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2025 Journal Article Population-representative inference for primary and secondary outcomes in extended case-cohort designsWimberley, Theresa, Plana-Ripoll, Oleguer, Pedersen, Carsten B., Pedersen, Marianne G., Dreier, Julie W., Christensen, Jakob, Horsdal, Henriette Thisted, Astrup, Aske, Thompson, Wesley K., Helenius, Dorte, McGrath, John J., Wray, Naomi R., Petersen, Liselotte Vogdrup, Vilhjálmsson, Bjarni, Mortensen, Preben B. and Agerbo, Esben (2025). Population-representative inference for primary and secondary outcomes in extended case-cohort designs. Discover public health, 22 (1) 599. doi: 10.1186/s12982-025-00888-w |
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2025 Journal Article Multi-ancestry genome-wide association analyses incorporating SNP-by-psychosocial interactions identify novel loci for serum lipidsBentley, Amy R., Brown, Michael R., Musani, Solomon K., Schwander, Karen L., Winkler, Thomas W., Sims, Mario, Kilpeläinen, Tuomas O., Aschard, Hugues, Bartz, Traci M., Bielak, Lawrence F., Chai, Jin-Fang, Chitrala, Kumaraswamy Naidu, Franceschini, Nora, Graff, Mariaelisa, Guo, Xiuqing, Hartwig, Fernando P., Horimoto, Andrea R.V.R., Lim, Elise, Liu, Yongmei, Manning, Alisa K., Nolte, Ilja M., Noordam, Raymond, Richard, Melissa A., Smith, Albert V., Sung, Yun Ju, Vojinovic, Dina, Wang, Rujia, Wang, Yujie, Feitosa, Mary F. ... Fox, Ervin R. (2025). Multi-ancestry genome-wide association analyses incorporating SNP-by-psychosocial interactions identify novel loci for serum lipids. Translational Psychiatry, 15 (1) 207, 1. doi: 10.1038/s41398-025-03418-z |
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2025 Journal Article Epigenetic profiles of tissue informative CpGs inform ALS disease status and progressionCaggiano, Christa, Morselli, Marco, Qian, Xiaoyu, Celona, Barbara, Thompson, Michael J., Wani, Shivangi, Tosevska, Anela, Taraszka, Kodi, Heuer, Galen, Ngo, Shyuan T., Steyn, Frederick J., Nestor, Peter J., Wallace, Leanne, Mccombe, Pamela, Heggie, Susan, Thorpe, Kathryn, Mcelligott, Caitlin, English, Gemyka, Henders, Anjali, Henderson, Robert, Lomen-Hoerth, Catherine, Wray, Naomi R., Mcrae, Allan F., Pellegrini, Matteo, Garton, Fleur C. and Zaitlen, Noah (2025). Epigenetic profiles of tissue informative CpGs inform ALS disease status and progression. Genome Medicine, 17 (1) 115. doi: 10.1186/s13073-025-01542-5 |
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2025 Conference Publication Refined mitochondrial DNA copy number (MTDNA-CN) calling and analysis pipeline reveals nuclear genetic regulation of MTDNA-CN in blood and its lack of association with mood disordersWang, Xiaotong, McGrath, Isabelle, Li, Ang and Wray, Naomi (2025). Refined mitochondrial DNA copy number (MTDNA-CN) calling and analysis pipeline reveals nuclear genetic regulation of MTDNA-CN in blood and its lack of association with mood disorders. World Congress of Psychiatric Genetics (WCPG), Cancun, Mexico, 19-23 October 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2025.08.402 |
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2025 Conference Publication Multi-ancestry conditional and joint analysis (MANC-COJO) of GWAS summary statisticsWang, Xiaotong, Wang, Yong, Visscher, Peter, Wray, Naomi and Yengo, Loic (2025). Multi-ancestry conditional and joint analysis (MANC-COJO) of GWAS summary statistics. World Congress of Psychiatric Genetics (WCPG), Cancun, Mexico, 19-23 October 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2025.08.136 |
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2025 Conference Publication Functional genomic investigation of the immune hypothesis of mental illnessMcGrath, Isabelle, Wray, Naomi and Lynall, Mary-Ellen (2025). Functional genomic investigation of the immune hypothesis of mental illness. World Congress of Psychiatric Genetics (WCPG), Cancun, Mexico, 19-23 October 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2025.08.210 |
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2025 Conference Publication The genetic architecture of difficult-to-treat depression: a Pharmlines initiative cohort studyWalker, Alicia, Klont, Frank, Bos, Jens, van Loo, Hanna, Taquet, Maxime, Hak, Eelko and Wray, Naomi (2025). The genetic architecture of difficult-to-treat depression: a Pharmlines initiative cohort study. World Congress of Psychiatric Genetics (WCPG), Cancun, Mexico, 19-23 October 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2025.08.409 |
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2025 Conference Publication Heterogeneity of major depressive disorder investigated through sustained fill of specific antidepressant scriptsWalker, Alicia, Mitchell, Brittany, Lin, Tian, Crouse, Jacob, Martin, Nick, Taquet, Maxime, Medland, Sarah E., Hickie, Ian and Wray, Naomi (2025). Heterogeneity of major depressive disorder investigated through sustained fill of specific antidepressant scripts. World Congress of Psychiatric Genetics (WCPG), Cancun, Mexico, 19-23 October 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2025.08.504 |
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2025 Conference Publication Towards improving reproducibility in psychiatric blood biomarker research: a framework for systematic identification and control of confounding factorsAlbinana, Clara, Shin, Mirim, Crouse, Jacob J., Hickie, Ian B. and Wray, Naomi (2025). Towards improving reproducibility in psychiatric blood biomarker research: a framework for systematic identification and control of confounding factors. World Congress of Psychiatric Genetics (WCPG), Cancun, Mexico, 19-23 October 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2025.08.315 |
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2025 Conference Publication Biobank-scale proteomic estimates of circadian dysregulation increase risk of bipolar disorder, schizophrenia and depressionAlbinana, Clara, Zeng, Yanni, Crouse, Jacob J., Hickie, Ian B., Gachon, Frederic and Wray, Naomi (2025). Biobank-scale proteomic estimates of circadian dysregulation increase risk of bipolar disorder, schizophrenia and depression. World Congress of Psychiatric Genetics (WCPG), Cancun, Mexico, 19-23 October 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2025.08.177 |
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2025 Journal Article Publisher Correction: Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genesvan der Laan, Camiel M., Ip, Hill F., Schipper, Marijn, Hottenga, Jouke-Jan, St Pourcain, Beate, Zayats, Tetyana, Pool, René, Krapohl, Eva M. L., Brikell, Isabell, Soler Artigas, María, Cabana-Domínguez, Judit, Llonga, Natalia, Nolte, Ilja M., Bolhuis, Koen, Palviainen, Teemu, Zafarmand, Hadi, Gordon, Scott, Aliev, Fazil, Burt, S. Alexandra, Wang, Carol A., Saunders, Gretchen, Karhunen, Ville, Adkins, Daniel E., Border, Richard, Peterson, Roseann E., Prinz, Joseph A., Thiering, Elisabeth, Vilor-Tejedor, Natàlia, Ahluwalia, Tarunveer S. ... Boomsma, Dorret I. (2025). Publisher Correction: Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genes. Nature Genetics, 57 (10), 1-1. doi: 10.1038/s41588-025-02383-z |
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2025 Journal Article Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genesvan der Laan, Camiel M., Ip, Hill F., Schipper, Marijn, Hottenga, Jouke-Jan, St Pourcain, Beate, Zayats, Tetyana, Pool, René, Krapohl, Eva M. L., Brikell, Isabell, Soler Artigas, María, Cabana-Domínguez, Judit, Nolte, Ilja M., Bolhuis, Koen, Palviainen, Teemu, Zafarmand, Hadi, Gordon, Scott, Aliev, Fazil, Burt, S. Alexandra, Wang, Carol A., Saunders, Gretchen, Karhunen, Ville, Adkins, Daniel E., Border, Richard, Peterson, Roseann E., Prinz, Joseph A., Thiering, Elisabeth, Vilor-Tejedor, Natàlia, Ahluwalia, Tarunveer S., Allegrini, Andrea ... Llonga, Natalia (2025). Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genes. Nature Genetics, 57 (10), 2427-2435. doi: 10.1038/s41588-025-02295-y |
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2025 Journal Article A methylome-wide association study of major depression with out-of-sample case-control classification and trans-ancestry comparisonShen, Xueyi, Barbu, Miruna, Caramaschi, Doretta, Arathimos, Ryan, Czamara, Darina, David, Friederike S., Dearman, Anna, Dilkes, Evelyn, Herrera-Rivero, Marisol, Huider, Floris, Kuhn, Luise, Lu, Kuan-Chen, Palviainen, Teemu, Schowe, Alicia M., Shireby, Gemma, Weihs, Antoine, Wong, Chloe C. Y., Davyson, Eleanor, Casey, Hannah, Adams, Mark J., Allgaier, Antje-Kathrin, Barber, Michael, Burrage, Joe, Caspi, Avshalom, Costeira, Ricardo, Dunn, Erin C., Feldmann, Lisa, Frank, Josef, Freisleder, Franz J. ... Mcintosh, Andrew M. (2025). A methylome-wide association study of major depression with out-of-sample case-control classification and trans-ancestry comparison. Nature Mental Health, 3 (10), 1152-1167. doi: 10.1038/s44220-025-00486-4 |
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2025 Journal Article White blood cell proportions are associated with response to psychosocial therapy in young people at ultra-high risk for psychosisBarker, Lauren F., McRae, Allan F., Yuen, Hok Pan, Henders, Anjali K., Wallace, Leanne M., Lin, Tian, Phassouliotis, Christina, Spark, Jessica, Kerr, Melissa, Byrne, Enda M., Amminger, G. Paul, Nelson, Barnaby, Wray, Naomi R. and McGorry, Patrick D. (2025). White blood cell proportions are associated with response to psychosocial therapy in young people at ultra-high risk for psychosis. Biological Psychiatry Global Open Science, 5 (5) 100546, 1-11. doi: 10.1016/j.bpsgos.2025.100546 |
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2025 Conference Publication Mental Health and Sleep Correlates of Self-Reported Outdoor Daylight Exposure in Over 13,000 Adults With DepressionCrouse, Jacob, Park, Shin Ho, Mitchell, Brittany, Byrne, Enda, Medland, Sarah, Lin, Tian, Scott, Jan, de Haan, Zsofi, Tonini, Emiliana, Iorfino, Frank, Wray, Naomi, Martin, Nicholas and Hickie, Ian (2025). Mental Health and Sleep Correlates of Self-Reported Outdoor Daylight Exposure in Over 13,000 Adults With Depression. HOBOKEN: WILEY. |
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2025 Conference Publication Distinct Clinical, Metabolic-Inflammatory-Genetic Characteristics and Treatment Responses of Atypical DepressionShin, Mirim, Crouse, Jacob J., Lin, Tian, Byrne, Enda M., Mitchell, Brittany L., Lind, Penelope A., Parker, Richard, McKenna, Sarah, Tonini, Emiliana, Carpenter, Joanne S., Wray, Naomi, Medland, Sarah E., Martin, Nicholas G. and Hickie, Ian B. (2025). Distinct Clinical, Metabolic-Inflammatory-Genetic Characteristics and Treatment Responses of Atypical Depression. HOBOKEN: WILEY. |
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2025 Journal Article Large-scale GWAS of strabismus identifies risk loci and provides support for a link with maternal smokingHe, Weixiong, van der Most, Peter J., Ong, Jue-Sheng, Hwang, Liang-Dar, Wu, Yeda, Magnø, Morten S., Vehof, Jelle, Krebs, Kristi, Mauring, Laura, Õunap, Katrin, Abner, Erik, Martin, Nicholas G., Plotnikov, Denis, Jiang, Chen, Melles, Ronald B., Gharahkhani, Puya, Snieder, Harold, Palumaa, Teele, Kaljurand, Kuldar, Guggenheim, Jeremy A., Mackey, David A., Engle, Elizabeth C., Choquet, Hélène, MacGregor, Stuart, Lifelines Cohort Study, Aguirre-Gamboa, Raul, Deelen, Patrick, Franke, Lude, Kuivenhoven, Jan A. ... Wray, Naomi (2025). Large-scale GWAS of strabismus identifies risk loci and provides support for a link with maternal smoking. Nature Communications, 16 (1) 7890, 1-14. doi: 10.1038/s41467-025-62456-9 |
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2025 Journal Article Insulin resistance as an early marker in youth with mood disordersShin, Mirim, Crouse, Jacob J., Weger, Meltem, McKenna, Sarah, Wray, Naomi R., Scott, Elizabeth M., Hickie, Ian B. and Gachon, Frédéric (2025). Insulin resistance as an early marker in youth with mood disorders. Nature Mental Health, 3 (9), 1-3. doi: 10.1038/s44220-025-00472-w |
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2025 Journal Article Genomic risk prediction for depression in a large prospective study of older adults of European descentYu, Chenglong, Bakshi, Andrew, Agustini, Bruno, Walker, Alicia, Lin, Tian, Lotfaliany, Mojtaba, Williams, Lana J., McNeil, John J., Wray, Naomi R., Berk, Michael and Lacaze, Paul (2025). Genomic risk prediction for depression in a large prospective study of older adults of European descent. Molecular Psychiatry. doi: 10.1038/s41380-025-03145-3 |
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2025 Journal Article Absolute and relative risks of mental disorders in families: a Danish register-based studyPedersen, Carsten Bøcker, Pedersen, Marianne Giørtz, Antonsen, Sussie, Pedersen, Emil Michael, Horsdal, Henriette Thisted, Debost, Jean-Christophe, Mortensen, Preben Bo, Petersen, Liselotte Vogdrup, Vilhjálmsson, Bjarni J, Nielsen, Jørgen Feldbæk, Due, Jeppe Klok, Søgaard, Anders, Igel, Christian, Thompson, Wesley K, Fan, Chun Chieh, Wray, Naomi R, McGrath, John J and Agerbo, Esben (2025). Absolute and relative risks of mental disorders in families: a Danish register-based study. The Lancet Psychiatry, 12 (8), 590-599. doi: 10.1016/S2215-0366(25)00196-8 |
