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2026 Journal Article Burden of health comorbidities and associated health care costs in the Australian Genetics of Depression Study using the medication-based Rx-Risk Comorbidity IndexLind, Penelope A., Hickie, Ian B., Byrne, Enda M., Martin, Nicholas G. and Medland, Sarah E. (2026). Burden of health comorbidities and associated health care costs in the Australian Genetics of Depression Study using the medication-based Rx-Risk Comorbidity Index. Journal of Affective Disorders, 414 122397, 1-9. doi: 10.1016/j.jad.2026.122397 |
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2026 Journal Article Association between polygenic liability to depression and lifetime depression in at-risk adolescentsByrne, Enda M., Gillespie, Nathan A., Najman, Jake M., Henders, Anjali K., Mitchell, Brittany L., Dwyer, Dominic, Hartmann, Simon, Cavve, Blake S., Amminger, G. Paul, Clark, Scott, Gao, Caroline, Lin, Ashleigh, Schmaal, Lianne, Thompson, Andrew, Wood, Stephen J., Wigman, J.T.W, Yung, Alison R., Medland, Sarah E., Crouse, Jacob J., Scott, Jan, Scott, James G., Williams, Gail M., Nelson, Barnaby, Martin, Nicholas G., Hickie, Ian B., Wray, Naomi R. and Middeldorp, Christel M. (2026). Association between polygenic liability to depression and lifetime depression in at-risk adolescents. Molecular Psychiatry, 1-9. doi: 10.1038/s41380-026-03917-5 |
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2026 Journal Article THE PREDICTION OF SYMPTOM SEVERITY IN CHILDREN AND PARENTS IN A CLINICAL COHORT OF FAMILIES WITH CHILDREN WITH NEURODEVELOPMENTAL PROBLEMSMiddeldorp, Christel M., Galligan, Dana, Gangaraju, Swathi, Wray, Naomi and Byrne, Enda (2026). THE PREDICTION OF SYMPTOM SEVERITY IN CHILDREN AND PARENTS IN A CLINICAL COHORT OF FAMILIES WITH CHILDREN WITH NEURODEVELOPMENTAL PROBLEMS. European Neuropsychopharmacology, 111 113018, 113018. doi: 10.1016/j.euroneuro.2026.113018 |
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2026 Journal Article T89. ANALYSIS OF PLASMA PROTEOMIC DATA IN THE AUSTRALIAN AUTISM BIOBANK REVEALS WEAK ASSOCIATIONS WITH NEURODEVELOPMENTAL TRAITSOrmond, Shannon, Yang, Yuanhao, Neupane, Sabita, Byrne, Enda, Wallace, Leanne and Gratten, Jacob (2026). T89. ANALYSIS OF PLASMA PROTEOMIC DATA IN THE AUSTRALIAN AUTISM BIOBANK REVEALS WEAK ASSOCIATIONS WITH NEURODEVELOPMENTAL TRAITS. European Neuropsychopharmacology, 111 113346, 113346. doi: 10.1016/j.euroneuro.2026.113346 |
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2026 Journal Article THE RELATIONSHIP BETWEEN GENETIC FACTORS, URINARY METABOLISM AND NEURODEVELOPMENTAL AND INTERNALISING PROBLEMS IN CHILDRENMcIntosh, Harry, Ormond, Shannon, Gratten, Jake, Byrne, Enda and Middeldorp, Christel M. (2026). THE RELATIONSHIP BETWEEN GENETIC FACTORS, URINARY METABOLISM AND NEURODEVELOPMENTAL AND INTERNALISING PROBLEMS IN CHILDREN. European Neuropsychopharmacology, 111 113019, 113019. doi: 10.1016/j.euroneuro.2026.113019 |
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2026 Journal Article CROSS-COHORT EVALUATION OF GENETIC CONTRIBUTIONS TO CHILDHOOD PSYCHOPATHOLOGY USING MACHINE LEARNINGGangaraju, Swathi Hassan, Middeldorp, Christel M. and Byrne, Enda (2026). CROSS-COHORT EVALUATION OF GENETIC CONTRIBUTIONS TO CHILDHOOD PSYCHOPATHOLOGY USING MACHINE LEARNING. European Neuropsychopharmacology, 111 113020, 113020. doi: 10.1016/j.euroneuro.2026.113020 |
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2026 Journal Article TRANSDIAGNOSTIC GENETIC RESEARCH IN CHILDREN AND ADOLESCENTSMiddeldorp, Christel M., Byrne, Enda and Polderman, Tinca (2026). TRANSDIAGNOSTIC GENETIC RESEARCH IN CHILDREN AND ADOLESCENTS. European Neuropsychopharmacology, 111 113017, 113017-111. doi: 10.1016/j.euroneuro.2026.113017 |
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2026 Journal Article Atypical depression is associated with a distinct clinical, neurobiological, treatment response, and polygenic risk profileShin, Mirim, Crouse, Jacob J., Lin, Tian, Byrne, Enda M., Mitchell, Brittany L., Lind, Penelope A., Parker, Richard, Mckenna, Sarah, Tonini, Emiliana, Carpenter, Joanne S., Merikangas, Kathleen R., Wray, Naomi R., Medland, Sarah E., Martin, Nicholas G. and Hickie, Ian B. (2026). Atypical depression is associated with a distinct clinical, neurobiological, treatment response, and polygenic risk profile. Biological Psychiatry, 100 (5), 525-535. doi: 10.1016/j.biopsych.2026.01.003 |
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2026 Journal Article Association between menstrual cycle characteristics and mental health in early adolescenceMarla, Sushma, Gangaraju, Swathi Hassan, Nguyen, Josh, Sarasjärvi, Kiira Karoliina, Ye, Rochelle Ruby, Schmaal, Lianne, Thompson, Andrew, Clark, Scott R., Lin, Ashleigh, Wigman, Johanna T.W., Wood, Stephen, Davey, Christopher G., Guloksuz, Sinan, Nelson, Barnaby, Middeldorp, Christel M. and Byrne, Enda M. (2026). Association between menstrual cycle characteristics and mental health in early adolescence. European Child and Adolescent Psychiatry. doi: 10.1007/s00787-026-03163-8 |
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2026 Journal Article Stepping Stones Triple P: A randomised controlled trial evaluating the added benefit of an enhanced parenting program in a neurodevelopmental clinical sampleGalligan, Dana E., Payne, Leanne, Paramecwari, Ayu, Howarth, Sophie, Kato, Akina, Heussler, Helen, Sanders, Matthew R., Cobham, Vanessa E., Byrne, Enda M. and Middeldorp, Christel M. (2026). Stepping Stones Triple P: A randomised controlled trial evaluating the added benefit of an enhanced parenting program in a neurodevelopmental clinical sample. European Child and Adolescent Psychiatry. doi: 10.1007/s00787-026-03139-8 |
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2026 Journal Article Genome-wide genetic overlap between fear-based disorders and generalised anxiety disorderter Kuile, Abigail R., Mitchell, Brittany L., Lee, Sang Hyuck, Morneau-Vaillancourt, Geneviève, Skelton, Megan, Coleman, Jonathan R. I., Davies, Helena L., Mundy, Jessica, Peel, Alicia J., Hübel, Christopher, Davies, Molly R., Fürtjes, Anna E., Ahmad, Zain, Lin, Yuhao, Adey, Brett N., McGregor, Thomas, Palmos, Alish, Zvrskovec, Johan, Hotopf, Matthew, Kalsi, Gursharan, Smith, Daniel J., Veale, David, Walters, James T. R., Armour, Chérie, Hirsch, Colette R., McIntosh, Andrew M., Wray, Naomi R., Medland, Sarah E., Byrne, Enda M. ... Eley, Thalia C. (2026). Genome-wide genetic overlap between fear-based disorders and generalised anxiety disorder. Molecular Psychiatry, 1-14. doi: 10.1038/s41380-026-03677-2 |
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2026 Journal Article The role of genetic data in dissecting depression heterogeneityMitchell, Brittany L., Monistrol-Mula, Anna, Thomas, Jodi T. and Byrne, Enda M. (2026). The role of genetic data in dissecting depression heterogeneity. Biological Psychiatry, 99 (12), 1100-1109. doi: 10.1016/j.biopsych.2025.10.029 |
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2026 Journal Article Genome-wide meta-analysis of quantitatively measured generalized anxiety symptoms in individuals of European ancestrySkelton, Megan, Mitchell, Brittany L., Assary, Elham, Li, Danyang, Morneau-Vaillancourt, Genevieve, Murphy, Alan E., ter Kuile, Abigail R., Wang, Rujia, Adams, Mark J., Byrne, Enda M., Corfield, Elizabeth C., Grimes, Poppy Z., Hannigan, Laurie J., Hu, Jihua, Kõiv, Kadri, Kwong, Alex S. F., Papiol, Sergi, Pettersen, Johanne H., Pistis, Giorgio, Castelao, Enrique, Strom, Nora I., van der Most, Peter J., Anxiety Disorders Working Group of the Psychiatric Genomics Consortium, Bacanu, Silviu-Alin, Cheesman, Rosa, Purves, Kirstin L., Gedik, Hüseyin, Faucon, Annika B., Singh, Kritika ... Eley, Thalia C. (2026). Genome-wide meta-analysis of quantitatively measured generalized anxiety symptoms in individuals of European ancestry. Nature Human Behaviour, 10 (8), 1-15. doi: 10.1038/s41562-026-02476-7 |
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2026 Journal Article Poor mood after oral contraceptive use is associated with increased vulnerability to peripartum depression, premenstrual dysphoric disorder, and higher genetic risk for depressionKiewa, Jacqueline, Lind, Penelope A., Hickie, Ian B., Medland, Sarah E., Mitchell, Brittany E., Middeldorp, Christel M., Martin, Nicholas G., Wray, Naomi R. and Byrne, Enda M. (2026). Poor mood after oral contraceptive use is associated with increased vulnerability to peripartum depression, premenstrual dysphoric disorder, and higher genetic risk for depression. Archives of Womens Mental Health, 29 (3) 71, 1-13. doi: 10.1007/s00737-026-01708-z |
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2026 Journal Article Genetic and phenotypic associations With sustained antidepressant use in major depressive disorderWalker, Alicia, Mitchell, Brittany L., Lin, Tian, Crouse, Jacob J., Albinana, Clara, Yap, Chloe X., Lynall, Mary Ellen, Lind, Penelope A., Cipriani, Andrea, Byrne, Enda M., Medland, Sarah E., Martin, Nicholas G., Taquet, Maxime, Hickie, Ian B. and Wray, Naomi R. (2026). Genetic and phenotypic associations With sustained antidepressant use in major depressive disorder. Jama Psychiatry, 83 (3), 247-258. doi: 10.1001/jamapsychiatry.2025.4372 |
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2026 Journal Article Effects of 6-months of SSRI use on DNA-methylation and gene expression in bloodBarker, Lauren F., McRae, Allan F, Yuen, Hok Pan, Henders, Anjali K, Wallace, Leanne M, Lin, Tian, Davyson, Ella, Phassouliotis, Christina, Spark, Jessica, Kerr, Melissa, Street, Rebekah, Byrne, Enda M, Amminger, G.Paul, Nelson, Barnaby, Wray, Naomi R. and McGorry, Patrick D (2026). Effects of 6-months of SSRI use on DNA-methylation and gene expression in blood. Brain, Behavior, and Immunity, 135 106520. doi: 10.1016/j.bbi.2026.106520 |
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2026 Journal Article Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signalingStrom, Nora I., Verhulst, Brad, Bacanu, Silviu-Alin, Cheesman, Rosa, Purves, Kirstin L., Gedik, Hüseyin, Mitchell, Brittany L., Kwong, Alex S., Faucon, Annika B., Singh, Kritika, Medland, Sarah, Colodro-Conde, Lucia, Krebs, Kristi, Hoffmann, Per, Herms, Stefan, Gehlen, Jan, Ripke, Stephan, Awasthi, Swapnil, Palviainen, Teemu, Tasanko, Elisa M., Peterson, Roseann E., Adkins, Daniel E., Shabalin, Andrey A., Adams, Mark J., Iveson, Matthew H., Campbell, Archie, Thomas, Laurent F., Winsvold, Bendik S., Drange, Ole Kristian ... Hettema, John M. (2026). Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling. Nature Genetics, 58 (2), 275-288. doi: 10.1038/s41588-025-02485-8 |
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2026 Journal Article Are there causal associations between obsessive-compulsive disorder and cardiometabolic phenotypes? a genetic correlation and bi-directional mendelian randomization studyWootton, Robyn E., Crowley, James J., Pol-Fuster, Josep, Holmberg, Anna, Rück, Christian, Strom, Nora I., Gerring, Zachary F., Galimberti, Marco, Yu, Dongmei, Halvorsen, Matthew W., Abdellaoui, Abdel, Rodriguez-Fontenla, Cristina, Sealock, Julia M., Bigdeli, Tim, Coleman, Jonathan R. I., Mahjani, Behrang, Thorp, Jackson G., Bey, Katharina Burton, Christie, L., Luykx, Jurjen J., Zai, Gwyneth, Alemany, Silvia, Andre, Christine, Askland, Kathleen D., Banaj, Nerisa, Barlassina, Cristina, Nissen, Becker, Bienvenu, Judith, Joseph, O. ... Fernández de la Cruz, Lorena (2026). Are there causal associations between obsessive-compulsive disorder and cardiometabolic phenotypes? a genetic correlation and bi-directional mendelian randomization study. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, 201 (5), 321-330. doi: 10.1002/ajmgb.70003 |
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2026 Journal Article Unravelling sex differences in the genetic architecture of anxietyHu, Jihua, Lupton, Michelle K., Byrne, Enda M., Martin, Nicholas G., Whiteman, David C., Olsen, Catherine M., Thomas, Jodi T., Medland, Sarah E., Grasby, Katrina L. and Mitchell, Brittany L. (2026). Unravelling sex differences in the genetic architecture of anxiety. Psychological Medicine, 56 e191, 1-12. doi: 10.1017/s0033291726104760 |
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2025 Journal Article Cell-type-specific DNA methylation dynamics in the prenatal and postnatal human cortexFranklin, Alice, Davies, Jonathan P., Clifton, Nicholas E., Blake, Georgina E.T., Bamford, Rosemary, Walker, Emma M., Chioza, Barry, Frith, Martyn, Baron-Cohen, Simon, Allison, Carrie, Warrier, Varun, Tsompanidis, Alex, Adhya, Deep, Holt, Rosie, Davis, Joanna, Gu, Genie, Zhang, Yira, Okewole, Niran, Al-Rubaie, Omar, Geschwind, Daniel H., Ghoddousi, Ramin Ali Marandi, Heazell, Alexander E.P., Mill, Jonathan, Franklin, Alice, Bamford, Rosemary, Hurles, Matthew E., Martin, Hilary C., Mousa, Mahmoud, Rowitch, David H. ... Mill, Jonathan (2025). Cell-type-specific DNA methylation dynamics in the prenatal and postnatal human cortex. Cell Genomics, 5 (12) 101010, 101010. doi: 10.1016/j.xgen.2025.101010 |
