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2022

Journal Article

Dynamic networks of psychological symptoms, impairment, substance use, and social support: the evolution of psychopathology among emerging adults

Crouse, Jacob J., Ho, Nicholas, Scott, Jan, Parker, Richard, Park, Shin Ho, Couvy-Duchesne, Baptiste, Mitchell, Brittany, Byrne, Enda M., Hermens, Daniel F., Medland, Sarah E., Martin, Nicholas G., Gillespie, Nathan A. and Hickie, Ian B. (2022). Dynamic networks of psychological symptoms, impairment, substance use, and social support: the evolution of psychopathology among emerging adults. European Psychiatry, 65 (1) e32, 1-24. doi: 10.1192/j.eurpsy.2022.23

Dynamic networks of psychological symptoms, impairment, substance use, and social support: the evolution of psychopathology among emerging adults

2022

Journal Article

Multi-trait genetic analysis identifies auto-immune loci associated with cutaneous melanoma

Liyanage, Upekha, MacGregor, Stuart, Bishop, D. Timothy, Shi, Jianxin, An, Jiyuan, Ong, Jue Sheng, Han, Xikun, Scolyer, Richard A., Martin, Nicholas G., Medland, Sarah E., Byrne, Enda M., Green, Adèle C., Saw, Robyn P. M., Thompson, John F., Stretch, Jonathan, Spillane, Andrew, Jiang, Yunxuan, Tian, Chao, 23andMe Research Team, Gordon, Scott G., Duffy, David L., Olsen, Catherine M., Whiteman, David C., Long, Georgina V., Iles, Mark M., Landi, Maria Teresa and Law, Matthew H. (2022). Multi-trait genetic analysis identifies auto-immune loci associated with cutaneous melanoma. The Journal of Investigative Dermatology, 142 (6), 1607-1616. doi: 10.1016/j.jid.2021.08.449

Multi-trait genetic analysis identifies auto-immune loci associated with cutaneous melanoma

2022

Journal Article

Identifying the Common Genetic Basis of Antidepressant Response

Pain, Oliver, Hodgson, Karen, Trubetskoy, Vassily, Ripke, Stephan, Marshe, Victoria S., Adams, Mark J., Byrne, Enda M., Campos, Adrian I., Carrillo-Roa, Tania, Cattaneo, Annamaria, Als, Thomas D., Souery, Daniel, Dernovsek, Mojca Z., Fabbri, Chiara, Hayward, Caroline, Henigsberg, Neven, Hauser, Joanna, Kennedy, James L., Lenze, Eric J., Lewis, Glyn, Müller, Daniel J., Martin, Nicholas G., Mulsant, Benoit H., Mors, Ole, Perroud, Nader, Porteous, David J., Rentería, Miguel E., Reynolds, Charles F., Rietschel, Marcella ... Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2022). Identifying the Common Genetic Basis of Antidepressant Response. Biological Psychiatry Global Open Science, 2 (2), 115-126. doi: 10.1016/j.bpsgos.2021.07.008

Identifying the Common Genetic Basis of Antidepressant Response

2022

Journal Article

Perinatal depression is associated with a higher polygenic risk for major depressive disorder than non-perinatal depression

Kiewa, Jacqueline, Meltzer‐Brody, Samantha, Milgrom, Jeanette, Guintivano, Jerry, Hickie, Ian B., Whiteman, David C., Olsen, Catherine M., Colodro‐Conde, Lucía, Medland, Sarah E., Martin, Nicholas G., Wray, Naomi R. and Byrne, Enda M. (2022). Perinatal depression is associated with a higher polygenic risk for major depressive disorder than non-perinatal depression. Depression and Anxiety, 39 (3), 182-191. doi: 10.1002/da.23232

Perinatal depression is associated with a higher polygenic risk for major depressive disorder than non-perinatal depression

2022

Journal Article

Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders, and known risk factors

Mullins, Niamh, Kang, JooEun, Campos, Adrian I., Coleman, Jonathan R I, Edwards, Alexis C., Galfalvy, Hanga, Levey, Daniel F., Lori, Adriana, Shabalin, Andrey, Starnawska, Anna, Su, Mei-Hsin, Watson, Hunna J., Adams, Mark, Awasthi, Swapnil, Gandal, Michael, Hafferty, Jonathan D., Hishimoto, Akitoyo, Kim, Minsoo, Okazaki, Satoshi, Otsuka, Ikuo, Ripke, Stephan, Ware, Erin B., Bergen, Andrew W., Berrettini, Wade H., Bohus, Martin, Brandt, Harry, Chang, Xiao, Chen, Wei J., Chen, Hsi-Chung ... Ruderfer, Douglas M. (2022). Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders, and known risk factors. Biological Psychiatry, 91 (3), 313-327. doi: 10.1016/j.biopsych.2021.05.029

Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders, and known risk factors

2022

Journal Article

Impact of CYP2C19 metaboliser status on SSRI response: a retrospective study of 9500 participants of the Australian Genetics of Depression Study

Campos, Adrian I., Byrne, Enda M., Mitchell, Brittany L., Wray, Naomi R., Lind, Penelope A., Licinio, Julio, Medland, Sarah E., Martin, Nicholas G., Hickie, Ian B. and Rentería, Miguel E. (2022). Impact of CYP2C19 metaboliser status on SSRI response: a retrospective study of 9500 participants of the Australian Genetics of Depression Study. The Pharmacogenomics Journal, 22 (2), 130-135. doi: 10.1038/s41397-022-00267-7

Impact of CYP2C19 metaboliser status on SSRI response: a retrospective study of 9500 participants of the Australian Genetics of Depression Study

2021

Journal Article

Potential genetic overlap between insomnia and sleep symptoms in major depressive disorder: a polygenic risk score analysis

Melhuish Beaupre, Lindsay M., Tiwari, Arun K., Gonçalves, Vanessa F., Zai, Clement C., Marshe, Victoria S., Lewis, Cathryn M., Martin, Nicholas G., McIntosh, Andrew M., Adams, Mark J., Baune, Bernhard T., Levinson, Doug F., Boomsma, Dorret I., Penninx, Brenda W. J. H., Breen, Gerome, Hamilton, Steve, Awasthi, Swapnil, Ripke, Stephan, Jones, Lisa, Jones, Ian, Byrne, Enda M., Hickie, Ian B., Potash, James P., Shi, Jianxin, Weissman, Myrna M., Milaneschi, Yuri, Shyn, Stanley I., Geus, Eco J. C. de, Willemsen, Gonneke, Brown, Gregory M. and Kennedy, James L. (2021). Potential genetic overlap between insomnia and sleep symptoms in major depressive disorder: a polygenic risk score analysis. Frontiers in Psychiatry, 12 734077, 734077. doi: 10.3389/fpsyt.2021.734077

Potential genetic overlap between insomnia and sleep symptoms in major depressive disorder: a polygenic risk score analysis

2021

Journal Article

Understanding genetic risk factors for common side effects of antidepressant medications

Campos, Adrian I., Mulcahy, Aoibhe, Thorp, Jackson G., Wray, Naomi R., Byrne, Enda M., Lind, Penelope A., Medland, Sarah E., Martin, Nicholas G., Hickie, Ian B. and Rentería, Miguel E. (2021). Understanding genetic risk factors for common side effects of antidepressant medications. Communications Medicine, 1 (1) 45, 1-10. doi: 10.1038/s43856-021-00046-8

Understanding genetic risk factors for common side effects of antidepressant medications

2021

Journal Article

The Australian Genetics of Depression Study: new risk loci and dissecting heterogeneity between subtypes

Mitchell, Brittany L., Campos, Adrian I., Whiteman, David C., Olsen, Catherine M., Gordon, Scott D., Walker, Adam J., Dean, Olivia M., Berk, Michael, Hickie, Ian B., Medland, Sarah E., Wray, Naomi R., Martin, Nicholas G. and Byrne, Enda M. (2021). The Australian Genetics of Depression Study: new risk loci and dissecting heterogeneity between subtypes. Biological Psychiatry, 92 (3), 227-235. doi: 10.1016/j.biopsych.2021.10.021

The Australian Genetics of Depression Study: new risk loci and dissecting heterogeneity between subtypes

2021

Journal Article

Genetic and environmental influences on sleep-wake behaviours in adolescence

O'Callaghan, Victoria S., Hansell, Narelle K., Guo, Wei, Carpenter, Joanne S., Shou, Haochang, Strike, Lachlan T., Crouse, Jacob J., McAloney, Kerrie, McMahon, Katie L., Byrne, Enda M., Burns, Jane M., Martin, Nicholas G., Hickie, Ian B., Merikangas, Kathleen R. and Wright, Margaret J. (2021). Genetic and environmental influences on sleep-wake behaviours in adolescence. Sleep Advances, 2 (1) zpab018, zpab018. doi: 10.1093/sleepadvances/zpab018

Genetic and environmental influences on sleep-wake behaviours in adolescence

2021

Journal Article

Transcriptome-based polygenic score links depression-related corticolimbic gene expression changes to sex-specific brain morphology and depression risk

Miles, Amy E., Dos Santos, Fernanda C., Byrne, Enda M., Renteria, Miguel E., McIntosh, Andrew M., Adams, Mark J., Pistis, Giorgio, Castelao, Enrique, Preisig, Martin, Baune, Bernhard T., Schubert, K. Oliver, Lewis, Cathryn M., Jones, Lisa A., Jones, Ian, Uher, Rudolf, Smoller, Jordan W., Perlis, Roy H., Levinson, Douglas F., Potash, James B., Weissman, Myrna M., Shi, Jianxin, Lewis, Glyn, Penninx, Brenda W. J. H., Boomsma, Dorret I., Hamilton, Steven P., Sibille, Etienne, Hariri, Ahmad R., Nikolova, Yuliya S. and Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2021). Transcriptome-based polygenic score links depression-related corticolimbic gene expression changes to sex-specific brain morphology and depression risk. Neuropsychopharmacology, 46 (13), 2304-2311. doi: 10.1038/s41386-021-01189-x

Transcriptome-based polygenic score links depression-related corticolimbic gene expression changes to sex-specific brain morphology and depression risk

2021

Journal Article

Polygenic risk scores derived from varying definitions of depression and risk of depression

Mitchell, Brittany L., Thorp, Jackson G., Wu, Yeda, Campos, Adrian I., Nyholt, Dale R., Gordon, Scott D., Whiteman, David C., Olsen, Catherine M., Hickie, Ian B., Martin, Nicholas G., Medland, Sarah E., Wray, Naomi R. and Byrne, Enda M. (2021). Polygenic risk scores derived from varying definitions of depression and risk of depression. JAMA Psychiatry, 78 (10), 1152-1160. doi: 10.1001/jamapsychiatry.2021.1988

Polygenic risk scores derived from varying definitions of depression and risk of depression

2021

Journal Article

Genetic risk for chronic pain is associated with lower antidepressant effectiveness: converging evidence for a depression subtype

Campos, Adrián I., Ngo, Trung Thanh, Medland, Sarah E., Wray, Naomi R., Hickie, Ian B., Byrne, Enda M., Martin, Nicholas G. and Rentería, Miguel E. (2021). Genetic risk for chronic pain is associated with lower antidepressant effectiveness: converging evidence for a depression subtype. Australian and New Zealand Journal of Psychiatry, 56 (9) 00048674211031491, 1-10. doi: 10.1177/00048674211031491

Genetic risk for chronic pain is associated with lower antidepressant effectiveness: converging evidence for a depression subtype

2021

Journal Article

Examining sex-differentiated genetic effects across neuropsychiatric and behavioral traits

Martin, Joanna, Khramtsova, Ekaterina A., Goleva, Slavina B., Blokland, Gabriëlla A.M., Traglia, Michela, Walters, Raymond K., Hübel, Christopher, Coleman, Jonathan R.I., Breen, Gerome, Børglum, Anders D., Demontis, Ditte, Grove, Jakob, Werge, Thomas, Bralten, Janita, Bulik, Cynthia M., Lee, Phil H., Mathews, Carol A., Peterson, Roseann E., Winham, Stacey J., Wray, Naomi, Edenberg, Howard J., Guo, Wei, Yao, Yin, Neale, Benjamin M., Faraone, Stephen V., Petryshen, Tracey L., Weiss, Lauren A., Duncan, Laramie E., Goldstein, Jill M. ... Stahl, Eli (2021). Examining sex-differentiated genetic effects across neuropsychiatric and behavioral traits. Biological Psychiatry, 89 (12), 1127-1137. doi: 10.1016/j.biopsych.2020.12.024

Examining sex-differentiated genetic effects across neuropsychiatric and behavioral traits

2021

Journal Article

Erratum: Alzheimer's disease genetic risk and sleep phenotypes in healthy young men: Association with more slow waves and daytime sleepiness (SLEEP DOI: 10.1093/sleep/zsaa137)

Muto, Vincenzo, Koshmanova, Ekaterina, Ghaemmaghami, Pouya, Jaspar, Mathieu, Meyer, Christelle, Elansary, Mahmoud, Van Egroo, Maxime, Chylinski, Daphne, Berthomier, Christian, Brandewinder, Marie, Mouraux, Charlotte, Schmidt, Christina, Hammad, Gregory, Coppieters, Wouter, Ahariz, Naima, Degueldre, Christian, Luxen, Andre, Salmon, Eric, Phillips, Christophe, Archer, Simon N, Yengo, Loic, Byrne, Enda, Collette, Fabienne, Georges, Michel, Dijk, Derk-Jan, Maquet, Pierre, Visscher, Peter M and Vandewalle, Gilles (2021). Erratum: Alzheimer's disease genetic risk and sleep phenotypes in healthy young men: Association with more slow waves and daytime sleepiness (SLEEP DOI: 10.1093/sleep/zsaa137). Sleep, 44 (5) zsaa137. doi: 10.1093/sleep/zsab079

Erratum: Alzheimer's disease genetic risk and sleep phenotypes in healthy young men: Association with more slow waves and daytime sleepiness (SLEEP DOI: 10.1093/sleep/zsaa137)

2021

Journal Article

Symptom-level modelling unravels the shared genetic architecture of anxiety and depression

Thorp, Jackson G., Campos, Adrian I., Grotzinger, Andrew D., Gerring, Zachary F., An, Jiyuan, Ong, Jue-Sheng, Wang, Wei, Shringarpure, Suyash, Byrne, Enda M., MacGregor, Stuart, Martin, Nicholas G., Medland, Sarah E., Middeldorp, Christel M. and Derks, Eske M. (2021). Symptom-level modelling unravels the shared genetic architecture of anxiety and depression. Nature Human Behaviour, 5 (10), 1432-1442. doi: 10.1038/s41562-021-01094-9

Symptom-level modelling unravels the shared genetic architecture of anxiety and depression

2021

Journal Article

Comorbid chronic pain and depression: shared risk factors and differential antidepressant effectiveness

Roughan, William H., Campos, Adrián I., García-Marín, Luis M., Cuéllar-Partida, Gabriel, Lupton, Michelle K., Hickie, Ian B., Medland, Sarah E., Wray, Naomi R., Byrne, Enda M., Ngo, Trung Thanh, Martin, Nicholas G. and Rentería, Miguel E. (2021). Comorbid chronic pain and depression: shared risk factors and differential antidepressant effectiveness. Frontiers in Psychiatry, 12 643609, 1-13. doi: 10.3389/fpsyt.2021.643609

Comorbid chronic pain and depression: shared risk factors and differential antidepressant effectiveness

2021

Journal Article

Can network analysis of self-reported psychopathology shed light on the core phenomenology of bipolar disorders in adolescents and young adults?

Scott, Jan, Crouse, Jacob J., Ho, Nicholas, Carpenter, Joanne, Martin, Nicholas, Medland, Sarah, Parker, Richard, Byrne, Enda, Couvy-Duchesne, Baptiste, Mitchell, Brittany, Merikangas, Kathleen, Gillespie, Nathan A. and Hickie, Ian (2021). Can network analysis of self-reported psychopathology shed light on the core phenomenology of bipolar disorders in adolescents and young adults?. Bipolar Disorders, 23 (6), 584-594. doi: 10.1111/bdi.13067

Can network analysis of self-reported psychopathology shed light on the core phenomenology of bipolar disorders in adolescents and young adults?

2021

Journal Article

GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression

Wu, Yeda, Murray, Graham K., Byrne, Enda M., Sidorenko, Julia, Visscher, Peter M. and Wray, Naomi R. (2021). GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression. Nature Communications, 12 (1) 1146, 1-17. doi: 10.1038/s41467-021-21280-7

GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression

2021

Journal Article

Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

Blokland, Gabriëlla A.M., Grove, Jakob, Chen, Chia-Yen, Cotsapas, Chris, Tobet, Stuart, Handa, Robert, Ripke, Stephan, Neale, Benjamin M., Corvin, Aiden, Walters, James T.R., Farh, Kai-How, Holmans, Peter A., Lee, Phil, Bulik-Sullivan, Brendan, Collier, David A., Huang, Hailiang, Pers, Tune H., Agartz, Ingrid, Agerbo, Esben, Albus, Margot, Alexander, Madeline, Amin, Farooq, Bacanu, Silviu A., Begemann, Martin, Belliveau, Richard A., Bene, Judit, Bergen, Sarah E., Bevilacqua, Elizabeth, Bigdeli, Tim B. ... iPSYCH (2021). Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Biological Psychiatry, 91 (1), 102-117. doi: 10.1016/j.biopsych.2021.02.972

Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders