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2020

Journal Article

Refining attention-deficit/hyperactivity disorder and autism spectrum disorder genetic loci by integrating summary data from genome-wide association, gene expression and DNA methylation studies

Hammerschlag, Anke R., Byrne, Enda M., Bartels, Meike, Wray, Naomi R., Middeldorp, Christel M., eQTLGen Consortium, BIOS Consortium, Ahsan, Habibul, Alves, Isabel, Andiappan, Anand, Arindrarto, Wibowo, Awadalla, Philip, Battle, Alexis, Beutner, Frank, Bonder, Marc Jan, Boomsma, Dorret I., Christiansen, Mark, Claringbould, Annique, Deelen, Patrick, Esko, Tõnu, Favé, Marie-Julie, Franke, Lude, Frayling, Timothy, Gharib, Sina A., Gibson, Gregory, Heijmans, Bastiaan T., Hemani, Gibran, Jansen, Rick, Kähönen, Mika, Kalnapenkis, Anette ... Agbessi, Mawussé (2020). Refining attention-deficit/hyperactivity disorder and autism spectrum disorder genetic loci by integrating summary data from genome-wide association, gene expression and DNA methylation studies. Biological Psychiatry, 88 (6), 470-479. doi: 10.1016/j.biopsych.2020.05.002

Refining attention-deficit/hyperactivity disorder and autism spectrum disorder genetic loci by integrating summary data from genome-wide association, gene expression and DNA methylation studies

2020

Journal Article

Genetic control of temperament traits across species: association of autism spectrum disorder risk genes with cattle temperament

Costilla, Roy, Kemper, Kathryn E., Byrne, Enda M., Porto-Neto, Laercio R., Carvalheiro, Roberto, Purfield, Deirdre C., Doyle, Jennifer L., Berry, Donagh P., Moore, Stephen S., Wray, Naomi R. and Hayes, Ben J. (2020). Genetic control of temperament traits across species: association of autism spectrum disorder risk genes with cattle temperament. Genetics Selection Evolution, 52 (1) 51, 51. doi: 10.1186/s12711-020-00569-z

Genetic control of temperament traits across species: association of autism spectrum disorder risk genes with cattle temperament

2020

Journal Article

Cohort profile: the Australian genetics of depression study

Byrne, Enda M., Kirk, Katherine M., Medland, Sarah E., McGrath, John J., Colodro-Conde, Lucia, Parker, Richard, Cross, Simone, Sullivan, Lenore, Statham, Dixie J., Levinson, Douglas F., Licinio, Julio, Wray, Naomi R, Hickie, Ian B. and Martin, Nicholas G. (2020). Cohort profile: the Australian genetics of depression study. BMJ Open, 10 (5) e032580, e032580. doi: 10.1136/bmjopen-2019-032580

Cohort profile: the Australian genetics of depression study

2020

Other Outputs

Comorbid chronic pain and depression: Shared risk factors and differential antidepressant effectiveness

Roughan, William H., Campos, Adrián I., García-Marín, Luis M., Cuéllar-Partida, Gabriel, Lupton, Michelle K., Hickie, Ian B., Medland, Sarah E., Wray, Naomi R., Byrne, Enda M., Ngo, Trung Thanh, Martin, Nicholas G. and Rentería, Miguel E. (2020). Comorbid chronic pain and depression: Shared risk factors and differential antidepressant effectiveness. doi: 10.1101/2020.05.23.20110841

Comorbid chronic pain and depression: Shared risk factors and differential antidepressant effectiveness

2020

Journal Article

Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders

Byrne, Enda M., Zhu, Zhihong, Qi, Ting, Skene, Nathan G., Bryois, Julien, Pardinas, Antonio F., Stahl, Eli, Bipolar Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Rietschel, Marcella, Smoller, Jordan W., Owen, Michael J., Walters, James T. R., O’Donovan, Michael C., McGrath, John G., Hjerling-Leffler, Jens, Sullivan, Patrick F., Goddard, Michael E., Visscher, Peter M., Yang, Jian and Wray, Naomi R. (2020). Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders. Molecular Psychiatry, 26 (6), 2070-2081. doi: 10.1038/s41380-020-0705-9

Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders

2020

Other Outputs

Symptom-level genetic modelling identifies novel risk loci and unravels the shared genetic architecture of anxiety and depression

Thorp, Jackson G., Campos, Adrian I., Grotzinger, Andrew D., Gerring, Zachary, An, Jiyuan, Ong, Jue-Sheng, Wang, Wei, Team, 23andMe Research, Shringarpure, Suyash, Byrne, Enda M., MacGregor, Stuart, Martin, Nicholas G., Medland, Sarah E., Middeldorp, Christel M. and Derks, Eske M. (2020). Symptom-level genetic modelling identifies novel risk loci and unravels the shared genetic architecture of anxiety and depression. doi: 10.1101/2020.04.08.20057653

Symptom-level genetic modelling identifies novel risk loci and unravels the shared genetic architecture of anxiety and depression

2020

Journal Article

Minimal phenotyping yields genome-wide association signals of low specificity for major depression

Cai, Na, Revez, Joana A., Adams, Mark J., Andlauer, Till F. M., Breen, Gerome, Byrne, Enda M., Clarke, Toni-Kim, Forstner, Andreas J., Grabe, Hans J., Hamilton, Steven P., Levinson, Douglas F., Lewis, Cathryn M., Lewis, Glyn, Martin, Nicholas G., Milaneschi, Yuri, Mors, Ole, Müller-Myhsok, Bertram, Penninx, Brenda W. J. H., Perlis, Roy H., Pistis, Giorgio, Potash, James B., Preisig, Martin, Shi, Jianxin, Smoller, Jordan W., Streit, Fabien, Tiemeier, Henning, Uher, Rudolf, Van der Auwera, Sandra, Viktorin, Alexander ... Flint, Jonathan (2020). Minimal phenotyping yields genome-wide association signals of low specificity for major depression. Nature Genetics, 52 (4), 437-447. doi: 10.1038/s41588-020-0594-5

Minimal phenotyping yields genome-wide association signals of low specificity for major depression

2020

Journal Article

Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

Amare, Azmeraw T., Schubert, Klaus Oliver, Hou, Liping, Clark, Scott R., Papiol, Sergi, Cearns, Micah, Heilbronner, Urs, Degenhardt, Franziska, Tekola-Ayele, Fasil, Hsu, Yi-Hsiang, Shekhtman, Tatyana, Adli, Mazda, Akula, Nirmala, Akiyama, Kazufumi, Ardau, Raffaella, Arias, Bárbara, Aubry, Jean-Michel, Backlund, Lena, Bhattacharjee, Abesh Kumar, Bellivier, Frank, Benabarre, Antonio, Bengesser, Susanne, Biernacka, Joanna M., Birner, Armin, Brichant-Petitjean, Clara, Cervantes, Pablo, Chen, Hsi-Chung, Chillotti, Caterina, Cichon, Sven ... Baune, Bernhard T. (2020). Association of polygenic score for major depression with response to lithium in patients with bipolar disorder. Molecular Psychiatry, 26 (6), 2457-2470. doi: 10.1038/s41380-020-0689-5

Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

2020

Journal Article

Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank

Campos, Adrián I., García-Marín, Luis M., Byrne, Enda M., Martin, Nicholas G., Cuéllar-Partida, Gabriel and Rentería, Miguel E. (2020). Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank. Nature Communications, 11 (1) 817, 817. doi: 10.1038/s41467-020-14625-1

Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank

2020

Journal Article

Genome-wide association study of dietary intake in the UK biobank study and its associations with schizophrenia and other traits

Niarchou, Maria, Byrne, Enda M., Trzaskowski, Maciej, Sidorenko, Julia, Kemper, Kathryn E., McGrath, John J., O’ Donovan, Michael C., Owen, Michael J. and Wray, Naomi R. (2020). Genome-wide association study of dietary intake in the UK biobank study and its associations with schizophrenia and other traits. Translational Psychiatry, 10 (1) 51, 1-11. doi: 10.1038/s41398-020-0688-y

Genome-wide association study of dietary intake in the UK biobank study and its associations with schizophrenia and other traits

2020

Journal Article

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

Coleman, Jonathan R. I., Peyrot, Wouter J., Purves, Kirstin L., Davis, Katrina A. S., Rayner, Christopher, Choi, Shing Wan, Hübel, Christopher, Gaspar, Héléna A., Kan, Carol, Van der Auwera, Sandra, Adams, Mark James, Lyall, Donald M., Choi, Karmel W., Dunn, Erin C., Vassos, Evangelos, Danese, Andrea, Maughan, Barbara, Grabe, Hans J., Lewis, Cathryn M., O’Reilly, Paul F., McIntosh, Andrew M., Smith, Daniel J., Wray, Naomi R., Hotopf, Matthew, Eley, Thalia C., Breen, Gerome, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Trzaskowski, Maciej, Byrne, Enda M. ... Middeldorp, Christel M. (2020). Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank. Molecular Psychiatry, 25 (7), 1430-1446. doi: 10.1038/s41380-019-0546-6

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

2020

Journal Article

Nick Martin and the genetics of depression: sample size, sample size, sample size

Byrne, Enda M., Henders, Anjali K., Hickie, Ian B., Middeldorp, Christel M. and Wray, Naomi R. (2020). Nick Martin and the genetics of depression: sample size, sample size, sample size. Twin Research and Human Genetics, 23 (2), 1-3. doi: 10.1017/thg.2020.13

Nick Martin and the genetics of depression: sample size, sample size, sample size

2019

Journal Article

Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders

Lee, Phil H., Anttila, Verneri, Won, Hyejung, Feng, Yen-Chen A., Rosenthal, Jacob, Zhu, Zhaozhong, Tucker-Drob, Elliot M., Nivard, Michel G., Grotzinger, Andrew D., Posthuma, Danielle, Wang, Meg M.-J., Yu, Dongmei, Stahl, Eli A., Walters, Raymond K., Anney, Richard J.L., Duncan, Laramie E., Ge, Tian, Adolfsson, Rolf, Banaschewski, Tobias, Belangero, Sintia, Cook, Edwin H., Coppola, Giovanni, Derks, Eske M., Hoekstra, Pieter J., Kaprio, Jaakko, Keski-Rahkonen, Anna, Kirov, George, Kranzler, Henry R., Luykx, Jurjen J. ... Smoller, Jordan W. (2019). Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders. Cell, 179 (7), 1469-1482.e11. doi: 10.1016/j.cell.2019.11.020

Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders

2019

Journal Article

Shared and specific genetic risk factors for lifetime major depression, depressive symptoms and neuroticism in three population-based twin samples

Kendler, Kenneth S., Gardner, Charles O., Neale, Michael C., Aggen, Steve, Heath, Andrew, Colodro-Conde, Lucía, Couvyduchesne, Baptiste, Byrne, Enda M., Martin, Nicholas G. and Gillespie, Nathan A. (2019). Shared and specific genetic risk factors for lifetime major depression, depressive symptoms and neuroticism in three population-based twin samples. Psychological Medicine, 49 (16), 2745-2753. doi: 10.1017/S003329171800377X

Shared and specific genetic risk factors for lifetime major depression, depressive symptoms and neuroticism in three population-based twin samples

2019

Journal Article

Genetic risk scores for major psychiatric disorders and the risk of postpartum psychiatric disorders

Bauer, Anna E., Liu, Xiaoqin, Byrne, Enda M., Sullivan, Patrick F., Wray, Naomi R., Agerbo, Esben, Nyegaard, Mette, Grove, Jakob, Musliner, Katherine L., Ingstrup, Katja G., Johannsen, Benedicte M. W., Mægbæk, Merete L., Wang, Yunpeng, Nordentoft, Merete, Mors, Ole, Børglum, Anders D., Werge, Thomas, Hougaard, David M., Mortensen, Preben Bo, Munk-Olsen, Trine and Meltzer-Brody, Samantha (2019). Genetic risk scores for major psychiatric disorders and the risk of postpartum psychiatric disorders. Translational Psychiatry, 9 (1) 288, 288. doi: 10.1038/s41398-019-0629-9

Genetic risk scores for major psychiatric disorders and the risk of postpartum psychiatric disorders

2019

Journal Article

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

Andlauer, Till F. M., Guzman-Parra, Jose, Streit, Fabian, Strohmaier, Jana, González, Maria José, Gil Flores, Susana, Cabaleiro Fabeiro, Francisco J., del Río Noriega, Francisco, Perez, Fermin Perez, Haro González, Jesus, Orozco Diaz, Guillermo, de Diego-Otero, Yolanda, Moreno-Küstner, Berta, Auburger, Georg, Degenhardt, Franziska, Heilmann-Heimbach, Stefanie, Herms, Stefan, Hoffmann, Per, Frank, Josef, Foo, Jerome C., Treutlein, Jens, Witt, Stephanie H., Cichon, Sven, Kogevinas, Manolis, Stahl, Eli A, Breen, Gerome, Forstner, Andreas J, McQuillin, Andrew, Ripke, Stephan ... Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2019). Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders. Molecular Psychiatry, 26 (4), 1286-1298. doi: 10.1038/s41380-019-0558-2

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

2019

Journal Article

The genetics of the mood disorder spectrum: Genome-wide association analyses of more than 185,000 cases and 439,000 controls

Coleman, Jonathan R.I., Gaspar, Héléna A., Bryois, Julien, Byrne, Enda M., Forstner, Andreas J., Holmans, Peter A., de Leeuw, Christiaan A., Mattheisen, Manuel, McQuillin, Andrew, Whitehead Pavlides, Jennifer M., Pers, Tune H., Ripke, Stephan, Stahl, Eli A., Steinberg, Stacy, Trubetskoy, Vassily, Trzaskowski, Maciej, Wang, Yunpeng, Abbott, Liam, Abdellaoui, Abdel, Adams, Mark J., Adolfsson, Annelie Nordin, Agerbo, Esben, Akil, Huda, Albani, Diego, Alliey-Rodriguez, Ney, Als, Thomas D., Andlauer, Till F.M., Anjorin, Adebayo, Antilla, Verneri ... Breen, Gerome (2019). The genetics of the mood disorder spectrum: Genome-wide association analyses of more than 185,000 cases and 439,000 controls. Biological Psychiatry, 88 (2), 169-184. doi: 10.1016/j.biopsych.2019.10.015

The genetics of the mood disorder spectrum: Genome-wide association analyses of more than 185,000 cases and 439,000 controls

2019

Other Outputs

Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank (n=408,317)

Campos, Adrián I., García-Marín, Luis M., Byrne, Enda M., Martin, Nicholas G., Cuéllar-Partida, Gabriel and Rentería, Miguel E. (2019). Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank (n=408,317). doi: 10.1101/808691

Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank (n=408,317)

2019

Journal Article

The relationship between insomnia and complex diseases-insights from genetic data

Byrne, Enda M. (2019). The relationship between insomnia and complex diseases-insights from genetic data. Genome Medicine, 11 (1) 57, 57. doi: 10.1186/s13073-019-0668-0

The relationship between insomnia and complex diseases-insights from genetic data

2019

Journal Article

Classical human leukocyte antigen alleles and C4 haplotypes are not significantly associated With depression

Glanville, Kylie P., Coleman, Jonathan R. I., Hanscombe, Ken B., Euesden, Jack, Choi, Shing Wan, Purves, Kirstin L., Breen, Gerome, Air, Tracy M., Andlauer, Till F. M., Baune, Bernhard T., Binder, Elisabeth B., Blackwood, Douglas H. R., Boomsma, Dorret I., Buttenschøn, Henriette N., Colodro-Conde, Lucía, Dannlowski, Udo, Direk, Nese, Dunn, Erin C., Forstner, Andreas J., de Geus, Eco J. C., Grabe, Hans J., Hamilton, Steven P., Jones, Ian, Jones, Lisa A., Knowles, James A., Kutalik, Zoltán, Levinson, Douglas F., Lewis, Glyn, Lind, Penelope A. ... Børglum, Anders D. (2019). Classical human leukocyte antigen alleles and C4 haplotypes are not significantly associated With depression. Biological Psychiatry, 87 (5), 419-430. doi: 10.1016/j.biopsych.2019.06.031

Classical human leukocyte antigen alleles and C4 haplotypes are not significantly associated With depression