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2026 Journal Article Genome-wide genetic overlap between fear-based disorders and generalised anxiety disorderter Kuile, Abigail R., Mitchell, Brittany L., Lee, Sang Hyuck, Morneau-Vaillancourt, Geneviève, Skelton, Megan, Coleman, Jonathan R. I., Davies, Helena L., Mundy, Jessica, Peel, Alicia J., Hübel, Christopher, Davies, Molly R., Fürtjes, Anna E., Ahmad, Zain, Lin, Yuhao, Adey, Brett N., McGregor, Thomas, Palmos, Alish, Zvrskovec, Johan, Hotopf, Matthew, Kalsi, Gursharan, Smith, Daniel J., Veale, David, Walters, James T. R., Armour, Chérie, Hirsch, Colette R., McIntosh, Andrew M., Wray, Naomi R., Medland, Sarah E., Byrne, Enda M. ... Eley, Thalia C. (2026). Genome-wide genetic overlap between fear-based disorders and generalised anxiety disorder. Molecular Psychiatry, 1-14. doi: 10.1038/s41380-026-03677-2 |
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2026 Journal Article The role of genetic data in dissecting depression heterogeneityMitchell, Brittany L., Monistrol-Mula, Anna, Thomas, Jodi T. and Byrne, Enda M. (2026). The role of genetic data in dissecting depression heterogeneity. Biological Psychiatry, 99 (12), 1100-1109. doi: 10.1016/j.biopsych.2025.10.029 |
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2026 Journal Article Genome-wide meta-analysis of quantitatively measured generalized anxiety symptoms in individuals of European ancestrySkelton, Megan, Mitchell, Brittany L., Assary, Elham, Li, Danyang, Morneau-Vaillancourt, Genevieve, Murphy, Alan E., ter Kuile, Abigail R., Wang, Rujia, Adams, Mark J., Byrne, Enda M., Corfield, Elizabeth C., Grimes, Poppy Z., Hannigan, Laurie J., Hu, Jihua, Kõiv, Kadri, Kwong, Alex S. F., Papiol, Sergi, Pettersen, Johanne H., Pistis, Giorgio, Castelao, Enrique, Strom, Nora I., van der Most, Peter J., Anxiety Disorders Working Group of the Psychiatric Genomics Consortium, Bacanu, Silviu-Alin, Cheesman, Rosa, Purves, Kirstin L., Gedik, Hüseyin, Faucon, Annika B., Singh, Kritika ... Eley, Thalia C. (2026). Genome-wide meta-analysis of quantitatively measured generalized anxiety symptoms in individuals of European ancestry. Nature Human Behaviour. doi: 10.1038/s41562-026-02476-7 |
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2026 Journal Article Poor mood after oral contraceptive use is associated with increased vulnerability to peripartum depression, premenstrual dysphoric disorder, and higher genetic risk for depressionKiewa, Jacqueline, Lind, Penelope A., Hickie, Ian B., Medland, Sarah E., Mitchell, Brittany E., Middeldorp, Christel M., Martin, Nicholas G., Wray, Naomi R. and Byrne, Enda M. (2026). Poor mood after oral contraceptive use is associated with increased vulnerability to peripartum depression, premenstrual dysphoric disorder, and higher genetic risk for depression. Archives of Womens Mental Health, 29 (3) 71, 1-13. doi: 10.1007/s00737-026-01708-z |
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2026 Journal Article Genetic and phenotypic associations With sustained antidepressant use in major depressive disorderWalker, Alicia, Mitchell, Brittany L., Lin, Tian, Crouse, Jacob J., Albinana, Clara, Yap, Chloe X., Lynall, Mary Ellen, Lind, Penelope A., Cipriani, Andrea, Byrne, Enda M., Medland, Sarah E., Martin, Nicholas G., Taquet, Maxime, Hickie, Ian B. and Wray, Naomi R. (2026). Genetic and phenotypic associations With sustained antidepressant use in major depressive disorder. Jama Psychiatry, 83 (3), 247-258. doi: 10.1001/jamapsychiatry.2025.4372 |
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2026 Journal Article Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signalingStrom, Nora I., Verhulst, Brad, Bacanu, Silviu-Alin, Cheesman, Rosa, Purves, Kirstin L., Gedik, Hüseyin, Mitchell, Brittany L., Kwong, Alex S., Faucon, Annika B., Singh, Kritika, Medland, Sarah, Colodro-Conde, Lucia, Krebs, Kristi, Hoffmann, Per, Herms, Stefan, Gehlen, Jan, Ripke, Stephan, Awasthi, Swapnil, Palviainen, Teemu, Tasanko, Elisa M., Peterson, Roseann E., Adkins, Daniel E., Shabalin, Andrey A., Adams, Mark J., Iveson, Matthew H., Campbell, Archie, Thomas, Laurent F., Winsvold, Bendik S., Drange, Ole Kristian ... Hettema, John M. (2026). Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling. Nature Genetics, 58 (2), 1-14. doi: 10.1038/s41588-025-02485-8 |
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2026 Journal Article Effects of 6-months of SSRI use on DNA-methylation and gene expression in bloodBarker, Lauren F., McRae, Allan F, Yuen, Hok Pan, Henders, Anjali K, Wallace, Leanne M, Lin, Tian, Davyson, Ella, Phassouliotis, Christina, Spark, Jessica, Kerr, Melissa, Street, Rebekah, Byrne, Enda M, Amminger, G.Paul, Nelson, Barnaby, Wray, Naomi R. and McGorry, Patrick D (2026). Effects of 6-months of SSRI use on DNA-methylation and gene expression in blood. Brain, Behavior, and Immunity, 135 106520, 106520. doi: 10.1016/j.bbi.2026.106520 |
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2026 Journal Article Atypical depression is associated with a distinct clinical, neurobiological, treatment response, and polygenic risk profileShin, Mirim, Crouse, Jacob J., Lin, Tian, Byrne, Enda M., Mitchell, Brittany L., Lind, Penelope A., Parker, Richard, Mckenna, Sarah, Tonini, Emiliana, Carpenter, Joanne S., Merikangas, Kathleen R., Wray, Naomi R., Medland, Sarah E., Martin, Nicholas G. and Hickie, Ian B. (2026). Atypical depression is associated with a distinct clinical, neurobiological, treatment response, and polygenic risk profile. Biological Psychiatry. doi: 10.1016/j.biopsych.2026.01.003 |
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2026 Journal Article Are there causal associations between obsessive-compulsive disorder and cardiometabolic phenotypes? a genetic correlation and bi-directional mendelian randomization studyWootton, Robyn E., Crowley, James J., Pol-Fuster, Josep, Holmberg, Anna, Rück, Christian, Strom, Nora I., Gerring, Zachary F., Galimberti, Marco, Yu, Dongmei, Halvorsen, Matthew W., Abdellaoui, Abdel, Rodriguez-Fontenla, Cristina, Sealock, Julia M., Bigdeli, Tim, Coleman, Jonathan R. I., Mahjani, Behrang, Thorp, Jackson G., Bey, Katharina Burton, Christie, L., Luykx, Jurjen J., Zai, Gwyneth, Alemany, Silvia, Andre, Christine, Askland, Kathleen D., Banaj, Nerisa, Barlassina, Cristina, Nissen, Becker, Bienvenu, Judith, Joseph, O. ... Fernández de la Cruz, Lorena (2026). Are there causal associations between obsessive-compulsive disorder and cardiometabolic phenotypes? a genetic correlation and bi-directional mendelian randomization study. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, 201 (5), 321-330. doi: 10.1002/ajmgb.70003 |
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2026 Journal Article Unravelling sex differences in the genetic architecture of anxietyHu, Jihua, Lupton, Michelle K., Byrne, Enda M., Martin, Nicholas G., Whiteman, David C., Olsen, Catherine M., Thomas, Jodi T., Medland, Sarah E., Grasby, Katrina L. and Mitchell, Brittany L. (2026). Unravelling sex differences in the genetic architecture of anxiety. Psychological Medicine, 56 e191, e191-56. doi: 10.1017/s0033291726104760 |
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2025 Journal Article Cell-type-specific DNA methylation dynamics in the prenatal and postnatal human cortexFranklin, Alice, Davies, Jonathan P., Clifton, Nicholas E., Blake, Georgina E.T., Bamford, Rosemary, Walker, Emma M., Chioza, Barry, Frith, Martyn, Baron-Cohen, Simon, Allison, Carrie, Warrier, Varun, Tsompanidis, Alex, Adhya, Deep, Holt, Rosie, Davis, Joanna, Gu, Genie, Zhang, Yira, Okewole, Niran, Al-Rubaie, Omar, Geschwind, Daniel H., Ghoddousi, Ramin Ali Marandi, Heazell, Alexander E.P., Mill, Jonathan, Franklin, Alice, Bamford, Rosemary, Hurles, Matthew E., Martin, Hilary C., Mousa, Mahmoud, Rowitch, David H. ... Mill, Jonathan (2025). Cell-type-specific DNA methylation dynamics in the prenatal and postnatal human cortex. Cell Genomics, 5 (12) 101010, 101010. doi: 10.1016/j.xgen.2025.101010 |
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2025 Journal Article Genetic factors predicting risk of mood disorders in adolescentsGangaraju, Swathi Hassan, Middeldorp, Christel M. and Byrne, Enda M. (2025). Genetic factors predicting risk of mood disorders in adolescents. Current Opinion in Psychiatry, 38 (6), 452-457. doi: 10.1097/yco.0000000000001044 |
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2025 Journal Article Defining suicidality phenotypes for genetic studies: perspectives of the Psychiatric Genomics Consortium Suicide Working GroupColbert, Sarah M. C., Monson, Eric T., Andreassen, Ole A., Ayinde, Olatunde O., Barr, Peter B., Bejan, Cosmin A., Ceja, Zuriel, Coon, Hilary, DiBlasi, Emily, Edenberg, Howard J., Gelernter, Joel, Hatoum, Alexander, Izotova, Anastasia, Johnson, Emma C., Kaufman, Erin A., Kranzler, Henry R., Koromina, Maria, Lehto, Kelli, Myung, Woojae, Nurnberger, John I., Serretti, Alessandro, Smoller, Jordan W., Stein, Murray B., Zai, Clement C., Erlangsen, Annette, Gaine, Marie, Martorell, Lourdes, Sud, Reeteka, Toma, Claudio ... Zillich, Lea (2025). Defining suicidality phenotypes for genetic studies: perspectives of the Psychiatric Genomics Consortium Suicide Working Group. Molecular Psychiatry, 30 (12), 1-11. doi: 10.1038/s41380-025-03271-y |
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2025 Journal Article White blood cell proportions are associated with response to psychosocial therapy in young people at ultra-high risk for psychosisBarker, Lauren F., McRae, Allan F., Yuen, Hok Pan, Henders, Anjali K., Wallace, Leanne M., Lin, Tian, Phassouliotis, Christina, Spark, Jessica, Kerr, Melissa, Byrne, Enda M., Amminger, G. Paul, Nelson, Barnaby, Wray, Naomi R. and McGorry, Patrick D. (2025). White blood cell proportions are associated with response to psychosocial therapy in young people at ultra-high risk for psychosis. Biological Psychiatry Global Open Science, 5 (5) 100546, 1-11. doi: 10.1016/j.bpsgos.2025.100546 |
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2025 Journal Article Sex-stratified genome-wide association meta-analysis of major depressive disorderThomas, Jodi T., Thorp, Jackson G., Huider, Floris, Grimes, Poppy Z., Wang, Rujia, Youssef, Pierre, Coleman, Jonathan R. I., Byrne, Enda M., Adams, Mark, BIONIC consortium, van Loo, Hanna M., Penninx, Brenda W. J. H., The GLAD Study, Medland, Sarah E., Hickie, Ian B., Olsen, Catherine M., Whiteman, David C., Whalley, Heather C., Penninx, Brenda W.J.H., van Loo, Hanna M., Derks, Eske M., Eley, Thalia C., Breen, Gerome, Boomsma, Dorret I., Wray, Naomi R., Martin, Nicholas G. and Mitchell, Brittany L. (2025). Sex-stratified genome-wide association meta-analysis of major depressive disorder. Nature Communications, 16 (1) 7960, 1-15. doi: 10.1038/s41467-025-63236-1 |
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2025 Journal Article Genome-wide analyses identify 30 loci associated with obsessive–compulsive disorderStrom, Nora I., Gerring, Zachary F., Galimberti, Marco, Yu, Dongmei, Halvorsen, Matthew W., Abdellaoui, Abdel, Rodriguez-Fontenla, Cristina, Sealock, Julia M., Bigdeli, Tim, Coleman, Jonathan R., Mahjani, Behrang, Thorp, Jackson G., Bey, Katharina, Burton, Christie L., Luykx, Jurjen J., Zai, Gwyneth, Alemany, Silvia, Andre, Christine, Askland, Kathleen D., Bäckman, Julia, Banaj, Nerisa, Barlassina, Cristina, Nissen, Judith Becker, Bienvenu, O. Joseph, Black, Donald, Bloch, Michael H., Børte, Sigrid, Bosch, Rosa, Breen, Michael ... Mattheisen, Manuel (2025). Genome-wide analyses identify 30 loci associated with obsessive–compulsive disorder. Nature Genetics, 57 (6) 230, 1389-1401. doi: 10.1038/s41588-025-02189-z |
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2025 Journal Article Systematic review and meta-analysis: predictors of relapsing, recurrent, and chronic depression in young peopleTagliaferri, Scott D., Han, Laura K.M., Khetan, Muskan, Nguyen, Joshua, Markulev, Connie, Rice, Simon, Cotton, Susan M., Berk, Michael, Byrne, Enda M., Rickwood, Debra, Davey, Christopher G., Koval, Peter, Ratheesh, Aswin, McGorry, Patrick D., Alvarez-Jimenez, Mario and Schmaal, Lianne (2025). Systematic review and meta-analysis: predictors of relapsing, recurrent, and chronic depression in young people. Journal of the American Academy of Child & Adolescent Psychiatry, 65 (2) PMID 8704565, 206-230. doi: 10.1016/j.jaac.2025.03.019 |
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2025 Journal Article Caffeine consumption, psychological distress, and insomnia in a cohort of individuals with depressionMcIntosh, Harry A., Borgas, Aleah J., Aouira, Nisreen, Mitchell, Brittany L., Crouse, Jacob J., Medland, Sarah E., Hickie, Ian B., Wray, Naomi R., Martin, Nicholas G., Middeldorp, Christel M. and Byrne, Enda M. (2025). Caffeine consumption, psychological distress, and insomnia in a cohort of individuals with depression. Complex Psychiatry, 11 (1), 37-49. doi: 10.1159/000545393 |
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2025 Journal Article Markers of positive affect and brain state synchrony discriminate melancholic from non-melancholic depression using naturalistic stimuliMosley, Philip E., van der Meer, Johan N., Hamilton, Lachlan H. W., Fripp, Jurgen, Parker, Stephen, Jeganathan, Jayson, Breakspear, Michael, Parker, Richard, Holland, Rebecca, Mitchell, Brittany L., Byrne, Enda, Hickie, Ian B., Medland, Sarah E., Martin, Nicholas G. and Cocchi, Luca (2025). Markers of positive affect and brain state synchrony discriminate melancholic from non-melancholic depression using naturalistic stimuli. Molecular Psychiatry, 30 (3) 11605, 848-860. doi: 10.1038/s41380-024-02699-y |
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2025 Journal Article Improving Outcomes in Mental Health (IOMH)—an Australian longitudinal clinical study of families with children with neurodevelopmental problems: cohort profileGalligan, Dana E, Payne, Leanne, Sullivan, Daniel P., Bhadravathi Lokeshappa, Madhura, Ziser, Laura, Nunn, Lorelle, Wallace, Leanne M., Andersen, Isabella, Howarth, Sophie, Kato, Akina, Karunanithi, Mohan, Mingin, Cassandra, O’Scanaill, Sally, Aouira, Nisreen, Paramecwari, Ayu, Sanders, Matthew R., Cobham, Vanessa E., Wray, Naomi R., Henders, Anjali K., Byrne, Enda M., Heussler, Honey and Middeldorp, Christel M. (2025). Improving Outcomes in Mental Health (IOMH)—an Australian longitudinal clinical study of families with children with neurodevelopmental problems: cohort profile. BMJ Open, 15 (3) e091676, 1-12. doi: 10.1136/bmjopen-2024-091676 |
