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2021

Journal Article

Genetic risk for chronic pain is associated with lower antidepressant effectiveness: converging evidence for a depression subtype

Campos, Adrián I., Ngo, Trung Thanh, Medland, Sarah E., Wray, Naomi R., Hickie, Ian B., Byrne, Enda M., Martin, Nicholas G. and Rentería, Miguel E. (2021). Genetic risk for chronic pain is associated with lower antidepressant effectiveness: converging evidence for a depression subtype. Australian and New Zealand Journal of Psychiatry, 56 (9) 00048674211031491, 1-10. doi: 10.1177/00048674211031491

Genetic risk for chronic pain is associated with lower antidepressant effectiveness: converging evidence for a depression subtype

2021

Journal Article

Examining sex-differentiated genetic effects across neuropsychiatric and behavioral traits

Martin, Joanna, Khramtsova, Ekaterina A., Goleva, Slavina B., Blokland, Gabriëlla A.M., Traglia, Michela, Walters, Raymond K., Hübel, Christopher, Coleman, Jonathan R.I., Breen, Gerome, Børglum, Anders D., Demontis, Ditte, Grove, Jakob, Werge, Thomas, Bralten, Janita, Bulik, Cynthia M., Lee, Phil H., Mathews, Carol A., Peterson, Roseann E., Winham, Stacey J., Wray, Naomi, Edenberg, Howard J., Guo, Wei, Yao, Yin, Neale, Benjamin M., Faraone, Stephen V., Petryshen, Tracey L., Weiss, Lauren A., Duncan, Laramie E., Goldstein, Jill M. ... Stahl, Eli (2021). Examining sex-differentiated genetic effects across neuropsychiatric and behavioral traits. Biological Psychiatry, 89 (12), 1127-1137. doi: 10.1016/j.biopsych.2020.12.024

Examining sex-differentiated genetic effects across neuropsychiatric and behavioral traits

2021

Journal Article

Erratum: Alzheimer's disease genetic risk and sleep phenotypes in healthy young men: Association with more slow waves and daytime sleepiness (SLEEP DOI: 10.1093/sleep/zsaa137)

Muto, Vincenzo, Koshmanova, Ekaterina, Ghaemmaghami, Pouya, Jaspar, Mathieu, Meyer, Christelle, Elansary, Mahmoud, Van Egroo, Maxime, Chylinski, Daphne, Berthomier, Christian, Brandewinder, Marie, Mouraux, Charlotte, Schmidt, Christina, Hammad, Gregory, Coppieters, Wouter, Ahariz, Naima, Degueldre, Christian, Luxen, Andre, Salmon, Eric, Phillips, Christophe, Archer, Simon N, Yengo, Loic, Byrne, Enda, Collette, Fabienne, Georges, Michel, Dijk, Derk-Jan, Maquet, Pierre, Visscher, Peter M and Vandewalle, Gilles (2021). Erratum: Alzheimer's disease genetic risk and sleep phenotypes in healthy young men: Association with more slow waves and daytime sleepiness (SLEEP DOI: 10.1093/sleep/zsaa137). Sleep, 44 (5) zsaa137. doi: 10.1093/sleep/zsab079

Erratum: Alzheimer's disease genetic risk and sleep phenotypes in healthy young men: Association with more slow waves and daytime sleepiness (SLEEP DOI: 10.1093/sleep/zsaa137)

2021

Journal Article

Symptom-level modelling unravels the shared genetic architecture of anxiety and depression

Thorp, Jackson G., Campos, Adrian I., Grotzinger, Andrew D., Gerring, Zachary F., An, Jiyuan, Ong, Jue-Sheng, Wang, Wei, Shringarpure, Suyash, Byrne, Enda M., MacGregor, Stuart, Martin, Nicholas G., Medland, Sarah E., Middeldorp, Christel M. and Derks, Eske M. (2021). Symptom-level modelling unravels the shared genetic architecture of anxiety and depression. Nature Human Behaviour, 5 (10), 1432-1442. doi: 10.1038/s41562-021-01094-9

Symptom-level modelling unravels the shared genetic architecture of anxiety and depression

2021

Journal Article

Comorbid chronic pain and depression: shared risk factors and differential antidepressant effectiveness

Roughan, William H., Campos, Adrián I., García-Marín, Luis M., Cuéllar-Partida, Gabriel, Lupton, Michelle K., Hickie, Ian B., Medland, Sarah E., Wray, Naomi R., Byrne, Enda M., Ngo, Trung Thanh, Martin, Nicholas G. and Rentería, Miguel E. (2021). Comorbid chronic pain and depression: shared risk factors and differential antidepressant effectiveness. Frontiers in Psychiatry, 12 643609, 1-13. doi: 10.3389/fpsyt.2021.643609

Comorbid chronic pain and depression: shared risk factors and differential antidepressant effectiveness

2021

Journal Article

Can network analysis of self-reported psychopathology shed light on the core phenomenology of bipolar disorders in adolescents and young adults?

Scott, Jan, Crouse, Jacob J., Ho, Nicholas, Carpenter, Joanne, Martin, Nicholas, Medland, Sarah, Parker, Richard, Byrne, Enda, Couvy-Duchesne, Baptiste, Mitchell, Brittany, Merikangas, Kathleen, Gillespie, Nathan A. and Hickie, Ian (2021). Can network analysis of self-reported psychopathology shed light on the core phenomenology of bipolar disorders in adolescents and young adults?. Bipolar Disorders, 23 (6), 584-594. doi: 10.1111/bdi.13067

Can network analysis of self-reported psychopathology shed light on the core phenomenology of bipolar disorders in adolescents and young adults?

2021

Journal Article

GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression

Wu, Yeda, Murray, Graham K., Byrne, Enda M., Sidorenko, Julia, Visscher, Peter M. and Wray, Naomi R. (2021). GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression. Nature Communications, 12 (1) 1146, 1-17. doi: 10.1038/s41467-021-21280-7

GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression

2021

Journal Article

Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

Blokland, Gabriëlla A.M., Grove, Jakob, Chen, Chia-Yen, Cotsapas, Chris, Tobet, Stuart, Handa, Robert, Ripke, Stephan, Neale, Benjamin M., Corvin, Aiden, Walters, James T.R., Farh, Kai-How, Holmans, Peter A., Lee, Phil, Bulik-Sullivan, Brendan, Collier, David A., Huang, Hailiang, Pers, Tune H., Agartz, Ingrid, Agerbo, Esben, Albus, Margot, Alexander, Madeline, Amin, Farooq, Bacanu, Silviu A., Begemann, Martin, Belliveau, Richard A., Bene, Judit, Bergen, Sarah E., Bevilacqua, Elizabeth, Bigdeli, Tim B. ... iPSYCH (2021). Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Biological Psychiatry, 91 (1), 102-117. doi: 10.1016/j.biopsych.2021.02.972

Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

2021

Journal Article

Schizophrenia polygenic risk scores in youth mental health: preliminary associations with diagnosis, clinical stage and functioning

Crouse, Jacob J., Carpenter, Joanne S., Iorfino, Frank, Lin, Tian, Ho, Nicholas, Byrne, Enda M., Henders, Anjali K., Wallace, Leanne, Hermens, Daniel F., Scott, Elizabeth M., Wray, Naomi R. and Hickie, Ian B. (2021). Schizophrenia polygenic risk scores in youth mental health: preliminary associations with diagnosis, clinical stage and functioning. BJPsych Open, 7 (2) e58, e58. doi: 10.1192/bjo.2021.14

Schizophrenia polygenic risk scores in youth mental health: preliminary associations with diagnosis, clinical stage and functioning

2021

Journal Article

A meta-analysis of the relationship between subjective sleep and depressive symptoms in adolescence

O’Callaghan, Victoria S., Couvy-Duchesne, Baptiste, Strike, Lachlan T., McMahon, Katie L., Byrne, Enda M. and Wright, Margaret J. (2021). A meta-analysis of the relationship between subjective sleep and depressive symptoms in adolescence. Sleep Medicine, 79, 134-144. doi: 10.1016/j.sleep.2021.01.011

A meta-analysis of the relationship between subjective sleep and depressive symptoms in adolescence

2020

Other Outputs

Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors

Mullins, Niamh, Kang, Jooeun, Campos, Adrian I, Coleman, Jonathan R I, Edwards, Alexis C, Galfalvy, Hanga, Levey, Daniel F, Lori, Adriana, Shabalin, Andrey, Starnawska, Anna, Su, Mei-Hsin, Watson, Hunna J, Adams, Mark, Awasthi, Swapnil, Gandal, Michael, Hafferty, Jonathan D, Hishimoto, Akitoyo, Kim, Minsoo, Okazaki, Satoshi, Otsuka, Ikuo, Ripke, Stephan, Ware, Erin B, Bergen, Andrew W, Berrettini, Wade H, Bohus, Martin, Brandt, Harry, Chang, Xiao, Chen, Wei J, Chen, Hsi-Chung ... Ruderfer, Douglas M (2020). Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors. doi: 10.1101/2020.12.01.20241281

Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors

2020

Journal Article

Short communication: Self-reported sleep-wake disturbances preceding onset of full-threshold mood and/or psychotic syndromes in community residing adolescents and young adults

Scott, Jan, Byrne, Enda, Medland, Sarah and Hickie, Ian (2020). Short communication: Self-reported sleep-wake disturbances preceding onset of full-threshold mood and/or psychotic syndromes in community residing adolescents and young adults. Journal of Affective Disorders, 277, 592-595. doi: 10.1016/j.jad.2020.08.083

Short communication: Self-reported sleep-wake disturbances preceding onset of full-threshold mood and/or psychotic syndromes in community residing adolescents and young adults

2020

Journal Article

A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

Shen, Xueyi, Howard, David M., Adams, Mark J., Hill, W. David, Clarke, Toni-Kim, Adams, Mark J., Clarke, Toni-Kim, McIntosh, Andrew M., Deary, Ian J., Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Agerbo, Esben, Air, Tracy M., Andlauer, Till F. M., Bacanu, Silviu-Alin, Bækvad-Hansen, Marie, Beekman, Aartjan T. F., Bigdeli, Tim B., Binder, Elisabeth B., Bryois, Julien, Buttenschøn, Henriette N., Bybjerg-Grauholm, Jonas, Cai, Na, Castelao, Enrique, Christensen, Jane Hvarregaard ... McIntosh, Andrew M. (2020). A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank. Nature Communications, 11 (1) 2301. doi: 10.1038/s41467-020-16022-0

A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

2020

Conference Publication

Symptom-level genetic modelling identifies novel risk loci and unravels the shared genetic architecture of anxiety and depression

Thorp, Jackson G., Campos, Adrian I., Grotzinger, Andrew D., Gerring, Zachary, An, Jiyuan, Ong, Jue-Sheng, Wang, Wei, Shringarpure, Suyash, Byrne, Enda M., MacGregor, Stuart, Martin, Nicholas G., Medland, Sarah E., Middeldorp, Christel M. and Derks, Eske M. (2020). Symptom-level genetic modelling identifies novel risk loci and unravels the shared genetic architecture of anxiety and depression. 50th Annual Meeting of the Behavior-Genetics-Association (BGA), Electr Network, Jun 26, 2020. NEW YORK: SPRINGER.

Symptom-level genetic modelling identifies novel risk loci and unravels the shared genetic architecture of anxiety and depression

2020

Conference Publication

The relationship between comorbid chronic pain and poorer self-reported antidepressant efficacy is partly mediated by genetics

Campos, Adrián I., Roughan, William H., García-Marin, Luis M., Cuéllar-Partida, Gabriel, Lupton, Michelle K., Hickie, Ian B., Medland, Sarah E., Wray, Naomi R., Byrne, Enda M., Ngo, Trung T., Martin, Nicholas G. and Rentería, Miguel E. (2020). The relationship between comorbid chronic pain and poorer self-reported antidepressant efficacy is partly mediated by genetics. Virtual 2020 World Congress of Psychiatric Genetics (WCPG), Online, 16–22 October 2020.

The relationship between comorbid chronic pain and poorer self-reported antidepressant efficacy is partly mediated by genetics

2020

Journal Article

Refining attention-deficit/hyperactivity disorder and autism spectrum disorder genetic loci by integrating summary data from genome-wide association, gene expression and DNA methylation studies

Hammerschlag, Anke R., Byrne, Enda M., Bartels, Meike, Wray, Naomi R., Middeldorp, Christel M., eQTLGen Consortium, BIOS Consortium, Ahsan, Habibul, Alves, Isabel, Andiappan, Anand, Arindrarto, Wibowo, Awadalla, Philip, Battle, Alexis, Beutner, Frank, Bonder, Marc Jan, Boomsma, Dorret I., Christiansen, Mark, Claringbould, Annique, Deelen, Patrick, Esko, Tõnu, Favé, Marie-Julie, Franke, Lude, Frayling, Timothy, Gharib, Sina A., Gibson, Gregory, Heijmans, Bastiaan T., Hemani, Gibran, Jansen, Rick, Kähönen, Mika, Kalnapenkis, Anette ... Agbessi, Mawussé (2020). Refining attention-deficit/hyperactivity disorder and autism spectrum disorder genetic loci by integrating summary data from genome-wide association, gene expression and DNA methylation studies. Biological Psychiatry, 88 (6), 470-479. doi: 10.1016/j.biopsych.2020.05.002

Refining attention-deficit/hyperactivity disorder and autism spectrum disorder genetic loci by integrating summary data from genome-wide association, gene expression and DNA methylation studies

2020

Journal Article

Genetic control of temperament traits across species: association of autism spectrum disorder risk genes with cattle temperament

Costilla, Roy, Kemper, Kathryn E., Byrne, Enda M., Porto-Neto, Laercio R., Carvalheiro, Roberto, Purfield, Deirdre C., Doyle, Jennifer L., Berry, Donagh P., Moore, Stephen S., Wray, Naomi R. and Hayes, Ben J. (2020). Genetic control of temperament traits across species: association of autism spectrum disorder risk genes with cattle temperament. Genetics Selection Evolution, 52 (1) 51, 51. doi: 10.1186/s12711-020-00569-z

Genetic control of temperament traits across species: association of autism spectrum disorder risk genes with cattle temperament

2020

Journal Article

Cohort profile: the Australian genetics of depression study

Byrne, Enda M., Kirk, Katherine M., Medland, Sarah E., McGrath, John J., Colodro-Conde, Lucia, Parker, Richard, Cross, Simone, Sullivan, Lenore, Statham, Dixie J., Levinson, Douglas F., Licinio, Julio, Wray, Naomi R, Hickie, Ian B. and Martin, Nicholas G. (2020). Cohort profile: the Australian genetics of depression study. BMJ Open, 10 (5) e032580, e032580. doi: 10.1136/bmjopen-2019-032580

Cohort profile: the Australian genetics of depression study

2020

Journal Article

Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders

Byrne, Enda M., Zhu, Zhihong, Qi, Ting, Skene, Nathan G., Bryois, Julien, Pardinas, Antonio F., Stahl, Eli, Bipolar Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Rietschel, Marcella, Smoller, Jordan W., Owen, Michael J., Walters, James T. R., O’Donovan, Michael C., McGrath, John G., Hjerling-Leffler, Jens, Sullivan, Patrick F., Goddard, Michael E., Visscher, Peter M., Yang, Jian and Wray, Naomi R. (2020). Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders. Molecular Psychiatry, 26 (6), 2070-2081. doi: 10.1038/s41380-020-0705-9

Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders

2020

Journal Article

Minimal phenotyping yields genome-wide association signals of low specificity for major depression

Cai, Na, Revez, Joana A., Adams, Mark J., Andlauer, Till F. M., Breen, Gerome, Byrne, Enda M., Clarke, Toni-Kim, Forstner, Andreas J., Grabe, Hans J., Hamilton, Steven P., Levinson, Douglas F., Lewis, Cathryn M., Lewis, Glyn, Martin, Nicholas G., Milaneschi, Yuri, Mors, Ole, Müller-Myhsok, Bertram, Penninx, Brenda W. J. H., Perlis, Roy H., Pistis, Giorgio, Potash, James B., Preisig, Martin, Shi, Jianxin, Smoller, Jordan W., Streit, Fabien, Tiemeier, Henning, Uher, Rudolf, Van der Auwera, Sandra, Viktorin, Alexander ... Flint, Jonathan (2020). Minimal phenotyping yields genome-wide association signals of low specificity for major depression. Nature Genetics, 52 (4), 437-447. doi: 10.1038/s41588-020-0594-5

Minimal phenotyping yields genome-wide association signals of low specificity for major depression