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2023

Journal Article

GWAS meta-analysis of suicide attempt: identification of 12 genome-wide significant loci and implication of genetic risks for specific health factors

Docherty, Anna R., Mullins, Niamh, Ashley-Koch, Allison E., Qin, Xuejun, Coleman, Jonathan R.I., Shabalin, Andrey, Kang, JooEun, Murnyak, Balasz, Wendt, Frank, Adams, Mark, Campos, Adrian I., DiBlasi, Emily, Fullerton, Janice M., Kranzler, Henry R., Bakian, Amanda V., Monson, Eric T., Rentería, Miguel E., Walss-Bass, Consuelo, Andreassen, Ole A., Behera, Chittaranjan, Bulik, Cynthia M., Edenberg, Howard J., Kessler, Ronald C., Mann, J. John, Nurnberger, John I., Pistis, Giorgio, Streit, Fabian, Ursano, Robert J., Polimanti, Renato ... German Borderline Genomics Consortium (2023). GWAS meta-analysis of suicide attempt: identification of 12 genome-wide significant loci and implication of genetic risks for specific health factors. American Journal of Psychiatry, 180 (10), 723-738. doi: 10.1176/appi.ajp.21121266

GWAS meta-analysis of suicide attempt: identification of 12 genome-wide significant loci and implication of genetic risks for specific health factors

2023

Journal Article

Using electronic health record data to predict future self‐harm or suicidal ideation in young people treated by child and youth mental health services

Tennakoon, Gayani, Byrne, Enda M., Vaithianathan, Rhema and Middeldorp, Christel M. (2023). Using electronic health record data to predict future self‐harm or suicidal ideation in young people treated by child and youth mental health services. Suicide and Life-Threatening Behavior, 53 (5), 853-869. doi: 10.1111/sltb.12988

Using electronic health record data to predict future self‐harm or suicidal ideation in young people treated by child and youth mental health services

2023

Journal Article

The association between trauma exposure, polygenic risk and individual depression symptoms

Thorp, Jackson G., Gerring, Zachary F., Colodro-Conde, Lucía, Byrne, Enda M., Medland, Sarah E., Middeldorp, Christel M. and Derks, Eske M. (2023). The association between trauma exposure, polygenic risk and individual depression symptoms. Psychiatry Research, 321 115101, 1-8. doi: 10.1016/j.psychres.2023.115101

The association between trauma exposure, polygenic risk and individual depression symptoms

2023

Journal Article

Polygenic risk scores and the prediction of onset of mood and psychotic disorders in adolescents and young adults

Scott, Jan, Crouse, Jacob J., Medland, Sarah, Byrne, Enda, Iorfino, Frank, Mitchell, Brittany, Gillespie, Nathan A., Martin, Nicholas, Wray, Naomi and Hickie, Ian B. (2023). Polygenic risk scores and the prediction of onset of mood and psychotic disorders in adolescents and young adults. Early Intervention in Psychiatry, 18 (6), 397-405. doi: 10.1111/eip.13472

Polygenic risk scores and the prediction of onset of mood and psychotic disorders in adolescents and young adults

2022

Journal Article

Phenotypic and genetic factors associated with donation of DNA and consent to record linkage for prescription history in the Australian Genetics of Depression Study

Gomez, Lina, Díaz-Torres, Santiago, Colodro-Conde, Lucía, Garcia-Marin, Luis M., Yap, Chloe X., Byrne, Enda M., Yengo, Loic, Lind, Penelope A., Wray, Naomi R., Medland, Sarah E., Hickie, Ian B., Lupton, Michelle K., Rentería, Miguel E., Martin, Nicholas G. and Campos, Adrian I. (2022). Phenotypic and genetic factors associated with donation of DNA and consent to record linkage for prescription history in the Australian Genetics of Depression Study. European Archives of Psychiatry and Clinical Neuroscience, 273 (6), 1359-1368. doi: 10.1007/s00406-022-01527-0

Phenotypic and genetic factors associated with donation of DNA and consent to record linkage for prescription history in the Australian Genetics of Depression Study

2022

Journal Article

Corrigendum: Potential genetic overlap between insomnia and sleep symptoms in major depressive disorder: A polygenic risk score analysis(Front. Psychiatry, (2021), 12, (734077), 10.3389/fpsyt.2021.734077)

Melhuish Beaupre, Lindsay M., Tiwari, Arun K., Gonçalves, Vanessa F., Zai, Clement C., Marshe, Victoria S., Lewis, Cathryn M., Martin, Nicholas G., McIntosh, Andrew M., Adams, Mark J., Baune, Bernhard T., Levinson, Doug F., Boomsma, Dorret I., Penninx, Brenda W. J. H., Breen, Gerome, Hamilton, Steve, Awasthi, Swapnil, Ripke, Stephan, Jones, Lisa, Jones, Ian, Byrne, Enda M., Hickie, Ian B., Potash, James P., Shi, Jianxin, Weissman, Myrna M., Milaneschi, Yuri, Shyn, Stanley I., Geus, Eco J. C. de, Willemsen, Gonneke, Brown, Gregory M. and Kennedy, James L. (2022). Corrigendum: Potential genetic overlap between insomnia and sleep symptoms in major depressive disorder: A polygenic risk score analysis(Front. Psychiatry, (2021), 12, (734077), 10.3389/fpsyt.2021.734077). Frontiers in Psychiatry, 13 893816, 893816. doi: 10.3389/fpsyt.2022.893816

Corrigendum: Potential genetic overlap between insomnia and sleep symptoms in major depressive disorder: A polygenic risk score analysis(Front. Psychiatry, (2021), 12, (734077), 10.3389/fpsyt.2021.734077)

2022

Journal Article

Clinical, demographic, and genetic risk factors of treatment‐attributed suicidality in >10,000 Australian adults taking antidepressants

Campos, Adrian I., Byrne, Enda M., Iorfino, Frank, Fabbri, Chiara, Hickie, Ian B., Lewis, Cathryn M., Wray, Naomi R., Medland, Sarah E., Rentería, Miguel E. and Martin, Nicholas G. (2022). Clinical, demographic, and genetic risk factors of treatment‐attributed suicidality in >10,000 Australian adults taking antidepressants. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 189 (6), 196-206. doi: 10.1002/ajmg.b.32913

Clinical, demographic, and genetic risk factors of treatment‐attributed suicidality in >10,000 Australian adults taking antidepressants

2022

Journal Article

Lifetime prevalence and correlates of perinatal depression in a case-cohort study of depression

Kiewa, Jacqueline, Meltzer-Brody, Samantha, Milgrom, Jeannette, Bennett, Elizabeth, Mackle, Tracey, Guintivano, Jerry, Hickie, Ian B, Colodro-Conde, Lucia, Medland, Sarah E, Martin, Nick, Wray, Naomi and Byrne, Enda (2022). Lifetime prevalence and correlates of perinatal depression in a case-cohort study of depression. BMJ Open, 12 (8) e059300, 1-7. doi: 10.1136/bmjopen-2021-059300

Lifetime prevalence and correlates of perinatal depression in a case-cohort study of depression

2022

Journal Article

Dynamic networks of psychological symptoms, impairment, substance use, and social support: the evolution of psychopathology among emerging adults

Crouse, Jacob J., Ho, Nicholas, Scott, Jan, Parker, Richard, Park, Shin Ho, Couvy-Duchesne, Baptiste, Mitchell, Brittany, Byrne, Enda M., Hermens, Daniel F., Medland, Sarah E., Martin, Nicholas G., Gillespie, Nathan A. and Hickie, Ian B. (2022). Dynamic networks of psychological symptoms, impairment, substance use, and social support: the evolution of psychopathology among emerging adults. European Psychiatry, 65 (1) e32, 1-24. doi: 10.1192/j.eurpsy.2022.23

Dynamic networks of psychological symptoms, impairment, substance use, and social support: the evolution of psychopathology among emerging adults

2022

Journal Article

Multi-trait genetic analysis identifies auto-immune loci associated with cutaneous melanoma

Liyanage, Upekha, MacGregor, Stuart, Bishop, D. Timothy, Shi, Jianxin, An, Jiyuan, Ong, Jue Sheng, Han, Xikun, Scolyer, Richard A., Martin, Nicholas G., Medland, Sarah E., Byrne, Enda M., Green, Adèle C., Saw, Robyn P. M., Thompson, John F., Stretch, Jonathan, Spillane, Andrew, Jiang, Yunxuan, Tian, Chao, 23andMe Research Team, Gordon, Scott G., Duffy, David L., Olsen, Catherine M., Whiteman, David C., Long, Georgina V., Iles, Mark M., Landi, Maria Teresa and Law, Matthew H. (2022). Multi-trait genetic analysis identifies auto-immune loci associated with cutaneous melanoma. The Journal of Investigative Dermatology, 142 (6), 1607-1616. doi: 10.1016/j.jid.2021.08.449

Multi-trait genetic analysis identifies auto-immune loci associated with cutaneous melanoma

2022

Journal Article

Identifying the Common Genetic Basis of Antidepressant Response

Pain, Oliver, Hodgson, Karen, Trubetskoy, Vassily, Ripke, Stephan, Marshe, Victoria S., Adams, Mark J., Byrne, Enda M., Campos, Adrian I., Carrillo-Roa, Tania, Cattaneo, Annamaria, Als, Thomas D., Souery, Daniel, Dernovsek, Mojca Z., Fabbri, Chiara, Hayward, Caroline, Henigsberg, Neven, Hauser, Joanna, Kennedy, James L., Lenze, Eric J., Lewis, Glyn, Müller, Daniel J., Martin, Nicholas G., Mulsant, Benoit H., Mors, Ole, Perroud, Nader, Porteous, David J., Rentería, Miguel E., Reynolds, Charles F., Rietschel, Marcella ... Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2022). Identifying the Common Genetic Basis of Antidepressant Response. Biological Psychiatry Global Open Science, 2 (2), 115-126. doi: 10.1016/j.bpsgos.2021.07.008

Identifying the Common Genetic Basis of Antidepressant Response

2022

Journal Article

Perinatal depression is associated with a higher polygenic risk for major depressive disorder than non-perinatal depression

Kiewa, Jacqueline, Meltzer‐Brody, Samantha, Milgrom, Jeanette, Guintivano, Jerry, Hickie, Ian B., Whiteman, David C., Olsen, Catherine M., Colodro‐Conde, Lucía, Medland, Sarah E., Martin, Nicholas G., Wray, Naomi R. and Byrne, Enda M. (2022). Perinatal depression is associated with a higher polygenic risk for major depressive disorder than non-perinatal depression. Depression and Anxiety, 39 (3), 182-191. doi: 10.1002/da.23232

Perinatal depression is associated with a higher polygenic risk for major depressive disorder than non-perinatal depression

2022

Journal Article

Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders, and known risk factors

Mullins, Niamh, Kang, JooEun, Campos, Adrian I., Coleman, Jonathan R I, Edwards, Alexis C., Galfalvy, Hanga, Levey, Daniel F., Lori, Adriana, Shabalin, Andrey, Starnawska, Anna, Su, Mei-Hsin, Watson, Hunna J., Adams, Mark, Awasthi, Swapnil, Gandal, Michael, Hafferty, Jonathan D., Hishimoto, Akitoyo, Kim, Minsoo, Okazaki, Satoshi, Otsuka, Ikuo, Ripke, Stephan, Ware, Erin B., Bergen, Andrew W., Berrettini, Wade H., Bohus, Martin, Brandt, Harry, Chang, Xiao, Chen, Wei J., Chen, Hsi-Chung ... Ruderfer, Douglas M. (2022). Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders, and known risk factors. Biological Psychiatry, 91 (3), 313-327. doi: 10.1016/j.biopsych.2021.05.029

Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders, and known risk factors

2022

Journal Article

Impact of CYP2C19 metaboliser status on SSRI response: a retrospective study of 9500 participants of the Australian Genetics of Depression Study

Campos, Adrian I., Byrne, Enda M., Mitchell, Brittany L., Wray, Naomi R., Lind, Penelope A., Licinio, Julio, Medland, Sarah E., Martin, Nicholas G., Hickie, Ian B. and Rentería, Miguel E. (2022). Impact of CYP2C19 metaboliser status on SSRI response: a retrospective study of 9500 participants of the Australian Genetics of Depression Study. The Pharmacogenomics Journal, 22 (2), 130-135. doi: 10.1038/s41397-022-00267-7

Impact of CYP2C19 metaboliser status on SSRI response: a retrospective study of 9500 participants of the Australian Genetics of Depression Study

2021

Journal Article

Potential genetic overlap between insomnia and sleep symptoms in major depressive disorder: a polygenic risk score analysis

Melhuish Beaupre, Lindsay M., Tiwari, Arun K., Gonçalves, Vanessa F., Zai, Clement C., Marshe, Victoria S., Lewis, Cathryn M., Martin, Nicholas G., McIntosh, Andrew M., Adams, Mark J., Baune, Bernhard T., Levinson, Doug F., Boomsma, Dorret I., Penninx, Brenda W. J. H., Breen, Gerome, Hamilton, Steve, Awasthi, Swapnil, Ripke, Stephan, Jones, Lisa, Jones, Ian, Byrne, Enda M., Hickie, Ian B., Potash, James P., Shi, Jianxin, Weissman, Myrna M., Milaneschi, Yuri, Shyn, Stanley I., Geus, Eco J. C. de, Willemsen, Gonneke, Brown, Gregory M. and Kennedy, James L. (2021). Potential genetic overlap between insomnia and sleep symptoms in major depressive disorder: a polygenic risk score analysis. Frontiers in Psychiatry, 12 734077, 734077. doi: 10.3389/fpsyt.2021.734077

Potential genetic overlap between insomnia and sleep symptoms in major depressive disorder: a polygenic risk score analysis

2021

Journal Article

Understanding genetic risk factors for common side effects of antidepressant medications

Campos, Adrian I., Mulcahy, Aoibhe, Thorp, Jackson G., Wray, Naomi R., Byrne, Enda M., Lind, Penelope A., Medland, Sarah E., Martin, Nicholas G., Hickie, Ian B. and Rentería, Miguel E. (2021). Understanding genetic risk factors for common side effects of antidepressant medications. Communications Medicine, 1 (1) 45, 1-10. doi: 10.1038/s43856-021-00046-8

Understanding genetic risk factors for common side effects of antidepressant medications

2021

Journal Article

The Australian Genetics of Depression Study: new risk loci and dissecting heterogeneity between subtypes

Mitchell, Brittany L., Campos, Adrian I., Whiteman, David C., Olsen, Catherine M., Gordon, Scott D., Walker, Adam J., Dean, Olivia M., Berk, Michael, Hickie, Ian B., Medland, Sarah E., Wray, Naomi R., Martin, Nicholas G. and Byrne, Enda M. (2021). The Australian Genetics of Depression Study: new risk loci and dissecting heterogeneity between subtypes. Biological Psychiatry, 92 (3), 227-235. doi: 10.1016/j.biopsych.2021.10.021

The Australian Genetics of Depression Study: new risk loci and dissecting heterogeneity between subtypes

2021

Journal Article

Genetic and environmental influences on sleep-wake behaviours in adolescence

O'Callaghan, Victoria S., Hansell, Narelle K., Guo, Wei, Carpenter, Joanne S., Shou, Haochang, Strike, Lachlan T., Crouse, Jacob J., McAloney, Kerrie, McMahon, Katie L., Byrne, Enda M., Burns, Jane M., Martin, Nicholas G., Hickie, Ian B., Merikangas, Kathleen R. and Wright, Margaret J. (2021). Genetic and environmental influences on sleep-wake behaviours in adolescence. Sleep Advances, 2 (1) zpab018, zpab018. doi: 10.1093/sleepadvances/zpab018

Genetic and environmental influences on sleep-wake behaviours in adolescence

2021

Journal Article

Transcriptome-based polygenic score links depression-related corticolimbic gene expression changes to sex-specific brain morphology and depression risk

Miles, Amy E., Dos Santos, Fernanda C., Byrne, Enda M., Renteria, Miguel E., McIntosh, Andrew M., Adams, Mark J., Pistis, Giorgio, Castelao, Enrique, Preisig, Martin, Baune, Bernhard T., Schubert, K. Oliver, Lewis, Cathryn M., Jones, Lisa A., Jones, Ian, Uher, Rudolf, Smoller, Jordan W., Perlis, Roy H., Levinson, Douglas F., Potash, James B., Weissman, Myrna M., Shi, Jianxin, Lewis, Glyn, Penninx, Brenda W. J. H., Boomsma, Dorret I., Hamilton, Steven P., Sibille, Etienne, Hariri, Ahmad R., Nikolova, Yuliya S. and Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2021). Transcriptome-based polygenic score links depression-related corticolimbic gene expression changes to sex-specific brain morphology and depression risk. Neuropsychopharmacology, 46 (13), 2304-2311. doi: 10.1038/s41386-021-01189-x

Transcriptome-based polygenic score links depression-related corticolimbic gene expression changes to sex-specific brain morphology and depression risk

2021

Journal Article

Polygenic risk scores derived from varying definitions of depression and risk of depression

Mitchell, Brittany L., Thorp, Jackson G., Wu, Yeda, Campos, Adrian I., Nyholt, Dale R., Gordon, Scott D., Whiteman, David C., Olsen, Catherine M., Hickie, Ian B., Martin, Nicholas G., Medland, Sarah E., Wray, Naomi R. and Byrne, Enda M. (2021). Polygenic risk scores derived from varying definitions of depression and risk of depression. JAMA Psychiatry, 78 (10), 1152-1160. doi: 10.1001/jamapsychiatry.2021.1988

Polygenic risk scores derived from varying definitions of depression and risk of depression