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2019

Conference Publication

A direct test of the diathesis-stress model for depression

Conde, Lucia Colodro, Couvy-Duchesne, Baptiste, Zhu, Gu, Coventry, William, Byrne, Enda, Gordon, Scott, Wright, Margaret, Montgomery, Grant, Madden, Pamela, Ripke, Stephan, Eaves, Lindon, Heath, Andrew, Wray, Naomi, Medland, Sarah E. and Martin, Nick (2019). A direct test of the diathesis-stress model for depression. 25th World Congress of Psychiatric Genetics (WCPG), Orlando, FL United States, 13-17 October 2017. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2017.08.045

A direct test of the diathesis-stress model for depression

2019

Conference Publication

Genomic structural equation models of major depression symptoms

Adams, Mark, Grotzinger, Andrew, Jermy, Bradley, Thorp, Jackson, Nivard, Michel, Byrne, Enda, Hickie, Ian, Martin, Nick, Medland, Sarah, Wray, Naomi, Tucker-Drob, Elliot, Lewis, Cathryn, Derks, Eske and McIntosh, Andrew (2019). Genomic structural equation models of major depression symptoms. 27th World Congress of Psychiatric Genetics (WCPG), Los Angeles, CA, United States, 26-31 October 2019. Amsterdam, The Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2019.08.042

Genomic structural equation models of major depression symptoms

2019

Conference Publication

Conditional genome-wide association analysis identifies genetic variants

Byrne, E. (2019). Conditional genome-wide association analysis identifies genetic variants. 21st Annual ISBD Conference: Global Advances in Bipolar Disorder and Depression, Sydney, Australia, 20-23 March 2019. Hoboken, NJ United States: Wiley-Blackwell Publishing.

Conditional genome-wide association analysis identifies genetic variants

2019

Conference Publication

Identification of genetic risk factors for postpartum depression

Guintivano, Jerry, Byrne, Enda, Watson, Hunna, Wray, Naomi, Meltzer-Brody, Samantha and Sullivan, Patrick (2019). Identification of genetic risk factors for postpartum depression. 27th World Congress of Psychiatric Genetics, Los Angeles, United States, 26-31 October 2019. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2019.07.194

Identification of genetic risk factors for postpartum depression

2019

Conference Publication

Integrative analysis of genome-wide association study results of attention-deficit/hyperactivity disorder (ADHD) and human fetal brain methylation data reveals novel genes associated with ADHD

Hammerschlag, Anke, Byrne, Enda, Bartels, Meike, Wray, Naomi and Middeldorp, Christel M. (2019). Integrative analysis of genome-wide association study results of attention-deficit/hyperactivity disorder (ADHD) and human fetal brain methylation data reveals novel genes associated with ADHD. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October 2018. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2018.08.063

Integrative analysis of genome-wide association study results of attention-deficit/hyperactivity disorder (ADHD) and human fetal brain methylation data reveals novel genes associated with ADHD

2019

Conference Publication

Genetic risk for depression and treatment response in the Australian genetics of depression study

Byrne, Enda, Medland, Sarah E., Hickie, Ian, Martin, Nicholas G. and Wray, Naomi (2019). Genetic risk for depression and treatment response in the Australian genetics of depression study. 27th World Congress of Psychiatric Genetics (WCPG), Los Angeles, CA, United States, 26-31 October 2019. Amsterdam, The Netherlands: Elsevier . doi: 10.1016/j.euroneuro.2019.07.109

Genetic risk for depression and treatment response in the Australian genetics of depression study

2018

Journal Article

Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

Arnau-Soler, Aleix, Adams, Mark J., Hayward, Caroline, Thomson, Pippa A., Porteous, David, Campbell, Archie, Smith, Blair H., Black, Corri, Padmanabhan, Sandosh, McIntosh, Andrew, Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Agerbo, Esben, Air, Tracy M., Andlauer, Till F.M., Bacanu, Silviu-Alin, Bækvad-Hansen, Marie, Beekman, Aartjan T.F., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas H.R., Bryois, Julien, Buttenschøn, Henriette N., Bybjerg-Grauholm, Jonas, Cai, Na ... Sullivan, Patrick F. (2018). Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder. PLoS ONE, 13 (12) e0209160, e0209160. doi: 10.1371/journal.pone.0209160

Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

2018

Journal Article

Fasoracetam in adolescents with ADHD and glutamatergic gene network variants disrupting mGluR neurotransmitter signaling

Elia, Josephine, Ungal, Grace, Kao, Charlly, Ambrosini, Alexander, De Jesus-Rosario, Nilsa, Larsen, Lene, Chiavacci, Rosetta, Wang, Tiancheng, Kurian, Christine, Titchen, Kanani, Sykes, Brian, Hwang, Sharon, Kumar, Bhumi, Potts, Jacqueline, Davis, Joshua, Malatack, Jeffrey, Slattery, Emma, Moorthy, Ganesh, Zuppa, Athena, Weller, Andrew, Byrne, Enda, Li, Yun R., Kraft, Walter K. and Hakonarson, Hakon (2018). Fasoracetam in adolescents with ADHD and glutamatergic gene network variants disrupting mGluR neurotransmitter signaling. Nature Communications, 9 (1) 4, 1-9. doi: 10.1038/s41467-017-02244-2

Fasoracetam in adolescents with ADHD and glutamatergic gene network variants disrupting mGluR neurotransmitter signaling

2018

Journal Article

PPD ACT: an app-based genetic study of postpartum depression

Guintivano, Jerry, Krohn, Holly, Lewis, Carol, Byrne, Enda M., Henders, Anjali K., Ploner, Alexander, Kirk, Katherine, Martin, Nicholas G., Milgrom, Jeannette, Wray, Naomi R., Sullivan, Patrick F. and Meltzer-Brody, Samantha (2018). PPD ACT: an app-based genetic study of postpartum depression. Translational Psychiatry, 8 (1) 260, 260. doi: 10.1038/s41398-018-0305-5

PPD ACT: an app-based genetic study of postpartum depression

2018

Journal Article

Is schizophrenia a risk factor for breast cancer?—evidence from genetic data

Byrne, Enda M., Ferreira, Manuel A.R., Xue, Angli, Lindström, Sara, Jiang, Xia, Yang, Jian, Easton, Douglas F., Wray, Naomi R. and Chenevix-Trench, Georgia (2018). Is schizophrenia a risk factor for breast cancer?—evidence from genetic data. Schizophrenia Bulletin, 45 (6), 1251-1256. doi: 10.1093/schbul/sby162

Is schizophrenia a risk factor for breast cancer?—evidence from genetic data

2018

Journal Article

Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

de Jong, Simone, Abdalla Diniz, Mateus Jose, Saloma, Andiara, Gadelha, Ary, Santoro, Marcos L., Ota, Vanessa K., Noto, Cristiano, Curtis, Charlesg, Newhouse, Stephen J., Patel, Hamel, Hall, Lynsey S., O'Reilly, Paul F., Belangero, Sintia, Bressan, Rodrigo A., Breen, Gerome, Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till F. M., Bacanu, Silviu-Alin, Baekvad-Hansen, Marie, Beekman, Aartjan T. F., Bigdeli, Tim B. ... Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium (2018). Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder. Communications Biology, 1 (163) 163. doi: 10.1038/s42003-018-0155-y

Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

2018

Journal Article

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till M. F., Bacanu, Silviu-Alin, Baekvad-Hansen, Marie, Beekman, Aartjan F. T., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas R. H., Bryois, Julien, Buttenschon, Henriette N., Bybjerg-Grauholm, Jonas, Cai, Na, Castelao, Enrique, Christensen, Jane Hvarregaard, Clarke, Toni-Kim, Coleman, Jonathan I. R., Colodro-Conde, Lucia, Couvy-Duchesne, Baptiste, Craddock, Nick, Crawford, Gregory E., Crowley, Cheynna A. ... Sullivan, Patrick F. (2018). Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. Nature Genetics, 50 (5), 668-+. doi: 10.1038/s41588-018-0090-3

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

2018

Conference Publication

PHENOTYPIC AND GENETIC ASSOCIATIONS BETWEEN SCHIZOPHRENIA AND RETINAL VESSEL DIAMETER

Meier, Madeline, Byrne, Enda, Martin, Nicholas, Wong, Tien and Sim, Xueling (2018). PHENOTYPIC AND GENETIC ASSOCIATIONS BETWEEN SCHIZOPHRENIA AND RETINAL VESSEL DIAMETER. 6th Biennial Conference of the Schizophrenia-International-Research-Society (SIRS), Florence Italy, Apr 04-08, 2018. OXFORD: OXFORD UNIV PRESS.

PHENOTYPIC AND GENETIC ASSOCIATIONS BETWEEN SCHIZOPHRENIA AND RETINAL VESSEL DIAMETER

2018

Journal Article

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

Pardiñas, Antonio F, Holmans, Peter, Pocklington, Andrew J, Escott-Price, Valentina, Ripke, Stephan, Carrera, Noa, Legge, Sophie E, Bishop, Sophie, Cameron, Darren, Hamshere, Marian L, Han, Jun, Hubbard, Leon, Lynham, Amy, Mantripragada, Kiran, Rees, Elliott, MacCabe, James H, McCarroll, Steven A, Baune, Bernhard T, Breen, Gerome, Byrne, Enda M., Dannlowski, Udo, Eley, Thalia C, Hayward, Caroline, Martin, Nicholas G., McIntosh, Andrew M, Plomin, Robert, Porteous, David J, Wray, Naomi R, Caballero, Armando ... CRESTAR Consortium (2018). Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection. Nature Genetics, 50 (3), 381-389. doi: 10.1038/s41588-018-0059-2

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

2018

Journal Article

Genome-wide gene-environment interaction in depression: a systematic evaluation of candidate genes: the childhood trauma working-group of PGC-MDD

Van der Auwera, Sandra, Peyrot, Wouter J., Milaneschi, Yuri, Hertel, Johannes, Baune, Bernhard, Breen, Gerome, Byrne, Enda, Dunn, Erin C, Fisher, Helen, Homuth, Georg, Levinson, Douglas, Lewis, Cathryn, Mills, Natalie, Mullins, Niamh, Nauck, Matthias, Pistis, Giorgio, Preisig, Martin, Rietschel, Marcella, Ripke, Stephan, Sullivan, Patrick, Teumer, Alexander, Völzke, Henry, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Boomsma, Dorret I., Wray, Naomi R., Penninx, Brenda and Grabe, Hans (2018). Genome-wide gene-environment interaction in depression: a systematic evaluation of candidate genes: the childhood trauma working-group of PGC-MDD. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, 177 (1), 40-49. doi: 10.1002/ajmg.b.32593

Genome-wide gene-environment interaction in depression: a systematic evaluation of candidate genes: the childhood trauma working-group of PGC-MDD

2018

Journal Article

Association of whole-genome and NETRIN1 signaling pathway–derived polygenic risk scores for major depressive disorder and white matter microstructure in the UK Biobank

Barbu, Miruna C., Zeng, Yanni, Shen, Xueyi, Cox, Simon R., Clarke, Toni-Kim, Gibson, Jude, Adams, Mark J., Johnstone, Mandy, Haley, Chris S., Lawrie, Stephen M., Deary, Ian J., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till F.M., Bacanu, Silviu-Alin, Bækvad-Hansen, Marie, Beekman, Aartjan T.F., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas H.R., Bryois, Julien ... Whalley, Heather C. (2018). Association of whole-genome and NETRIN1 signaling pathway–derived polygenic risk scores for major depressive disorder and white matter microstructure in the UK Biobank. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4 (1), 91-100. doi: 10.1016/j.bpsc.2018.07.006

Association of whole-genome and NETRIN1 signaling pathway–derived polygenic risk scores for major depressive disorder and white matter microstructure in the UK Biobank

2017

Journal Article

Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes

Rietschel, Liz, Streit, Fabian, Zhu, Gu, McAloney, Kerrie, Frank, Josef, Couvy-Duchesne, Baptiste, Witt, Stephanie H., Binz, Tina M., Bolton, Jennifer L., Hayward, Caroline, Direk, Nese, Anderson, Anna, Huffman, Jennifer, Wilson, James F., Campbell, Harry, Rudan, Igor, Wright, Alan, Hastie, Nicholas, Wild, Sarah H., Velders, Fleur P., Hofman, Albert, Uitterlinden, Andre G., Lahti, Jari, Räikkönen, Katri, Kajantie, Eero, Widen, Elisabeth, Palotie, Aarno, Eriksson, Johan G., Kaakinen, Marika ... Rietschel, Marcella (2017). Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes. Scientific Reports, 7 (1) 15351, 15351. doi: 10.1038/s41598-017-11852-3

Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes

2017

Journal Article

Investigating the relationship between iron and depression

Mills, Natalie T., Maier, Robert, Whitfield, John B., Wright, Margaret J., Colodro-Conde, Lucia, Byrne, Enda M., Scott, James G., Byrne, Gerard J., Hansell, Narelle K., Vinkhuyzen, Anna A. E., CouvyDuchesne, Baptiste, Montgomery, Grant W., Henders, Anjali K., Martin, Nicholas G., Wray, Naomi R. and Benyamin, Beben (2017). Investigating the relationship between iron and depression. Journal of Psychiatric Research, 94, 148-155. doi: 10.1016/j.jpsychires.2017.07.006

Investigating the relationship between iron and depression

2017

Journal Article

Inference in Psychiatry via 2-Sample Mendelian Randomization-From Association to Causal Pathway?

Byrne, Enda M, Yang, Jian and Wray, Naomi R (2017). Inference in Psychiatry via 2-Sample Mendelian Randomization-From Association to Causal Pathway?. JAMA psychiatry, 74 (12), 1191-1192. doi: 10.1001/jamapsychiatry.2017.3162

Inference in Psychiatry via 2-Sample Mendelian Randomization-From Association to Causal Pathway?

2017

Conference Publication

ENRICHMENT OF GENETIC VARIANTS ASSOCIATED WITH CLINICAL RESPONSE TO LITHIUM IN CIRCADIAN CLOCK SYSTEM GENE SETS

Heilbronner, Urs, Papiol, Sergi, McCarthy, Michael, Nievergelt, Caroline, Byrne, Enda and Schulze, Thomas G. (2017). ENRICHMENT OF GENETIC VARIANTS ASSOCIATED WITH CLINICAL RESPONSE TO LITHIUM IN CIRCADIAN CLOCK SYSTEM GENE SETS. 24th World Congress of Psychiatric Genetics (WCPG), Jerusalem Israel, Oct 30-Nov 04, 2016. AMSTERDAM: ELSEVIER SCIENCE BV. doi: 10.1016/j.euroneuro.2016.09.414

ENRICHMENT OF GENETIC VARIANTS ASSOCIATED WITH CLINICAL RESPONSE TO LITHIUM IN CIRCADIAN CLOCK SYSTEM GENE SETS