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2012

Journal Article

Unraveling the genetic etiology of adult antisocial behavior: a genome-wide association study

Tielbeek, Jorim J., Medland, Sarah E., Benyamin, Beben, Byrne, Enda M., Heath, Andrew C., Madden, Pamela A. F., Martin, Nicholas G., Wray, Naomi R. and Verweij, Karin J. H. (2012). Unraveling the genetic etiology of adult antisocial behavior: a genome-wide association study. PLoS One, 7 (10) e45086, e1005378-e1005378. doi: 10.1371/journal.pone.0045086

Unraveling the genetic etiology of adult antisocial behavior: a genome-wide association study

2012

Journal Article

Appraisals of stressful life events as a genetically-linked mechanism in the stress-depression relationship

Conway, Christopher C., Hammen, Constance, Espejo, Emmanuel P., Wray, Naomi R., Najman, Jake M. and Brennan, Patricia A. (2012). Appraisals of stressful life events as a genetically-linked mechanism in the stress-depression relationship. Cognitive Therapy and Research, 36 (4), 338-347. doi: 10.1007/s10608-011-9368-9

Appraisals of stressful life events as a genetically-linked mechanism in the stress-depression relationship

2012

Journal Article

Using summary data from the Danish National Registers to estimate heritabilities for schizophrenia, bipolar disorder, and major depressive disorder

Wray, Naomi R. and Gottesman, Irving I. (2012). Using summary data from the Danish National Registers to estimate heritabilities for schizophrenia, bipolar disorder, and major depressive disorder. Frontiers in Applied Genetic Epidemiology, 3 (118) Article 118, 118. doi: 10.3389/fgene.2012.00118

Using summary data from the Danish National Registers to estimate heritabilities for schizophrenia, bipolar disorder, and major depressive disorder

2012

Journal Article

Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs (vol 44, pg 247, 2012)

Lee, S. Hong, DeCandia, Teresa R., Ripke, Stephan, Yang, Jian, Sullivan, Patrick F., Goddard, Michael E., Keller, Matthew C., Visscher, Peter M. and Wray, Naomi R. (2012). Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs (vol 44, pg 247, 2012). Nature Genetics, 44 (7), 831-831. doi: 10.1038/ng0712-831a

Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs (vol 44, pg 247, 2012)

2012

Journal Article

Impact of diagnostic misclassification on estimation of genetic correlations using genome-wide genotypes

Wray, Naomi R., Lee, Sang Hong and Kendler, Kenneth S. (2012). Impact of diagnostic misclassification on estimation of genetic correlations using genome-wide genotypes. European Journal of Human Genetics, 20 (6), 668-674. doi: 10.1038/ejhg.2011.257

Impact of diagnostic misclassification on estimation of genetic correlations using genome-wide genotypes

2012

Journal Article

Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion (vol 2, e125, 2012)

Vinkhuyzen, A. A. E., Pedersen, N. L., Yang, J., Lee, S. H., Magnusson, P. K. E., Iacono, W. G., McGue, M., Madden, P. A. F., Heath, A. C., Luciano, M., Payton, A., Horan, M., Ollier, W., Pendleton, N., Deary, I. J., Montgomery, G. W., Martin, N. G., Visscher, P. M. and Wray, N. R. (2012). Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion (vol 2, e125, 2012). Translational Psychiatry, 2 (5) e125, e125-e125. doi: 10.1038/tp.2012.49

Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion (vol 2, e125, 2012)

2012

Journal Article

A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales

Service, S. K., Verweij, K. J. H., Lahti, J., Congdon, E., Ekelund, J., Hintsanen, M., Raikkonen, K., Lehtimaki, T., Kahonen, M., Widen, E., Taanila, A., Veijola, J., Heath, A. C., Madden, P. A. F., Montgomery, G. W., Sabatti, C., Jarvelin, M-R, Palotie, A., Raitakari, O., Viikari, J., Martin, N. G., Eriksson, J. G., Keltikangas-Jarvinen, L., Wray, N. R. and Freimer, N. B. (2012). A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales. Translational Psychiatry, 2 (5) e116, e116-e116. doi: 10.1038/tp.2012.37

A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales

2012

Journal Article

Meta-analyses of genome-wide linkage scans of anxiety-related phenotypes

Webb, Bradley T., Guo, An-Yuan, Maher, Brion S., Zhao, Zhongming, van den Oord, Edwin J., Kendler, Kenneth S., Riley, Brien P., Gillespie, Nathan A., Prescott, Carol A., Middeldorp, Christel M., Willemsen, Gonneke, de Geus, Eco J. C., Hottenga, Jouke-Jan, Boomsma, Dorret I., Slagboom, Eline P., Wray, Naomi R., Montgomery, Grant W., Martin, Nicholas G., Wright, Margie J., Heath, Andrew C., Madden, Pamela A., Gelernter, Joel, Knowles, James A., Hamilton, Steven P., Weissman, Myrna M., Fyer, Abby J., Huezo-Diaz, Patricia, McGuffin, Peter, Farmer, Anne ... Hettema, John M. (2012). Meta-analyses of genome-wide linkage scans of anxiety-related phenotypes. European Journal of Human Genetics, 20 (10), 1078-1084. doi: 10.1038/ejhg.2012.47

Meta-analyses of genome-wide linkage scans of anxiety-related phenotypes

2012

Journal Article

A better coefficient of determination for genetic profile analysis

Lee, Sang Hong, Goddard, Michael E., Wray, Naomi R. and Visscher, Peter M. (2012). A better coefficient of determination for genetic profile analysis. Genetic Epidemiology, 36 (3), 214-224. doi: 10.1002/gepi.21614

A better coefficient of determination for genetic profile analysis

2012

Journal Article

Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion

Vinkhuyzen, A. A. E., Pedersen, N. L., Yang, J., Lee, S. H., Magnusson, P. K. E., Iacono, W. G., McGue, M., Madden, P. A. F., Heath, A. C., Luciano, M., Payton, A., Horan, M., Ollier, W., Pendleton, N., Deary, I. J., Montgomery, G. W., Martin, N. G., Visscher, P. M. and Wray, N. R. (2012). Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion. Translational Psychiatry, 2 (e102) 201227, e102-e102. doi: 10.1038/tp.2012.27

Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion

2012

Journal Article

Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs

Lee, S. Hong, DeCandia, Teresa R., Ripke, Stephan, Yang, Jian, Sullivan, Patrick F ., Goddard, Michael E ., Keller, Matthew C ., Visscher, Peter M ., Wray, Naomi R., Schizophrenia Psychiat Genome-Wide, Int Schizophrenia Consortium ISC, Mol Genetics Schizophrenia and Mowry, Bryan (2012). Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs. Nature Genetics, 44 (3), 247-250. doi: 10.1038/ng.1108

Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs

2012

Journal Article

A bias-reducing pathway enrichment analysis of genome-wide association data confirmed association of the MHC region with schizophrenia

Jia, Peilin, Wang, Lily, Fanous, Ayman H., Chen, Xiangning, Kendler, Kenneth S., Zhao, Zhongming, Morris, Derek W., O'Dushlaine, Colm T., Kenny, Elaine, Quinn, Emma M., Gill, Michael, Corvin, Aiden, O'Donovan, Michael C., Kirov, George K., Craddock, Nick J., Holmans, Peter A., Williams, Nigel M., Georgieva, Lucy, Nikolov, Ivan, Norton, N., Williams, H., Toncheva, Draga, Milanova, Vihra, Owen, Michael J., Hultman, Christina M., Lichtenstein, Paul, Thelander, Emma F., Sullivan, Patrick, McQuillin, Andrew ... Sklar, Pamela (2012). A bias-reducing pathway enrichment analysis of genome-wide association data confirmed association of the MHC region with schizophrenia. Journal of Medical Genetics, 49 (2), 96-103. doi: 10.1136/jmedgenet-2011-100397

A bias-reducing pathway enrichment analysis of genome-wide association data confirmed association of the MHC region with schizophrenia

2012

Journal Article

Genetic co-morbidity between neuroticism, anxiety/depression and somatic distress in a population sample of adolescent and young adult twins

Hansell, N. K., Wright, M. J., Medland, S. E., Davenprot, T. A., Wray, N. R., Martin, N. G. and Hickie, I. B. (2012). Genetic co-morbidity between neuroticism, anxiety/depression and somatic distress in a population sample of adolescent and young adult twins. Psychological Medicine, 42 (6), 1249-1260. doi: 10.1017/S0033291711002431

Genetic co-morbidity between neuroticism, anxiety/depression and somatic distress in a population sample of adolescent and young adult twins

2012

Journal Article

Don't give up on GWAS

Sullivan, P., on behalf of 96 Psychiatric Genetics Investigators, McGrath, John J., Mowry, Bryan and Wray, Naomi (2012). Don't give up on GWAS. Molecular Psychiatry, 17 (1), 2-3. doi: 10.1038/mp.2011.94

Don't give up on GWAS

2012

Journal Article

Evidence-based psychiatric genetics, AKA the false dichotomy between common and rare variant hypotheses

Visscher, Peter, Goddard, M. E., Derks, E. M. and Wray, Naomi (2012). Evidence-based psychiatric genetics, AKA the false dichotomy between common and rare variant hypotheses. Molecular Psychiatry, 17 (5), 474-485. doi: 10.1038/mp.2011.65

Evidence-based psychiatric genetics, AKA the false dichotomy between common and rare variant hypotheses

2012

Journal Article

Genome-wide association study of major depressive disorder: New results, meta-analysis, and lessons learned

Wray, N. R., Pergadia, M. L., Blackwood, D. H. R., Penninx, B. W. J. H., Gordon, S. D., Nyholt, D. R., Ripke, S., MacIntyre, D. J., McGhee, K. A., MacLean, A. W., Smit, J. H., Hottenga, J. J., Willemsen, G., Middeldorp, C. M., De Geus, E. J. C., Lewis, C. M., McGuffin, P., Hickie, I. B., Van Den Oord, E. J. C. G., Liu, J. Z., MacGregor, S., McEvoy, B. P., Byrne, E. M., Medland, S. E., Statham, D. J., Henders, A. K., Heath, A. C., Montgomery, G. W., Martin, N. G. ... Sullivan, P. F. (2012). Genome-wide association study of major depressive disorder: New results, meta-analysis, and lessons learned. Molecular Psychiatry, 17 (1), 36-48. doi: 10.1038/mp.2010.109

Genome-wide association study of major depressive disorder: New results, meta-analysis, and lessons learned

2011

Journal Article

Underestimated Effect Sizes in GWAS: Fundamental Limitations of Single SNP Analysis for Dichotomous Phenotypes

Stringer, Sven, Wray, Naomi R, Kahn, Rene S and Derks, Eske M (2011). Underestimated Effect Sizes in GWAS: Fundamental Limitations of Single SNP Analysis for Dichotomous Phenotypes. PLoS One, 6 (11) e27964, e27964. doi: 10.1371/journal.pone.0027964

Underestimated Effect Sizes in GWAS: Fundamental Limitations of Single SNP Analysis for Dichotomous Phenotypes

2011

Journal Article

GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia

Chen, X., Lee, G., Maher, B. S., Fanous, A. H., Chen, J., Zhao, Z., Guo, A., van den Oord, E., Sullivan, P. F., Shi, J., Levinson, D. F., Gejman, P. V., Sanders, A., Duan, J., Owen, M. J., Craddock, N. J., O'Donovan, M. C., Blackman, J., Lewis, D., Kirov, G. K., Qin, W., Schwab, S., Wildenauer, D., Chowdari, K., Nimgaonkar, V., Straub, R. E., Weinberger, D. R., O'Neill, F. A., Walsh, D. ... Visscher, Peter M. (2011). GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia. Molecular Psychiatry, 16 (11), 1117-1129. doi: 10.1038/mp.2010.96

GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia

2011

Journal Article

Two non-synonymous markers in PTPN21, identified by genome-wide association study data-mining and replication, are associated with schizophrenia

Chen, Jingchun, Lee, Grace, Fanous, Ayman H., Zhao, Zhongming, Jia, Peilin, O'neill, Anthony, Walsh, Dermot, Kendler, Kenneth S., Chen, Xiangning, O’Donovan, Michael C., Kirov, George K, Craddock, Nick J, Holmans, Peter A, Williams, Nigel M, Georgieva, Lyudmila, Nikolov, Ivan, Norton, N., Williams, H., Toncheva, Draga, Milanova, Vihra, Owen, Michael J, Hultman, Christina M, Lichtenstein, Paul, Thelander, Emma F, Sullivan, Patrick, Morris, Derek W, O’Dushlaine, Colm T., Kenny, Elaine, Quinn, Emma M ... Scolnick, Edward M (2011). Two non-synonymous markers in PTPN21, identified by genome-wide association study data-mining and replication, are associated with schizophrenia. Schizophrenia Research, 131 (1-3), 43-51. doi: 10.1016/j.schres.2011.06.023

Two non-synonymous markers in PTPN21, identified by genome-wide association study data-mining and replication, are associated with schizophrenia

2011

Journal Article

Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM

Amin, N., Byrne, E., Johnson, J., Chenevix-Trench, G., Walter, S., Nolte, I. M., kConFab Investigators, Vink, J.M., Rawal, R., Mangino, M., Teumer, A., Keers, J. C., Verwoert, G., Baumeister, S., Biffar, R., Petersmann, A., Dahmen, N., Doering, A., Isaacs, A., Broer, L., Wray, N. R., Montgomery, G. W., Levy, D., Psaty, B. M., Gudnason, V., Chakravarti, A., Sulem, P., Gudbjartsson, D. F., Kiemeney, L. A. ... van Duijn, C. M. (2011). Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM. Molecular Psychiatry, 17 (11), 1116-1129. doi: 10.1038/mp.2011.101

Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM