolar disorder

2019

Journal Article

Genome-wide association study of medication-use and associated disease in the UK Biobank

Wu, Yeda, Byrne, Enda M., Zheng, Zhili, Kemper, Kathryn E., Yengo, Loic, Mallett, Andrew J., Yang, Jian, Visscher, Peter M. and Wray, Naomi R. (2019). Genome-wide association study of medication-use and associated disease in the UK Biobank. Nature Communications, 10 (1) 1891, 1891. doi: 10.1038/s41467-019-09572-5

Genome-wide association study of medication-use and associated disease in the UK Biobank

2019

Journal Article

Assessment of bidirectional relationships between physical activity and depression among adults A 2-Sample mendelian randomization study

Choi, Karmel W., Chen, Chia-Yen, Stein, Murray B., Klimentidis, Yann C., Wang, Min-Jung, Koenen, Karestan C., Smoller, Jordan W., Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, TracyM., Andlauer, Till F. M., Bacanu, Silviu-Alin, Baekvad-Hansen, Marie, Beekman, Aartjan T. F., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas H. R., Bryois, Julien, Buttenschon, Henriette N., Bybjerg-Grauholm, Jonas, Cai, Na, Castelao, Enrique, Hvarregaard, Jane ... Sullivan, Patrick F. (2019). Assessment of bidirectional relationships between physical activity and depression among adults A 2-Sample mendelian randomization study. JAMA Psychiatry, 76 (4), 399-408. doi: 10.1001/jamapsychiatry.2018.4175

Assessment of bidirectional relationships between physical activity and depression among adults A 2-Sample mendelian randomization study

2019

Other Outputs

Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders

Byrne, Enda M, Zhu, Zhihong, Qi, Ting, Skene, Nathan G, Bryois, Julien, Pardinas, Antonio F, Stahl, Eli, Smoller, Jordan W, Rietschel, Marcella, Consortium, Bipolar Working Group of the Psychiatric Genomics, Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics, Owen, Michael J, Walters, James T.R., O’Donovan, Michael C, McGrath, John G, Hjerling-Leffler, Jens, Sullivan, Patrick F, Goddard, Michael E, Visscher, Peter M, Yang, Jian and Wray, Naomi R (2019). Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders. doi: 10.1101/592899

Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders